JPS5144499B1
(es)
|
1970-08-29 |
1976-11-29 |
|
|
JPS5334319B2
(es)
|
1971-12-28 |
1978-09-20 |
|
|
JPS5616428B2
(es)
|
1973-04-13 |
1981-04-16 |
|
|
JPS6048972B2
(ja)
|
1975-08-08 |
1985-10-30 |
株式会社日立製作所 |
方向比較搬送保護継電装置
|
JPS5816170B2
(ja)
|
1977-03-16 |
1983-03-30 |
旭化成株式会社 |
乾式画像形成材料
|
US4208479A
(en)
|
1977-07-14 |
1980-06-17 |
Syva Company |
Label modified immunoassays
|
JPS5970B2
(ja)
|
1978-02-10 |
1984-01-05 |
エプソン株式会社 |
小型プリンタの紙送り機構
|
JPS55134615A
(en)
|
1979-04-05 |
1980-10-20 |
Ishigaki Kiko Kk |
Removing device for cake in filter press
|
JPS5912436B2
(ja)
|
1980-08-05 |
1984-03-23 |
ファナック株式会社 |
工業用ロボットの安全機構
|
JPS6022444B2
(ja)
|
1980-11-08 |
1985-06-01 |
日立化成工業株式会社 |
集成マイカ材料,集成マイカプリプレグ材料及び集成マイカ製品
|
US4474893A
(en)
|
1981-07-01 |
1984-10-02 |
The University of Texas System Cancer Center |
Recombinant monoclonal antibodies
|
US4444878A
(en)
|
1981-12-21 |
1984-04-24 |
Boston Biomedical Research Institute, Inc. |
Bispecific antibody determinants
|
JPS58201994A
(ja)
|
1982-05-21 |
1983-11-25 |
Hideaki Hagiwara |
抗原特異的ヒト免疫グロブリンの生産方法
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
GB8607679D0
(en)
|
1986-03-27 |
1986-04-30 |
Winter G P |
Recombinant dna product
|
WO1988007089A1
(en)
|
1987-03-18 |
1988-09-22 |
Medical Research Council |
Altered antibodies
|
US5004697A
(en)
|
1987-08-17 |
1991-04-02 |
Univ. Of Ca |
Cationized antibodies for delivery through the blood-brain barrier
|
US5322678A
(en)
|
1988-02-17 |
1994-06-21 |
Neorx Corporation |
Alteration of pharmacokinetics of proteins by charge modification
|
US6010902A
(en)
|
1988-04-04 |
2000-01-04 |
Bristol-Meyers Squibb Company |
Antibody heteroconjugates and bispecific antibodies for use in regulation of lymphocyte activity
|
IL89491A0
(en)
|
1988-11-17 |
1989-09-10 |
Hybritech Inc |
Bifunctional chimeric antibodies
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
DE3920358A1
(de)
|
1989-06-22 |
1991-01-17 |
Behringwerke Ag |
Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung
|
EP0505357B1
(en)
|
1989-12-11 |
1999-03-10 |
Immunomedics, Inc. |
Method for antibody targeting of diagnostic or therapeutic agents
|
TW212184B
(es)
|
1990-04-02 |
1993-09-01 |
Takeda Pharm Industry Co Ltd |
|
JPH04228089A
(ja)
|
1990-05-15 |
1992-08-18 |
Kanegafuchi Chem Ind Co Ltd |
高カルシウム血症治療・予防剤
|
JPH05184383A
(ja)
|
1990-06-19 |
1993-07-27 |
Dainabotsuto Kk |
二重特異性抗体
|
GB9015198D0
(en)
|
1990-07-10 |
1990-08-29 |
Brien Caroline J O |
Binding substance
|
WO1992020791A1
(en)
|
1990-07-10 |
1992-11-26 |
Cambridge Antibody Technology Limited |
Methods for producing members of specific binding pairs
|
JPH05199894A
(ja)
|
1990-08-20 |
1993-08-10 |
Takeda Chem Ind Ltd |
二重特異性抗体および抗体含有薬剤
|
ES2108048T3
(es)
|
1990-08-29 |
1997-12-16 |
Genpharm Int |
Produccion y utilizacion de animales inferiores transgenicos capaces de producir anticuerpos heterologos.
|
WO1992019759A1
(en)
|
1991-04-25 |
1992-11-12 |
Chugai Seiyaku Kabushiki Kaisha |
Reconstituted human antibody against human interleukin 6 receptor
|
JPH04336051A
(ja)
|
1991-05-10 |
1992-11-24 |
Toshiba Corp |
超音波診断装置
|
JPH05304992A
(ja)
|
1991-06-20 |
1993-11-19 |
Takeda Chem Ind Ltd |
ハイブリッド・モノクローナル抗体および抗体含有薬剤
|
DK0605522T3
(da)
|
1991-09-23 |
2000-01-17 |
Medical Res Council |
Fremgangsmåde til fremstilling af humaniserede antistoffer
|
ATE297465T1
(de)
|
1991-11-25 |
2005-06-15 |
Enzon Inc |
Verfahren zur herstellung von multivalenten antigenbindenden proteinen
|
US6025165A
(en)
|
1991-11-25 |
2000-02-15 |
Enzon, Inc. |
Methods for producing multivalent antigen-binding proteins
|
ES2227512T3
(es)
|
1991-12-02 |
2005-04-01 |
Medical Research Council |
Produccion de anticuerpos contra auto-antigenos a partir de repertorios de segmentos de anticuerpos fijados en un fago.
