TR200003281T2 - CD-23'e karşı antikorlar, bunların türevleri ve terapötik kullanımları. - Google Patents

CD-23'e karşı antikorlar, bunların türevleri ve terapötik kullanımları.

Info

Publication number
TR200003281T2
TR200003281T2 TR2000/03281T TR200003281T TR200003281T2 TR 200003281 T2 TR200003281 T2 TR 200003281T2 TR 2000/03281 T TR2000/03281 T TR 2000/03281T TR 200003281 T TR200003281 T TR 200003281T TR 200003281 T2 TR200003281 T2 TR 200003281T2
Authority
TR
Turkey
Prior art keywords
antibodies
derivatives
therapeutic uses
rii
bind
Prior art date
Application number
TR2000/03281T
Other languages
English (en)
Turkish (tr)
Inventor
Marcel Paul Bonnefoy Jean-Yves
James Crowe Scott
Henry Ellis Jonathan
Timothy Rapson Nicholas
Shearin Jean
Original Assignee
Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited
Publication of TR200003281T2 publication Critical patent/TR200003281T2/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
TR2000/03281T 1998-05-09 1999-05-07 CD-23'e karşı antikorlar, bunların türevleri ve terapötik kullanımları. TR200003281T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9809839.5A GB9809839D0 (en) 1998-05-09 1998-05-09 Antibody

Publications (1)

Publication Number Publication Date
TR200003281T2 true TR200003281T2 (tr) 2001-03-21

Family

ID=10831668

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/03281T TR200003281T2 (tr) 1998-05-09 1999-05-07 CD-23'e karşı antikorlar, bunların türevleri ve terapötik kullanımları.

Country Status (25)

Country Link
US (1) US7008623B1 (sh)
EP (1) EP1076701A1 (sh)
JP (1) JP2002514421A (sh)
KR (1) KR20010043470A (sh)
CN (1) CN1308676A (sh)
AP (1) AP1547A (sh)
AU (1) AU763491B2 (sh)
BR (1) BR9910327A (sh)
CA (1) CA2328606A1 (sh)
EA (1) EA200001041A1 (sh)
EE (1) EE200000658A (sh)
GB (1) GB9809839D0 (sh)
HR (1) HRP20000762A2 (sh)
HU (1) HUP0102005A3 (sh)
ID (1) ID28088A (sh)
IL (1) IL139384A0 (sh)
IS (1) IS5696A (sh)
NO (1) NO20005632L (sh)
NZ (1) NZ507879A (sh)
PL (1) PL344019A1 (sh)
SK (1) SK16762000A3 (sh)
TR (1) TR200003281T2 (sh)
WO (1) WO1999058679A1 (sh)
YU (1) YU69000A (sh)
ZA (1) ZA200006312B (sh)

