PT1152750E - Composições de n-benzoil estaurosporina espontaneamente dispersíveis - Google Patents

Composições de n-benzoil estaurosporina espontaneamente dispersíveis Download PDF

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Publication number
PT1152750E
PT1152750E PT00909165T PT00909165T PT1152750E PT 1152750 E PT1152750 E PT 1152750E PT 00909165 T PT00909165 T PT 00909165T PT 00909165 T PT00909165 T PT 00909165T PT 1152750 E PT1152750 E PT 1152750E
Authority
PT
Portugal
Prior art keywords
spontaneously dispersible
benzoyl staurosporine
compositions
staurosporine compositions
benzoyl
Prior art date
Application number
PT00909165T
Other languages
English (en)
Inventor
Barbara Haeberlin
Graham Paul Matthews
Original Assignee
Novartis Ag
Novartis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10847896&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1152750(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag, Novartis Pharma Gmbh filed Critical Novartis Ag
Publication of PT1152750E publication Critical patent/PT1152750E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
PT00909165T 1999-02-16 2000-02-14 Composições de n-benzoil estaurosporina espontaneamente dispersíveis PT1152750E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9903547.9A GB9903547D0 (en) 1999-02-16 1999-02-16 Organic compounds

Publications (1)

Publication Number Publication Date
PT1152750E true PT1152750E (pt) 2009-08-07

Family

ID=10847896

Family Applications (1)

Application Number Title Priority Date Filing Date
PT00909165T PT1152750E (pt) 1999-02-16 2000-02-14 Composições de n-benzoil estaurosporina espontaneamente dispersíveis

Country Status (34)

Country Link
US (3) US20020061873A1 (pt)
EP (1) EP1152750B1 (pt)
JP (2) JP5057610B2 (pt)
KR (2) KR20080064914A (pt)
CN (1) CN100367930C (pt)
AR (2) AR022589A1 (pt)
AT (1) ATE430554T1 (pt)
AU (1) AU765776B2 (pt)
BR (1) BRPI0008228B8 (pt)
CA (1) CA2362277C (pt)
CL (1) CL2009001682A1 (pt)
CZ (1) CZ303979B6 (pt)
DE (1) DE60042151D1 (pt)
DK (1) DK1152750T3 (pt)
EC (1) ECSP083351A (pt)
ES (1) ES2326783T3 (pt)
GB (1) GB9903547D0 (pt)
HK (1) HK1045807B (pt)
HU (1) HUP0105364A3 (pt)
ID (1) ID30504A (pt)
IL (3) IL144512A0 (pt)
MY (1) MY128362A (pt)
NO (1) NO331232B1 (pt)
NZ (1) NZ513529A (pt)
PE (1) PE20001499A1 (pt)
PL (1) PL198330B1 (pt)
PT (1) PT1152750E (pt)
RU (1) RU2266121C2 (pt)
SI (1) SI1152750T1 (pt)
SK (1) SK286967B6 (pt)
TR (1) TR200102385T2 (pt)
TW (1) TWI240636B (pt)
WO (1) WO2000048571A1 (pt)
ZA (1) ZA200106677B (pt)