|
CA2124967C
(en)
|
1991-12-17 |
2008-04-08 |
Nils Lonberg |
Transgenic non-human animals capable of producing heterologous antibodies
|
US5667988A
(en)
|
1992-01-27 |
1997-09-16 |
The Scripps Research Institute |
Methods for producing antibody libraries using universal or randomized immunoglobulin light chains
|
JPH05203652A
(ja)
|
1992-01-28 |
1993-08-10 |
Fuji Photo Film Co Ltd |
抗体酵素免疫分析法
|
JPH05213775A
(ja)
|
1992-02-05 |
1993-08-24 |
Otsuka Pharmaceut Co Ltd |
Bfa抗体
|
US6749853B1
(en)
|
1992-03-05 |
2004-06-15 |
Board Of Regents, The University Of Texas System |
Combined methods and compositions for coagulation and tumor treatment
|
JP3507073B2
(ja)
|
1992-03-24 |
2004-03-15 |
ケンブリッジ アンティボディー テクノロジー リミティド |
特異的結合対の成員の製造方法
|
US6129914A
(en)
|
1992-03-27 |
2000-10-10 |
Protein Design Labs, Inc. |
Bispecific antibody effective to treat B-cell lymphoma and cell line
|
US5744446A
(en)
|
1992-04-07 |
1998-04-28 |
Emory University |
Hybrid human/animal factor VIII
|
WO1993022332A2
(en)
|
1992-04-24 |
1993-11-11 |
Board Of Regents, The University Of Texas System |
Recombinant production of immunoglobulin-like domains in prokaryotic cells
|
CA2140638C
(en)
|
1992-07-24 |
2010-05-04 |
Raju Kucherlapati |
Generation of xenogeneic antibodies
|
ZA936260B
(en)
|
1992-09-09 |
1994-03-18 |
Smithkline Beecham Corp |
Novel antibodies for conferring passive immunity against infection by a pathogen in man
|
US5639641A
(en)
|
1992-09-09 |
1997-06-17 |
Immunogen Inc. |
Resurfacing of rodent antibodies
|
GB9313509D0
(en)
|
1993-06-30 |
1993-08-11 |
Medical Res Council |
Chemisynthetic libraries
|
WO1996011020A1
(fr)
|
1994-10-07 |
1996-04-18 |
Chugai Seiyaku Kabushiki Kaisha |
Medicament contre la polyarthrite rhumatoide contenant un antagoniste d'interleukine 6 comme principe actif
|
EP0729976A1
(en)
|
1993-11-19 |
1996-09-04 |
Chugai Seiyaku Kabushiki Kaisha |
Reconstituted human antibody against human medulloblastomatous cell
|
US6214613B1
(en)
|
1993-12-03 |
2001-04-10 |
Ashai Kasei Kogyo Kabushiki Kaisha |
Expression screening vector
|
EP0731842A1
(en)
|
1993-12-03 |
1996-09-18 |
Medical Research Council |
Recombinant binding proteins and peptides
|
JP3485266B2
(ja)
|
1994-05-20 |
2004-01-13 |
松下電器産業株式会社 |
プロセッサ
|
US5622701A
(en)
|
1994-06-14 |
1997-04-22 |
Protein Design Labs, Inc. |
Cross-reacting monoclonal antibodies specific for E- and P-selectin
|
EP0770628B9
(en)
|
1994-07-13 |
2007-02-28 |
Chugai Seiyaku Kabushiki Kaisha |
Reconstituted human antibody against human interleukin-8
|
AU3272695A
(en)
|
1994-08-12 |
1996-03-07 |
Immunomedics Inc. |
Immunoconjugates and humanized antibodies specific for b-cell lymphoma and leukemia cells
|
US6309636B1
(en)
|
1995-09-14 |
2001-10-30 |
Cancer Research Institute Of Contra Costa |
Recombinant peptides derived from the Mc3 anti-BA46 antibody, methods of use thereof, and methods of humanizing antibody peptides
|
WO1996012503A1
(fr)
|
1994-10-21 |
1996-05-02 |
Chugai Seiyaku Kabushiki Kaisha |
Remede contre des maladies provoquees par la production d'il-6
|
CA2207869A1
(en)
|
1994-12-02 |
1996-06-06 |
Chiron Corporation |
Method of promoting an immune response with a bispecific antibody
|
US6485943B2
(en)
|
1995-01-17 |
2002-11-26 |
The University Of Chicago |
Method for altering antibody light chain interactions
|
BR9604884A
(pt)
|
1995-02-28 |
1998-05-19 |
Procter & Gamble |
Preparação de produtos de bebida não carbonatada com estabilidade microbiana superior
|
US5731168A
(en)
|
1995-03-01 |
1998-03-24 |
Genentech, Inc. |
Method for making heteromultimeric polypeptides
|
CA2219361C
(en)
|
1995-04-27 |
2012-02-28 |
Abgenix, Inc. |
Human antibodies derived from immunized xenomice
|
EP0823941A4
(en)
|
1995-04-28 |
2001-09-19 |
Abgenix Inc |
HUMAN ANTIBODIES DERIVED FROM IMMUNIZED XENO MOUSES
|
CN1241944C
(zh)
|
1995-09-11 |
2006-02-15 |
协和发酵工业株式会社 |
抗人白介素-5受体α链的抗体
|
MA24512A1
(fr)
|
1996-01-17 |
1998-12-31 |
Univ Vermont And State Agrienl |
Procede pour la preparation d'agents anticoagulants utiles dans le traitement de la thrombose
|
SK1499A3
(en)
|
1996-07-19 |
1999-08-06 |
Amgen Inc |
Analogs of cationic proteins
|
BR9713294A
(pt)
|
1996-09-26 |
2000-10-17 |
Chugai Pharmaceutical Co Ltd |
"anticorpos contra proteìna relacionada a hormÈnio de paratiróide humano"
|
JP3587664B2
(ja)
|
1996-10-04 |
2004-11-10 |
中外製薬株式会社 |
再構成ヒト抗hm1.24抗体
|
UA76934C2
(en)
|
1996-10-04 |
2006-10-16 |
Chugai Pharmaceutical Co Ltd |
Reconstructed human anti-hm 1.24 antibody, coding dna, vector, host cell, method for production of reconstructed human antibody, pharmaceutical composition and drug for treating myeloma containing reconstructed human anti-hm 1.24 antibody
|
WO1998023289A1
(en)
|
1996-11-27 |
1998-06-04 |
The General Hospital Corporation |
MODULATION OF IgG BINDING TO FcRn
|
JPH10165184A
(ja)
|
1996-12-16 |
1998-06-23 |
Tosoh Corp |
抗体、遺伝子及びキメラ抗体の製法
|
US5990286A
(en)
|
1996-12-18 |
1999-11-23 |
Techniclone, Inc. |
Antibodies with reduced net positive charge
|
JP4228089B2
(ja)
|
1997-03-11 |
2009-02-25 |
株式会社ニコン |
過電流検知機構およびそれを用いた電子閃光装置
|
JPH10256223A
(ja)
|
1997-03-11 |
1998-09-25 |
Super Silicon Kenkyusho:Kk |
ウェーハ面取り部の枚葉処理装置
|
US6884879B1
(en)
|
1997-04-07 |
2005-04-26 |
Genentech, Inc. |
Anti-VEGF antibodies
|
US20070059302A1
(en)
|
1997-04-07 |
2007-03-15 |
Genentech, Inc. |
Anti-vegf antibodies
|
FR2761994B1
(fr)
|
1997-04-11 |
1999-06-18 |
Centre Nat Rech Scient |
Preparation de recepteurs membranaires a partir de baculovirus extracellulaires
|
US20030207346A1
(en)
|
1997-05-02 |
2003-11-06 |
William R. Arathoon |
Method for making multispecific antibodies having heteromultimeric and common components
|
US20020062010A1
(en)
|
1997-05-02 |
2002-05-23 |
Genentech, Inc. |
Method for making multispecific antibodies having heteromultimeric and common components
|
AU751659B2
(en)
|
1997-05-02 |
2002-08-22 |
Genentech Inc. |
A method for making multispecific antibodies having heteromultimeric and common components
|
DE19725586C2
(de)
|
1997-06-17 |
1999-06-24 |
Gsf Forschungszentrum Umwelt |
Verfahren zur Herstellung von Zellpräparaten zur Immunisierung mittels heterologer intakter bispezifischer und/oder trispezifischer Antikörper
|
US6207805B1
(en)
|
1997-07-18 |
2001-03-27 |
University Of Iowa Research Foundation |
Prostate cell surface antigen-specific antibodies
|
US6617156B1
(en)
|
1997-08-15 |
2003-09-09 |
Lynn A. Doucette-Stamm |
Nucleic acid and amino acid sequences relating to Enterococcus faecalis for diagnostics and therapeutics
|
US6342220B1
(en)
|
1997-08-25 |
2002-01-29 |
Genentech, Inc. |
Agonist antibodies
|
US7361336B1
(en)
|
1997-09-18 |
2008-04-22 |
Ivan Bergstein |
Methods of cancer therapy targeted against a cancer stem line
|
CN1277632A
(zh)
|
1997-10-03 |
2000-12-20 |
中外制药株式会社 |
天然人源化抗体
|
JPH11118775A
(ja)
|
1997-10-09 |
1999-04-30 |
Canon Inc |
超音波検査装置
|
US6528624B1
(en)
|
1998-04-02 |
2003-03-04 |
Genentech, Inc. |
Polypeptide variants
|
ES2364266T3
(es)
|
1998-04-03 |
2011-08-30 |
Chugai Seiyaku Kabushiki Kaisha |
Anticuerpo humanizado hacia el factor tisular humano (tf) y procedimiento para construir el anticuerpo humanizado.
