TW200637873A - Antibodies against interleukin-1 beta - Google Patents
Antibodies against interleukin-1 betaInfo
- Publication number
- TW200637873A TW200637873A TW095103137A TW95103137A TW200637873A TW 200637873 A TW200637873 A TW 200637873A TW 095103137 A TW095103137 A TW 095103137A TW 95103137 A TW95103137 A TW 95103137A TW 200637873 A TW200637873 A TW 200637873A
- Authority
- TW
- Taiwan
- Prior art keywords
- antigen
- beta
- light chain
- antibodies against
- immunoglobulin molecules
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/245—IL-1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/567—Framework region [FR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/801—Drug, bio-affecting and body treating compositions involving antibody or fragment thereof produced by recombinant dna technology
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/867—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving immunoglobulin or antibody produced via recombinant dna technology
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Oncology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US64764305P | 2005-01-26 | 2005-01-26 | |
US75380005P | 2005-12-22 | 2005-12-22 | |
US11/335,907 US7566772B2 (en) | 2005-01-26 | 2006-01-19 | Antibodies against interleukin-1β |
Publications (1)
Publication Number | Publication Date |
---|---|
TW200637873A true TW200637873A (en) | 2006-11-01 |
Family
ID=36740960
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TW095103137A TW200637873A (en) | 2005-01-26 | 2006-01-26 | Antibodies against interleukin-1 beta |
Country Status (8)
Country | Link |
---|---|
US (2) | US7566772B2 (zh) |
EP (2) | EP1851245B1 (zh) |
AR (1) | AR052889A1 (zh) |
AU (1) | AU2006208286A1 (zh) |
CA (1) | CA2590164A1 (zh) |
ES (1) | ES2395953T3 (zh) |
TW (1) | TW200637873A (zh) |
WO (1) | WO2006081139A2 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102573893A (zh) * | 2009-05-29 | 2012-07-11 | 爱克索马技术有限公司 | IL-1β抗体及其结合片段的心血管相关用途 |
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EP2094306A2 (en) | 2006-12-20 | 2009-09-02 | XOMA Technology Ltd. | Treatment of il-1-beta related diseases |
EP2468301A1 (en) | 2007-05-29 | 2012-06-27 | Novartis AG | New indications for anti-IL-1-beta therapy |
JP2011505795A (ja) | 2007-11-27 | 2011-03-03 | ヴィヴェンティア バイオテクノロジーズ インコーポレーティッド | バリアントnfkbibの癌関連エピトープに対する抗体およびその使用 |
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-
2006
- 2006-01-19 EP EP06718993A patent/EP1851245B1/en not_active Not-in-force
- 2006-01-19 EP EP10183582A patent/EP2361933A3/en not_active Withdrawn
- 2006-01-19 AU AU2006208286A patent/AU2006208286A1/en not_active Abandoned
- 2006-01-19 ES ES06718993T patent/ES2395953T3/es active Active
- 2006-01-19 CA CA002590164A patent/CA2590164A1/en not_active Abandoned
- 2006-01-19 US US11/335,907 patent/US7566772B2/en not_active Expired - Fee Related
- 2006-01-19 WO PCT/US2006/002011 patent/WO2006081139A2/en active Application Filing
- 2006-01-25 AR ARP060100271A patent/AR052889A1/es unknown
- 2006-01-26 TW TW095103137A patent/TW200637873A/zh unknown
-
2009
- 2009-06-19 US US12/456,660 patent/US7964193B2/en not_active Expired - Fee Related
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102573893A (zh) * | 2009-05-29 | 2012-07-11 | 爱克索马技术有限公司 | IL-1β抗体及其结合片段的心血管相关用途 |
CN107243077A (zh) * | 2009-05-29 | 2017-10-13 | 爱克索马美国有限责任公司 | IL‑1β抗体及其结合片段的心血管相关用途 |
US10611832B2 (en) | 2009-05-29 | 2020-04-07 | Xoma (Us) Llc | Cardiovascular related uses of IL-1β antibodies and binding fragments thereof |
Also Published As
Publication number | Publication date |
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EP1851245A4 (en) | 2008-05-14 |
ES2395953T3 (es) | 2013-02-18 |
US7964193B2 (en) | 2011-06-21 |
AR052889A1 (es) | 2007-04-11 |
CA2590164A1 (en) | 2006-08-03 |
AU2006208286A1 (en) | 2006-08-03 |
US20100183616A1 (en) | 2010-07-22 |
US20070065439A1 (en) | 2007-03-22 |
EP1851245B1 (en) | 2012-10-10 |
WO2006081139A2 (en) | 2006-08-03 |
EP1851245A2 (en) | 2007-11-07 |
US7566772B2 (en) | 2009-07-28 |
EP2361933A2 (en) | 2011-08-31 |
WO2006081139A3 (en) | 2007-02-15 |
EP2361933A3 (en) | 2012-05-02 |
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