PE20000942A1 - Derivados de amida, carbamato y urea - Google Patents
Derivados de amida, carbamato y ureaInfo
- Publication number
- PE20000942A1 PE20000942A1 PE1999000765A PE00076599A PE20000942A1 PE 20000942 A1 PE20000942 A1 PE 20000942A1 PE 1999000765 A PE1999000765 A PE 1999000765A PE 00076599 A PE00076599 A PE 00076599A PE 20000942 A1 PE20000942 A1 PE 20000942A1
- Authority
- PE
- Peru
- Prior art keywords
- alkyl
- nraconra
- conra
- cyane
- nr3r4
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
- C07C233/13—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/18—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
- C07C255/60—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton at least one of the singly-bound nitrogen atoms being acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/14—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by halogen atoms or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/03—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C311/05—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atoms of the sulfonamide groups bound to hydrogen atoms or to acyclic carbon atoms to acyclic carbon atoms of hydrocarbon radicals substituted by nitrogen atoms, not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Abstract
SE REFIERE A DERIVADOS DE AMIDA DE FORMULA (I), DONDE B ES CONRa, NRaCO, NRaCONRa; Ra ES H, ALQUILO C1-C6; q ES 0-1; R1 ES NAFTILO, FENILO, FURILO, TIENILO, PIRIDILO OPCIONALMENTE SUSTITUIDO CON HALOGENO, NITRO, CIANO, (CH2)yX1R9; y ES 0-4; X1 ES O, S, NR10, CONR11, NR12CO, ENTRE OTROS; R9 ES H, ALQUILO C1-C10, ALQUENILO C3-C10, ENTRE OTROS; R10, R11, R12 SON H, ALQUILO C1-C10, O JUNTO CON N FORMAN UN GRUPO AZETIDINILO, PIRROLIDINILO, PIPERIDINILO, R14-(La)n-X2-(Lb)m-, ENTRE OTROS; X2 ES UN ENLACE, O, NH, S, SO, SO2, ENTRE OTROS; La Y Lb SON ALQUILENO C1-C4; UNO DE m Y n ES 0-1 Y EL OTRO ES 0; R14 ES FENILO, HETEROAROMATICO OPCIONALMENTE SUSTITUIDO CON HALOGENO, NITRO, CIANO, (CH2)zX3R15, ENTRE OTROS; z ES 0-4; X3 ES O, S, NR16, CO, CONR17, ENTRE OTROS; R2 ES H, ALQUILO C1-C6, CICLOALQUILO C3-C6, NR3R4, ENTRE OTROS; R3 Y R4 SON ALQUILO C1-C4 O JUNTO CON N FORMAN AZETIDINILO, PIRROLIDINILO, PIPERIDINILO, ENTRE OTROS; R5, R6, R7 Y R8 SON H, ALQUILO C1-C6, ARIL-ALQUILO C1-C6 O DOS DE R5, R6, R7 Y R8 FORMAN UN ANILLO CARBOCICLICO C3-C8 Y EL RESTO SON H; CUANDO R2 ES NR3R4, B NO ES NRaCONRa, CONRa. UN COMPUESTO PREFERIDO FORMULA A. EL COMPUESTO I ES UN POTENCIADOR DEL RECEPTOR DE GLUTAMATO POR LO QUE PUEDE SER UTIL PARA EL TRATAMIENTO DE UN TRASTORNO COGNITIVO, NEURODEGENERATIVO, DEMENCIA RELACIONADA CON LA EDAD, MEJORAR LA MEMORIA
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9499798P | 1998-07-31 | 1998-07-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20000942A1 true PE20000942A1 (es) | 2000-09-28 |
Family
ID=22248431
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE1999000765A PE20000942A1 (es) | 1998-07-31 | 1999-07-27 | Derivados de amida, carbamato y urea |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0976744A1 (es) |
JP (1) | JP2002521442A (es) |
AU (1) | AU5134499A (es) |
CA (1) | CA2338916A1 (es) |
CO (1) | CO5080795A1 (es) |
PE (1) | PE20000942A1 (es) |
SV (1) | SV1999000114A (es) |
