PE1398A1 - Compuestos de bencilaminopiperidina sustituidos - Google Patents

Compuestos de bencilaminopiperidina sustituidos

Info

Publication number
PE1398A1
PE1398A1 PE1996000625A PE00062596A PE1398A1 PE 1398 A1 PE1398 A1 PE 1398A1 PE 1996000625 A PE1996000625 A PE 1996000625A PE 00062596 A PE00062596 A PE 00062596A PE 1398 A1 PE1398 A1 PE 1398A1
Authority
PE
Peru
Prior art keywords
compounds
halogen
benzlaminopiperidine
substituted
complete
Prior art date
Application number
PE1996000625A
Other languages
English (en)
Inventor
Kunio Satake
Yuji Shishido
Hiroaki Wakabayashi
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of PE1398A1 publication Critical patent/PE1398A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE REFIERE A COMPUESTOS DE FORMULA (I), EN DONDE: R ES HALOALQUILO C1-C8 O C(CF3)(R3)(R2), EN DONDE: R2 Y R3 SON HALOGENO, ENTRE OTROS, O R2 Y R3 COMPLETAN UN RADICAL ALQUIDENO C2-C6 OPCIONALMENTE SUSTITUIDO HASTA CON SIETE ATOMOS DE HALOGENO, (ESPECIFICAMENTE R ES CF3, DIFLUOROETILO, TRIFLUOROETILO O PENTAFLUOROETILO, ENTRE OTROS); R1 ES H, HALOGENO O ALCOXI C1-C6, O R Y R1 COMPLETAN UN CICLOALQUILO C4-C6 CONDENSADO; "X" ES METOXI, FENOXI O HALO, ENTRE OTROS; Ar ES FENILO. SON ANTAGONISTAS DE LA SUSTANCIA P, UTILES EN LA PREVENCION O TRATAMIENTO DE ENFERMEDADES DEL SNC, GASTROINTESTINALES O AFECCIONES CAUSADAS POR HELICOBACTER PYLORI, ENTRE OTROS
PE1996000625A 1995-08-24 1996-08-21 Compuestos de bencilaminopiperidina sustituidos PE1398A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IB9500683 1995-08-24

Publications (1)

Publication Number Publication Date
PE1398A1 true PE1398A1 (es) 1998-02-27

Family

ID=11004362

Family Applications (2)

Application Number Title Priority Date Filing Date
PE2001000276A PE20010700A1 (es) 1995-08-24 1996-08-21 Compuestos de bencilaminopiperidina sustituidos
PE1996000625A PE1398A1 (es) 1995-08-24 1996-08-21 Compuestos de bencilaminopiperidina sustituidos

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PE2001000276A PE20010700A1 (es) 1995-08-24 1996-08-21 Compuestos de bencilaminopiperidina sustituidos

Country Status (42)

