IT1318636B1 - Derivati dell'acido 2- o 3- tenoico ad attivita' antagonista deirecettori del glutammato. - Google Patents

Derivati dell'acido 2- o 3- tenoico ad attivita' antagonista deirecettori del glutammato.

Info

Publication number
IT1318636B1
IT1318636B1 IT2000MI001667A ITMI20001667A IT1318636B1 IT 1318636 B1 IT1318636 B1 IT 1318636B1 IT 2000MI001667 A IT2000MI001667 A IT 2000MI001667A IT MI20001667 A ITMI20001667 A IT MI20001667A IT 1318636 B1 IT1318636 B1 IT 1318636B1
Authority
IT
Italy
Prior art keywords
acid derivatives
antagonist activity
glutamate receptors
tenoic acid
tenoic
Prior art date
Application number
IT2000MI001667A
Other languages
English (en)
Inventor
Roberto Pellicciari
Flavio Moroni
Cristian Noe
Original Assignee
Roberto Pellicciari
Flavio Moroni
Noe Christian
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roberto Pellicciari, Flavio Moroni, Noe Christian filed Critical Roberto Pellicciari
Priority to IT2000MI001667A priority Critical patent/IT1318636B1/it
Publication of ITMI20001667A0 publication Critical patent/ITMI20001667A0/it
Priority to PCT/IB2001/001295 priority patent/WO2002008220A1/en
Priority to AU2001275767A priority patent/AU2001275767A1/en
Publication of ITMI20001667A1 publication Critical patent/ITMI20001667A1/it
Application granted granted Critical
Publication of IT1318636B1 publication Critical patent/IT1318636B1/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT2000MI001667A 2000-07-21 2000-07-21 Derivati dell'acido 2- o 3- tenoico ad attivita' antagonista deirecettori del glutammato. IT1318636B1 (it)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IT2000MI001667A IT1318636B1 (it) 2000-07-21 2000-07-21 Derivati dell'acido 2- o 3- tenoico ad attivita' antagonista deirecettori del glutammato.
PCT/IB2001/001295 WO2002008220A1 (en) 2000-07-21 2001-07-20 2-thenoic acid (thiophene) derivatives having glutamate receptor antagonistic activity
AU2001275767A AU2001275767A1 (en) 2000-07-21 2001-07-20 2-thenoic acid (thiophene) derivatives having glutamate receptor antagonistic activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2000MI001667A IT1318636B1 (it) 2000-07-21 2000-07-21 Derivati dell'acido 2- o 3- tenoico ad attivita' antagonista deirecettori del glutammato.

Publications (3)

Publication Number Publication Date
ITMI20001667A0 ITMI20001667A0 (it) 2000-07-21
ITMI20001667A1 ITMI20001667A1 (it) 2002-01-21
IT1318636B1 true IT1318636B1 (it) 2003-08-27

Family

ID=11445531

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2000MI001667A IT1318636B1 (it) 2000-07-21 2000-07-21 Derivati dell'acido 2- o 3- tenoico ad attivita' antagonista deirecettori del glutammato.

Country Status (3)

Country Link
AU (1) AU2001275767A1 (it)
IT (1) IT1318636B1 (it)
WO (1) WO2002008220A1 (it)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK124393D0 (da) * 1993-11-03 1993-11-03 Lundbeck & Co As H Compounds
US5962521A (en) * 1997-04-04 1999-10-05 Guilford Pharmaceuticals Inc. Hydroxamic acid derivatives
UA54403C2 (uk) * 1996-10-01 2003-03-17 Н'Юросерч А/С Похідні індол-2,3-діон-3-оксиму, фармацевтична композиція, спосіб лікування розладу чи захворювання ссавців, у тому числі людини та спосіб одержання похідних індол-2,3-діон-3-оксиму
GB9626151D0 (en) * 1996-12-17 1997-02-05 Lilly Industries Ltd Pharmaceutical compounds
PE20000942A1 (es) * 1998-07-31 2000-09-28 Lilly Co Eli Derivados de amida, carbamato y urea
AU5233699A (en) * 1998-07-31 2000-02-21 Eli Lilly And Company Sulfonamide derivatives
TW593241B (en) * 1999-04-20 2004-06-21 Hoffmann La Roche Carbamic acid derivatives

Also Published As

Publication number Publication date
ITMI20001667A0 (it) 2000-07-21
ITMI20001667A1 (it) 2002-01-21
AU2001275767A1 (en) 2002-02-05
WO2002008220A1 (en) 2002-01-31

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