HRP20000762A2 - Antibodies to cd23, derivatives thereof, and their therapeutic uses - Google Patents
Antibodies to cd23, derivatives thereof, and their therapeutic uses Download PDFInfo
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- HRP20000762A2 HRP20000762A2 HR20000762A HRP20000762A HRP20000762A2 HR P20000762 A2 HRP20000762 A2 HR P20000762A2 HR 20000762 A HR20000762 A HR 20000762A HR P20000762 A HRP20000762 A HR P20000762A HR P20000762 A2 HRP20000762 A2 HR P20000762A2
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- 230000028327 secretion Effects 0.000 description 1
- 238000010187 selection method Methods 0.000 description 1
- 239000006152 selective media Substances 0.000 description 1
- 238000002741 site-directed mutagenesis Methods 0.000 description 1
- 239000001632 sodium acetate Substances 0.000 description 1
- 235000017281 sodium acetate Nutrition 0.000 description 1
- 239000001540 sodium lactate Substances 0.000 description 1
- 235000011088 sodium lactate Nutrition 0.000 description 1
- 229940005581 sodium lactate Drugs 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000010473 stable expression Effects 0.000 description 1
- 239000008223 sterile water Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 150000003431 steroids Chemical class 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000013595 supernatant sample Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 210000001179 synovial fluid Anatomy 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 229940002004 the magic bullet Drugs 0.000 description 1
- 229940104230 thymidine Drugs 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 102000027257 transmembrane receptors Human genes 0.000 description 1
- 108091008578 transmembrane receptors Proteins 0.000 description 1
- 229940046728 tumor necrosis factor alpha inhibitor Drugs 0.000 description 1
- 239000002451 tumor necrosis factor inhibitor Substances 0.000 description 1
- 102000003298 tumor necrosis factor receptor Human genes 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- DRTQHJPVMGBUCF-UHFFFAOYSA-N uracil arabinoside Natural products OC1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-UHFFFAOYSA-N 0.000 description 1
- 229940045145 uridine Drugs 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 239000004474 valine Substances 0.000 description 1
- 210000005253 yeast cell Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2851—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9809839.5A GB9809839D0 (en) | 1998-05-09 | 1998-05-09 | Antibody |
| PCT/GB1999/001434 WO1999058679A1 (en) | 1998-05-09 | 1999-05-07 | Antibodies to cd23, derivatives thereof, and their therapeutic uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20000762A2 true HRP20000762A2 (en) | 2001-06-30 |
Family
ID=10831668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20000762A HRP20000762A2 (en) | 1998-05-09 | 2000-11-09 | Antibodies to cd23, derivatives thereof, and their therapeutic uses |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7008623B1 (sh) |
| EP (1) | EP1076701A1 (sh) |
| JP (1) | JP2002514421A (sh) |
| KR (1) | KR20010043470A (sh) |
| CN (1) | CN1308676A (sh) |