|
PT1071700E
(pt)
|
1998-04-20 |
2010-04-23 |
Glycart Biotechnology Ag |
Modificação por glicosilação de anticorpos para melhorar a citotoxicidade celular dependente de anticorpos
|
GB9809951D0
(en)
|
1998-05-08 |
1998-07-08 |
Univ Cambridge Tech |
Binding molecules
|
JP3445153B2
(ja)
|
1998-06-04 |
2003-09-08 |
富士通株式会社 |
電話番号一時的使用装置及び方法
|
CA2341029A1
(en)
|
1998-08-17 |
2000-02-24 |
Abgenix, Inc. |
Generation of modified molecules with increased serum half-lives
|
WO2000018806A1
(de)
|
1998-09-25 |
2000-04-06 |
Horst Lindhofer |
Bispezifische und trispezifische antikörper, die spezifisch mit induzierbaren oberflächenantigenen als operationelle zielstrukturen reagieren
|
AU769125B2
(en)
|
1998-10-16 |
2004-01-15 |
Regents Of The University Of California, The |
Glypicans for the detection and treatment of human carcinoma
|
DE69942671D1
(de)
|
1998-12-01 |
2010-09-23 |
Facet Biotech Corp |
Humanisierte antikoerper gegen gamma-interferon
|
US7183387B1
(en)
|
1999-01-15 |
2007-02-27 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
US6737056B1
(en)
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
ES2694002T3
(es)
|
1999-01-15 |
2018-12-17 |
Genentech, Inc. |
Polipéptido que comprende una región Fc de IgG1 humana variante
|
US6972125B2
(en)
|
1999-02-12 |
2005-12-06 |
Genetics Institute, Llc |
Humanized immunoglobulin reactive with B7-2 and methods of treatment therewith
|
DK1156823T3
(da)
|
1999-02-12 |
2009-01-19 |
Scripps Research Inst |
Fremgangsmåder til behandling af tumorer og metastaser ved anvendelse af en kombination af anti-angiogene terapier og immunoterapier
|
PT1914244E
(pt)
|
1999-04-09 |
2013-07-26 |
Kyowa Hakko Kirin Co Ltd |
Processo para regular a actividade de moléculas funcionais sob o ponto de vista imunológico
|
SK782002A3
(en)
|
1999-07-21 |
2003-08-05 |
Lexigen Pharm Corp |
FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
WO2001013940A1
(fr)
|
1999-08-23 |
2001-03-01 |
Chugai Seiyaku Kabushiki Kaisha |
Potentialisateurs d'expression de l'antigene hm1.24
|
AT411997B
(de)
|
1999-09-14 |
2004-08-26 |
Baxter Ag |
Faktor ix/faktor ixa aktivierende antikörper und antikörper-derivate
|
JP3606132B2
(ja)
|
1999-10-14 |
2005-01-05 |
Jfeエンジニアリング株式会社 |
超音波探傷方法およびその装置
|
SE9903895D0
(sv)
|
1999-10-28 |
1999-10-28 |
Active Biotech Ab |
Novel compounds
|
AU2001266272B2
(en)
|
2000-05-03 |
2005-09-15 |
Medigene Ag |
Cationic diagnostic, imaging and therapeutic agents associated with activated vascular sites
|
US20020103345A1
(en)
|
2000-05-24 |
2002-08-01 |
Zhenping Zhu |
Bispecific immunoglobulin-like antigen binding proteins and method of production
|
GB0017635D0
(en)
|
2000-07-18 |
2000-09-06 |
Pharmacia & Upjohn Spa |
Antitumor combined therapy
|
JP2002048867A
(ja)
|
2000-08-07 |
2002-02-15 |
Mitsubishi Heavy Ind Ltd |
音響探査装置
|
DE60128817T2
(de)
|
2000-09-12 |
2008-02-07 |
Union Carbide Chemicals & Plastics Technology Corp., Danbury |
Polymerische mischungen enthaltend ethylenoxid-copolymere
|
CA2785941C
(en)
|
2000-10-06 |
2017-01-10 |
Kyowa Hakko Kirin Co., Ltd. |
Antibody composition-producing cell
|
WO2002040545A2
(en)
|
2000-11-17 |
2002-05-23 |
The Government Of The United States, As Represented By The Secretary Of The Department Of Health And Human Services |
Reduction of the nonspecific animal toxicity of immunotoxins by mutating the framework regions of the fv to lower the isoelectric point
|
US7361343B2
(en)
|
2003-01-21 |
2008-04-22 |
Arius Research Inc. |
Cytotoxicity mediation of cells evidencing surface expression of CD63
|
ES2649037T3
(es)
|
2000-12-12 |
2018-01-09 |
Medimmune, Llc |
Moléculas con semividas prolongadas, composiciones y usos de las mismas
|
WO2002079255A1
(en)
|
2001-04-02 |
2002-10-10 |
Idec Pharmaceuticals Corporation |
RECOMBINANT ANTIBODIES COEXPRESSED WITH GnTIII
|
EP1250023A1
(en)
|
2001-04-11 |
2002-10-16 |
Alcatel |
Provision of subscriber QoS guarantees to roaming subscribers
|
CN1294148C
(zh)
|
2001-04-11 |
2007-01-10 |
中国科学院遗传与发育生物学研究所 |
环状单链三特异抗体
|
IL158376A0
(en)
|
2001-04-13 |
2004-05-12 |
Biogen Inc |
Antibodies to vla-1
|
JP3642316B2
(ja)
|
2001-06-15 |
2005-04-27 |
日本電気株式会社 |
化学増幅レジスト用単量体、化学増幅レジスト用重合体、化学増幅レジスト組成物、パターン形成方法
|
JP4281869B2
(ja)
|
2001-06-22 |
2009-06-17 |
中外製薬株式会社 |
抗グリピカン3抗体を含む細胞増殖抑制剤
|
WO2004003019A2
(en)
|
2002-06-28 |
2004-01-08 |
Domantis Limited |
Immunoglobin single variant antigen-binding domains and dual-specific constructs
|
DE10136273A1
(de)
|
2001-07-25 |
2003-02-13 |
Sabine Debuschewitz |
Molekulare Marker beim hepatozellulären Karzinom
|
CN1555411A
(zh)
|
2001-08-03 |
2004-12-15 |
���迨�����\���ɷݹ�˾ |
抗体-依赖性细胞毒性增大的抗体糖基化变体
|
US20030049203A1
(en)
|
2001-08-31 |
2003-03-13 |
Elmaleh David R. |
