IL62161A - Iminium salts,their preparation,pharmaceutical compositions containing them and their use as intermediates for preparing 5-cyano-(or-carbamyl)-(3,4'-bipyridin)-6(1h)-one - Google Patents

Iminium salts,their preparation,pharmaceutical compositions containing them and their use as intermediates for preparing 5-cyano-(or-carbamyl)-(3,4'-bipyridin)-6(1h)-one

Info

Publication number: IL62161A
Authority: IL; Israel
Prior art keywords: bipyridin; carbamyl; intermediates; cyano; preparing
Prior art date: 1980-02-26

Application number

IL62161A

Other languages

English (en)

Other versions

IL62161A0 (en

Original Assignee

Sterling Drug Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1980-02-26

Filing date

1981-02-18

Publication date

1984-06-29

1981-02-18 Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc

1981-03-31 Publication of IL62161A0 publication Critical patent/IL62161A0/xx

1984-06-29 Publication of IL62161A publication Critical patent/IL62161A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/53—Nitrogen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pyridine Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

IL62161A 1980-02-26 1981-02-18 Iminium salts,their preparation,pharmaceutical compositions containing them and their use as intermediates for preparing 5-cyano-(or-carbamyl)-(3,4'-bipyridin)-6(1h)-one IL62161A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/124,808 US4264609A (en)	1980-02-26	1980-02-26	N-[3-Dimethylamino-2-(4-pyridinyl)-2-propenylidene]-N-methylmethaniminium chloride hydrochloride, its use in preparing 5-(cyano or carbamyl)-[3,4'-bipyridin]-6(1H)-one and its use as a cardiotonic

Publications (2)

Publication Number	Publication Date
IL62161A0 IL62161A0 (en)	1981-03-31
IL62161A true IL62161A (en)	1984-06-29

Family

ID=22416880

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL62161A IL62161A (en)	1980-02-26	1981-02-18	Iminium salts,their preparation,pharmaceutical compositions containing them and their use as intermediates for preparing 5-cyano-(or-carbamyl)-(3,4'-bipyridin)-6(1h)-one

Country Status (28)

Country	Link
US (1)	US4264609A (xx)
JP (1)	JPS56128758A (xx)
KR (2)	KR840002067B1 (xx)
AR (1)	AR230630A1 (xx)
AT (2)	AT380237B (xx)
AU (1)	AU541644B2 (xx)
BE (1)	BE887663A (xx)
CA (1)	CA1128523A (xx)
CH (1)	CH647509A5 (xx)
DE (1)	DE3107306A1 (xx)
DK (1)	DK171253B1 (xx)
ES (1)	ES499776A1 (xx)
FI (1)	FI76787C (xx)
FR (1)	FR2476646A1 (xx)
GB (1)	GB2070600B (xx)
HK (1)	HK71789A (xx)
IE (1)	IE51696B1 (xx)
IL (1)	IL62161A (xx)
IT (1)	IT1210992B (xx)
LU (1)	LU83169A1 (xx)
MX (1)	MX6908E (xx)
NL (1)	NL192109C (xx)
NO (1)	NO156689C (xx)
NZ (1)	NZ196282A (xx)
PH (2)	PH19904A (xx)
PT (1)	PT72573B (xx)
SE (2)	SE437514B (xx)
ZA (1)	ZA811124B (xx)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE77817T1 (de)	1985-04-30	1992-07-15	Dresden Arzneimittel	3-cyan-pyridine, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4072746A (en) *	1975-10-14	1978-02-07	Sterling Drug Inc.	3-Amino-5-(pyridinyl)-2(1H)-pyridinones
US4004012A (en) *	1975-10-14	1977-01-18	Sterling Drug Inc.	3-Cyano-5-(pyridinyl)-2(1H)-pyridinones

