SE437514B - N-/3-dimetylamino-2-(4-pyridinyl)-2-propenyliden/-n-metylmetaniminiumsalt, sett att framstella detta och kardioton komposition for okning av hjertkontraktiliteten - Google Patents
N-/3-dimetylamino-2-(4-pyridinyl)-2-propenyliden/-n-metylmetaniminiumsalt, sett att framstella detta och kardioton komposition for okning av hjertkontraktilitetenInfo
- Publication number
- SE437514B SE437514B SE8101205A SE8101205A SE437514B SE 437514 B SE437514 B SE 437514B SE 8101205 A SE8101205 A SE 8101205A SE 8101205 A SE8101205 A SE 8101205A SE 437514 B SE437514 B SE 437514B
- Authority
- SE
- Sweden
- Prior art keywords
- pyridinyl
- salt
- dimethylamino
- propenylidene
- acid addition
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/124,808 US4264609A (en) | 1980-02-26 | 1980-02-26 | N-[3-Dimethylamino-2-(4-pyridinyl)-2-propenylidene]-N-methylmethaniminium chloride hydrochloride, its use in preparing 5-(cyano or carbamyl)-[3,4'-bipyridin]-6(1H)-one and its use as a cardiotonic |
Publications (2)
Publication Number | Publication Date |
---|---|
SE8101205L SE8101205L (sv) | 1981-08-27 |
SE437514B true SE437514B (sv) | 1985-03-04 |
Family
ID=22416880
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8101205A SE437514B (sv) | 1980-02-26 | 1981-02-24 | N-/3-dimetylamino-2-(4-pyridinyl)-2-propenyliden/-n-metylmetaniminiumsalt, sett att framstella detta och kardioton komposition for okning av hjertkontraktiliteten |
SE8402727A SE452764B (sv) | 1980-02-26 | 1984-05-21 | Forfarande for framstellning av 5-(cyano eller karbamyl)-(3,4-bipyridin)-6(1h)-on |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8402727A SE452764B (sv) | 1980-02-26 | 1984-05-21 | Forfarande for framstellning av 5-(cyano eller karbamyl)-(3,4-bipyridin)-6(1h)-on |
Country Status (28)
Country | Link |
---|---|
US (1) | US4264609A (fr) |
JP (1) | JPS56128758A (fr) |
KR (2) | KR840002067B1 (fr) |
AR (1) | AR230630A1 (fr) |
AT (2) | AT380237B (fr) |
AU (1) | AU541644B2 (fr) |
BE (1) | BE887663A (fr) |
CA (1) | CA1128523A (fr) |
CH (1) | CH647509A5 (fr) |
DE (1) | DE3107306A1 (fr) |
DK (1) | DK171253B1 (fr) |
ES (1) | ES499776A1 (fr) |
FI (1) | FI76787C (fr) |
FR (1) | FR2476646A1 (fr) |
GB (1) | GB2070600B (fr) |
HK (1) | HK71789A (fr) |
IE (1) | IE51696B1 (fr) |
IL (1) | IL62161A (fr) |
IT (1) | IT1210992B (fr) |
LU (1) | LU83169A1 (fr) |
MX (1) | MX6908E (fr) |
NL (1) | NL192109C (fr) |
NO (1) | NO156689C (fr) |
NZ (1) | NZ196282A (fr) |
PH (2) | PH19904A (fr) |
PT (1) | PT72573B (fr) |
SE (2) | SE437514B (fr) |
ZA (1) | ZA811124B (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE77817T1 (de) | 1985-04-30 | 1992-07-15 | Dresden Arzneimittel | 3-cyan-pyridine, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung. |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4072746A (en) * | 1975-10-14 | 1978-02-07 | Sterling Drug Inc. | 3-Amino-5-(pyridinyl)-2(1H)-pyridinones |
US4004012A (en) * | 1975-10-14 | 1977-01-18 | Sterling Drug Inc. | 3-Cyano-5-(pyridinyl)-2(1H)-pyridinones |
-
1980
- 1980-02-26 US US06/124,808 patent/US4264609A/en not_active Expired - Lifetime
-
1981
- 1981-02-17 NZ NZ196282A patent/NZ196282A/xx unknown
- 1981-02-18 IL IL62161A patent/IL62161A/xx not_active IP Right Cessation
- 1981-02-20 GB GB8105369A patent/GB2070600B/en not_active Expired
- 1981-02-20 ZA ZA00811124A patent/ZA811124B/xx unknown
- 1981-02-20 AU AU67487/81A patent/AU541644B2/en not_active Expired
- 1981-02-24 CH CH1222/81A patent/CH647509A5/fr not_active IP Right Cessation
- 1981-02-24 SE SE8101205A patent/SE437514B/sv not_active IP Right Cessation
- 1981-02-24 FR FR8103609A patent/FR2476646A1/fr active Granted
- 1981-02-24 IT IT8119952A patent/IT1210992B/it active
- 1981-02-24 PH PH25258A patent/PH19904A/en unknown
- 1981-02-25 AT AT0088581A patent/AT380237B/de not_active IP Right Cessation
- 1981-02-25 PT PT72573A patent/PT72573B/pt unknown
- 1981-02-25 BE BE1/10150A patent/BE887663A/fr not_active IP Right Cessation
- 1981-02-25 KR KR1019810000616A patent/KR840002067B1/ko active