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US6200968B1 (en) * 1998-08-06 2001-03-13 Cephalon, Inc. Particle-forming compositions containing fused pyrrolocarbazoles
US7795246B2 (en) 1998-08-06 2010-09-14 Cephalon, Inc. Particle-forming compositions containing fused pyrrolocarbazoles
EP1372611B1 (en) * 2001-03-26 2006-05-17 Novartis AG Pharmaceutical composition comprising a poorly water-soluble staurosporine, a surfactant and a water-soluble polymer
KR20080091866A (ko) 2001-05-16 2008-10-14 노파르티스 아게 Ν-｛5-[4-(4-메틸-피페라지노-메틸)-벤조일아미도]-2-메틸페닐｝-4-(3-피리딜)-2-피리미딘-아민 및 화학치료제를 포함하는 배합물
ATE335490T1 (de) 2001-10-30 2006-09-15 Novartis Pharma Gmbh Staurosporin-derivate als hemmer der flt3- rezeptor-tyrosinkinase-wirkung
GB0206215D0 (en) 2002-03-15 2002-05-01 Novartis Ag Organic compounds
CA2492989C (en) * 2002-07-23 2012-11-20 Novartis Ag Ophthalmic ointment composition comprising a drug, an ointment base and a solubilizing/dispersing agent
US7842791B2 (en) 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
TWI324604B (en) * 2003-06-18 2010-05-11 Novartis Ag New use of staurosporine derivatives
GB0512324D0 (en) 2005-06-16 2005-07-27 Novartis Ag Organic compounds
GB0419159D0 (en) * 2004-08-27 2004-09-29 Novartis Ag Organic compounds
GT200500310A (es) 2004-11-19 2006-06-19 Compuestos organicos
WO2008021347A2 (en) * 2006-08-16 2008-02-21 Novartis Ag Method for making solid dispersions of highly crystalline therapeutic compounds
FR2918566B1 (fr) 2007-07-11 2009-10-09 Pierre Fabre Medicament Sa Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine.
WO2009067221A2 (en) * 2007-11-20 2009-05-28 Cephalon, Inc. Microemulsion containing indolocarbazole compound and dosage forms containing the same
EP2229936B1 (en) * 2009-03-09 2015-05-06 PharmaSol GmbH Nanonized testosterone formulations for improved bioavailability
WO2011000811A2 (en) * 2009-06-30 2011-01-06 Novartis Ag Organic compounds
CN102781425B (zh) * 2009-12-22 2014-08-13 利奥制药有限公司 含有维生素d类似物以及溶剂和表面活性剂混合物的皮肤用组合物
JO3337B1 (ar) 2010-12-13 2019-03-13 Debiopharm Sa تركيبات صيدلية تشمل أليسبوريفير
US9387446B2 (en) 2011-09-22 2016-07-12 Ariel-University Research And Development Company Ltd. Emulsions and methods of making emulsions
KR20190032265A (ko) * 2015-12-09 2019-03-27 포스파제닉스 리미티드 약제학적 제형
CN108601732A (zh) 2015-12-09 2018-09-28 磷肌酸有限公司 药物制剂
WO2018112512A1 (en) 2016-12-21 2018-06-28 Phosphagenics Limited Process
WO2021097256A1 (en) 2019-11-14 2021-05-20 Cohbar, Inc. Cxcr4 antagonist peptides

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US4963367A (en) 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
US4735939A (en) 1987-02-27 1988-04-05 The Dow Chemical Company Insecticidal activity of staurosporine
US5093330A (en) * 1987-06-15 1992-03-03 Ciba-Geigy Corporation Staurosporine derivatives substituted at methylamino nitrogen
DE3824034C1 (pt) * 1988-07-15 1989-09-14 Gustav 7290 Freudenstadt De Memminger
GB2222770B (en) * 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
AU668509B2 (en) 1991-04-19 1996-05-09 Affinity Biotech, Inc. Convertible microemulsion formulations
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GB9325395D0 (en) * 1993-12-11 1994-02-16 Ciba Geigy Ag Compositions
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JPH10501527A (ja) * 1994-06-01 1998-02-10 チバ−ガイギー アクチェンゲゼルシャフト 多重薬剤耐性細胞を抗腫瘍剤に対して感受性にするためのインドロカルバゾール誘導体
GB2308545B (en) 1994-10-26 1999-06-02 Novartis Ag Pharmaceutical microemulsion preconcentrates
IL115742A (en) 1994-10-26 2000-06-01 Novartis Ag Pharmaceutical compositions comprising a difficultly soluble active agent a hydrophilic phase a lipophilic phase and a surfactant
EP0711557A1 (de) * 1994-11-09 1996-05-15 Ciba-Geigy Ag Pharmazeutische Formulierungsgrundlage
EP0733372A3 (de) * 1995-03-21 1998-05-20 Ciba-Geigy Ag Pharmazeutische Formulierungsgrundlage für Nanosuspensionen
AU4491697A (en) 1996-09-27 1998-04-17 Trega Biosciences, Inc. Compositions of therapeutic agents suitable for oral administration
DE19641672A1 (de) 1996-10-10 1998-04-16 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen auf der Basis von ethylenoxidfreien und propylenoxidfreien Emulgatoren zur Herstellung von Mikroemulsionsgelen
US5827522A (en) 1996-10-30 1998-10-27 Troy Corporation Microemulsion and method
NZ314060A (en) 1997-01-13 1997-08-22 Bernard Charles Sherman Pharmaceutical microemulsion preconcentrate comprising cyclosporin dissolved in a solvent system comprising hydrophobic solvent(s) and surfactant(s)
TR199901686T2 (xx) * 1997-01-30 1999-09-21 Norvartis Ag Esasen ya�s�z farmakolojik kompozisyonlar� i�eren sert jelatin kaps�ller.
RU2203648C2 (ru) 1997-07-29 2003-05-10 Фармация Энд Апджон Компани Самоэмульгирующаяся композиция для липофильных соединений
CZ297206B6 (cs) 1997-07-29 2006-10-11 Pharmacia & Upjohn Company Farmaceutická kompozice a samoemulgující formulace pro lipofilní slouceniny
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US6979456B1 (en) * 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
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US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions

Also Published As

Publication number Publication date
PL198330B1 (pl) 2008-06-30
CN1339963A (zh) 2002-03-13
US20080070897A1 (en) 2008-03-20
KR100880859B1 (ko) 2009-01-30
JP5057610B2 (ja) 2012-10-24
CA2362277C (en) 2010-03-30
BRPI0008228B1 (pt) 2016-08-23
TR200102385T2 (tr) 2002-09-23
ECSP083351A (es) 2008-08-29
AR022589A1 (es) 2002-09-04
NZ513529A (en) 2003-10-31
SK286967B6 (sk) 2009-08-06
TWI240636B (en) 2005-10-01
KR20080064914A (ko) 2008-07-09
IL144512A (en) 2011-03-31
US8722664B2 (en) 2014-05-13
US20140056974A1 (en) 2014-02-27
NO20013964L (no) 2001-10-15
HK1045807B (zh) 2008-12-05
PL350556A1 (en) 2002-12-16
SI1152750T1 (sl) 2009-10-31
MY128362A (en) 2007-01-31
US8575147B2 (en) 2013-11-05
NO20013964D0 (no) 2001-08-15
GB9903547D0 (en) 1999-04-07
CN100367930C (zh) 2008-02-13
ATE430554T1 (de) 2009-05-15
CL2009001682A1 (es) 2010-07-23
NO331232B1 (no) 2011-11-07
US20020061873A1 (en) 2002-05-23
PE20001499A1 (es) 2001-01-12
ID30504A (id) 2001-12-13
AR082579A2 (es) 2012-12-19
KR20010093281A (ko) 2001-10-27
CZ303979B6 (cs) 2013-07-31
WO2000048571A1 (en) 2000-08-24
BRPI0008228B8 (pt) 2021-05-25
ZA200106677B (en) 2003-01-14
AU3154200A (en) 2000-09-04
JP2002537242A (ja) 2002-11-05
SK11722001A3 (sk) 2001-12-03
CA2362277A1 (en) 2000-08-24
ES2326783T3 (es) 2009-10-20
EP1152750B1 (en) 2009-05-06
AU765776B2 (en) 2003-10-02
IL192666A0 (en) 2009-02-11
HUP0105364A2 (hu) 2002-05-29
DE60042151D1 (de) 2009-06-18
DK1152750T3 (da) 2009-08-24
BR0008228A (pt) 2001-10-30
IL144512A0 (en) 2002-05-23
EP1152750A1 (en) 2001-11-14
CZ20012931A3 (cs) 2001-11-14
HUP0105364A3 (en) 2003-02-28
HK1045807A1 (en) 2002-12-13
RU2266121C2 (ru) 2005-12-20
JP2012111763A (ja) 2012-06-14

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