Targeted nucleic acid constructs and uses related thereto
|
EP1432402B1
(en)
|
2001-10-03 |
2006-11-22 |
Celator Pharmaceuticals, Inc. |
Compositions for delivery of drug combinations
|
US7850990B2
(en)
|
2001-10-03 |
2010-12-14 |
Celator Pharmaceuticals, Inc. |
Compositions for delivery of drug combinations
|
EP1443961B1
(en)
|
2001-10-25 |
2009-05-06 |
Genentech, Inc. |
Glycoprotein compositions
|
DE10156482A1
(de)
|
2001-11-12 |
2003-05-28 |
Gundram Jung |
Bispezifisches Antikörper-Molekül
|
JP4087098B2
(ja)
|
2001-11-14 |
2008-05-14 |
株式会社東芝 |
超音波検査装置
|
CN100460872C
(zh)
|
2001-11-14 |
2009-02-11 |
株式会社东芝 |
超声波成像装置
|
JP3961359B2
(ja)
|
2002-07-18 |
2007-08-22 |
株式会社東芝 |
超音波画像化装置
|
JP2003157075A
(ja)
|
2001-11-22 |
2003-05-30 |
Kawai Musical Instr Mfg Co Ltd |
電子楽器のパラメータ入力装置
|
EP3960855A1
(en)
|
2001-12-28 |
2022-03-02 |
Chugai Seiyaku Kabushiki Kaisha |
Method for stabilizing proteins
|
US20030224397A1
(en)
|
2002-02-11 |
2003-12-04 |
Genentech, Inc. |
Antibody variants with faster antigen association rates
|
US20040002587A1
(en)
|
2002-02-20 |
2004-01-01 |
Watkins Jeffry D. |
Fc region variants
|
US8188231B2
(en)
|
2002-09-27 |
2012-05-29 |
Xencor, Inc. |
Optimized FC variants
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
US7317091B2
(en)
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
US8093357B2
(en)
|
2002-03-01 |
2012-01-10 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
WO2003074679A2
(en)
|
2002-03-01 |
2003-09-12 |
Xencor |
Antibody optimization
|
AU2003236018A1
(en)
|
2002-04-09 |
2003-10-20 |
Kyowa Hakko Kirin Co., Ltd. |
METHOD OF ENHANCING ACTIVITY OF ANTIBODY COMPOSITION OF BINDING TO FcGamma RECEPTOR IIIa
|
JP4386741B2
(ja)
|
2002-04-15 |
2009-12-16 |
中外製薬株式会社 |
scDbライブラリーの作成方法
|
WO2003091424A1
(fr)
|
2002-04-26 |
2003-11-06 |
Chugai Seiyaku Kabushiki Kaisha |
Procede de criblage d'un anticorps agoniste
|
WO2003100429A2
(en)
|
2002-05-23 |
2003-12-04 |
Sunnybrook And Women's College Health Sciences Centre |
Diagnosis of hepatocellular carcinoma
|
US20060088899A1
(en)
|
2002-05-31 |
2006-04-27 |
Alvarez Vernon L |
Combination chemotherapy with chlorotoxin
|
JP2004086862A
(ja)
|
2002-05-31 |
2004-03-18 |
Celestar Lexico-Sciences Inc |
タンパク質相互作用情報処理装置、タンパク質相互作用情報処理方法、プログラム、および、記録媒体
|
US20050130224A1
(en)
|
2002-05-31 |
2005-06-16 |
Celestar Lexico- Sciences, Inc. |
Interaction predicting device
|
ES2442615T5
(es)
|
2002-07-18 |
2023-03-16 |
Merus Nv |
Producción recombinante de mezclas de anticuerpos
|
WO2004016740A2
(en)
|
2002-08-15 |
2004-02-26 |
Epitomics, Inc. |
Humanized rabbit antibodies
|
JP4406607B2
(ja)
|
2002-08-26 |
2010-02-03 |
オンコセラピー・サイエンス株式会社 |
ペプチド及びこれを含む医薬
|
WO2004023145A1
(ja)
|
2002-09-04 |
2004-03-18 |
Perseus Proteomics Inc. |
Gpc3の検出による癌の診断方法
|
AU2002338020A1
(en)
|
2002-09-04 |
2004-03-29 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody against blood-solubilized n-terminal peptide in gpc3
|
AU2002328429A1
(en)
|
2002-09-04 |
2004-03-29 |
Chugai Seiyaku Kabushiki Kaisha |
CONSTRUCTION OF ANTIBODY USING MRL/lpr MOUSE
|
DK2345671T3
(en)
|
2002-09-27 |
2016-02-15 |
Xencor Inc |
Optimized Fc variants and methods for their formation
|
US20060235208A1
(en)
|
2002-09-27 |
2006-10-19 |
Xencor, Inc. |
Fc variants with optimized properties
|
AU2003286467B2
(en)
|
2002-10-15 |
2009-10-01 |
Abbvie Biotherapeutics Inc. |
Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
|
EP2330130B1
(en)
|
2002-10-17 |
2014-08-27 |
Genmab A/S |
Human monoclonal antibodies against CD20
|
US8337841B2
(en)
|
2003-01-21 |
2012-12-25 |
Chugai Seiyaku Kabushiki Kaisha |
Methods of screening for antibody light chains
|
JP2006517109A
(ja)
|
2003-02-07 |
2006-07-20 |
プロテイン デザイン ラブス インコーポレイテッド |
アンフィレグリン抗体ならびに癌および乾癬を処置するためのその使用
|
US20090010920A1
(en)
|
2003-03-03 |
2009-01-08 |
Xencor, Inc. |
Fc Variants Having Decreased Affinity for FcyRIIb
|
US8388955B2
(en)
|
2003-03-03 |
2013-03-05 |
Xencor, Inc. |
Fc variants
|
US20060228694A1
(en)
|
2003-04-02 |
2006-10-12 |
Janoff Andrew S |
Methods to individualize combination therapy
|
GB2400851B
(en)
|
2003-04-25 |
2004-12-15 |
Bioinvent Int Ab |
Identifying binding of a polypeptide to a polypeptide target
|
GB2401040A
(en)
|
2003-04-28 |
2004-11-03 |
Chugai Pharmaceutical Co Ltd |
Method for treating interleukin-6 related diseases
|
RU2337107C2
(ru)
|
2003-05-02 |
2008-10-27 |
Ксенкор, Инк. |
ОПТИМИЗИРОВАННЫЕ Fc-ВАРИАНТЫ, ИМЕЮЩИЕ ИЗМЕНЕННОЕ СВЯЗЫВАНИЕ С FcγR, И СПОСОБЫ ИХ ПОЛУЧЕНИЯ
|
US6921978B2
(en)
|
2003-05-08 |
2005-07-26 |
International Business Machines Corporation |
Method to generate porous organic dielectric
|
ME00425B
(me)
|
2003-05-30 |
2011-10-10 |
Genentech Inc |
Liječenje sa anti-vegf antitijelima
|
PT2272868E
