PL1885399T3 - Humanizowane przeciwciała anty-CD40 i sposoby ich stosowania - Google Patents
Humanizowane przeciwciała anty-CD40 i sposoby ich stosowaniaInfo
- Publication number
- PL1885399T3 PL1885399T3 PL06771453T PL06771453T PL1885399T3 PL 1885399 T3 PL1885399 T3 PL 1885399T3 PL 06771453 T PL06771453 T PL 06771453T PL 06771453 T PL06771453 T PL 06771453T PL 1885399 T3 PL1885399 T3 PL 1885399T3
- Authority
- PL
- Poland
- Prior art keywords
- antibodies
- methods
- humanized anti
- antigen
- expression
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68485305P | 2005-05-26 | 2005-05-26 | |
PCT/US2006/020688 WO2006128103A2 (en) | 2005-05-26 | 2006-05-26 | Humanized anti-cd40 antibodies and their methods of use |
EP06771453A EP1885399B1 (en) | 2005-05-26 | 2006-05-26 | Humanized anti-cd40 antibodies and their methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
PL1885399T3 true PL1885399T3 (pl) | 2011-04-29 |
Family
ID=37452957
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL06771453T PL1885399T3 (pl) | 2005-05-26 | 2006-05-26 | Humanizowane przeciwciała anty-CD40 i sposoby ich stosowania |
Country Status (19)
Country | Link |
---|---|
US (4) | US8303955B2 (pl) |
EP (1) | EP1885399B1 (pl) |
JP (1) | JP5027804B2 (pl) |
KR (1) | KR100991010B1 (pl) |
CN (1) | CN101237882B (pl) |
AT (1) | ATE485057T1 (pl) |
AU (1) | AU2006249305B2 (pl) |
BR (1) | BRPI0610470A2 (pl) |
CA (1) | CA2609269C (pl) |
CR (1) | CR9562A (pl) |
DE (1) | DE602006017690D1 (pl) |
EC (1) | ECSP078026A (pl) |
ES (1) | ES2354865T3 (pl) |
IL (1) | IL187594A0 (pl) |
MA (1) | MA29595B1 (pl) |
NO (1) | NO341793B1 (pl) |
PL (1) | PL1885399T3 (pl) |
RU (1) | RU2407544C2 (pl) |
WO (1) | WO2006128103A2 (pl) |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
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US6946129B1 (en) | 1999-06-08 | 2005-09-20 | Seattle Genetics, Inc. | Recombinant anti-CD40 antibody and uses thereof |
US8303955B2 (en) * | 2005-05-26 | 2012-11-06 | Seattle Genetics, Inc. | Humanized anti-CD40 antibodies and their methods of use |
AU2006329944A1 (en) * | 2005-12-09 | 2007-07-05 | Seattle Genetics, Inc. | Methods of using CD40 binding agents |
WO2008091954A2 (en) * | 2007-01-23 | 2008-07-31 | Xencor, Inc. | Optimized cd40 antibodies and methods of using the same |
JP5730576B2 (ja) | 2007-11-07 | 2015-06-10 | ジェネンテック, インコーポレイテッド | 抗cd40抗体による治療に対するb細胞リンパ腫の応答性を評価するための方法及び組成物 |
AU2010222929B2 (en) | 2008-07-16 | 2013-07-25 | Baylor Research Institute | Antigen presenting cell targeted anti-viral vaccines |
FR2942799B1 (fr) * | 2009-03-06 | 2011-02-25 | Lfb Biotechnologies | Anticorps monoclonal anti-rhesus d |
DK2406289T3 (en) | 2009-03-10 | 2017-05-01 | Baylor Res Inst | ANTIGEN PRESENTING CELL TARGETED ANTIVIRUS VACCINES |
US9562104B2 (en) | 2009-03-10 | 2017-02-07 | Baylor Research Institute | Anti-CD40 antibodies |
CA2758523C (en) | 2009-04-18 | 2019-03-12 | Genentech, Inc. | Methods for assessing responsiveness of b-cell lymphoma to treatment with anti-cd40 antibodies |
US20130052194A1 (en) * | 2009-12-16 | 2013-02-28 | The Trustees Of The University Of Pennsylvania | Anti-prostate cancer antibodies and methods of detection and treatment of prostate cancer using the same |
HUE038788T2 (hu) | 2010-03-31 | 2018-11-28 | Boehringer Ingelheim Int | Anti-CD40 antitestek |
PT2683406T (pt) | 2011-03-11 | 2019-07-08 | Beth Israel Deaconess Medical Ct Inc | Anticorpos anti-cd40 e utilização dos mesmos |
TW201300418A (zh) | 2011-03-25 | 2013-01-01 | Baylor Res Inst | 用於抗c型肝炎病毒免疫之組合物及方法 |
