SK281341B6 - Deriváty pyridónkarboxylovej kyseliny alebo jej farmaceuticky prijateľných solí, spôsob ich prípravy a farmakologické prostriedky ich obsahujúce - Google Patents

Deriváty pyridónkarboxylovej kyseliny alebo jej farmaceuticky prijateľných solí, spôsob ich prípravy a farmakologické prostriedky ich obsahujúce Download PDF

Info

Publication number: SK281341B6
Authority: SK; Slovakia
Prior art keywords: group; formula; halogen; pharmaceutically acceptable; hydrogen atom
Prior art date: 1994-06-14

Application number

SK1574-96A

Other languages

English (en)

Slovak (sk)

Other versions

SK157496A3 (en

Inventor

Kyoji Tomita

Katsumi Chiba

Shigeki Kashimoto

Koh-Ichiro Shibamori

Yasunori Tsuzuki

Original Assignee

Dainippon Pharmaceutical Co., Ltd.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-06-14

Filing date

1995-06-06

Publication date

2001-02-12

1995-06-06 Application filed by Dainippon Pharmaceutical Co., Ltd. filed Critical Dainippon Pharmaceutical Co., Ltd.

1997-08-06 Publication of SK157496A3 publication Critical patent/SK157496A3/sk

2001-02-12 Publication of SK281341B6 publication Critical patent/SK281341B6/sk

Links

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COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
229910052697 platinum Inorganic materials 0.000 description 1
229920001993 poloxamer 188 Polymers 0.000 description 1
239000000244 polyoxyethylene sorbitan monooleate Substances 0.000 description 1
235000010482 polyoxyethylene sorbitan monooleate Nutrition 0.000 description 1
229920000053 polysorbate 80 Polymers 0.000 description 1
229940068968 polysorbate 80 Drugs 0.000 description 1
239000011698 potassium fluoride Substances 0.000 description 1
235000003270 potassium fluoride Nutrition 0.000 description 1
WSHYKIAQCMIPTB-UHFFFAOYSA-M potassium;2-oxo-3-(3-oxo-1-phenylbutyl)chromen-4-olate Chemical compound [K+].[O-]C=1C2=CC=CC=C2OC(=O)C=1C(CC(=O)C)C1=CC=CC=C1 WSHYKIAQCMIPTB-UHFFFAOYSA-M 0.000 description 1
230000002335 preservative effect Effects 0.000 description 1
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UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
YPOXGDJGKBXRFP-UHFFFAOYSA-N pyrimidine-4-carboxylic acid Chemical compound OC(=O)C1=CC=NC=N1 YPOXGDJGKBXRFP-UHFFFAOYSA-N 0.000 description 1
SBMSLRMNBSMKQC-UHFFFAOYSA-N pyrrolidin-1-amine Chemical compound NN1CCCC1 SBMSLRMNBSMKQC-UHFFFAOYSA-N 0.000 description 1
NGXSWUFDCSEIOO-UHFFFAOYSA-N pyrrolidin-3-amine Chemical compound NC1CCNC1 NGXSWUFDCSEIOO-UHFFFAOYSA-N 0.000 description 1
238000001953 recrystallisation Methods 0.000 description 1
238000011160 research Methods 0.000 description 1
229910052709 silver Inorganic materials 0.000 description 1
239000004332 silver Substances 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
239000012419 sodium bis(2-methoxyethoxy)aluminum hydride Substances 0.000 description 1
239000012312 sodium hydride Substances 0.000 description 1
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235000010288 sodium nitrite Nutrition 0.000 description 1
AKHNMLFCWUSKQB-UHFFFAOYSA-L sodium thiosulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=S AKHNMLFCWUSKQB-UHFFFAOYSA-L 0.000 description 1
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208000024891 symptom Diseases 0.000 description 1
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GZDLAMUIGYXKLH-HZPDHXFCSA-N tert-butyl 2-[[(3r,4r)-1-benzyl-4-methoxypyrrolidin-3-yl]amino]acetate Chemical compound C1[C@@H](NCC(=O)OC(C)(C)C)[C@H](OC)CN1CC1=CC=CC=C1 GZDLAMUIGYXKLH-HZPDHXFCSA-N 0.000 description 1
125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
QRMKWVNXYORDRU-UKRRQHHQSA-N tert-butyl n-[(3s,4r)-1-benzyl-4-methylpyrrolidin-3-yl]carbamate Chemical compound C1[C@@H](NC(=O)OC(C)(C)C)[C@H](C)CN1CC1=CC=CC=C1 QRMKWVNXYORDRU-UKRRQHHQSA-N 0.000 description 1
239000012085 test solution Substances 0.000 description 1
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230000002936 tranquilizing effect Effects 0.000 description 1
ITMCEJHCFYSIIV-UHFFFAOYSA-N triflic acid Chemical compound OS(=O)(=O)C(F)(F)F ITMCEJHCFYSIIV-UHFFFAOYSA-N 0.000 description 1
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239000004474 valine Substances 0.000 description 1
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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

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Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Pyridine Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