(pt)
|
2003-06-05 |
2015-07-07 |
Genentech Inc |
Terapêutica de combinação para distúrbios de células b
|
US8597911B2
(en)
|
2003-06-11 |
2013-12-03 |
Chugai Seiyaku Kabushiki Kaisha |
Process for producing antibodies
|
JP2005053541A
(ja)
|
2003-08-05 |
2005-03-03 |
Toppan Printing Co Ltd |
紙容器用積層材料及びそれを用いた紙容器
|
WO2005023301A1
(ja)
|
2003-09-04 |
2005-03-17 |
Chugai Seiyaku Kabushiki Kaisha |
胆管癌治療剤および検出薬
|
US7297336B2
(en)
|
2003-09-12 |
2007-11-20 |
Baxter International Inc. |
Factor IXa specific antibodies displaying factor VIIIa like activity
|
WO2005035753A1
(ja)
|
2003-10-10 |
2005-04-21 |
Chugai Seiyaku Kabushiki Kaisha |
機能蛋白質を代替する二重特異性抗体
|
WO2005035754A1
(ja)
|
2003-10-14 |
2005-04-21 |
Chugai Seiyaku Kabushiki Kaisha |
機能蛋白質を代替する二重特異性抗体
|
EP1697415A1
(en)
|
2003-11-12 |
2006-09-06 |
Biogen Idec MA Inc. |
NEONATAL Fc RECEPTOR (FcRn)-BINDING POLYPEPTIDE VARIANTS, DIMERIC Fc BINDING PROTEINS AND METHODS RELATED THERETO
|
WO2005063815A2
(en)
|
2003-11-12 |
2005-07-14 |
Biogen Idec Ma Inc. |
Fcϝ receptor-binding polypeptide variants and methods related thereto
|
NZ547157A
(en)
|
2003-12-10 |
2009-07-31 |
Medarex Inc |
Interferon Alpha Antibodies and their uses
|
CA2550996A1
(en)
|
2003-12-22 |
2005-07-14 |
Centocor, Inc. |
Methods for generating multimeric molecules
|
US20050266425A1
(en)
|
2003-12-31 |
2005-12-01 |
Vaccinex, Inc. |
Methods for producing and identifying multispecific antibodies
|
DK2177537T3
(da)
|
2004-01-09 |
2011-12-12 |
Pfizer |
Antistoffer til MAdCAM
|
ITBO20040008U1
(it)
|
2004-02-03 |
2004-05-03 |
Tonazzi S R L |
Macchina per il riempimento e la chiusura di tubetti
|
JP4223981B2
(ja)
|
2004-03-24 |
2009-02-12 |
学校法人東海大学 |
ホルムアルデヒド検知材料およびその製造方法
|
EP1737890A2
(en)
|
2004-03-24 |
2007-01-03 |
Xencor, Inc. |
Immunoglobulin variants outside the fc region
|
WO2005112564A2
(en)
|
2004-04-15 |
2005-12-01 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Germline and sequence variants of humanized antibodies and methods of making and using them
|
JP4658926B2
(ja)
|
2004-04-28 |
2011-03-23 |
株式会社ペルセウスプロテオミクス |
肝癌治療後の再発予測判定薬
|
BRPI0511782B8
(pt)
|
2004-06-03 |
2021-05-25 |
Novimmune Sa |
anticorpos anti-cd3, uso e método de produção dos mesmos, composição farmacêutica, molécula de ácido nucleico isolada e vetor
|
WO2005117980A1
(en)
|
2004-06-04 |
2005-12-15 |
Pfizer Products Inc. |
Method for treating abnormal cell growth
|
KR100620554B1
(ko)
|
2004-06-05 |
2006-09-06 |
한국생명공학연구원 |
Tag-72에 대한 인간화 항체
|
AR049390A1
(es)
|
2004-06-09 |
2006-07-26 |
Wyeth Corp |
Anticuerpos contra la interleuquina-13 humana y usos de los mismos
|
JP2008504289A
(ja)
|
2004-06-25 |
2008-02-14 |
メディミューン,インコーポレーテッド |
部位特異的突然変異誘発による哺乳動物細胞における組換え抗体の産生の増加
|
DE102004032634A1
(de)
|
2004-07-06 |
2006-02-16 |
Sms Demag Ag |
Verfahren und Einrichtung zum Messen und Regeln der Planheit und/oder der Bandspannungen eines Edelstahlbandes oder einer Edelstahlfolie beim Kaltwalzen in einem Vielwalzengerüst, insbesondere in einem 20-Walzen-Sendizimir-Walzwerk
|
NZ579543A
(en)
|
2004-07-09 |
2011-07-29 |
Chugai Pharmaceutical Co Ltd |
Anti-glypican 3 antibody
|
JP4331227B2
(ja)
|
2004-07-09 |
2009-09-16 |
中外製薬株式会社 |
抗グリピカン3抗体
|
EP2471813B1
(en)
|
2004-07-15 |
2014-12-31 |
Xencor, Inc. |
Optimized Fc variants
|
DK1776384T3
(da)
|
2004-08-04 |
2013-09-02 |
Mentrik Biotech Llc |
VARIANT-Fc-REGIONER
|
CA2577370A1
(en)
|
2004-08-16 |
2006-03-02 |
Medimmune, Inc. |
Integrin antagonists with enhanced antibody dependent cell-mediated cytotoxicity activity
|
KR20130103580A
(ko)
|
2004-08-24 |
2013-09-23 |
추가이 세이야쿠 가부시키가이샤 |
항 글리피칸 3 항체를 이용한 어쥬번트 요법
|
WO2006028936A2
(en)
|
2004-09-02 |
2006-03-16 |
Genentech, Inc. |
Heteromultimeric molecules
|
US7572456B2
(en)
|
2004-09-13 |
2009-08-11 |
Macrogenics, Inc. |
Humanized antibodies against West Nile Virus and therapeutic and prophylactic uses thereof
|
US20080233131A1
(en)
|
2004-09-14 |
2008-09-25 |
Richard John Stebbings |
Vaccine
|
US20060074225A1
(en)
|
2004-09-14 |
2006-04-06 |
Xencor, Inc. |
Monomeric immunoglobulin Fc domains
|
US7563443B2
(en)
|
2004-09-17 |
2009-07-21 |
Domantis Limited |
Monovalent anti-CD40L antibody polypeptides and compositions thereof
|
NZ554940A
(en)
|
2004-10-26 |
2010-04-30 |
Chugai Pharmaceutical Co Ltd |
Anti-glypican 3 antibody having modified sugar chain
|
US7462697B2
(en)
|
2004-11-08 |
2008-12-09 |
Epitomics, Inc. |
Methods for antibody engineering
|
PE20061401A1
(es)
|
2004-12-15 |
2006-12-23 |
Neuralab Ltd |
ANTICUERPOS Aß PARA MEJORAR LA COGNICION
|
JPWO2006067847A1
(ja)
|
2004-12-22 |
2008-06-12 |
中外製薬株式会社 |
フコーストランスポーターの機能が阻害された細胞を用いた抗体の作製方法
|
ES2408704T3
(es)
|
2005-01-05 |
2013-06-21 |
Biogen Idec Ma Inc. |
Moléculas de unión a Cripto