- 1981-02-25 NO NO810639A patent/NO156689C/no unknown
- 1981-02-25 CA CA371,690A patent/CA1128523A/fr not_active Expired
- 1981-02-25 IE IE397/81A patent/IE51696B1/en not_active IP Right Cessation
- 1981-02-25 ES ES499776A patent/ES499776A1/es not_active Expired
- 1981-02-25 FI FI810582A patent/FI76787C/fi not_active IP Right Cessation
- 1981-02-25 DK DK083981A patent/DK171253B1/da not_active IP Right Cessation
- 1981-02-25 NL NL8100922A patent/NL192109C/nl not_active IP Right Cessation
- 1981-02-25 MX MX819321U patent/MX6908E/es unknown
- 1981-02-26 LU LU83169A patent/LU83169A1/fr unknown
- 1981-02-26 DE DE19813107306 patent/DE3107306A1/de active Granted
- 1981-02-26 JP JP2759981A patent/JPS56128758A/ja active Granted
- 1981-02-26 AR AR284447A patent/AR230630A1/es active
-
1982
- 1982-03-01 PH PH26927A patent/PH17145A/en unknown
-
1983
- 1983-08-26 AT AT0305683A patent/AT380236B/de not_active IP Right Cessation
-
1984
- 1984-05-21 SE SE8402727A patent/SE452764B/sv not_active IP Right Cessation
- 1984-08-22 KR KR1019840005058A patent/KR840002066B1/ko not_active IP Right Cessation
-
1989
- 1989-09-07 HK HK717/89A patent/HK71789A/xx not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IE43956B1 (en) | Pyridinyl-2n1h)-pyridinones and preparation | |
NL8201999A (nl) | Gesubstitueerde 1,2-diaminocyclobuteen-3,4-dionen, werkwijze voor het bereiden daarvan; geneesmiddelen; werkwijze voor het behandelen van door bemiddeling van histamine h2-receptoren tot stand gekomen toestanden. | |
EP0350448A1 (fr) | Composés biaryles | |
EP1222171B1 (fr) | Nouveaux composes utiles pour traiter les complications vasculaires liees a l'age et au diabete, procede de preparation et utilisations therapeutiques de ces composes | |
US4298609A (en) | 4,5-Dihydro-6-(4-pyridinyl)-3-pyridazinol and salts, their preparation and use as blood pressure lowering agents | |
US4271168A (en) | Selected 3-acylamino-5-[4(or 3)-pyridinyl]-2(1H)-pyridinones | |
SE437514B (sv) | N-/3-dimetylamino-2-(4-pyridinyl)-2-propenyliden/-n-metylmetaniminiumsalt, sett att framstella detta och kardioton komposition for okning av hjertkontraktiliteten | |
NO851113L (no) | ((pyridinyl)-2-pyrimidinyl)ureaforbindelser egnet som kardiotoniske midler og fremgangsmaate for deres fremstilling | |
US4317827A (en) | 4-[4(or 3)-Acylaminophenyl]pyridines and their use as cardiotonics | |
US4225601A (en) | 3-Hydroxy or hydroxymethyl-5-(4-pyridinyl)2(1H)-pyridinones, useful as cardiotonic agents and their preparation | |
US4304775A (en) | 3-Hydrazino-6-(pyridinyl) pyridazines and cardiotonic use thereof | |
US4376775A (en) | N-[4-(4-Pyridinyl)phenyl]ureas and their cardiotonic use | |
US4463008A (en) | 2-Alkoxy-5-(pyridinyl)pyridines and cardiotonic use thereof | |
US4363911A (en) | 1,2-Dihydro-6-[2-(dimethylamino)ethenyl]-2-oxo-5-(pyridinyl) nicotinonitriles | |
US4362735A (en) | 3-[(3-Oxo-1-butenyl)amino]-5-(pyridinyl)-2(1H)-pyridinones and their cardiotonic use | |
US4377585A (en) | Use of 4-[4(or 3)-aminophenyl]pyridines as cardiotonic agents | |
US4305943A (en) | 4-Amino-6-(pyridinyl)-3(2H)-pyridazinones and their use as cardiotonics | |
US4473571A (en) | 8-Substituted-2-(4-pyridinyl)-9H-purin-6-amines and their cardiotonic use | |
EP0074229A1 (fr) | Triazoles, agents anti sécrétions gastriques | |
US4361569A (en) | 3-(Hydroxy or hydroxymethyl)-6-methyl-5-(4-pyridinyl)-2(1H)-pyridinone and cardiotonic use thereof | |
US4354026A (en) | 3-Chloro-6-(pyridinyl)-pyridazines | |
US4503228A (en) | 2-(Pyridinyl)-4,5,6-pyrimidinetriamines | |
US4366319A (en) | Process for preparing 5-(pyridinyl)benzoxazol-2(3H)-ones | |
US4335131A (en) | Amrinone-N-glucuronide, salts and cardiotonic use thereof | |
US4310531A (en) | 5-(Pyridinyl)-benzoxazol-2(3H)-ones and their use as cardiotonics |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
NAL | Patent in force |
Ref document number: 8101205-6 Format of ref document f/p: F |
|
NUG | Patent has lapsed |
Ref document number: 8101205-6 Format of ref document f/p: F |