SK1574-96A 1994-06-14 1995-06-06 Deriváty pyridónkarboxylovej kyseliny alebo jej farmaceuticky prijateľných solí, spôsob ich prípravy a farmakologické prostriedky ich obsahujúce SK281341B6 (sk)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
JP15657894		1994-06-14
JP19792194		1994-07-28
JP30691494		1994-11-15
JP33995694		1994-12-28
JP8170595		1995-03-13
PCT/JP1995/001110 WO1995034559A1 (fr)	1994-06-14	1995-06-06	Nouveau compose, son procede de production et agent antitumoral

Publications (2)

Publication Number	Publication Date
SK157496A3 SK157496A3 (en)	1997-08-06
SK281341B6 true SK281341B6 (sk)	2001-02-12

Family

ID=27524935

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK1574-96A SK281341B6 (sk)	1994-06-14	1995-06-06	Deriváty pyridónkarboxylovej kyseliny alebo jej farmaceuticky prijateľných solí, spôsob ich prípravy a farmakologické prostriedky ich obsahujúce

Country Status (27)

Country	Link
US (1)	US5817669A (cs)
EP (1)	EP0787726B1 (cs)
JP (1)	JP3391796B2 (cs)
KR (1)	KR100350921B1 (cs)
CN (1)	CN1053668C (cs)
AT (1)	ATE209645T1 (cs)
AU (1)	AU679859B2 (cs)
BR (1)	BR9508037A (cs)
CA (1)	CA2192824C (cs)
CZ (1)	CZ292631B6 (cs)
DE (1)	DE69524251T2 (cs)
DK (1)	DK0787726T3 (cs)
ES (1)	ES2163512T3 (cs)
FI (1)	FI112485B (cs)
HK (1)	HK1000495A1 (cs)
HU (1)	HU220072B (cs)
MX (1)	MX9606331A (cs)
NO (1)	NO307255B1 (cs)
NZ (1)	NZ287139A (cs)
PL (1)	PL181867B1 (cs)
PT (1)	PT787726E (cs)
RO (1)	RO117793B1 (cs)
RU (1)	RU2151770C1 (cs)
SI (1)	SI0787726T1 (cs)
SK (1)	SK281341B6 (cs)
TW (1)	TW319769B (cs)
WO (1)	WO1995034559A1 (cs)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1432711A1 (en) *	2001-09-26	2004-06-30	Bayer Corporation	1,6-naphthyridine derivatives as antidiabetics
US6802423B2 (en) *	2002-02-20	2004-10-12	Trans Global Foods, Inc.	Disposable food delivery apparatus
EP1610795A4 (en) *	2003-04-07	2007-10-24	Cylene Pharmaceuticals Inc	SUBSTITUTED 1,4-DIHYDRO-4-OXO-1,8-NAPHTHPYRIDINE HETEROCYCLIC ANALOGUES
AU2004272414B2 (en) *	2003-09-10	2009-05-28	Kyorin Pharmaceutical Co., Ltd.	7-(4-substituted 3- cyclopropylaminomethyl-1- pyrrolidinyl) quinolonecarboxylic acid derivative
DE10352979A1 (de) *	2003-11-13	2005-06-09	Merck Patent Gmbh	Pyridopyrimidinone
ATE451924T1 (de) *	2004-03-15	2010-01-15	Sunesis Pharmaceuticals Inc	Sns-595 und anwendungsverfahren
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1995
- 1995-06-06 CZ CZ19963643A patent/CZ292631B6/cs not_active IP Right Cessation
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- 1995-06-06 WO PCT/JP1995/001110 patent/WO1995034559A1/ja active IP Right Grant
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1996
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HUT75777A (en)	1997-05-28
US5817669A (en)	1998-10-06
JP3391796B2 (ja)	2003-03-31
DK0787726T3 (da)	2002-02-11
FI112485B (fi)	2003-12-15
EP0787726B1 (en)	2001-11-28
KR100350921B1 (ko)	2002-11-18
MX9606331A (es)	1997-03-29
AU2576795A (en)	1996-01-05
EP0787726A4 (cs)	1997-08-06
FI965020A (fi)	1996-12-16
SK157496A3 (en)	1997-08-06
NO965305L (no)	1997-02-04
CA2192824C (en)	2006-11-07
RO117793B1 (ro)	2002-07-30
RU2151770C1 (ru)	2000-06-27
SI0787726T1 (en)	2002-04-30
NZ287139A (en)	1997-07-27
DE69524251T2 (de)	2002-07-11
EP0787726A1 (en)	1997-08-06
HK1000495A1 (en)	2002-07-19
PL317726A1 (en)	1997-04-28
BR9508037A (pt)	1997-09-16
PL181867B1 (pl)	2001-09-28
DE69524251D1 (de)	2002-01-10
CA2192824A1 (en)	1995-12-21
WO1995034559A1 (fr)	1995-12-21
PT787726E (pt)	2002-04-29
CN1158614A (zh)	1997-09-03
NO307255B1 (no)	2000-03-06
TW319769B (cs)	1997-11-11
ES2163512T3 (es)	2002-02-01
FI965020A0 (fi)	1996-12-13
ATE209645T1 (de)	2001-12-15
CN1053668C (zh)	2000-06-21
CZ292631B6 (cs)	2003-11-12
AU679859B2 (en)	1997-07-10
HU220072B (hu)	2001-10-28
CZ364396A3 (en)	1997-06-11
HU9603455D0 (en)	1997-02-28
NO965305D0 (no)	1996-12-11

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