|
CA2595169A1
(en)
|
2005-01-12 |
2006-07-20 |
Xencor, Inc. |
Antibodies and fc fusion proteins with altered immunogenicity
|
CA2600929A1
(en)
|
2005-03-04 |
2006-09-14 |
Biogen Idec Ma Inc. |
Methods of humanizing immunoglobulin variable regions through rational modification of complementarity determining residues
|
WO2006106905A1
(ja)
|
2005-03-31 |
2006-10-12 |
Chugai Seiyaku Kabushiki Kaisha |
会合制御によるポリペプチド製造方法
|
US9493569B2
(en)
|
2005-03-31 |
2016-11-15 |
Chugai Seiyaku Kabushiki Kaisha |
Structural isomers of sc(Fv)2
|
AU2006230413B8
(en)
|
2005-03-31 |
2011-01-20 |
Xencor, Inc |
Fc variants with optimized properties
|
CA2957144C
(en)
|
2005-04-08 |
2020-06-02 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody substituting for function of blood coagulation factor viii
|
EP2221316A1
(en)
|
2005-05-05 |
2010-08-25 |
Duke University |
Anti-CD19 antibody therapy for autoimmune disease
|
AU2006256041B2
(en)
|
2005-06-10 |
2012-03-29 |
Chugai Seiyaku Kabushiki Kaisha |
Stabilizer for protein preparation comprising meglumine and use thereof
|
US20090028854A1
(en)
|
2005-06-10 |
2009-01-29 |
Chugai Seiyaku Kabushiki Kaisha |
sc(Fv)2 SITE-DIRECTED MUTANT
|
CA2614181A1
(en)
|
2005-07-01 |
2007-01-11 |
Medimmune, Inc. |
An integrated approach for generating multidomain protein therapeutics
|
US8299252B2
(en)
|
2005-08-05 |
2012-10-30 |
Chugai Seiyaku Kabushiki Kaisha |
Pyrazolopyridine and pyrrolopyridine multikinase inhibitors
|
CN103450359B
(zh)
|
2005-08-19 |
2018-07-24 |
惠氏有限责任公司 |
抗gdf-8的拮抗剂抗体以及在als和其他gdf-8-相关病症治疗中的用途
|
WO2007030531A2
(en)
|
2005-09-06 |
2007-03-15 |
Molecular Image Inc. |
Reagents for testing and molecular imaging of liver cancer
|
JP2007093274A
(ja)
|
2005-09-27 |
2007-04-12 |
Perseus Proteomics Inc |
癌の診断方法および治療薬
|
US20070087005A1
(en)
|
2005-10-14 |
2007-04-19 |
Lazar Gregory A |
Anti-glypican-3 antibody
|
CA2627873A1
(en)
|
2005-10-31 |
2007-05-10 |
Scott Wilhelm |
Treatment of cancer with sorafenib
|
US20070185069A1
(en)
|
2005-11-14 |
2007-08-09 |
Plum Stacy M |
Anti-angiogenic activity of 2-methoxyestradiol in combination with anti-cancer agents
|
WO2007060411A1
(en)
|
2005-11-24 |
2007-05-31 |
Ucb Pharma S.A. |
Anti-tnf alpha antibodies which selectively inhibit tnf alpha signalling through the p55r
|
WO2007059782A1
(en)
|
2005-11-28 |
2007-05-31 |
Genmab A/S |
Recombinant monovalent antibodies and methods for production thereof
|
US7723043B2
(en)
|
2006-01-04 |
2010-05-25 |
Picobella, Lp |
Methods for screening for prostate cancer
|
JP5133071B2
(ja)
|
2006-02-09 |
2013-01-30 |
第一三共株式会社 |
抗癌医薬組成物
|
EP1820513A1
(en)
|
2006-02-15 |
2007-08-22 |
Trion Pharma Gmbh |
Destruction of tumor cells expressing low to medium levels of tumor associated target antigens by trifunctional bispecific antibodies
|
TW200745163A
(en)
|
2006-02-17 |
2007-12-16 |
Syntonix Pharmaceuticals Inc |
Peptides that block the binding of IgG to FcRn
|
WO2007099988A1
(ja)
|
2006-02-28 |
2007-09-07 |
Kyowa Hakko Kogyo Co., Ltd. |
α-1,6-フコシルトランスフェラーゼ変異体とその用途
|
JP2007256063A
(ja)
|
2006-03-23 |
2007-10-04 |
Seiko Epson Corp |
表示装置、および、電子機器
|
EP1999154B1
(en)
|
2006-03-24 |
2012-10-24 |
Merck Patent GmbH |
Engineered heterodimeric protein domains
|
US9670269B2
(en)
|
2006-03-31 |
2017-06-06 |
Chugai Seiyaku Kabushiki Kaisha |
Methods of modifying antibodies for purification of bispecific antibodies
|
ES2568436T3
(es)
|
2006-03-31 |
2016-04-29 |
Chugai Seiyaku Kabushiki Kaisha |
Procedimiento para controlar la farmacocinética en sangre de anticuerpos
|
WO2007137170A2
(en)
|
2006-05-20 |
2007-11-29 |
Seattle Genetics, Inc. |
Anti-glypican-3 antibody drug conjugates
|
CA2653387A1
(en)
|
2006-06-06 |
2007-12-21 |
Tolerrx, Inc. |
Administration of anti-cd3 antibodies in the treatment of autoimmune diseases
|
ES2429407T3
(es)
|
2006-06-08 |
2013-11-14 |
Chugai Seiyaku Kabushiki Kaisha |
Agente preventivo o remedio para enfermedades inflamatorias
|
JP2009541275A
(ja)
|
2006-06-22 |
2009-11-26 |
ノボ・ノルデイスク・エー/エス |
二重特異性抗体の生産
|
GB2440721A
(en)
|
2006-08-11 |
2008-02-13 |
Univ Cambridge Tech |
Composite biomaterial formed by cooling a fluid composition on a porous solid and removing solidified crystals of the liquid carrier
|
JP4463793B2
(ja)
|
2006-10-10 |
2010-05-19 |
浜松ホトニクス株式会社 |
光検出装置
|
US20100034194A1
(en)
|
2006-10-11 |
2010-02-11 |
Siemens Communications Inc. |
Eliminating unreachable subscribers in voice-over-ip networks
|
JPWO2008090960A1
(ja)
|
2007-01-24 |
2010-05-20 |
協和発酵キリン株式会社 |
ガングリオシドgm2に特異的に結合する遺伝子組換え抗体組成物
|
MX2009009912A
(es)
*
|
2007-03-27 |
2010-01-18 |
Sea Lane Biotechnologies Llc |
Constructos y colecciones que comprenden secuencias de cadena ligera sustitutas de anticuerpos.
