RS60828B1 - Cd40l-specifične konstrukcije izvedene iz tn3 i metode za njihovu primenu - Google Patents
Cd40l-specifične konstrukcije izvedene iz tn3 i metode za njihovu primenuInfo
- Publication number
- RS60828B1 RS60828B1 RS20201146A RSP20201146A RS60828B1 RS 60828 B1 RS60828 B1 RS 60828B1 RS 20201146 A RS20201146 A RS 20201146A RS P20201146 A RSP20201146 A RS P20201146A RS 60828 B1 RS60828 B1 RS 60828B1
- Authority
- RS
- Serbia
- Prior art keywords
- cd40l
- methods
- specific
- derived scaffolds
- scaffolds
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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- A—HUMAN NECESSITIES
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2318/00—Antibody mimetics or scaffolds
- C07K2318/20—Antigen-binding scaffold molecules wherein the scaffold is not an immunoglobulin variable region or antibody mimetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161546028P | 2011-10-11 | 2011-10-11 | |
EP12840074.4A EP2771022B1 (en) | 2011-10-11 | 2012-10-10 | Cd40l-specific tn3-derived scaffolds and methods of use thereof |
PCT/US2012/059477 WO2013055745A2 (en) | 2011-10-11 | 2012-10-10 | Cd40l-specific tn3-derived scaffolds and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
RS60828B1 true RS60828B1 (sr) | 2020-10-30 |
Family
ID=48082729
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RS20201146A RS60828B1 (sr) | 2011-10-11 | 2012-10-10 | Cd40l-specifične konstrukcije izvedene iz tn3 i metode za njihovu primenu |
Country Status (22)
Country | Link |
---|---|
US (4) | US10000553B2 (sr) |
EP (2) | EP2771022B1 (sr) |
JP (4) | JP6140712B2 (sr) |
KR (3) | KR102132997B1 (sr) |
CN (3) | CN116063509A (sr) |
AU (1) | AU2012323316B2 (sr) |
BR (1) | BR112014008804A2 (sr) |
CA (1) | CA2851667A1 (sr) |
CY (1) | CY1123690T1 (sr) |
DK (1) | DK2771022T3 (sr) |
ES (1) | ES2819075T3 (sr) |
HK (1) | HK1201463A1 (sr) |
HR (1) | HRP20201513T1 (sr) |
HU (1) | HUE051439T2 (sr) |
LT (1) | LT2771022T (sr) |
MX (2) | MX367013B (sr) |
PT (1) | PT2771022T (sr) |
RS (1) | RS60828B1 (sr) |
RU (2) | RU2019133467A (sr) |
SG (2) | SG11201400567QA (sr) |
SI (1) | SI2771022T1 (sr) |
WO (1) | WO2013055745A2 (sr) |
Families Citing this family (15)
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DK3097926T3 (da) * | 2007-11-01 | 2019-12-16 | Univ Arkansas | Sammensætninger og fremgangsmåder til forstærkning af immunreaktioner på Eimeria |
RU2019133467A (ru) * | 2011-10-11 | 2020-07-06 | МЕДИММЬЮН, ЭлЭлСи | Cd40l-специфичные каркасные структуры, происходящие из tn3, и способы их применения |
MA41044A (fr) | 2014-10-08 | 2017-08-15 | Novartis Ag | Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer |
AU2015345202B2 (en) | 2014-11-10 | 2021-05-13 | Medimmune Limited | Binding molecules specific for CD73 and uses thereof |
CN107428817B (zh) | 2015-03-12 | 2022-07-12 | 免疫医疗有限责任公司 | 纯化白蛋白融合蛋白的方法 |
KR101810778B1 (ko) * | 2015-06-23 | 2017-12-20 | 서울대학교산학협력단 | Cd154 결합 폴리펩타이드 및 그 용도 |
ES2944982T3 (es) | 2015-08-05 | 2023-06-27 | Janssen Biotech Inc | Anticuerpos anti-CD154 y métodos para utilizarlos |
BR112019014147A2 (pt) * | 2017-01-09 | 2020-02-11 | Biomunex Pharmaceuticals | Ligante polipeptídico para a preparação de anticorpos multiespecíficos |
WO2019108541A1 (en) * | 2017-11-28 | 2019-06-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Recombinant rsv g proteins and their use |
US20210317220A1 (en) * | 2018-09-24 | 2021-10-14 | Janssen Biotech, Inc. | Method of providing safe administration of an anti-cd154 antibody |
AU2019346457A1 (en) * | 2018-09-26 | 2021-05-20 | Viela Bio, Inc. | CD40l antagonist and uses thereof |
WO2020086885A2 (en) * | 2018-10-24 | 2020-04-30 | Brandeis University | Multivalent glycopeptides that tightly bind to carbohydrate-binding monoclonal antibody family pgt128 |
CN113227135A (zh) | 2018-12-28 | 2021-08-06 | 斯帕克斯治疗公司 | 用于治疗癌症和其他疾病的对紧密连接蛋白18.2具有特异性的结合分子、其组合物和方法 |
CN111440253B (zh) * | 2019-01-17 | 2021-08-27 | 中国科学院上海药物研究所 | 立方形环糊精骨架-rgd组合物及其制备方法 |
AU2022276507A1 (en) * | 2021-05-21 | 2023-12-07 | Viela Bio, Inc. | Cd40l antagonist and uses thereof in the treatment of lupus nephritis |
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