1980
- 1980-02-26 US US06/124,808 patent/US4264609A/en not_active Expired - Lifetime
1981
- 1981-02-17 NZ NZ196282A patent/NZ196282A/xx unknown
- 1981-02-18 IL IL62161A patent/IL62161A/xx not_active IP Right Cessation
- 1981-02-20 GB GB8105369A patent/GB2070600B/en not_active Expired
- 1981-02-20 ZA ZA00811124A patent/ZA811124B/xx unknown
- 1981-02-20 AU AU67487/81A patent/AU541644B2/en not_active Expired
- 1981-02-24 CH CH1222/81A patent/CH647509A5/fr not_active IP Right Cessation
- 1981-02-24 SE SE8101205A patent/SE437514B/sv not_active IP Right Cessation
- 1981-02-24 FR FR8103609A patent/FR2476646A1/fr active Granted
- 1981-02-24 IT IT8119952A patent/IT1210992B/it active
- 1981-02-24 PH PH25258A patent/PH19904A/en unknown
- 1981-02-25 AT AT0088581A patent/AT380237B/de not_active IP Right Cessation
- 1981-02-25 PT PT72573A patent/PT72573B/pt unknown
- 1981-02-25 BE BE1/10150A patent/BE887663A/fr not_active IP Right Cessation
- 1981-02-25 KR KR1019810000616A patent/KR840002067B1/ko active
- 1981-02-25 NO NO810639A patent/NO156689C/no unknown
- 1981-02-25 CA CA371,690A patent/CA1128523A/en not_active Expired
- 1981-02-25 IE IE397/81A patent/IE51696B1/en not_active IP Right Cessation
- 1981-02-25 ES ES499776A patent/ES499776A1/es not_active Expired
- 1981-02-25 FI FI810582A patent/FI76787C/fi not_active IP Right Cessation
- 1981-02-25 DK DK083981A patent/DK171253B1/da not_active IP Right Cessation
- 1981-02-25 NL NL8100922A patent/NL192109C/nl not_active IP Right Cessation
- 1981-02-25 MX MX819321U patent/MX6908E/es unknown
- 1981-02-26 LU LU83169A patent/LU83169A1/fr unknown
- 1981-02-26 DE DE19813107306 patent/DE3107306A1/de active Granted
- 1981-02-26 JP JP2759981A patent/JPS56128758A/ja active Granted
- 1981-02-26 AR AR284447A patent/AR230630A1/es active
1982
- 1982-03-01 PH PH26927A patent/PH17145A/en unknown
1983
- 1983-08-26 AT AT0305683A patent/AT380236B/de not_active IP Right Cessation
1984
- 1984-05-21 SE SE8402727A patent/SE452764B/sv not_active IP Right Cessation
- 1984-08-22 KR KR1019840005058A patent/KR840002066B1/ko not_active IP Right Cessation
1989
- 1989-09-07 HK HK717/89A patent/HK71789A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO810639L (no)	1981-08-27
ATA88581A (de)	1985-09-15
SE8402727L (sv)	1984-05-21
FI76787C (fi)	1988-12-12
MX6908E (es)	1986-11-07
IT1210992B (it)	1989-09-29
IT8119952A0 (it)	1981-02-24
AT380236B (de)	1986-04-25
CA1128523A (en)	1982-07-27
FI76787B (fi)	1988-08-31
PT72573B (en)	1982-02-12
DK83981A (da)	1981-08-27
SE8101205L (sv)	1981-08-27
PT72573A (pt)	1981-03-01
NL8100922A (nl)	1981-09-16
CH647509A5 (fr)	1985-01-31
FI810582L (fi)	1981-08-27
DK171253B1 (da)	1996-08-12
NL192109B (nl)	1996-10-01
US4264609A (en)	1981-04-28
FR2476646B1 (xx)	1984-08-17
SE452764B (sv)	1987-12-14
DE3107306A1 (de)	1981-12-17
FR2476646A1 (fr)	1981-08-28
IL62161A0 (en)	1981-03-31
PH17145A (en)	1984-06-04
IE810397L (en)	1981-08-26
JPH0141626B2 (xx)	1989-09-06
DE3107306C2 (xx)	1990-11-29
IE51696B1 (en)	1987-02-18
ZA811124B (en)	1982-03-31
NL192109C (nl)	1997-02-04
AU541644B2 (en)	1985-01-17
NO156689C (no)	1987-11-04
SE8402727D0 (sv)	1984-05-21
HK71789A (en)	1989-09-14
LU83169A1 (fr)	1981-09-11
JPS56128758A (en)	1981-10-08
AR230630A1 (es)	1984-05-31
NZ196282A (en)	1983-12-16
ATA305683A (de)	1985-09-15
PH19904A (en)	1986-08-13
GB2070600A (en)	1981-09-09
AU6748781A (en)	1981-09-03
GB2070600B (en)	1984-07-11
BE887663A (fr)	1981-08-25
NO156689B (no)	1987-07-27
AT380237B (de)	1986-04-25
KR840002066B1 (ko)	1984-11-09
KR830005143A (ko)	1983-08-03
SE437514B (sv)	1985-03-04
ES499776A1 (es)	1984-06-16
KR840002067B1 (ko)	1984-11-09