|
WO2008119353A1
(en)
|
2007-03-29 |
2008-10-09 |
Genmab A/S |
Bispecific antibodies and methods for production thereof
|
JP6071165B2
(ja)
|
2007-05-31 |
2017-02-01 |
ゲンマブ エー/エス |
安定なIgG4抗体
|
ES2540854T3
(es)
|
2007-06-29 |
2015-07-14 |
Merck Sharp & Dohme Corp. |
Usos de antagonistas MDL-1
|
US8680247B2
(en)
|
2007-07-17 |
2014-03-25 |
Medarex, L.L.C. |
Monoclonal antibodies against glypican-3
|
SG10201605394SA
(en)
|
2007-09-26 |
2016-08-30 |
Chugai Pharmaceutical Co Ltd |
Modified Antibody Constant Region
|
EP3689912A1
(en)
|
2007-09-26 |
2020-08-05 |
Chugai Seiyaku Kabushiki Kaisha |
Method of modifying isoelectric point of antibody via amino acid substitution in cdr
|
CN101939425B
(zh)
|
2007-09-26 |
2014-05-14 |
中外制药株式会社 |
抗il-6受体抗体
|
BRPI0817637A2
(pt)
|
2007-09-28 |
2015-09-08 |
Chugai Pharmaceutical Co Ltd |
anticorpo anti-glipican-3 tendo cinéticas aperfeiçoadas no plasma
|
EP2203180B1
(en)
|
2007-10-22 |
2012-11-21 |
Merck Serono S.A. |
Single ifn-beta fused to a mutated igg fc fragment
|
US8242247B2
(en)
|
2007-12-21 |
2012-08-14 |
Hoffmann-La Roche Inc. |
Bivalent, bispecific antibodies
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
WO2009089004A1
(en)
|
2008-01-07 |
2009-07-16 |
Amgen Inc. |
Method for making antibody fc-heterodimeric molecules using electrostatic steering effects
|
US8663929B2
(en)
|
2008-03-17 |
2014-03-04 |
University Of Miyazaki |
Method for detection of liver cancer cell using anti-glypican-3 antibody
|
AU2009228158B2
(en)
|
2008-03-27 |
2014-02-27 |
Zymogenetics, Inc. |
Compositions and methods for inhibiting PDGFRbeta and VEGF-A
|
CL2009000647A1
(es)
|
2008-04-04 |
2010-06-04 |
Chugai Pharmaceutical Co Ltd |
Composicion farmaceutica para tratar o prevenir cancer hepatico que comprende una combinacion de un agente quimioterapeutico y un anticuerpo anti-glipicano 3; agente para atenuar un efecto secundario que comprende dicho anticuerpo; metodo para tratar o prevenir un cancer hepatico de un sujeto.
|
EP4238993A3
(en)
|
2008-04-11 |
2023-11-29 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly
|
CN101377506A
(zh)
|
2008-04-16 |
2009-03-04 |
北京科美东雅生物技术有限公司 |
磷脂酰肌醇蛋白聚糖-3化学发光免疫分析测定试剂盒及其制备方法
|
CA2722466A1
(en)
|
2008-04-29 |
2009-11-05 |
Tariq Ghayur |
Dual variable domain immunoglobulins and uses thereof
|
CA2725666A1
(en)
|
2008-06-03 |
2009-12-10 |
Abbott Laboratories |
Dual variable domain immunoglobulins and uses thereof
|
DE102008042377A1
(de)
|
2008-09-25 |
2010-04-01 |
Robert Bosch Gmbh |
Audioverstärker mit Lastanpassung sowie Verfahren zur Lastanpassung des Audioverstärkers
|
WO2010034441A1
(en)
|
2008-09-26 |
2010-04-01 |
F. Hoffmann-La Roche Ag |
Bispecific anti-egfr/anti-igf-1r antibodies
|
TWI440469B
(zh)
|
2008-09-26 |
2014-06-11 |
Chugai Pharmaceutical Co Ltd |
Improved antibody molecules
|
EP2356150A2
(en)
*
|
2008-10-10 |
2011-08-17 |
Emergent Product Development Seattle, LLC |
Tcr complex immunotherapeutics
|
DE202008016028U1
(de)
|
2008-12-04 |
2010-04-15 |
Melitta Haushaltsprodukte Gmbh & Co. Kg |
Behälter zur Aufbewahrung von Gegenständen
|
US20120100140A1
(en)
|
2009-01-23 |
2012-04-26 |
Biogen Idec Ma Inc. |
Stabilized fc polypeptides with reduced effector function and methods of use
|
NZ594514A
(en)
|
2009-03-05 |
2013-06-28 |
Abbott Lab |
Interleukin-17 BINDING PROTEINS
|
US9228017B2
(en)
|
2009-03-19 |
2016-01-05 |
Chugai Seiyaku Kabushiki Kaisha |
Antibody constant region variant
|
JP5787446B2
(ja)
|
2009-03-19 |
2015-09-30 |
中外製薬株式会社 |
抗体定常領域改変体
|
EP2233500A1
(en)
|
2009-03-20 |
2010-09-29 |
LFB Biotechnologies |
Optimized Fc variants
|
CN102471380B
(zh)
|
2009-04-01 |
2015-01-14 |
霍夫曼-拉罗奇有限公司 |
抗FcRH5抗体和免疫偶联物及使用方法
|
KR101456326B1
(ko)
|
2009-04-07 |
2014-11-12 |
로슈 글리카트 아게 |
3가, 이중특이적 항체
|
JP2012525149A
(ja)
|
2009-04-27 |
2012-10-22 |
オンコメッド ファーマシューティカルズ インコーポレイテッド |
ヘテロ多量体分子を作製するための方法
|
PL2975051T3
(pl)
|
2009-06-26 |
2021-09-20 |
Regeneron Pharmaceuticals, Inc. |
Wyizolowane z łatwością dwuswoiste przeciwciała o formacie natywnej immunoglobuliny
|
TWI465250B
(zh)
|
2009-08-29 |
2014-12-21 |
Abbvie Inc |
治療用之dll4結合蛋白質
|
US10053513B2
(en)
|
2009-11-30 |
2018-08-21 |
Janssen Biotech, Inc. |
Antibody Fc mutants with ablated effector functions
|
JP2011118775A
(ja)
|
2009-12-04 |
2011-06-16 |
Sony Corp |
検索装置、検索方法、及び、プログラム
|
RU2606264C2
(ru)
|
2009-12-25 |
2017-01-10 |
Чугаи Сеияку Кабушики Каиша |
Способ полипептидной модификации для очистки полипептидных мультимеров
|
EP2543727B1
(en)
|
2010-03-02 |
2016-08-31 |
Kyowa Hakko Kirin Co., Ltd. |
Modified antibody composition
|
CN102844332B
(zh)
|
2010-03-11 |
2015-08-19 |
瑞纳神经科学公司 |
呈pH依赖性抗原结合的抗体
|
TWI667257B
(zh)
|
2010-03-30 |
