SI2455381T1 - Triazolopiridinova spojina in njeno delovanje kot zaviralec prolil-hidroksilaze in induktor produkcije eritropoietina - Google Patents

Triazolopiridinova spojina in njeno delovanje kot zaviralec prolil-hidroksilaze in induktor produkcije eritropoietina

Info

Publication number: SI2455381T1
Authority: SI; Slovenia
Prior art keywords: action; prolyl hydroxylase; hydroxylase inhibitor; erythropoietin production; production inducer
Prior art date: 2009-07-17

Application number

SI201030682T

Other languages

English (en)

Inventor

Ikuo Mitani

Yosuke Ogoshi

Takuya Matsui

Masahiro Yokota

Masakazu Terashita

Dai Motoda

Kazuhito Ueyama

Hiroyuki Abe

Takahiro Hotta

Takashi Ito

Original Assignee

Japan Tobacco Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-07-17

Filing date

2010-07-16

Publication date

2014-08-29

2010-07-16 Application filed by Japan Tobacco Inc. filed Critical Japan Tobacco Inc.

2014-08-29 Publication of SI2455381T1 publication Critical patent/SI2455381T1/sl

Links

102000003951 Erythropoietin Human genes 0.000 title 1
108090000394 Erythropoietin Proteins 0.000 title 1
229940078467 Prolyl hydroxylase inhibitor Drugs 0.000 title 1
-1 Triazolopyridine compound Chemical class 0.000 title 1
229940105423 erythropoietin Drugs 0.000 title 1
239000000411 inducer Substances 0.000 title 1
OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics

SI201030682T 2009-07-17 2010-07-16 Triazolopiridinova spojina in njeno delovanje kot zaviralec prolil-hidroksilaze in induktor produkcije eritropoietina SI2455381T1 (sl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP2009169565		2009-07-17
US27312709P	2009-07-30	2009-07-30
PCT/JP2010/062037 WO2011007856A1 (ja)	2009-07-17	2010-07-16	トリアゾロピリジン化合物、ならびにそのプロリル水酸化酵素阻害剤およびエリスロポエチン産生誘導剤としての作用
EP10799914.6A EP2455381B9 (en)	2009-07-17	2010-07-16	Triazolopyridine compound, and action thereof as prolyl hydroxylase inhibitor and erythropoietin production inducer

Publications (1)

Publication Number	Publication Date
SI2455381T1 true SI2455381T1 (sl)	2014-08-29

Family

ID=43449466

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SI201030682T SI2455381T1 (sl)	2009-07-17	2010-07-16	Triazolopiridinova spojina in njeno delovanje kot zaviralec prolil-hidroksilaze in induktor produkcije eritropoietina

Country Status (29)

Country	Link
US (3)	US8283465B2 (sl)
EP (3)	EP2746282A1 (sl)
JP (8)	JP5021797B2 (sl)
KR (4)	KR20230165366A (sl)
CN (1)	CN102471337B (sl)
AR (1)	AR077417A1 (sl)
AU (1)	AU2010271732B2 (sl)
BR (1)	BR112012001157A2 (sl)
CA (1)	CA2768505C (sl)
CO (1)	CO6430426A2 (sl)
DK (1)	DK2455381T5 (sl)
ES (1)	ES2477968T3 (sl)
HK (1)	HK1168346A1 (sl)
HR (1)	HRP20140705T1 (sl)
IL (1)	IL217541A (sl)
ME (1)	ME01858B (sl)
MX (1)	MX2012000766A (sl)
MY (1)	MY160814A (sl)
NZ (1)	NZ598242A (sl)
PE (1)	PE20120629A1 (sl)
PL (1)	PL2455381T3 (sl)
PT (1)	PT2455381E (sl)
RS (1)	RS53499B1 (sl)
RU (1)	RU2538963C2 (sl)
SG (1)	SG178049A1 (sl)
SI (1)	SI2455381T1 (sl)
SM (1)	SMT201500122B (sl)
TW (1)	TWI485150B (sl)
WO (1)	WO2011007856A1 (sl)