EP3508500A1 (en) | 2011-04-29 | 2019-07-10 | Apexigen, Inc. | Anti-cd40 antibodies and methods of use |
GB201115280D0 (en) | 2011-09-05 | 2011-10-19 | Alligator Bioscience Ab | Antibodies, uses and methods |
RU2019133467A (ru) * | 2011-10-11 | 2020-07-06 | МЕДИММЬЮН, ЭлЭлСи | Cd40l-специфичные каркасные структуры, происходящие из tn3, и способы их применения |
AR090263A1 (es) | 2012-03-08 | 2014-10-29 | Hoffmann La Roche | Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma |
CN104918957B (zh) * | 2012-10-30 | 2018-11-16 | 埃派斯进有限公司 | 抗-cd40抗体及其使用方法 |
US9353150B2 (en) | 2012-12-04 | 2016-05-31 | Massachusetts Institute Of Technology | Substituted pyrazino[1′,2′:1 ,5]pyrrolo[2,3-b]-indole-1,4-diones for cancer treatment |
AR097584A1 (es) | 2013-09-12 | 2016-03-23 | Hoffmann La Roche | Terapia de combinación de anticuerpos contra el csf-1r humano y anticuerpos contra el pd-l1 humano |
AU2015204503B2 (en) | 2014-01-13 | 2020-07-09 | Baylor Research Institute | Novel vaccines against HPV and HPV-related diseases |
US10144782B2 (en) | 2014-04-30 | 2018-12-04 | Max-Delbrück-Centrum Für Molekulare Medizin In Der Helmholtz-Gemeinschaft | Humanized antibodies against CD269 (BCMA) |
MX2017001864A (es) | 2014-08-12 | 2017-08-02 | Alligator Bioscience Ab | Tratamientos conjuntos con anticuerpos anti cd40. |
SG11201702598XA (en) * | 2014-10-29 | 2017-05-30 | Seattle Genetics Inc | Dosage and administration of non-fucosylated anti-cd40 antibodies |
EA201791093A1 (ru) * | 2014-11-18 | 2018-04-30 | Янссен Фармацевтика Нв | Антитела к cd47, способы и применение |
BR112017020952A2 (pt) | 2015-04-13 | 2018-07-10 | Five Prime Therapeutics Inc | método de tratamento de câncer, composição e uso da composição |
WO2017040566A1 (en) * | 2015-09-01 | 2017-03-09 | Boehringer Ingelheim International Gmbh | Use of anti-cd40 antibodies for treatment of lupus nephritis |
CN116063481A (zh) | 2015-09-04 | 2023-05-05 | 普里玛托普医疗股份有限公司 | 人源化抗-cd40抗体及其用途 |
CN109069622A (zh) | 2015-09-30 | 2018-12-21 | 詹森生物科技公司 | 特异性结合人cd40的拮抗性抗体和使用方法 |
US20170101471A1 (en) * | 2015-10-08 | 2017-04-13 | The Board Of Trustees Of The Leland Stanford Junior University | Blockade of tim-1 for treating graft-versus-host disease |
BR112018008904A2 (pt) | 2015-11-03 | 2018-11-27 | Janssen Biotech Inc | anticorpos que se ligam especificamente a tim-3 e seus usos |
EA039944B1 (ru) * | 2016-01-27 | 2022-03-30 | Бёрингер Ингельхайм Интернациональ Гмбх | Применение антител к cd40 для лечения волчаночного нефрита |
US10918627B2 (en) | 2016-05-11 | 2021-02-16 | Massachusetts Institute Of Technology | Convergent and enantioselective total synthesis of Communesin analogs |
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EP3732198A1 (en) * | 2017-12-27 | 2020-11-04 | Bristol-Myers Squibb Company | Anti-cd40 antibodies and uses thereof |
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US11401339B2 (en) | 2018-08-23 | 2022-08-02 | Seagen Inc. | Anti-TIGIT antibodies |
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JP7221379B2 (ja) | 2018-10-01 | 2023-02-13 | エフ・ホフマン-ラ・ロシュ・アクチェンゲゼルシャフト | 抗fapクローン212を含む二重特異性抗原結合分子 |
WO2020070288A1 (en) | 2018-10-05 | 2020-04-09 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and systems for controlling the agonistic properties of antibody variable domains by light |
KR20210097750A (ko) | 2018-11-30 | 2021-08-09 | 지앙수 헨그루이 메디슨 컴퍼니 리미티드 | Cd40 항체 약학 조성물 및 이의 용도 |
TW202039558A (zh) | 2018-11-30 | 2020-11-01 | 大陸商江蘇恆瑞醫藥股份有限公司 | 抗cd40抗體、其抗原結合片段及其醫藥用途 |
