PT877803E - Receptor da proteina ob e composicoes e metodos afins - Google Patents

Receptor da proteina ob e composicoes e metodos afins

Info

Publication number
PT877803E
PT877803E PT97901343T PT97901343T PT877803E PT 877803 E PT877803 E PT 877803E PT 97901343 T PT97901343 T PT 97901343T PT 97901343 T PT97901343 T PT 97901343T PT 877803 E PT877803 E PT 877803E
Authority
PT
Portugal
Prior art keywords
protein
compositions
receptor
nucleic acids
receptors
Prior art date
Application number
PT97901343T
Other languages
English (en)
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of PT877803E publication Critical patent/PT877803E/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Obesity (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Child & Adolescent Psychology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT97901343T 1996-01-04 1997-01-02 Receptor da proteina ob e composicoes e metodos afins PT877803E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58282596A 1996-01-04 1996-01-04
US77441496A 1996-12-31 1996-12-31

Publications (1)

Publication Number Publication Date
PT877803E true PT877803E (pt) 2005-11-30

Family

ID=27078678

Family Applications (1)

Application Number Title Priority Date Filing Date
PT97901343T PT877803E (pt) 1996-01-04 1997-01-02 Receptor da proteina ob e composicoes e metodos afins

Country Status (11)

Country Link
EP (1) EP0877803B1 (pt)
JP (1) JP2000502569A (pt)
AT (1) ATE303437T1 (pt)
AU (1) AU1526297A (pt)
DE (1) DE69734096T2 (pt)
DK (1) DK0877803T3 (pt)
ES (1) ES2244990T3 (pt)
IL (1) IL125081A (pt)
NZ (1) NZ534416A (pt)
PT (1) PT877803E (pt)
WO (1) WO1997025424A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001968A (en) 1994-08-17 1999-12-14 The Rockefeller University OB polypeptides, modified forms and compositions
US6977240B1 (en) 1995-11-27 2005-12-20 Millenium Pharmaceuticals, Inc. Methods of using the OB receptor antibodies to treat bodyweight disorders
US6482927B1 (en) * 1995-11-27 2002-11-19 Millennium Pharmaceuticals, Inc. Chimeric proteins comprising the extracellular domain of murine Ob receptor
US7074397B1 (en) 1996-01-08 2006-07-11 Genentech, Inc. Method for enhancing proliferation or differentiation of a cell using ob protein
US20050019325A1 (en) 1996-01-08 2005-01-27 Carter Paul J. WSX receptor agonist antibodies
US6541604B1 (en) 1996-01-08 2003-04-01 Genentech, Inc. Leptin receptor having a WSX motif
US7063958B1 (en) 1996-01-16 2006-06-20 The Rockefeller University Nucleic acids db, the receptor for leptin
AU2476301A (en) * 1996-01-16 2001-05-24 Rockefeller University, The DB the receptor for leptin nucleic acids encoding the receptor, and uses thereof
US7148004B1 (en) 1997-01-16 2006-12-12 The Rockefeller University Oligonucleotides of the OB-R isoforms and methods of diagnosing body weight
US7084252B1 (en) 1996-01-16 2006-08-01 The Rockefeller University DB, the receptor for leptin
US7619079B2 (en) 1996-02-14 2009-11-17 The Rockefeller University Db, the receptor for leptin, nucleic acids encoding the receptor, and uses thereof
EP0921820A4 (en) * 1996-06-20 2003-01-15 Merck & Co Inc GENE THERAPY OF OBESITY
AU7821798A (en) * 1997-06-09 1998-12-30 Regeneron Pharmaceuticals, Inc. Assay systems for leptin-enhancing agents
US20020192751A1 (en) 1998-05-15 2002-12-19 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US6770444B2 (en) 1998-07-16 2004-08-03 Synaptic Pharmaceutical Corporation Methods of identifying or screening for agents that binds the Ob-Re
FR2836475B1 (fr) * 2002-02-26 2007-02-23 Aventis Pharma Sa Procede de detection de ligands du recepteur de la leptine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643748A (en) * 1994-09-14 1997-07-01 Progenitor, Inc. HU-B1.219, a novel human hematopoietin receptor
US6482927B1 (en) * 1995-11-27 2002-11-19 Millennium Pharmaceuticals, Inc. Chimeric proteins comprising the extracellular domain of murine Ob receptor
US20020193571A1 (en) * 1996-01-08 2002-12-19 Paul J. Carter Wsx receptor agonist antibodies
US7063958B1 (en) * 1996-01-16 2006-06-20 The Rockefeller University Nucleic acids db, the receptor for leptin
EP1731164A1 (en) * 1996-01-23 2006-12-13 Indevus Pharmaceuticals, Inc. Methods for using the obese gene and its gene product to stimulate hematopoietic development