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MX2020003816A (es) *	2017-10-04	2020-08-13	Japan Tobacco Inc	Compuesto de heteroarilo con contenido de nitrogeno, y su uso farmaceutico.
CN107739378A (zh) *	2017-11-14	2018-02-27	杭州安道药业有限公司	吲哚嗪衍生物及其在医药上的应用
CA3106385A1 (en) *	2018-09-13	2020-03-19	Kissei Pharmaceutical Co., Ltd.	Imidazopyridinone compound
CN110105355B (zh) *	2019-05-24	2021-09-21	烟台大学	一种1,2,3-***-[1,5-a]并喹啉类化合物的制备方法
CA3169000A1 (en) *	2020-03-11	2021-09-16	Hideki Takeuchi	Crystal of imidazopyridinone compound or salt thereof
WO2021216530A1 (en)	2020-04-20	2021-10-28	Akebia Therapeutics, Inc.	Treatment of viral infections, of organ injury, and of related conditions using a hif prolyl hydroxylase inhibitor or a hif-alpha stabilizer
WO2022150623A1 (en)	2021-01-08	2022-07-14	Akebia Therapeutics, Inc.	Compounds and composition for the treatment of anemia
CN113387948B (zh) *	2021-02-06	2022-06-10	成都诺和晟泰生物科技有限公司	一种稠环杂芳基衍生物及其药物组合物和治疗方法及用途
TW202313072A (zh)	2021-05-27	2023-04-01	美商凱立克斯生物製藥股份有限公司	檸檬酸鐵之兒科調配物
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2010
- 2010-07-16 AU AU2010271732A patent/AU2010271732B2/en active Active
- 2010-07-16 SG SG2012003570A patent/SG178049A1/en unknown
- 2010-07-16 BR BR112012001157A patent/BR112012001157A2/pt not_active Application Discontinuation
- 2010-07-16 EP EP14160395.1A patent/EP2746282A1/en not_active Withdrawn
- 2010-07-16 PE PE2012000056A patent/PE20120629A1/es active IP Right Grant
- 2010-07-16 KR KR1020237040564A patent/KR20230165366A/ko not_active Application Discontinuation
- 2010-07-16 JP JP2010161144A patent/JP5021797B2/ja active Active
- 2010-07-16 ES ES10799914.6T patent/ES2477968T3/es active Active
- 2010-07-16 MY MYPI2012000223A patent/MY160814A/en unknown
- 2010-07-16 PL PL10799914T patent/PL2455381T3/pl unknown
- 2010-07-16 RS RSP20140406 patent/RS53499B1/en unknown
- 2010-07-16 WO PCT/JP2010/062037 patent/WO2011007856A1/ja active Application Filing
- 2010-07-16 US US12/837,679 patent/US8283465B2/en active Active
- 2010-07-16 EP EP19188636.5A patent/EP3594213A1/en not_active Withdrawn
- 2010-07-16 ME MEP-2014-82A patent/ME01858B/me unknown
- 2010-07-16 PT PT107999146T patent/PT2455381E/pt unknown
- 2010-07-16 KR KR1020127004258A patent/KR101706803B1/ko active IP Right Grant
- 2010-07-16 EP EP10799914.6A patent/EP2455381B9/en active Active
- 2010-07-16 CN CN201080032238.2A patent/CN102471337B/zh active Active
- 2010-07-16 NZ NZ598242A patent/NZ598242A/xx unknown
- 2010-07-16 RU RU2012105467/04A patent/RU2538963C2/ru active
- 2010-07-16 KR KR1020187010331A patent/KR20180042443A/ko active Application Filing
- 2010-07-16 AR ARP100102614A patent/AR077417A1/es active IP Right Grant
- 2010-07-16 MX MX2012000766A patent/MX2012000766A/es active IP Right Grant
- 2010-07-16 SI SI201030682T patent/SI2455381T1/sl unknown
- 2010-07-16 CA CA2768505A patent/CA2768505C/en active Active
- 2010-07-16 TW TW099123410A patent/TWI485150B/zh active
- 2010-07-16 DK DK10799914.6T patent/DK2455381T5/en active
- 2010-07-16 KR KR1020177003353A patent/KR101850661B1/ko active IP Right Grant
2012
- 2012-01-15 IL IL217541A patent/IL217541A/en active IP Right Grant
- 2012-01-31 CO CO12014916A patent/CO6430426A2/es active IP Right Grant
- 2012-04-26 JP JP2012101381A patent/JP2012144571A/ja not_active Ceased
- 2012-09-06 US US13/605,329 patent/US20130096155A1/en not_active Abandoned
- 2012-09-14 HK HK12109057.7A patent/HK1168346A1/xx unknown
2014
- 2014-07-22 HR HRP20140705AT patent/HRP20140705T1/hr unknown
- 2014-10-09 JP JP2014207896A patent/JP2015003933A/ja active Pending
2015
- 2015-05-22 SM SM201500122T patent/SMT201500122B/xx unknown
- 2015-06-25 US US14/749,966 patent/US20160145254A1/en not_active Abandoned
- 2015-12-08 JP JP2015239065A patent/JP2016040321A/ja active Pending
2017
- 2017-07-10 JP JP2017134270A patent/JP6434575B2/ja not_active Expired - Fee Related
2018
- 2018-11-08 JP JP2018210486A patent/JP2019019144A/ja active Pending
2020
- 2020-04-20 JP JP2020074508A patent/JP2020111612A/ja not_active Ceased
2022
- 2022-06-29 JP JP2022104161A patent/JP2022126843A/ja active Pending

