SE9904723D0 - New modulators of dopamine neurotransmission II - Google Patents

New modulators of dopamine neurotransmission II

Info

Publication number
SE9904723D0
SE9904723D0 SE9904723A SE9904723A SE9904723D0 SE 9904723 D0 SE9904723 D0 SE 9904723D0 SE 9904723 A SE9904723 A SE 9904723A SE 9904723 A SE9904723 A SE 9904723A SE 9904723 D0 SE9904723 D0 SE 9904723D0
Authority
SE
Sweden
Prior art keywords
alkyl
furane
tetrahydrofurane
thiophene
disclosed
Prior art date
Application number
SE9904723A
Other languages
English (en)
Inventor
Claes Sonesson
Bengt Andersson
Susanna Waters
Nicholas Waters
Joakim Tedroff
Original Assignee
Carlsson A Research Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlsson A Research Ab filed Critical Carlsson A Research Ab
Priority to SE9904723A priority Critical patent/SE9904723D0/sv
Publication of SE9904723D0 publication Critical patent/SE9904723D0/sv
Priority to PCT/SE2000/002675 priority patent/WO2001046146A1/en
Priority to EEP200200345A priority patent/EE05083B1/xx
Priority to BR0016635-9A priority patent/BR0016635A/pt
Priority to PT03027034T priority patent/PT1419773E/pt
Priority to EP03027034A priority patent/EP1419773B1/en
Priority to CA002394606A priority patent/CA2394606C/en
Priority to HU0203874A priority patent/HUP0203874A3/hu
Priority to AU25706/01A priority patent/AU778183B2/en
Priority to MXPA02006317A priority patent/MXPA02006317A/es
Priority to NZ519566A priority patent/NZ519566A/en
Priority to SK866-2002A priority patent/SK287366B6/sk
Priority to DK03027034T priority patent/DK1419773T3/da
Priority to KR1020027008066A priority patent/KR100771287B1/ko
Priority to IL15035000A priority patent/IL150350A0/xx
Priority to NZ531643A priority patent/NZ531643A/en
Priority to DE60039131T priority patent/DE60039131D1/de
Priority to JP2001547057A priority patent/JP5096654B2/ja
Priority to CNB008182582A priority patent/CN1196680C/zh
Priority to US11/904,013 priority patent/USRE41315E1/en
Priority to PL362251A priority patent/PL205092B1/pl
Priority to US10/168,019 priority patent/US6924374B2/en
Priority to UA2002076054A priority patent/UA73337C2/uk
Priority to ES03027034T priority patent/ES2307861T3/es
Priority to AT03027034T priority patent/ATE397446T1/de
Priority to EP00989163A priority patent/EP1240143A1/en
Priority to CZ20022074A priority patent/CZ302907B6/cs
Priority to RU2002119417/04A priority patent/RU2262504C2/ru
Priority to ZA200204813A priority patent/ZA200204813B/xx
Priority to NO20022879A priority patent/NO323329B1/no
Priority to BG106845A priority patent/BG65698B1/bg
Priority to IL150350A priority patent/IL150350A/en
Priority to HR20020539A priority patent/HRP20020539B1/xx
Priority to HK03106410.6A priority patent/HK1054228B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
SE9904723A 1999-12-22 1999-12-22 New modulators of dopamine neurotransmission II SE9904723D0 (sv)

Priority Applications (34)

