BR112015031249A2 - método de tratamento, método para tratar um distúrbio metabólico ou um elemento chave do mesmo, método para normalizar um ritmo diário de liberação de dopamina no sumn, método para estimular a liberação de dopamina de neurônios dopaminérgicos no sumn de um indivíduo e composição farmacêutica - Google Patents
método de tratamento, método para tratar um distúrbio metabólico ou um elemento chave do mesmo, método para normalizar um ritmo diário de liberação de dopamina no sumn, método para estimular a liberação de dopamina de neurônios dopaminérgicos no sumn de um indivíduo e composição farmacêuticaInfo
- Publication number
- BR112015031249A2 BR112015031249A2 BR112015031249A BR112015031249A BR112015031249A2 BR 112015031249 A2 BR112015031249 A2 BR 112015031249A2 BR 112015031249 A BR112015031249 A BR 112015031249A BR 112015031249 A BR112015031249 A BR 112015031249A BR 112015031249 A2 BR112015031249 A2 BR 112015031249A2
- Authority
- BR
- Brazil
- Prior art keywords
- sumn
- dopamine release
- normalizing
- treating
- individual
- Prior art date
Links
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 title 4
- 229960003638 dopamine Drugs 0.000 title 2
- 210000005064 dopaminergic neuron Anatomy 0.000 title 1
- 208000030159 metabolic disease Diseases 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 230000004936 stimulating effect Effects 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361834864P | 2013-06-13 | 2013-06-13 | |
PCT/US2014/042397 WO2014201411A1 (en) | 2013-06-13 | 2014-06-13 | Compositions and methods for treating metabolic disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112015031249A2 true BR112015031249A2 (pt) | 2017-07-25 |
Family
ID=52022819
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112015031249A BR112015031249A2 (pt) | 2013-06-13 | 2014-06-13 | método de tratamento, método para tratar um distúrbio metabólico ou um elemento chave do mesmo, método para normalizar um ritmo diário de liberação de dopamina no sumn, método para estimular a liberação de dopamina de neurônios dopaminérgicos no sumn de um indivíduo e composição farmacêutica |
Country Status (9)
Country | Link |
---|---|
US (3) | US20150011554A1 (pt) |
EP (2) | EP3311842A1 (pt) |
JP (1) | JP2016521755A (pt) |
CN (1) | CN105579575A (pt) |
AU (1) | AU2014277952A1 (pt) |
BR (1) | BR112015031249A2 (pt) |
CA (1) | CA2915405A1 (pt) |
MX (1) | MX2015017253A (pt) |
WO (1) | WO2014201411A1 (pt) |
Families Citing this family (12)
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US9655865B2 (en) | 2002-07-29 | 2017-05-23 | Veroscience, Llc | Therapeutic treatment for metabolic syndrome, type 2 diabetes, obesity, or prediabetes |
US8821915B2 (en) | 2002-08-09 | 2014-09-02 | Veroscience, Llc | Therapeutic process for the treatment of the metabolic syndrome and associated metabolic disorders |
US20100035886A1 (en) | 2007-06-21 | 2010-02-11 | Veroscience, Llc | Parenteral formulations of dopamine agonists |
US8741918B2 (en) | 2007-06-21 | 2014-06-03 | Veroscience Llc | Parenteral formulations of dopamine agonists |
US20090137598A1 (en) | 2007-06-21 | 2009-05-28 | Veroscience, Llc | Method of treating metabolic disorders and depression with dopamine receptor agonists |
US9352025B2 (en) | 2009-06-05 | 2016-05-31 | Veroscience Llc | Combination of dopamine agonists plus first phase insulin secretagogues for the treatment of metabolic disorders |
US8431155B1 (en) | 2012-04-30 | 2013-04-30 | Veroscience Llc | Bromocriptine formulations |
DK3445362T3 (da) | 2016-04-20 | 2021-10-11 | Veroscience Llc | Sammensætning og fremgangsmåde til behandling af stofskiftesygdomme |
WO2019079623A1 (en) | 2017-10-18 | 2019-04-25 | Veroscience Llc | ENHANCED BROMOCRIPTINE FORMULATIONS |
US20200397751A1 (en) * | 2017-12-05 | 2020-12-24 | Peter Vanderklish | Modulation of AMPA/kainate Receptors for the Treatment of Hypoglycemia |
WO2020236696A1 (en) * | 2019-05-23 | 2020-11-26 | Dignity Health | Inhibitory interneuron treatment methods, uses and compositions for diabetes |
US11607455B2 (en) | 2019-09-23 | 2023-03-21 | Veroscience Llc | Method for inducing tumor regression |
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WO2011053869A2 (en) * | 2009-10-31 | 2011-05-05 | The Regents Of The University Of California | Manipulation of brain in a circuit-specific manner |
UY33551A (es) * | 2010-08-10 | 2012-03-30 | Takeda Pharmaceutical | Compuesto heterocíclico y su uso |
US8697898B2 (en) | 2011-11-23 | 2014-04-15 | Instytut Medycyny Doswiadczalnej i Klinicznej im. M. Mossakowskiego PAN | Medical application of lipid derivatives of dopamine and the methods of their production |
-
2014
- 2014-06-13 JP JP2016519696A patent/JP2016521755A/ja active Pending
- 2014-06-13 EP EP17206128.5A patent/EP3311842A1/en not_active Withdrawn
- 2014-06-13 AU AU2014277952A patent/AU2014277952A1/en not_active Abandoned
- 2014-06-13 BR BR112015031249A patent/BR112015031249A2/pt not_active Application Discontinuation
- 2014-06-13 CA CA2915405A patent/CA2915405A1/en not_active Abandoned
- 2014-06-13 WO PCT/US2014/042397 patent/WO2014201411A1/en active Application Filing
- 2014-06-13 MX MX2015017253A patent/MX2015017253A/es unknown
- 2014-06-13 EP EP14811295.6A patent/EP3008167A4/en not_active Withdrawn
- 2014-06-13 US US14/304,659 patent/US20150011554A1/en not_active Abandoned
- 2014-06-13 CN CN201480044899.5A patent/CN105579575A/zh active Pending
-
2018
- 2018-11-16 US US16/193,193 patent/US20190160059A1/en not_active Abandoned
-
2022
- 2022-01-04 US US17/568,560 patent/US20220142960A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP3008167A4 (en) | 2017-06-07 |
EP3008167A1 (en) | 2016-04-20 |
AU2014277952A1 (en) | 2016-01-28 |
EP3311842A1 (en) | 2018-04-25 |
US20150011554A1 (en) | 2015-01-08 |
CA2915405A1 (en) | 2014-12-18 |
JP2016521755A (ja) | 2016-07-25 |
WO2014201411A1 (en) | 2014-12-18 |
US20190160059A1 (en) | 2019-05-30 |
US20220142960A1 (en) | 2022-05-12 |
MX2015017253A (es) | 2016-04-19 |
CN105579575A (zh) | 2016-05-11 |
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