PE20021017A1 - Composicion parenteral reconstituible - Google Patents

Composicion parenteral reconstituible

Info

Publication number
PE20021017A1
PE20021017A1 PE2002000258A PE2002000258A PE20021017A1 PE 20021017 A1 PE20021017 A1 PE 20021017A1 PE 2002000258 A PE2002000258 A PE 2002000258A PE 2002000258 A PE2002000258 A PE 2002000258A PE 20021017 A1 PE20021017 A1 PE 20021017A1
Authority
PE
Peru
Prior art keywords
weight
composition
reconstituable
cox
refers
Prior art date
Application number
PE2002000258A
Other languages
English (en)
Inventor
Tugrul Kararli
Sandeep Nema
Aziz Karim
Original Assignee
Pharmacia Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23075770&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20021017(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia Corp filed Critical Pharmacia Corp
Publication of PE20021017A1 publication Critical patent/PE20021017A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE COMPRENDE: a) AL MENOS UN AGENTE TERAPEUTICO SOLUBLE EN AGUA SELECCIONADO DE DROGAS INHIBIDORAS DE COX-2 SELECTIVAS SALES Y PRODROGAS EN UNA CANTIDAD TOTAL DE 30% A 90% EN PESO; b) DE 5% A 60% EN PESO DE UN AGENTE BUFFER PARENTERALMENTE ACEPTABLE Y c) DE 0% A 10% EN PESO DE OTROS INGREDIENTES O EXCIPIENTES. LA COMPOSICION COMPRENDE UN INHIBIDOR DE COX-2 SELECCIONADO DE CELECOXIB, DERACOXIB, VALDECOXIB, ROFECOXIB, ENTRE OTROS. LA COMPOSICION ES RECONSTITUIBLE EN UN SOLVENTE LIQUIDO PARENTERALMENTE ACEPTABLE PARA FORMAR UNA SOLUCION INYECTABLE.SE REFIERE TAMBIEN A UN PROCESO DE LIOFILIZACION PARA LA PREPARACION DE DICHA COMPOSICION
PE2002000258A 2001-04-03 2002-04-01 Composicion parenteral reconstituible PE20021017A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28105801P 2001-04-03 2001-04-03

Publications (1)

Publication Number Publication Date
PE20021017A1 true PE20021017A1 (es) 2002-11-24

Family

ID=23075770

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2002000258A PE20021017A1 (es) 2001-04-03 2002-04-01 Composicion parenteral reconstituible

Country Status (46)

Country Link
US (1) US7695736B2 (es)
EP (1) EP1372645B1 (es)
JP (1) JP4511792B2 (es)
KR (1) KR100980685B1 (es)
CN (3) CN107115302A (es)
AP (1) AP1776A (es)
AR (1) AR033688A1 (es)
AT (1) ATE310516T1 (es)
AU (1) AU2002256031B2 (es)
BG (1) BG66367B1 (es)
BR (1) BRPI0208652B8 (es)
CA (1) CA2442906C (es)
CZ (1) CZ299623B6 (es)
DE (1) DE60207535T2 (es)
DK (1) DK1372645T3 (es)
EA (1) EA006554B1 (es)
EC (1) ECSP034789A (es)
EG (1) EG24345A (es)
ES (1) ES2252448T3 (es)
GE (1) GEP20063775B (es)
GT (1) GT200200065A (es)
HK (2) HK1243338A1 (es)
HR (1) HRP20030793B1 (es)
HU (1) HU229264B1 (es)
IL (2) IL158209A0 (es)
IS (1) IS2408B (es)
JO (1) JO2337B1 (es)
MA (1) MA27008A1 (es)
ME (1) MEP56908A (es)
MX (1) MXPA03009013A (es)
MY (1) MY137736A (es)
NO (1) NO333381B1 (es)
NZ (1) NZ528547A (es)
OA (1) OA12498A (es)
PA (1) PA8542701A1 (es)
PE (1) PE20021017A1 (es)
PL (1) PL205658B1 (es)
RS (1) RS50430B (es)
SI (1) SI1372645T1 (es)
SK (1) SK287754B6 (es)
SV (1) SV2002000969A (es)
TN (2) TNSN02039A1 (es)
TW (1) TWI314867B (es)
UA (1) UA77173C2 (es)
WO (1) WO2002080912A1 (es)
ZA (1) ZA200307630B (es)

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CN104771370B (zh) * 2014-01-14 2020-07-24 南京圣和药业股份有限公司 帕瑞昔布钠冻干粉针剂及其制备方法
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CN105726496B (zh) * 2014-12-12 2019-05-28 湖南科伦药物研究有限公司 一种帕瑞昔布钠冻干粉剂、其制备方法及其粉剂产品
CN105125506A (zh) * 2015-08-18 2015-12-09 上海秀新臣邦医药科技有限公司 一种注射用帕瑞昔布钠及其制备方法
CN105168152B (zh) * 2015-08-27 2018-06-01 上海华源药业（宁夏）沙赛制药有限公司 一种帕瑞昔布钠冻干粉及其制备方法
US11243028B2 (en) * 2018-12-14 2022-02-08 Fortunata, LLC Systems and methods of cryo-curing
BR112021017127A2 (pt) 2019-03-01 2021-11-03 Eurofarma Laboratorios S A Composição farmacêutica liofilizada de antiinflamatório não esteroide, composição farmacêutica parenteral de anti-inflamatório não esteroide, composição farmacêutica parenteral reconstituível de anti-inflamatório não esteroide e produto farmacêutico estável
CN110960493B (zh) * 2019-12-30 2022-03-11 山东罗欣药业集团股份有限公司 一种帕瑞昔布钠冻干制剂及其制备方法
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