WO (1) | WO2000006156A1 (es) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9702194D0 (en) | 1997-02-04 | 1997-03-26 | Lilly Co Eli | Sulphonide derivatives |
CA2372490A1 (en) | 1999-04-30 | 2000-11-09 | Eli Lilly And Company | Monofluoroalkyl derivatives |
US6639107B1 (en) | 1999-12-08 | 2003-10-28 | Eli Lilly And Company | Cyclopentyl sulfonamide derivatives |
EP1296944A1 (en) | 2000-05-19 | 2003-04-02 | Eli Lilly And Company | Sulfonamide derivatives |
IT1318636B1 (it) * | 2000-07-21 | 2003-08-27 | Roberto Pellicciari | Derivati dell'acido 2- o 3- tenoico ad attivita' antagonista deirecettori del glutammato. |
EP1313719A2 (en) * | 2000-08-11 | 2003-05-28 | Eli Lilly And Company | Heterocyclic sulfonamide derivatives and their use for potentiating glutamate receptor function |
WO2002014294A2 (en) * | 2000-08-11 | 2002-02-21 | Eli Lilly And Company | Heterocyclic sulfonamide derivatives and their use for potentiating glutamate receptor function |
EP3431464A3 (en) | 2003-08-06 | 2019-07-31 | Senomyx Inc. | Novel flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof |
EP1669348A4 (en) | 2003-09-30 | 2009-03-11 | Eisai R&D Man Co Ltd | NEW ANTIPILIC AGENT CONTAINING A HETEROCYCLIC COMPOUND |
FR2860514A1 (fr) * | 2003-10-03 | 2005-04-08 | Sanofi Synthelabo | Derives d'arylalkylcarbamates, leur preparation et leur application en therapeutique |
US7625932B2 (en) | 2003-10-08 | 2009-12-01 | Eli Lilly And Company | Pyrrole and pyrazole derivatives as potentiators of glutamate receptors |
DE602004021011D1 (de) * | 2003-10-08 | 2009-06-18 | Lilly Co Eli | Pyrrol- und pyrazolderivate als potentiatoren von glutamatrezeptoren |
ES2383115T3 (es) * | 2004-01-09 | 2012-06-18 | Eli Lilly And Company | Compuestos de tiofeno y furano |
CN101014571A (zh) * | 2004-01-30 | 2007-08-08 | 默克公司 | 用作hiv整合酶抑制剂的n-苄基-3,4-二羟基吡啶-2-羧酰胺类和n-苄基-2,3-二羟基吡啶-4-羧酰胺类化合物 |
JP4734346B2 (ja) | 2005-02-04 | 2011-07-27 | セノミックス インコーポレイテッド | 連結ヘテロアリール部分を含む化合物、ならびに食用組成物のための新規なうまみフレーバー改変剤、味物質および味覚増強剤としての使用 |
AU2006227729B2 (en) * | 2005-03-16 | 2011-10-13 | Aventis Pharmaceuticals Inc. | Dipyrazoles as central nervous system agents |
EP1864980A4 (en) | 2005-03-30 | 2010-08-18 | Eisai R&D Man Co Ltd | A PYRIDINE DERIVATIVE ANTIPILIC AGENT |
AR055329A1 (es) * | 2005-06-15 | 2007-08-15 | Senomyx Inc | Amidas bis-aromaticas y sus usos como modificadores de sabor dulce, saborizantes, y realzadores de sabor |
EP1749523A1 (en) * | 2005-07-29 | 2007-02-07 | Neuropharma, S.A. | GSK-3 inhibitors |
TWI385169B (zh) | 2005-10-31 | 2013-02-11 | Eisai R&D Man Co Ltd | 經雜環取代之吡啶衍生物及含有彼之抗真菌劑 |
DK3235811T3 (en) | 2006-04-21 | 2018-11-12 | Senomyx Inc | PROCEDURE FOR THE PREPARATION OF OXALAMIDS |
WO2008035726A1 (fr) | 2006-09-21 | 2008-03-27 | Eisai R & D Management Co., Ltd. | Dérivé de pyridine substitué par un cycle hétéroaryle, et agent antifongique le comprenant |
TW200841879A (en) | 2007-04-27 | 2008-11-01 | Eisai R&D Man Co Ltd | Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same |
AU2008246798A1 (en) | 2007-04-27 | 2008-11-13 | Eisai R&D Management Co., Ltd. | Salt of heterocycle-substituted pyridine derivative or crystal thereof |
US8513287B2 (en) | 2007-12-27 | 2013-08-20 | Eisai R&D Management Co., Ltd. | Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same |
