SG11202002821UA - Salts of pyrrolotriazine derivatives useful as tam inhibitors - Google Patents

Salts of pyrrolotriazine derivatives useful as tam inhibitors

Info

Publication number
SG11202002821UA
SG11202002821UA SG11202002821UA SG11202002821UA SG11202002821UA SG 11202002821U A SG11202002821U A SG 11202002821UA SG 11202002821U A SG11202002821U A SG 11202002821UA SG 11202002821U A SG11202002821U A SG 11202002821UA SG 11202002821U A SG11202002821U A SG 11202002821UA
Authority
SG
Singapore
Prior art keywords
salts
derivatives useful
pyrrolotriazine derivatives
tam inhibitors
tam
Prior art date
Application number
SG11202002821UA
Other languages
English (en)
Inventor
Zhongjiang Jia
Yongzhong Wu
Yongchun Pan
Jiacheng Zhou
Qun Li
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of SG11202002821UA publication Critical patent/SG11202002821UA/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
SG11202002821UA 2017-09-27 2018-09-26 Salts of pyrrolotriazine derivatives useful as tam inhibitors SG11202002821UA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762564070P 2017-09-27 2017-09-27
US201862714196P 2018-08-03 2018-08-03
PCT/US2018/052925 WO2019067594A1 (en) 2017-09-27 2018-09-26 SALTS OF PYRROLOTRIAZINE DERIVATIVES USEFUL AS TAM INHIBITORS

Publications (1)

Publication Number Publication Date
SG11202002821UA true SG11202002821UA (en) 2020-04-29

Family

ID=63794769

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11202002821UA SG11202002821UA (en) 2017-09-27 2018-09-26 Salts of pyrrolotriazine derivatives useful as tam inhibitors

Country Status (32)

Country Link
US (3) US10633387B2 (zh)
EP (2) EP3988552A1 (zh)
JP (2) JP2020535168A (zh)
KR (1) KR20200088308A (zh)
CN (1) CN111386273A (zh)
AU (2) AU2018342471B2 (zh)
BR (1) BR112020006145A2 (zh)
CA (1) CA3077308A1 (zh)
CL (2) CL2020000791A1 (zh)
CO (1) CO2020005009A2 (zh)
CR (1) CR20200179A (zh)
CY (1) CY1124952T1 (zh)
DK (1) DK3687996T3 (zh)
EC (1) ECSP20021655A (zh)
ES (1) ES2904458T3 (zh)
GE (1) GEP20227429B (zh)
HU (1) HUE057190T2 (zh)
IL (1) IL273579A (zh)
JO (1) JOP20200081A1 (zh)
LT (1) LT3687996T (zh)
MA (1) MA50655B1 (zh)
MD (1) MD3687996T2 (zh)
MX (1) MX2020003375A (zh)
PE (1) PE20210002A1 (zh)
PH (1) PH12020550143A1 (zh)
PL (1) PL3687996T3 (zh)
PT (1) PT3687996T (zh)
RS (1) RS62872B1 (zh)
SG (1) SG11202002821UA (zh)
SI (1) SI3687996T1 (zh)
TW (1) TWI821200B (zh)
WO (1) WO2019067594A1 (zh)

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KR20210039432A (ko) 2018-08-03 2021-04-09 카덴트 테라퓨틱스, 인크. 헤테로방향족 nmda 수용체 조절제 및 이의 용도
CN115697343A (zh) 2020-03-06 2023-02-03 因赛特公司 包含axl/mer和pd-1/pd-l1抑制剂的组合疗法
CN113912628B (zh) * 2020-07-10 2023-05-02 北京范恩柯尔生物科技有限公司 三嗪类化合物及其组合物和用途
CN115028648A (zh) * 2021-03-03 2022-09-09 武汉誉祥医药科技有限公司 三并环化合物及其药物组合物和应用
JPWO2023286719A1 (zh) * 2021-07-13 2023-01-19

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JP2020535168A (ja) 2020-12-03
US20190112313A1 (en) 2019-04-18
MA50655A (fr) 2021-06-02
DK3687996T3 (da) 2022-01-10
CA3077308A1 (en) 2019-04-04
TWI821200B (zh) 2023-11-11
AU2018342471B2 (en) 2023-08-24
EP3988552A1 (en) 2022-04-27
ES2904458T3 (es) 2022-04-05
PE20210002A1 (es) 2021-01-05
HUE057190T2 (hu) 2022-04-28
CO2020005009A2 (es) 2020-05-29
WO2019067594A1 (en) 2019-04-04
TW201920186A (zh) 2019-06-01
SI3687996T1 (sl) 2022-04-29
GEP20227429B (en) 2022-10-25
MX2020003375A (es) 2020-08-03
BR112020006145A2 (pt) 2020-10-20
US11104682B2 (en) 2021-08-31
AU2023270198A1 (en) 2023-12-14
US20200347065A1 (en) 2020-11-05
AU2018342471A1 (en) 2020-04-23
JOP20200081A1 (ar) 2020-04-30
MD3687996T2 (ro) 2022-04-30
EP3687996A1 (en) 2020-08-05
JP2024059647A (ja) 2024-05-01
EP3687996B1 (en) 2021-11-03
CN111386273A (zh) 2020-07-07
US20220227770A1 (en) 2022-07-21
PH12020550143A1 (en) 2020-12-07
LT3687996T (lt) 2022-01-10
ECSP20021655A (es) 2020-07-31
PT3687996T (pt) 2022-01-21
CR20200179A (es) 2020-11-02
KR20200088308A (ko) 2020-07-22
US10633387B2 (en) 2020-04-28
IL273579A (en) 2020-05-31
CY1124952T1 (el) 2023-01-05
CL2022001014A1 (es) 2022-11-18
CL2020000791A1 (es) 2020-09-25
PL3687996T3 (pl) 2022-02-21
MA50655B1 (fr) 2021-11-30
RS62872B1 (sr) 2022-02-28

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