Application Number Priority Date Filing Date Title
SE9904723A SE9904723D0 (sv) 1999-12-22 1999-12-22 New modulators of dopamine neurotransmission II
RU2002119417/04A RU2262504C2 (ru) 1999-12-22 2000-12-22 Замещенные 4-(фенил-n-алкил)пиперидины, фармацевтическая композиция на их основе и способы лечения
DE60039131T DE60039131D1 (de) 1999-12-22 2000-12-22 4-Phenylpiperidin-Derivate als Modulatoren der Dopamin-Neurotransmission
CNB008182582A CN1196680C (zh) 1999-12-22 2000-12-22 新的多巴胺神经传递调节剂
BR0016635-9A BR0016635A (pt) 1999-12-22 2000-12-22 Moduladores de neurotransmissão de dopamina
JP2001547057A JP5096654B2 (ja) 1999-12-22 2000-12-22 ドーパミン神経伝達の新規のモジュレーター
EP03027034A EP1419773B1 (en) 1999-12-22 2000-12-22 4-Phenylpiperidine derivatives as modulators of dopamine neurotransmission
CA002394606A CA2394606C (en) 1999-12-22 2000-12-22 New modulators of dopamine neurotransmission
HU0203874A HUP0203874A3 (en) 1999-12-22 2000-12-22 Substituted 4-(phenyl-n-alkyl)-piperazine and piperidine derivatives and their use modulators of dopamine neutransmission and pharmaceutical compositions as containing them
EEP200200345A EE05083B1 (et) 1999-12-22 2000-12-22 Dopamiini neurotransmissiooni modulaatorid, nendekasutamine ja neid hendeid sisaldavad farmatseutilised kompositsioonid
MXPA02006317A MXPA02006317A (es) 1999-12-22 2000-12-22 Nuevos moduladores de neurotransmision de dopamina.
NZ519566A NZ519566A (en) 1999-12-22 2000-12-22 3-Substituted 4-phenyl-piperazine or piperidine derivatives useful as modulators of dopamine neurotransmission
SK866-2002A SK287366B6 (sk) 1999-12-22 2000-12-22 Modulátory neurotransmisie dopamínu
DK03027034T DK1419773T3 (da) 1999-12-22 2000-12-22 4-Phenylpiperidinderivativer som modulatorer af dopaminneurotransmission
KR1020027008066A KR100771287B1 (ko) 1999-12-22 2000-12-22 도파민 신경전달 조절제
US11/904,013 USRE41315E1 (en) 1999-12-22 2000-12-22 Modulators of dopamine neurotransmission
NZ531643A NZ531643A (en) 1999-12-22 2000-12-22 3-Substituted 4-phenyl-piperazine or piperidine derivatives useful as modulators of dopamine neurotransmission
PCT/SE2000/002675 WO2001046146A1 (en) 1999-12-22 2000-12-22 New modulators of dopamine neurotransmission
PT03027034T PT1419773E (pt) 1999-12-22 2000-12-22 Derivados de 4-fenilpiperidina como moduladores da neurotransmissão de dopamina
AU25706/01A AU778183B2 (en) 1999-12-22 2000-12-22 New modulators of dopamine neurotransmission
IL15035000A IL150350A0 (en) 1999-12-22 2000-12-22 New modulators of dopamine neurotransmission
PL362251A PL205092B1 (pl) 1999-12-22 2000-12-22 Podstawione 4-(fenylo-N-alkilo)piperydyny, zawierające je kompozycje farmaceutyczne i ich zastosowanie
US10/168,019 US6924374B2 (en) 1999-12-22 2000-12-22 Modulators of dopamine neurotransmission
UA2002076054A UA73337C2 (en) 1999-12-22 2000-12-22 Dopamine neurotransmission modulators
ES03027034T ES2307861T3 (es) 1999-12-22 2000-12-22 Derivados de 4-fenilpiperidina como moduladores de la neurotransmision de dopamina.
AT03027034T ATE397446T1 (de) 1999-12-22 2000-12-22 4-phenylpiperidin-derivate als modulatoren der dopamin-neurotransmission
EP00989163A EP1240143A1 (en) 1999-12-22 2000-12-22 New modulators of dopamine neurotransmission
CZ20022074A CZ302907B6 (cs) 1999-12-22 2000-12-22 Substituovaná (4-fenyl-N-alkyl)piperidinová sloucenina, její použití a farmaceutická kompozice s jejím obsahem
ZA200204813A ZA200204813B (en) 1999-12-22 2002-06-14 New modulators of dopamine neurotransmission.
NO20022879A NO323329B1 (no) 1999-12-22 2002-06-17 Substituerte 4-(fenyl-N-alkyl)-piperidin-forbindelser samt farmasoytiske materialer og anvendelser derav
BG106845A BG65698B1 (bg) 1999-12-22 2002-06-19 Заместени 4-(фенил-n-алкил)-пиперидинови съединения, фармацевтичен състав и използването им в медицината
IL150350A IL150350A (en) 1999-12-22 2002-06-20 New modulators of dopamine neurotransmission
HR20020539A HRP20020539B1 (en) 1999-12-22 2002-06-20 New modulators of dopamine neurotransmission
HK03106410.6A HK1054228B (zh) 1999-12-22 2003-09-09 新的多巴胺神經傳遞調節劑