Also Published As

Publication number Publication date
IL125081A0 (en) 1999-01-26
WO1997025424A1 (en) 1997-07-17
DE69734096T2 (de) 2006-06-29
ES2244990T3 (es) 2005-12-16
DK0877803T3 (da) 2005-09-19
IL125081A (en) 2006-08-01
DE69734096D1 (de) 2005-10-06
EP0877803A1 (en) 1998-11-18
NZ534416A (en) 2005-12-23
AU1526297A (en) 1997-08-01
EP0877803B1 (en) 2005-08-31
ATE303437T1 (de) 2005-09-15
JP2000502569A (ja) 2000-03-07

Similar Documents

Publication Publication Date Title
PT877803E (pt) Receptor da proteina ob e composicoes e metodos afins
DE60119714D1 (de) Peptidderivat
IL124831A0 (en) Ob protein derivatives having prolonged half-life
DK0733067T3 (da) N-terminalt kemisk modificerede proteinpræparater og fremgangsmåder
ATE352618T1 (de) Rezeptor 5, der eine für den zelltod verantwortliche domäne enthält
BR9808881A (pt) Compostos para imunoterapia de câncer de próstata e métodos para seu uso
ATE277081T1 (de) Inhibitoren des humanplasmins, die sich von den kunitz domänen ableiten
DE60025832D1 (de) Mehrere zytokin-antikörper komplexen
IL123189A0 (en) Colon cell and colon cancer cell associated nucleic acid molecules protein and peptides
MXPA02008239A (es) Gen humano de la esquizofrenia.
MX9702789A (es) Novedosas proteinas ligandos del dominio de la muerte del receptor tnf, e inhibidores de la union delos ligandos.
ATE271394T1 (de) Hybride zusammensetzungen für intrazellulaire verabreichung
FI972170A (fi) Peptidejä, jotka kykenevät sitoutumaan GAP-proteiinin SH3-domeeniin, näitä peptidejä koodittavia nukleotidisekvenssejä, niiden valmistus ja käyttö
DE69734596D1 (de) "smoothened" proteine aus wirbeltieren
SE9602822D0 (sv) New receptor
ATE432349T1 (de) Modifizierte hämoglobinähnliche verbindungen und verfahren zu deren reinigung
WO1999042127A3 (en) Receptor derived peptides as modulators of receptor activity
ATE359263T1 (de) Substitutierte aminosaeuren als erythropoietin- mimetica
CA2240394A1 (en) Ob protein receptor and related compositions and methods
ATE401402T1 (de) Mit syndekan interagierende proteine und deren verwendung
ATE407944T1 (de) Mit trp-proteinen verwandtes protein mtr1 und dieses codierende dna-sequenz
SE9604439D0 (sv) New receptor
WO2000017363A3 (en) Interleukin-1 like molecule: interleukin-1-zeta; nucleic acids, polypeptides, antibodies, their uses
IT8921396A0 (it) Procedimento per la sintesi di peptidi preventivamente identificati come siti di interazione di proteine interagenti.