2019-08-01 |
中外製藥股份有限公司 |
促進抗原消失之具有經修飾的FcRn親和力之抗體
|
SG184427A1
(en)
|
2010-04-20 |
2012-11-29 |
Genmab As |
Heterodimeric antibody fc-containing proteins and methods for production thereof
|
RU2624027C2
(ru)
|
2010-04-23 |
2017-06-30 |
Дженентек, Инк. |
Получение гетеромультимерных белков
|
WO2011143545A1
(en)
|
2010-05-14 |
2011-11-17 |
Rinat Neuroscience Corporation |
Heterodimeric proteins and methods for producing and purifying them
|
WO2011147986A1
(en)
|
2010-05-27 |
2011-12-01 |
Genmab A/S |
Monoclonal antibodies against her2
|
WO2012020096A1
(en)
|
2010-08-13 |
2012-02-16 |
Medimmune Limited |
Monomeric polypeptides comprising variant fc regions and methods of use
|
JP6167040B2
(ja)
|
2010-11-05 |
2017-07-19 |
ザイムワークス,インコーポレイテッド |
Fcドメイン中に突然変異を有する、安定したヘテロ二量体抗体の設計
|
BR112013013311A2
(pt)
|
2010-11-30 |
2017-09-19 |
Chugai Pharmaceutical Co Ltd |
agente terapêutico de indução de citotoxicidade
|
KR102147548B1
(ko)
|
2011-02-25 |
2020-08-24 |
추가이 세이야쿠 가부시키가이샤 |
FcγRIIb 특이적 Fc 항체
|
EP3070104B1
(en)
|
2011-04-19 |
2017-12-27 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
Human monoclonal antibodies specific for glypican-3 and use thereof
|
TW201817745A
(zh)
|
2011-09-30 |
2018-05-16 |
日商中外製藥股份有限公司 |
具有促進抗原清除之FcRn結合域的治療性抗原結合分子
|
JP6322411B2
(ja)
|
2011-09-30 |
2018-05-09 |
中外製薬株式会社 |
複数の生理活性を有する抗原の消失を促進する抗原結合分子
|
LT2771364T
(lt)
|
2011-10-27 |
2019-09-10 |
Genmab A/S |
Heterodimerinių baltymų gamyba
|
US11851476B2
(en)
|
2011-10-31 |
2023-12-26 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule having regulated conjugation between heavy-chain and light-chain
|
PL2773671T3
(pl)
|
2011-11-04 |
2022-01-24 |
Zymeworks Inc. |
Projekt stabilnego przeciwciała heterodimerycznego z mutacjami w domenie fc
|
CN113480639A
(zh)
|
2012-02-09 |
2021-10-08 |
中外制药株式会社 |
抗体的Fc区变异体
|
GB201203051D0
(en)
|
2012-02-22 |
2012-04-04 |
Ucb Pharma Sa |
Biological products
|
BR112014018374A8
(pt)
|
2012-03-02 |
2017-07-11 |
Roche Glycart Ag |
Método para predizer a resposta d eum paciente com câncer, kit, anticorpo, método para o tratamento do câncer e composição farmacêutica
|
NZ630551A
(en)
|
2012-04-20 |
2017-11-24 |
Merus Nv |
Methods and means for the production of ig-like molecules
|
CA2870545A1
(en)
*
|
2012-04-20 |
2013-10-24 |
Emergent Product Development Seattle, Llc |
Cd3 binding polypeptides
|
JP6494507B2
(ja)
*
|
2012-06-01 |
2019-04-03 |
ザ ユナイテッド ステイツ オブ アメリカ, アズ リプレゼンテッド バイ ザ セクレタリー, デパートメント オブ ヘルス アンド ヒューマン サービシーズ |
グリピカン−3に対する高親和性モノクローナル抗体およびその使用
|
NZ704771A
(en)
|
2012-08-13 |
2018-02-23 |
Regeneron Pharma |
Anti-pcsk9 antibodies with ph-dependent binding characteristics
|
NZ630563A
(en)
*
|
2012-09-27 |
2017-04-28 |
Merus Nv |
Bispecific igg antibodies as t cell engagers
|
US9714291B2
(en)
|
2012-10-05 |
2017-07-25 |
Kyowa Hakko Kirin Co., Ltd |
Heterodimer protein composition
|
EP2914634B1
(en)
|
2012-11-02 |
2017-12-06 |
Zymeworks Inc. |
Crystal structures of heterodimeric fc domains
|
CN103833852A
(zh)
*
|
2012-11-23 |
2014-06-04 |
上海市肿瘤研究所 |
针对磷脂酰肌醇蛋白多糖-3和t细胞抗原的双特异性抗体
|
TWI693073B
(zh)
|
2012-12-21 |
2020-05-11 |
日商中外製藥股份有限公司 |
對gpc3標的治療劑療法為有效之患者投與的gpc3標的治療劑
|
KR102441231B1
(ko)
|
2013-09-27 |
2022-09-06 |
추가이 세이야쿠 가부시키가이샤 |
폴리펩티드 이종 다량체의 제조방법
|
WO2015046554A1
(ja)
|
2013-09-30 |
2015-04-02 |
中外製薬株式会社 |
改変されたヘルパーファージを用いて抗原結合分子を作製する方法
|
TWI726842B
(zh)
|
2014-04-07 |
2021-05-11 |
日商中外製藥股份有限公司 |
免疫活化抗原結合分子
|
EP3141603A4
(en)
|
2014-05-08 |
2017-12-27 |
Chugai Seiyaku Kabushiki Kaisha |
Gpc3-targeted therapeutic agent for administration to patients for whom gpc3-targeted therapeutic agent therapy is effective
|
MX2016014434A
(es)
|
2014-05-13 |
2017-02-23 |
Chugai Pharmaceutical Co Ltd |
Molecula de union a antigeno redirigida a celulas t para celulas que tienen funcion de inmunosupresion.
|
MA40764A
(fr)
*
|
2014-09-26 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Agent thérapeutique induisant une cytotoxicité
|
SG11201607165YA
(en)
|
2014-12-19 |
2016-09-29 |
Chugai Pharmaceutical Co Ltd |
Anti-c5 antibodies and methods of use
|
TWI808330B
(zh)
|
2014-12-19 |
2023-07-11 |
日商中外製藥股份有限公司 |
抗肌抑素之抗體、含變異Fc區域之多胜肽及使用方法
|
TW202248212A
(zh)
|
2015-02-05 |
2022-12-16 |
日商中外製藥股份有限公司 |
包含離子濃度依賴之抗原結合域的抗體、Fc區變體、IL-8結合抗體與其用途
|
EP3279216A4
(en)
|
2015-04-01 |
2019-06-19 |
Chugai Seiyaku Kabushiki Kaisha |
PROCESS FOR PREPARING POLYPEPTIDE HETERO OLIGOMER
|
MY196747A
(en)
|
2016-03-14 |
2023-05-03 |
Chugai Pharmaceutical Co Ltd |
Cell injury inducing therapeutic drug for use in cancer therapy
|
AU2017233658B2
(en)
*
|
2016-03-14 |
2023-09-21 |
Chugai Seiyaku Kabushiki Kaisha |
Cell injury inducing therapeutic drug for use in cancer therapy
|