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9904723A SE9904723D0 (sv) 1999-12-22 1999-12-22 New modulators of dopamine neurotransmission II

Publications (1)

Publication Number Publication Date
SE9904723D0 true SE9904723D0 (sv) 1999-12-22

Family

ID=20418252

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9904723A SE9904723D0 (sv) 1999-12-22 1999-12-22 New modulators of dopamine neurotransmission II

Country Status (30)

Country Link
US (2) USRE41315E1 (sv)
EP (2) EP1240143A1 (sv)
JP (1) JP5096654B2 (sv)
KR (1) KR100771287B1 (sv)
CN (1) CN1196680C (sv)
AT (1) ATE397446T1 (sv)
AU (1) AU778183B2 (sv)
BG (1) BG65698B1 (sv)
BR (1) BR0016635A (sv)
CA (1) CA2394606C (sv)
CZ (1) CZ302907B6 (sv)
DE (1) DE60039131D1 (sv)
DK (1) DK1419773T3 (sv)
EE (1) EE05083B1 (sv)
ES (1) ES2307861T3 (sv)
HK (1) HK1054228B (sv)
HR (1) HRP20020539B1 (sv)
HU (1) HUP0203874A3 (sv)
IL (2) IL150350A0 (sv)
MX (1) MXPA02006317A (sv)
NO (1) NO323329B1 (sv)
NZ (2) NZ519566A (sv)
PL (1) PL205092B1 (sv)
PT (1) PT1419773E (sv)
RU (1) RU2262504C2 (sv)
SE (1) SE9904723D0 (sv)
SK (1) SK287366B6 (sv)
UA (1) UA73337C2 (sv)
WO (1) WO2001046146A1 (sv)
ZA (1) ZA200204813B (sv)

Families Citing this family (29)