Similar Documents

Publication	Publication Date	Title
IL64665A (en)	1985-03-31	4-amino-6,7-dimethoxy-2-piperazino-quinazoline derivatives,their preparation and pharmaceutical compositions containing them
IL60086A (en)	1984-03-30	Pyrimidine compounds,their preparation and pharmaceutical compositions containing them
DE3163938D1 (en)	1984-07-12	Heterocyclic compounds, their preparation and pharmaceutical compositions containing them
IL62246A0 (en)	1981-05-20	2(1h)-pyridinone derivatives,their preparation and pharmaceutical compositions containing them
IL74244A0 (en)	1985-05-31	Quinoline and naphthyridine derivatives,their preparation and pharmaceutical compositions containing them
DE3068706D1 (en)	1984-08-30	Novel benzodiazepine compounds, their preparation, intermediates employed in their preparation, and pharmaceutical compositions containing them
IL75733A0 (en)	1985-11-29	1,6-naphthyridin-2(1h)-ones,their preparation and pharmaceutical compositions containing them
IL60472A (en)	1983-09-30	Substituted heterocyclic phenoxyamines,their preparation and pharmaceutical compositions containing them
DE3160987D1 (en)	1983-11-03	Benzodiazepine derivatives, intermediates and processes for preparing them, their use and pharmaceutical compositions containing them
IL68710A (en)	1986-09-30	2-(1h)-pyridinone derivatives,their preparation and pharmaceutical compositions containing them
DE3173643D1 (en)	1986-03-13	Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and intermediates for their preparation
IL71648A (en)	1987-11-30	5-acyl-2-(1h)-pyridinones,their preparation and pharmaceutical compositions containing them
DE3160986D1 (en)	1983-11-03	Benzodiazepine derivatives, intermediates and processes for preparing them, their use and pharmaceutical compositions containing them
EP0043054A3 (en)	1982-03-17	Pyrimidine derivatives, their preparation and use, medicaments containing them and intermediates for their preparation
JPS57123164A (en)	1982-07-31	Hydroxyphenyltetrahydropyridine novel derivatives and their salts, manufacture and intermediates, use as drug and composition containing same
IL62970A (en)	1985-01-31	Substituted phenoxy-aminopropanol derivatives and intermediates therefor,their preparation and pharmaceutical compositions containing them
IL62161A (en)	1984-06-29	Iminium salts,their preparation,pharmaceutical compositions containing them and their use as intermediates for preparing 5-cyano-(or-carbamyl)-(3,4'-bipyridin)-6(1h)-one
SG62087G (en)	1987-10-23	Heterocyclic compounds, their preparation and pharmaceutical compositions containing them
IL72555A (en)	1988-02-29	5-substituted-1,6-naphthyridin-2(1h)-one derivatives,their preparation,pharmaceutical compositions containing them and intermediates therefor
DE3171021D1 (en)	1985-07-25	Pyrrolo-(3,4-d)-benzapines, process and intermediates for their preparation and pharmaceutical compositions containing them
IL64328A0 (en)	1982-02-28	Naphthyridine derivatives,their preparation and pharmaceutical compositions containing them
ZA829444B (en)	1983-04-27	Heterocyclic compounds, their preparation and pharmaceutical compositions containing them
IL62159A0 (en)	1981-03-31	Preparation of 5-cyano-(3,4'-bipyridin)-6(1h)-one
ZA853268B (en)	1985-12-24	New quinoline derivatives,their preparation and therapeutic compositions containing the same
IL64672A0 (en)	1982-03-31	Substituted tetrahydro-1,2,4-oxadiazin-5-one derivatives,their preparation and pharmaceutical compositions containing them

Legal Events

Date	Code	Title
1997-07-13	HC	Change of name of proprietor(s)
1997-07-13	HP	Change in proprietorship
1999-07-14	KB	Patent renewed
2000-06-01	HC	Change of name of proprietor(s)
2001-07-24	EXP	Patent expired