| AP (1) | AP1547A (sh) |
| AU (1) | AU763491B2 (sh) |
| BR (1) | BR9910327A (sh) |
| CA (1) | CA2328606A1 (sh) |
| EA (1) | EA200001041A1 (sh) |
| EE (1) | EE200000658A (sh) |
| GB (1) | GB9809839D0 (sh) |
| HR (1) | HRP20000762A2 (sh) |
| HU (1) | HUP0102005A3 (sh) |
| ID (1) | ID28088A (sh) |
| IL (1) | IL139384A0 (sh) |
| IS (1) | IS5696A (sh) |
| NO (1) | NO20005632L (sh) |
| NZ (1) | NZ507879A (sh) |
| PL (1) | PL344019A1 (sh) |
| SK (1) | SK16762000A3 (sh) |
| TR (1) | TR200003281T2 (sh) |
| WO (1) | WO1999058679A1 (sh) |
| YU (1) | YU69000A (sh) |
| ZA (1) | ZA200006312B (sh) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6696550B2 (en) | 1998-07-23 | 2004-02-24 | Millennium Pharmaceuticals, Inc. | Humanized anti-CCR2 antibodies and methods of use therefor |
| GEP20063752B (en) | 2000-10-13 | 2006-02-27 | Biogen Inc | Humanized Anti-LT-Beta-R Antibodies |
| US20040151721A1 (en) | 2001-10-19 | 2004-08-05 | O'keefe Theresa | Humanized anti-CCR2 antibodies and methods of use therefor |
| WO2004002431A2 (en) * | 2002-07-01 | 2004-01-08 | Biogen, Inc. | Humanized anti-lymphotoyin beta receptor antibodies |
| AR040778A1 (es) | 2002-08-06 | 2005-04-20 | Glaxo Group Ltd | Anticuerpos alterados o fragmentos funcionales que se unen a mag (glicoproteina asociada a mielina). |
| GB0306309D0 (en) | 2003-03-19 | 2003-04-23 | Glaxo Group Ltd | Method of treatment |
| WO2005000898A2 (en) | 2003-06-27 | 2005-01-06 | Biogen Idec Ma Inc. | Use of hydrophobic-interaction-chromatography or hinge-region modifications for the production of homogeneous antibody-solutions |
| CA2434668A1 (en) | 2003-07-04 | 2005-01-04 | Laurence Mulard | Novel approach to design glycopeptides based on o-specific polysaccharide of shigella flexneri serotype 2a |
| EP1631311A4 (en) * | 2003-12-10 | 2007-04-11 | Millennium Pharm Inc | HUMANIZED ANTI-CCR2 ANTIBODIES AND METHOD OF USE |
| US7435799B2 (en) * | 2004-01-08 | 2008-10-14 | Applied Molecular Evolution | TNF-α binding molecules |
| CA2560742A1 (en) | 2004-03-23 | 2005-10-06 | Biogen Idec Ma Inc. | Receptor coupling agents and therapeutic uses thereof |
| US20060246075A1 (en) * | 2004-09-29 | 2006-11-02 | Marc Mercken | Anti-amyloid antibodies, compositions, methods and uses |
| WO2006074399A2 (en) | 2005-01-05 | 2006-07-13 | Biogen Idec Ma Inc. | Multispecific binding molecules comprising connecting peptides |
| CN101309704B (zh) | 2005-11-14 | 2012-10-10 | 礼纳特神经***科学公司 | 针对降钙素基因相关肽的拮抗剂抗体及其使用方法 |
| GB0525662D0 (en) | 2005-12-16 | 2006-01-25 | Glaxo Group Ltd | Immunoglobulins |
| US7680868B2 (en) * | 2005-12-20 | 2010-03-16 | Roche Molecular Systems, Inc. | PCR elbow determination by use of a double sigmoid function curve fit with the Levenburg-Marquardt algorithm and normalization |
| EP1804172B1 (en) * | 2005-12-20 | 2021-08-11 | Roche Diagnostics GmbH | PCR elbow determination using curvature analysis of a double sigmoid |
| WO2009043051A2 (en) * | 2007-09-27 | 2009-04-02 | Biogen Idec Ma Inc. | Cd23 binding molecules and methods of use thereof |
| US20090148905A1 (en) | 2007-11-30 | 2009-06-11 | Claire Ashman | Antigen-binding constructs |
| CA2716424C (en) | 2008-03-04 | 2015-04-28 | Pfizer Limited | Methods of treating chronic pain |