Also Published As

Publication number	Publication date
HRP20140705T1 (hr)	2014-09-12
NZ598242A (en)	2013-09-27
JP2016040321A (ja)	2016-03-24
EP2455381A1 (en)	2012-05-23
CA2768505C (en)	2018-06-12
MX2012000766A (es)	2012-02-08
SMT201500122B (it)	2015-07-09
JP2012144571A (ja)	2012-08-02
HK1168346A1 (en)	2012-12-28
EP2746282A1 (en)	2014-06-25
MY160814A (en)	2017-03-31
ES2477968T9 (es)	2014-11-13
KR20230165366A (ko)	2023-12-05
CN102471337B (zh)	2014-12-10
JP2011037841A (ja)	2011-02-24
JP5021797B2 (ja)	2012-09-12
JP2015003933A (ja)	2015-01-08
RU2538963C2 (ru)	2015-01-10
US20130096155A1 (en)	2013-04-18
JP2022126843A (ja)	2022-08-30
EP2455381B1 (en)	2014-05-28
US8283465B2 (en)	2012-10-09
JP6434575B2 (ja)	2018-12-05
IL217541A (en)	2014-07-31
PE20120629A1 (es)	2012-05-30
RU2012105467A (ru)	2013-08-27
TWI485150B (zh)	2015-05-21
PT2455381E (pt)	2014-06-24
TW201105671A (en)	2011-02-16
KR20170018105A (ko)	2017-02-15
JP2019019144A (ja)	2019-02-07
PL2455381T3 (pl)	2014-10-31
AU2010271732B2 (en)	2016-08-25
EP3594213A1 (en)	2020-01-15
KR101850661B1 (ko)	2018-04-19
WO2011007856A1 (ja)	2011-01-20
DK2455381T3 (da)	2014-07-21
CA2768505A1 (en)	2011-01-20
KR20120051704A (ko)	2012-05-22
RS53499B1 (en)	2015-02-27
CO6430426A2 (es)	2012-04-30
ES2477968T3 (es)	2014-07-18
IL217541A0 (en)	2012-02-29
KR20180042443A (ko)	2018-04-25
AR077417A1 (es)	2011-08-24
JP2017214404A (ja)	2017-12-07
EP2455381A4 (en)	2012-12-12
US20160145254A1 (en)	2016-05-26
AU2010271732A1 (en)	2012-03-08
CN102471337A (zh)	2012-05-23
US20110077267A1 (en)	2011-03-31
ME01858B (me)	2014-12-20
JP2020111612A (ja)	2020-07-27
DK2455381T5 (en)	2015-02-09
BR112012001157A2 (pt)	2016-02-23
KR101706803B1 (ko)	2017-02-14
SG178049A1 (en)	2012-03-29
EP2455381B9 (en)	2014-10-22

Publication	Publication Date	Title
HK1168346A1 (en)	2012-12-28	Triazolopyridine compound, and action thereof as prolyl hydroxylase inhibitor and erythropoietin production inducer
HK1190334A1 (en)	2014-07-04	Prolyl hydroxylase inhibitors
HRP20141038T1 (en)	2014-12-05	Benzoimidazoles as prolyl hydroxylase inhibitors
IL230580B (en)	2019-07-31	Polymorphic forms of compounds as prolyl hydroxylase inhibitors and their uses
AU2012289429A8 (en)	2014-05-22	Polymorphic forms of compounds as prolyl hydroxylase inhibitor, and uses thereof
EP2326178A4 (en)	2012-10-24	INHIBITORS OF PROLYL-HYDROXYLASE
IL212762A0 (en)	2011-07-31	Thiochromene derivatives as hif hydroxylase inhibitors
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