US8188119B2 (en) | 2008-10-24 | 2012-05-29 | Eisai R&D Management Co., Ltd | Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same |
CN102711461A (zh) | 2009-12-29 | 2012-10-03 | Mapi医药公司 | 用于制备他喷他多及相关化合物的中间体化合物和方法 |
BR112015031249A2 (pt) | 2013-06-13 | 2017-07-25 | Veroscience Llc | método de tratamento, método para tratar um distúrbio metabólico ou um elemento chave do mesmo, método para normalizar um ritmo diário de liberação de dopamina no sumn, método para estimular a liberação de dopamina de neurônios dopaminérgicos no sumn de um indivíduo e composição farmacêutica |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3043868A (en) * | 1959-12-09 | 1962-07-10 | Searle & Co | N-xenylalkanoylaminoalkanoic acids and esters thereof |
DE1251755B (de) * | 1960-10-17 | 1967-10-12 | Smith Kline &. French Laboratories, Philadelphia, Pa (V St A) | Verfahren zur Herstellung von 2 Phenyl-cyclopropyl carbaminsaurederivaten |
DE1238455B (de) * | 1960-12-13 | 1967-04-13 | Troponwerke Dinklage & Co | Verfahren zur Herstellung von substituierten Phenyl-alkyl-harnstoffen |
BE764238A (fr) * | 1971-03-17 | 1971-09-13 | Lilly Industries Ltd | Derives de phenylalkylamine |
DE2329037A1 (de) * | 1973-06-07 | 1974-12-19 | Basf Ag | 3-biphenylyl-propionsaeuren und diese enthaltende arzneimittel |
AT341512B (de) * | 1975-01-09 | 1978-02-10 | Thomae Gmbh Dr K | Verfahren zur herstellung von neuen biphenylathern |
US4465509A (en) * | 1982-08-30 | 1984-08-14 | The Japan Carlit Co., Ltd. | Urea compounds and herbicidal compositions containing them |
GB2181728B (en) * | 1985-10-21 | 1990-01-24 | Indian Drugs & Pharma | 4-(3-thienyl)phenylalkanoic acids and derivatives and process for their preparation |
FR2689124A1 (fr) * | 1992-03-27 | 1993-10-01 | Adir | Nouvelles naphtylalkylamines, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
DK1156043T3 (da) * | 1992-07-24 | 2004-03-01 | Univ California | Lægemidler, der forøger synaptiske reaktioner formidlet af ampa-receptorer |
FR2696453B1 (fr) * | 1992-10-02 | 1994-12-23 | Adir | Nouveaux arylalkyl(thio)amides, leur procédé de préparation, et les compositions pharmaceutiques qui les contiennent. |
US5441984A (en) * | 1994-01-06 | 1995-08-15 | Eli Lilly And Company | Urea, thiourea and guanidine derivatives |
JPH10510512A (ja) * | 1994-10-04 | 1998-10-13 | 藤沢薬品工業株式会社 | 尿素誘導体とacat阻害剤としての用途 |
FR2737721B1 (fr) * | 1995-08-08 | 1997-09-05 | Roussel Uclaf | Nouveaux composes biphenyles, leur procede de preparation et les intermediaires de ce procede, leur application a titre de medicament et les compositions pharmaceutiques les contenant |
CA2250856A1 (en) * | 1996-04-19 | 1997-10-30 | The Regents Of The University Of California | Treatment of mood/affective disorders by glutamatergic upmodulators |
DK0810220T3 (da) * | 1996-05-28 | 2002-03-18 | Pfizer | Arylacrylamidderivater som 5-HT1-agonister eller -antagonister |
CA2207070A1 (en) * | 1996-06-14 | 1997-12-14 | James Erwin Fritz | Scavenger assisted combinatorial process for preparing libraries of amides, carbamates and sulfonamides |
CA2207164A1 (en) * | 1996-06-14 | 1997-12-14 | James Erwin Fritz | Scavenger assisted combinatorial process for preparing libraries of urea and thiourea compounds |
GB9702194D0 (en) * | 1997-02-04 | 1997-03-26 | Lilly Co Eli | Sulphonide derivatives |