| EP2271323A2 (en) | 2008-05-06 | 2011-01-12 | Glaxo Group Limited | Encapsulation of biologically active agents |
| CA2753332A1 (en) | 2009-02-24 | 2010-09-02 | Glaxo Group Limited | Antigen-binding constructs |
| EP2401298A1 (en) | 2009-02-24 | 2012-01-04 | Glaxo Group Limited | Antigen-binding constructs |
| WO2010097394A1 (en) | 2009-02-24 | 2010-09-02 | Glaxo Group Limited | Multivalent and/or multispecific rankl-binding constructs |
| JP2012522749A (ja) | 2009-04-01 | 2012-09-27 | グラクソ グループ リミテッド | 抗ｉｌ−２３免疫グロブリン |
| WO2010122090A1 (en) | 2009-04-24 | 2010-10-28 | Glaxo Group Limited | Fgfr1c antibody combinations |
| AU2010288194B2 (en) | 2009-08-28 | 2013-08-29 | Teva Pharmaceuticals International Gmbh | Methods for treating visceral pain by administering antagonist antibodies directed against calcitonin gene-related peptide |
| FR2957598B1 (fr) * | 2010-03-17 | 2015-12-04 | Lfb Biotechnologies | Nouveau peptide signal, et son utilisation pour la production de proteines recombinantes |
| KR101947356B1 (ko) | 2010-11-23 | 2019-02-12 | 글락소 그룹 리미티드 | 온코스타틴 ｍ (ｏｓｍ)에 대한 항원 결합 단백질 |
| MX2013005847A (es) | 2010-11-24 | 2013-12-12 | Glaxo Group Ltd | Proteinas de union a antigeno multiespecificas que eligen como blanco a hgf. |
| US8974782B2 (en) | 2011-02-07 | 2015-03-10 | Glaxo Group Limited | Treatment of stroke comprising anti-MAG antibodies |
| LT3415531T (lt) | 2011-05-27 | 2023-09-25 | Glaxo Group Limited | Bcma (cd269/tnfrsf17) – surišantys baltymai |
| WO2014029752A1 (en) | 2012-08-22 | 2014-02-27 | Glaxo Group Limited | Anti lrp6 antibodies |
| US10176293B2 (en) | 2012-10-02 | 2019-01-08 | Roche Molecular Systems, Inc. | Universal method to determine real-time PCR cycle threshold values |
| SI2970464T1 (sl) | 2013-03-15 | 2020-08-31 | Glaxosmithkline Intellectual Propety Development Limited | Anti-LAG-3 vezavni proteini |
| CA2917661C (en) * | 2013-07-10 | 2023-09-12 | Onconox Aps | Antibodies to .beta.2-glycoprotein i and therapeutic uses thereof |
| US10556945B2 (en) | 2014-03-21 | 2020-02-11 | Teva Pharmaceuticals International Gmbh | Antagonist antibodies directed against calcitonin gene-related peptide and methods using same |
| US9896502B2 (en) | 2014-03-21 | 2018-02-20 | Teva Pharmaceuticals International Gmbh | Antagonist antibodies directed against calcitonin gene-related peptide and methods using same |
| KR20180042412A (ko) | 2015-09-02 | 2018-04-25 | 이뮤텝 에스.에이.에스. | 항-lag-3 항체 |
| JP6935184B2 (ja) * | 2016-05-31 | 2021-09-15 | シスメックス株式会社 | 糖ペプチドと反応するモノクローナル抗体およびその用途 |
| US10479827B2 (en) * | 2016-05-31 | 2019-11-19 | Sysmex Corporation | Monoclonal antibody reacting with glycopeptide, and use thereof |
| AU2017281830B2 (en) | 2016-06-20 | 2023-04-06 | Kymab Limited | Anti-PD-L1 antibodies |
| KR20190066607A (ko) | 2016-09-23 | 2019-06-13 | 테바 파마슈티컬스 인터내셔널 게엠베하 | 불응성 편두통의 치료 |
| AU2020308053A1 (en) | 2019-06-26 | 2022-01-20 | Glaxosmithkline Intellectual Property Development Limited | IL1RAP binding proteins |
| CN112552403A (zh) * | 2020-12-25 | 2021-03-26 | 南京英瀚斯生物科技有限公司 | 一种人源抗人CD23抗体的Fab片段、药物组合物及其应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0605442T3 (da) * | 1991-07-25 | 2003-08-04 | Idec Pharma Corp | Rekombinante antistoffer til human terapi |