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SE9904724D0 (sv) * 1999-12-22 1999-12-22 Carlsson A Research Ab New modulators of dopamine neurotransmission I
USRE46117E1 (en) 1999-12-22 2016-08-23 Teva Pharmaceuticals International Gmbh Modulators of dopamine neurotransmission
SE9904723D0 (sv) 1999-12-22 1999-12-22 Carlsson A Research Ab New modulators of dopamine neurotransmission II
EP1638939A2 (en) * 2003-06-24 2006-03-29 Neurosearch A/S Aza-ring derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
DE10361259A1 (de) * 2003-12-24 2005-07-28 Schwarz Pharma Ag Verwendung von Rotigotine in einem Frühstadium von Morbus Parkinson zur Prävention des weiteren Neuronenverlustes
US7851629B2 (en) 2004-06-08 2010-12-14 Nsab, Filial Af Neurosearch Sweden Ab, Sverige Disubstituted phenylpiperidines as modulators of dopamine and serotonin neurotransmission
SE0401464D0 (sv) * 2004-06-08 2004-06-08 Carlsson A Research Ab New disubstituted phenylpiperidines/piperazines as modulators of dopamine neurotransmission
MXPA06013944A (es) * 2004-06-08 2007-10-08 Neurosearch Sweden Ab Nuevas fenilpiperidinas/piperazinas disustituidas como moduladores de la neurotransmision de dopamina.
SE0401465D0 (sv) 2004-06-08 2004-06-08 Carlsson A Research Ab New substituted piperdines as modulators of dopamine neurotransmission
JP2008501748A (ja) * 2004-06-08 2008-01-24 ニューロサーチ スウェーデン アクチボラゲット ドーパミン神経伝達のモジュレーターとしての新規な置換されたピペリジン
CA2569840C (en) 2004-06-08 2012-04-17 A. Carlsson Research Ab New disubstituted phenylpiperidines/piperazines as modulators of dopamine neurotransmission
CA2570064A1 (en) * 2004-06-18 2005-12-29 Neurosearch A/S Novel alkyl substituted piperazine derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
NZ555094A (en) 2004-10-13 2009-07-31 Nsab Af Neurosearch Sweden Ab Process for the synthesis of 4-(3-methanesulfonylphenyl)-1-n-propyl-piperidine
MX2007004216A (es) * 2004-10-13 2007-10-10 Neurosearch Sweden Ab Proceso para la sintesis de 4-(3-sulfonil)-piperidinas.
ITMI20051193A1 (it) * 2005-06-24 2006-12-25 Acraf Uso farmaceutico di una 1-3-clorofenil-3-alchilpiperazina
SE529246C2 (sv) * 2005-10-13 2007-06-12 Neurosearch Sweden Ab Nya disubstituerade fenyl-piperidiner som modulatorer för dopaminneurotransmission
EP1963268B1 (en) 2005-12-07 2010-12-01 NSAB, Filial af NeuroSearch Sweden AB, Sverige Disubstituted phenylpiperidines as modulators of cortical catecholaminergic neurotransmission
EP2146961B1 (en) * 2007-04-12 2014-01-29 IVAX International GmbH N-oxide and/or di-n-oxide derivatives of dopamine receptor stabilizers/modulators displaying improved cardiovascular side-effects profiles
MX2009012787A (es) 2007-06-05 2009-12-15 Nsab Af Neurosearch Sweden Ab Nuevas fenilpirrolidinas disustituidas como moduladores de neurotransmision catecolaminergica cortical.
CN101711234A (zh) 2007-06-05 2010-05-19 Nsab神经研究瑞典公司分公司 作为皮层儿茶酚胺能神经传递调节剂的新型二取代的苯基吡咯烷
CN102036976B (zh) * 2008-04-29 2013-05-01 Nsab神经研究瑞典公司分公司 多巴胺神经传递的调节剂
US20110105462A1 (en) * 2008-04-29 2011-05-05 Nsab, Filial Af Neurosearch Sweden Ab, Sverige Modulators of dopamine neurotransmission
AU2009242095A1 (en) * 2008-04-29 2009-11-05 Nsab, Filial Af Neurosearch Sweden Ab, Sverige Modulators of dopamine neurotransmission
WO2011107583A1 (en) 2010-03-04 2011-09-09 Nsab, Filial Af Neurosearch Sweden Ab, Sverige Substituted 4-phenyl-n-alkyl-piperidines for preventing onset or slowing progression of neurodegenerative disorders
WO2012028635A1 (en) 2010-09-03 2012-03-08 Nsab, Filial Af Neurosearch Sweden Ab, Sverige Deuterated analogs of pridopidine useful as dopaminergic stabilizers
AU2012306386B2 (en) 2011-09-07 2017-06-15 Teva Pharmaceuticals International Gmbh Polymorphic form of pridopidine hydrochloride
EP2787997A4 (en) 2011-12-08 2015-05-27 Ivax Int Gmbh HYDROBROMIDE SALT OF PRIDOPIDINE
EA027748B1 (ru) 2012-04-04 2017-08-31 Тева Фармасьютикалз Интернэшнл Гмбх Применение придопидина в комбинации с тетрабеназином для лечения двигательных нарушений и ожирения
AR105434A1 (es) 2015-07-22 2017-10-04 Teva Pharmaceuticals Int Gmbh Proceso para preparar pridopidina

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