CN1268942A (zh) * | 1997-06-27 | 2000-10-04 | 藤泽药品工业株式会社 | 磺酰胺化合物及其药物用途 |
-
1999
- 1999-07-27 PE PE1999000765A patent/PE20000942A1/es not_active Application Discontinuation
- 1999-07-28 EP EP99305981A patent/EP0976744A1/en not_active Withdrawn
- 1999-07-28 CA CA002338916A patent/CA2338916A1/en not_active Abandoned
- 1999-07-28 WO PCT/US1999/017126 patent/WO2000006156A1/en active Application Filing
- 1999-07-28 SV SV1999000114A patent/SV1999000114A/es unknown
- 1999-07-28 AU AU51344/99A patent/AU5134499A/en not_active Abandoned
- 1999-07-28 CO CO99047560A patent/CO5080795A1/es unknown
- 1999-07-28 JP JP2000562011A patent/JP2002521442A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
SV1999000114A (es) | 2000-07-04 |
CO5080795A1 (es) | 2001-09-25 |
AU5134499A (en) | 2000-02-21 |
JP2002521442A (ja) | 2002-07-16 |
WO2000006156A1 (en) | 2000-02-10 |
CA2338916A1 (en) | 2000-02-10 |
EP0976744A1 (en) | 2000-02-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PE20000942A1 (es) | Derivados de amida, carbamato y urea | |
PE20000944A1 (es) | Derivados de sulfonamida | |
CO4940442A1 (es) | Derivados de 4-bromo o 4-yodo fenilamino acido benzhidroxamico | |
GB1063894A (en) | Quinazolinedione derivatives | |
PE106499A1 (es) | Antagonistas del receptor ccr-3 | |
MY102027A (en) | Leukotriene antagonists | |
YU21590A (sh) | Derivati benzokondenziranih, n vsebujočih heterociklov in postopek za njihovo pripravo | |
PE20010671A1 (es) | Indolinonas sustituidas en posicion 6 como inhibidores de tirosina-quinasas | |
DK0417584T3 (da) | N-Substituerede 4-pyrimidinaminer og -pyrimidindiaminer, fremgangsmåde til deres fremstilling og deres anvendelser som læge | |
ES8601920A1 (es) | Procedimiento para la produccion n-fenilsulfonil-n'-pirimidinil-y -triacinil-ureas | |
CO5021130A1 (es) | Compuesto de amidina contienen | |
DK0706393T3 (da) | Immun-undertrykkende og antiallergiske forbindelser, f.eks. N-(3-oxohexanoyl)homoserin-lacton | |
CO5590960A2 (es) | Derivados de azaindolilalquilamina como ligandos de 5- hidroxitriptamina-6 | |
DE3378211D1 (de) | N-phenylsulfonyl-n'-pyrimidinyl- and -triazinyl urea | |
KR890008128A (ko) | 피페리딜아미노트리아진 유도체 및 안정화제로서의 그의 용도 | |
PE20040772A1 (es) | Composicion y actividad antiviral de derivados de piperazina azaindoloxoaceticos | |
DE69623799D1 (de) | Kondensierte tropanderivate als neurotransmitter-reuptake-inhibitoren | |
DK625584D0 (da) | 1,3,4,5-tetrahydrobenz(c,d)indoler, deres fremstilling og anvendelse | |
AR015964A1 (es) | Compuestos de isoquinolina, su uso, procedimiento para tratar una afeccion, procedimiento de preparacion del compuesto, composicion farmaceutica que locontiene y compuesto util en dicho procedimiento | |
AR015514A1 (es) | Compuesto de amida, proceso para su preparacion y composicion farmaceutica que lo contiene | |
ATE28873T1 (de) | Anellierte n-phenylsulfonyl-n'-pyrimidinyl- und - triazinylharnstoffe. | |
NO923964L (no) | Antimikrobielle kinolonyllaktaner | |
PE20000943A1 (es) | Derivados de sulfonamida | |
SE7514374L (sv) | N-(1-substituerade-3-pyrrolidinyl)-1-naftalens och 4-kinonlinkarboxiamider | |
ES433462A1 (es) | Un procedimiento de produccion de un derivado de pirazina. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Refusal |