| MX9204374A (es) * | 1991-07-25 | 1993-03-01 | Idec Pharma Corp | Anticuerpo recombinante y metodo para su produccion. |
| CA2203363A1 (en) * | 1994-10-25 | 1996-05-02 | Jean-Yves Marcel Paul Bonnefoy | Binding agents to cd23 |
| US6011138A (en) | 1997-02-20 | 2000-01-04 | Idec Pharmaceuticals Corporation | Gamma-1 anti-human CD23 monoclonal antibodies |
-
1998
- 1998-05-09 GB GBGB9809839.5A patent/GB9809839D0/en not_active Ceased
-
1999
- 1999-05-07 AP APAP/P/2000/001983A patent/AP1547A/en active
- 1999-05-07 PL PL99344019A patent/PL344019A1/xx unknown
- 1999-05-07 EE EEP200000658A patent/EE200000658A/xx unknown
- 1999-05-07 SK SK1676-2000A patent/SK16762000A3/sk unknown
- 1999-05-07 AU AU38367/99A patent/AU763491B2/en not_active Ceased
- 1999-05-07 US US09/674,716 patent/US7008623B1/en not_active Expired - Fee Related
- 1999-05-07 WO PCT/GB1999/001434 patent/WO1999058679A1/en not_active Application Discontinuation
- 1999-05-07 IL IL13938499A patent/IL139384A0/xx unknown
- 1999-05-07 NZ NZ507879A patent/NZ507879A/xx unknown
- 1999-05-07 BR BR9910327-3A patent/BR9910327A/pt not_active Application Discontinuation
- 1999-05-07 CN CN99808452A patent/CN1308676A/zh active Pending
- 1999-05-07 CA CA002328606A patent/CA2328606A1/en not_active Abandoned
- 1999-05-07 JP JP2000548470A patent/JP2002514421A/ja not_active Ceased
- 1999-05-07 ID IDW20002573A patent/ID28088A/id unknown
- 1999-05-07 EA EA200001041A patent/EA200001041A1/ru unknown
- 1999-05-07 TR TR2000/03281T patent/TR200003281T2/xx unknown
- 1999-05-07 HU HU0102005A patent/HUP0102005A3/hu unknown
- 1999-05-07 YU YU69000A patent/YU69000A/sh unknown
- 1999-05-07 KR KR1020007012530A patent/KR20010043470A/ko not_active Application Discontinuation
- 1999-05-07 EP EP99920991A patent/EP1076701A1/en not_active Withdrawn
-
2000
- 2000-10-31 IS IS5696A patent/IS5696A/is unknown
- 2000-11-03 ZA ZA200006312A patent/ZA200006312B/xx unknown
- 2000-11-08 NO NO20005632A patent/NO20005632L/no not_active Application Discontinuation
- 2000-11-09 HR HR20000762A patent/HRP20000762A2/hr not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999058679A1 (en) | 1999-11-18 |
| AU3836799A (en) | 1999-11-29 |
| YU69000A (sh) | 2003-08-29 |
| CN1308676A (zh) | 2001-08-15 |
| EA200001041A1 (ru) | 2001-06-25 |
| EP1076701A1 (en) | 2001-02-21 |
| CA2328606A1 (en) | 1999-11-18 |
| KR20010043470A (ko) | 2001-05-25 |
| AP1547A (en) | 2006-01-13 |
| IS5696A (is) | 2000-10-31 |
| NZ507879A (en) | 2004-02-27 |
| EE200000658A (et) | 2002-04-15 |
| HUP0102005A2 (hu) | 2001-10-28 |
| TR200003281T2 (tr) | 2001-03-21 |
| GB9809839D0 (en) | 1998-07-08 |
| ID28088A (id) | 2001-05-03 |
| BR9910327A (pt) | 2001-01-30 |
| PL344019A1 (en) | 2001-09-24 |
| AP2000001983A0 (en) | 2000-12-31 |
| JP2002514421A (ja) | 2002-05-21 |
| US7008623B1 (en) | 2006-03-07 |
| IL139384A0 (en) | 2001-11-25 |
| NO20005632D0 (no) | 2000-11-08 |
| ZA200006312B (en) | 2003-02-26 |
| NO20005632L (no) | 2001-01-08 |
| HUP0102005A3 (en) | 2003-10-28 |
| AU763491B2 (en) | 2003-07-24 |
| SK16762000A3 (sk) | 2001-07-10 |
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