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US20040151721A1 (en) 2001-10-19 2004-08-05 O'keefe Theresa Humanized anti-CCR2 antibodies and methods of use therefor
WO2004002431A2 (en) * 2002-07-01 2004-01-08 Biogen, Inc. Humanized anti-lymphotoyin beta receptor antibodies
AR040778A1 (es) 2002-08-06 2005-04-20 Glaxo Group Ltd Anticuerpos alterados o fragmentos funcionales que se unen a mag (glicoproteina asociada a mielina).
GB0306309D0 (en) 2003-03-19 2003-04-23 Glaxo Group Ltd Method of treatment
WO2005000898A2 (en) 2003-06-27 2005-01-06 Biogen Idec Ma Inc. Use of hydrophobic-interaction-chromatography or hinge-region modifications for the production of homogeneous antibody-solutions
CA2434668A1 (en) 2003-07-04 2005-01-04 Laurence Mulard Novel approach to design glycopeptides based on o-specific polysaccharide of shigella flexneri serotype 2a
EP1631311A4 (en) * 2003-12-10 2007-04-11 Millennium Pharm Inc HUMANIZED ANTI-CCR2 ANTIBODIES AND METHOD OF USE
US7435799B2 (en) * 2004-01-08 2008-10-14 Applied Molecular Evolution TNF-α binding molecules
CA2560742A1 (en) 2004-03-23 2005-10-06 Biogen Idec Ma Inc. Receptor coupling agents and therapeutic uses thereof
US20060246075A1 (en) * 2004-09-29 2006-11-02 Marc Mercken Anti-amyloid antibodies, compositions, methods and uses
WO2006074399A2 (en) 2005-01-05 2006-07-13 Biogen Idec Ma Inc. Multispecific binding molecules comprising connecting peptides
CN101309704B (zh) 2005-11-14 2012-10-10 礼纳特神经***科学公司 针对降钙素基因相关肽的拮抗剂抗体及其使用方法
GB0525662D0 (en) 2005-12-16 2006-01-25 Glaxo Group Ltd Immunoglobulins
US7680868B2 (en) * 2005-12-20 2010-03-16 Roche Molecular Systems, Inc. PCR elbow determination by use of a double sigmoid function curve fit with the Levenburg-Marquardt algorithm and normalization
EP1804172B1 (en) * 2005-12-20 2021-08-11 Roche Diagnostics GmbH PCR elbow determination using curvature analysis of a double sigmoid
WO2009043051A2 (en) * 2007-09-27 2009-04-02 Biogen Idec Ma Inc. Cd23 binding molecules and methods of use thereof
US20090148905A1 (en) 2007-11-30 2009-06-11 Claire Ashman Antigen-binding constructs
CA2716424C (en) 2008-03-04 2015-04-28 Pfizer Limited Methods of treating chronic pain
EP2271323A2 (en) 2008-05-06 2011-01-12 Glaxo Group Limited Encapsulation of biologically active agents
CA2753332A1 (en) 2009-02-24 2010-09-02 Glaxo Group Limited Antigen-binding constructs
EP2401298A1 (en) 2009-02-24 2012-01-04 Glaxo Group Limited Antigen-binding constructs
WO2010097394A1 (en) 2009-02-24 2010-09-02 Glaxo Group Limited Multivalent and/or multispecific rankl-binding constructs
JP2012522749A (ja) 2009-04-01 2012-09-27 グラクソ グループ リミテッド 抗il−23免疫グロブリン
WO2010122090A1 (en) 2009-04-24 2010-10-28 Glaxo Group Limited Fgfr1c antibody combinations
AU2010288194B2 (en) 2009-08-28 2013-08-29 Teva Pharmaceuticals International Gmbh Methods for treating visceral pain by administering antagonist antibodies directed against calcitonin gene-related peptide
FR2957598B1 (fr) * 2010-03-17 2015-12-04 Lfb Biotechnologies Nouveau peptide signal, et son utilisation pour la production de proteines recombinantes
KR101947356B1 (ko) 2010-11-23 2019-02-12 글락소 그룹 리미티드 온코스타틴 m (osm)에 대한 항원 결합 단백질
MX2013005847A (es) 2010-11-24 2013-12-12 Glaxo Group Ltd Proteinas de union a antigeno multiespecificas que eligen como blanco a hgf.
US8974782B2 (en) 2011-02-07 2015-03-10 Glaxo Group Limited Treatment of stroke comprising anti-MAG antibodies
LT3415531T (lt) 2011-05-27 2023-09-25 Glaxo Group Limited Bcma (cd269/tnfrsf17) – surišantys baltymai
WO2014029752A1 (en) 2012-08-22 2014-02-27 Glaxo Group Limited Anti lrp6 antibodies
US10176293B2 (en) 2012-10-02 2019-01-08 Roche Molecular Systems, Inc. Universal method to determine real-time PCR cycle threshold values
SI2970464T1 (sl) 2013-03-15 2020-08-31 Glaxosmithkline Intellectual Propety Development Limited Anti-LAG-3 vezavni proteini
CA2917661C (en) * 2013-07-10 2023-09-12 Onconox Aps Antibodies to .beta.2-glycoprotein i and therapeutic uses thereof
US10556945B2 (en) 2014-03-21 2020-02-11 Teva Pharmaceuticals International Gmbh Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
US9896502B2 (en) 2014-03-21 2018-02-20 Teva Pharmaceuticals International Gmbh Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
KR20180042412A (ko) 2015-09-02 2018-04-25 이뮤텝 에스.에이.에스. 항-lag-3 항체
JP6935184B2 (ja) * 2016-05-31 2021-09-15 シスメックス株式会社 糖ペプチドと反応するモノクローナル抗体およびその用途
US10479827B2 (en) * 2016-05-31 2019-11-19 Sysmex Corporation Monoclonal antibody reacting with glycopeptide, and use thereof
AU2017281830B2 (en) 2016-06-20 2023-04-06 Kymab Limited Anti-PD-L1 antibodies
KR20190066607A (ko) 2016-09-23 2019-06-13 테바 파마슈티컬스 인터내셔널 게엠베하 불응성 편두통의 치료
AU2020308053A1 (en) 2019-06-26 2022-01-20 Glaxosmithkline Intellectual Property Development Limited IL1RAP binding proteins
CN112552403A (zh) * 2020-12-25 2021-03-26 南京英瀚斯生物科技有限公司 一种人源抗人CD23抗体的Fab片段、药物组合物及其应用

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DK0605442T3 (da) * 1991-07-25 2003-08-04 Idec Pharma Corp Rekombinante antistoffer til human terapi
MX9204374A (es) * 1991-07-25 1993-03-01 Idec Pharma Corp Anticuerpo recombinante y metodo para su produccion.
CA2203363A1 (en) * 1994-10-25 1996-05-02 Jean-Yves Marcel Paul Bonnefoy Binding agents to cd23
US6011138A (en) 1997-02-20 2000-01-04 Idec Pharmaceuticals Corporation Gamma-1 anti-human CD23 monoclonal antibodies

Also Published As

Publication number Publication date
WO1999058679A1 (en) 1999-11-18
AU3836799A (en) 1999-11-29
YU69000A (sh) 2003-08-29
CN1308676A (zh) 2001-08-15
EA200001041A1 (ru) 2001-06-25
EP1076701A1 (en) 2001-02-21
CA2328606A1 (en) 1999-11-18
KR20010043470A (ko) 2001-05-25
AP1547A (en) 2006-01-13
IS5696A (is) 2000-10-31
NZ507879A (en) 2004-02-27
EE200000658A (et) 2002-04-15
HUP0102005A2 (hu) 2001-10-28
GB9809839D0 (en) 1998-07-08
ID28088A (id) 2001-05-03
BR9910327A (pt) 2001-01-30
PL344019A1 (en) 2001-09-24
HRP20000762A2 (en) 2001-06-30
AP2000001983A0 (en) 2000-12-31
JP2002514421A (ja) 2002-05-21
US7008623B1 (en) 2006-03-07
IL139384A0 (en) 2001-11-25
NO20005632D0 (no) 2000-11-08
ZA200006312B (en) 2003-02-26
NO20005632L (no) 2001-01-08
HUP0102005A3 (en) 2003-10-28
AU763491B2 (en) 2003-07-24
SK16762000A3 (sk) 2001-07-10

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