PE20160651A1 - Proteinas de union a il-17 - Google Patents

Proteinas de union a il-17

Info

Publication number
PE20160651A1
PE20160651A1 PE2016000576A PE2016000576A PE20160651A1 PE 20160651 A1 PE20160651 A1 PE 20160651A1 PE 2016000576 A PE2016000576 A PE 2016000576A PE 2016000576 A PE2016000576 A PE 2016000576A PE 20160651 A1 PE20160651 A1 PE 20160651A1
Authority
PE
Peru
Prior art keywords
cdr
seq
agent
refers
binding protein
Prior art date
Application number
PE2016000576A
Other languages
English (en)
Inventor
Suju Zhong
Edit Tarcsa
Anca Clabbers
Craig Wallace
Shaughn H Bryant
Mary R Leddy
Chung-Ming Hsieh
John E Memmott
Bradford L Mcrae
Yuliya Kutskova
Margaret Hugunin
Anwar Murtaza
Jennifer M Perez
Original Assignee
Abbvie Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42710240&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20160651(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbvie Inc filed Critical Abbvie Inc
Publication of PE20160651A1 publication Critical patent/PE20160651A1/es

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    • C07—ORGANIC CHEMISTRY
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    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C—CHEMISTRY; METALLURGY
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Abstract

SE REFIERE A UNA PROTEINA DE UNION QUE SE UNE A IL-17 HUMANA QUE COMPRENDE UN DOMINIO DE UNION AL ANTIGENO QUE COMPRENDE AL MENOS UNA CDR QUE COMPRENDE UNA SECUENCIA DE AMINOACIDOS TAL COMO CDR-H1 DE SEQ ID Nº 919, CDR-H2 DE SEQ ID Nº 920, CDR-H3 DE SEQ ID Nº 921, CDR-L1 DE SEQ ID Nº 922, CDR-L2 DE SEQ ID Nº 923 Y CDR-L3 DE SEQ ID Nº 924. TAMBIEN SE REFIERE A UN CONJUGADO DE PROTEINA DE UNION A IL-17 QUE COMPRENDE UNA MOLECULA DE INMUNOADHESION, UN AGENTE PARA DETERMINAR IMAGENES TAL COMO UNA MARCA RADIOACTIVA, UNA ENZIMA, UNA MARCA FLUORESCENTE, UN AGENTE TERAPEUTICO O UN AGENTE CITOTOXICO TAL COMO UN ANTIMETABOLITO, UN AGENTE ALQUILANTE, UNA CITOQUINA, ENTRE OTROS. DICHA PROTEINA DE UNION ES UTIL EN EL TRATAMIENTO DE ASMA, ENFERMEDAD PULMONAR OBSTRUCTIVA CRONICA, ENTRE OTROS
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