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WO2020253722A1 (en) * | 2019-06-17 | 2020-12-24 | Eucure (Beijing) Biopharma Co., Ltd | Anti-cd40 antibodies and uses thereof |
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JP2023532339A (ja) | 2020-06-29 | 2023-07-27 | フラグシップ パイオニアリング イノベーションズ ブイ,インコーポレーテッド | サノトランスミッションを促進するためにエンジニアリングされたウイルス及び癌の処置におけるそれらの使用 |
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TW202233248A (zh) | 2020-11-08 | 2022-09-01 | 美商西健公司 | 組合療法 |
JP2024512669A (ja) | 2021-03-31 | 2024-03-19 | フラグシップ パイオニアリング イノベーションズ ブイ,インコーポレーテッド | タノトランスミッションポリペプチド及び癌の処置におけるそれらの使用 |
TW202314247A (zh) | 2021-05-25 | 2023-04-01 | 美商思進公司 | 量化抗cd40抗體之方法 |
CN115403670A (zh) | 2021-05-26 | 2022-11-29 | 安徽瀚海博兴生物技术有限公司 | 抗cd40抗体及其用途 |
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-
2006
- 2006-05-26 US US11/913,305 patent/US8303955B2/en active Active
- 2006-05-26 AT AT06771453T patent/ATE485057T1/de not_active IP Right Cessation
- 2006-05-26 CA CA2609269A patent/CA2609269C/en active Active
- 2006-05-26 EP EP06771453A patent/EP1885399B1/en active Active
- 2006-05-26 DE DE602006017690T patent/DE602006017690D1/de active Active
- 2006-05-26 JP JP2008513805A patent/JP5027804B2/ja active Active
- 2006-05-26 BR BRPI0610470-3A patent/BRPI0610470A2/pt not_active IP Right Cessation
- 2006-05-26 PL PL06771453T patent/PL1885399T3/pl unknown
- 2006-05-26 WO PCT/US2006/020688 patent/WO2006128103A2/en active Application Filing
- 2006-05-26 AU AU2006249305A patent/AU2006249305B2/en active Active
- 2006-05-26 RU RU2007148932/10A patent/RU2407544C2/ru active
- 2006-05-26 KR KR1020077030332A patent/KR100991010B1/ko active IP Right Grant
- 2006-05-26 ES ES06771453T patent/ES2354865T3/es active Active
- 2006-05-26 CN CN2006800271172A patent/CN101237882B/zh active Active
-
2007
- 2007-11-22 IL IL187594A patent/IL187594A0/en unknown
- 2007-12-06 CR CR9562A patent/CR9562A/es not_active Application Discontinuation
- 2007-12-11 MA MA30474A patent/MA29595B1/fr unknown
- 2007-12-12 NO NO20076404A patent/NO341793B1/no unknown
- 2007-12-17 EC EC2007008026A patent/ECSP078026A/es unknown
-
2012
- 2012-09-19 US US13/622,517 patent/US8492531B2/en active Active
-
2013
- 2013-06-25 US US13/926,817 patent/US20130315900A1/en not_active Abandoned
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2014
- 2014-03-10 US US14/202,923 patent/US20140193405A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE602006017690D1 (de) | 2010-12-02 |
AU2006249305B2 (en) | 2012-10-18 |
AU2006249305A1 (en) | 2006-11-30 |
IL187594A0 (en) | 2008-03-20 |
CR9562A (es) | 2008-03-06 |
US20090181015A1 (en) | 2009-07-16 |
WO2006128103A3 (en) | 2007-01-18 |
NO20076404L (no) | 2008-02-13 |
CN101237882A (zh) | 2008-08-06 |
RU2407544C2 (ru) | 2010-12-27 |
US8303955B2 (en) | 2012-11-06 |
EP1885399A4 (en) | 2009-04-22 |
US20130023047A1 (en) | 2013-01-24 |
WO2006128103A2 (en) | 2006-11-30 |
EP1885399A2 (en) | 2008-02-13 |
EP1885399B1 (en) | 2010-10-20 |
ATE485057T1 (de) | 2010-11-15 |
JP2008541733A (ja) | 2008-11-27 |
JP5027804B2 (ja) | 2012-09-19 |
MA29595B1 (fr) | 2008-07-01 |
BRPI0610470A2 (pt) | 2010-06-22 |
KR100991010B1 (ko) | 2010-10-29 |
NO341793B1 (no) | 2018-01-22 |
ECSP078026A (es) | 2008-03-26 |
US20130315900A1 (en) | 2013-11-28 |
CA2609269A1 (en) | 2006-11-30 |
ES2354865T3 (es) | 2011-03-18 |
CN101237882B (zh) | 2012-08-15 |
RU2007148932A (ru) | 2009-07-10 |
US20140193405A1 (en) | 2014-07-10 |
US8492531B2 (en) | 2013-07-23 |
KR20080030958A (ko) | 2008-04-07 |
CA2609269C (en) | 2014-08-05 |
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