Country Link
US (1) US6506775B1 (es)
EP (2) EP0861235B1 (es)
JP (1) JP3084069B2 (es)
KR (1) KR100288673B1 (es)
CN (1) CN1153764C (es)
AP (1) AP643A (es)
AR (1) AR006305A1 (es)
AT (2) ATE208377T1 (es)
AU (1) AU702698B2 (es)
BG (1) BG64126B1 (es)
BR (1) BR9609989A (es)
CA (1) CA2227814C (es)
CO (1) CO4480738A1 (es)
CZ (1) CZ297543B6 (es)
DE (2) DE69631390T2 (es)
DK (2) DK1114817T3 (es)
DZ (1) DZ2086A1 (es)
ES (2) ES2211684T3 (es)
HK (1) HK1014935A1 (es)
HR (1) HRP960386B1 (es)
HU (1) HU225480B1 (es)
IL (1) IL119078A (es)
IS (1) IS1947B (es)
MA (1) MA23961A1 (es)
MX (1) MX9801467A (es)
MY (1) MY114800A (es)
NO (1) NO310720B1 (es)
NZ (1) NZ308207A (es)
OA (1) OA10666A (es)
PE (2) PE20010700A1 (es)
PL (1) PL186773B1 (es)
PT (2) PT861235E (es)
RO (1) RO119299B1 (es)
RU (1) RU2152930C2 (es)
SI (2) SI0861235T1 (es)
SK (1) SK282925B6 (es)
TN (1) TNSN96107A1 (es)
TR (1) TR199800300T1 (es)
TW (1) TW340842B (es)
UA (1) UA48981C2 (es)
WO (1) WO1997008144A1 (es)
YU (1) YU49122B (es)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX9706196A (es) * 1996-08-14 1998-02-28 Pfizer Compuestos triciclicos de piperidinilamino como antagonistas de la sustancia p.
TW426667B (en) * 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists
US6777428B1 (en) 1999-02-10 2004-08-17 Eli Lilly And Company 5-HT1f agonist
EP1175417B1 (en) * 1999-05-06 2004-01-07 Pfizer Products Inc. Substituted benzolactam compounds
RS49964B (sr) 1999-05-17 2008-09-29 Pfizer Products Inc., Postupak za dobijanje 2-fenil-3-aminopiridina,njegovih supstituisanih fenil derivata, i njegovih soli
WO2000071538A2 (en) * 1999-05-21 2000-11-30 Pfizer Products Inc. 1-trifluoromethyl-4-hydroxy-7-piperidinyl-aminomethylchroman derivatives
JP2001172178A (ja) * 1999-10-25 2001-06-26 Pfizer Prod Inc 偏頭痛治療用のnk−1レセプターアンタゴニスト及びエレトリプタン
US20020049211A1 (en) * 2000-09-06 2002-04-25 Sobolov-Jaynes Susan Beth Combination treatment for depression and anxiety
EP1192952A3 (en) * 2000-09-28 2003-03-26 Pfizer Products Inc. Combination, for treating depression and anxiety, containing an NK-3 receptor antagonist and a CNS penetrant NK-1 receptor antagonist
US6911544B2 (en) 2002-10-23 2005-06-28 Pfizer Inc. Process for the preparation of (S,S)-cis-2-phenyl-3-aminopiperidine
WO2004094380A1 (en) 2003-04-18 2004-11-04 Eli Lilly And Company (piperidinyloxy)phenyl, (piperidinyloxy)pyridinyl, (piperidinylsulfanyl)phenyl and (piperidinylsulfanyl)pyridinyl compounds as 5-ht1f agonists
CA2566920A1 (en) * 2004-05-21 2005-12-01 Pfizer Products Inc. Metabolites of (+)-(2s, 3s)-3-(2-methoxy-5-trifluoromethoxybenzylamino)-2-phenyl-piperidine
US7541357B2 (en) 2004-07-15 2009-06-02 Amr Technology, Inc. Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
ATE550019T1 (de) 2005-05-17 2012-04-15 Merck Sharp & Dohme Cis-4-ä(4-chlorophenyl)sulfonylü-4-(2,5- difluorophenyl)cyclohexanepropansäure zur behandlug von krebs
GEP20125566B (en) 2005-07-15 2012-07-10 Amr Technology Inc Aryl-and heteroaryl-substituded tetrahydro-benzazepines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
AU2006297443B2 (en) 2005-09-29 2010-08-12 Merck Sharp & Dohme Corp. Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
GB0603041D0 (en) 2006-02-15 2006-03-29 Angeletti P Ist Richerche Bio Therapeutic compounds
CA2664113C (en) 2006-09-22 2013-05-28 Merck & Co., Inc. Use of platencin and platensimycin as fatty acid synthesis inhibitors to treat obesity, diabetes and cancer
US20110218176A1 (en) 2006-11-01 2011-09-08 Barbara Brooke Jennings-Spring Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
JP4611444B2 (ja) 2007-01-10 2011-01-12 イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー ポリ(adp−リボース)ポリメラーゼ(parp)阻害剤としてのアミド置換インダゾール
CA2682727C (en) 2007-04-02 2016-03-22 Banyu Pharmaceutical Co., Ltd. Indoledione derivative
EP3103791B1 (en) 2007-06-27 2018-01-31 Merck Sharp & Dohme Corp. 4-carboxybenzylamino derivatives as histone deacetylase inhibitors
US8598184B2 (en) 2008-03-03 2013-12-03 Tiger Pharmatech Protein kinase inhibitors
US7951822B2 (en) 2008-03-31 2011-05-31 Kowa Company, Ltd. 1,3-dihydroisobenzofuran derivatives
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
WO2010114780A1 (en) 2009-04-01 2010-10-07 Merck Sharp & Dohme Corp. Inhibitors of akt activity
PE20120373A1 (es) 2009-05-12 2012-05-17 Albany Molecular Res Inc 7-([1,2,4]triazolo[1,5-a]piridin-6-il)-4-(3,4-diclorofenil)-1,2,3,4-tetrahidroisoquinolina
WO2010132487A1 (en) 2009-05-12 2010-11-18 Bristol-Myers Squibb Company CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF
CN102458123A (zh) 2009-05-12 2012-05-16 阿尔巴尼分子研究公司 芳基、杂芳基和杂环取代的四氢异喹啉及其用途
JP5099731B1 (ja) 2009-10-14 2012-12-19 メルク・シャープ・アンド・ドーム・コーポレーション p53活性を増大する置換ピペリジン及びその使用
EP2584903B1 (en) 2010-06-24 2018-10-24 Merck Sharp & Dohme Corp. Novel heterocyclic compounds as erk inhibitors
US8518907B2 (en) 2010-08-02 2013-08-27 Merck Sharp & Dohme Corp. RNA interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (CTNNB1) gene expression using short interfering nucleic acid (siNA)
DK2606134T3 (da) 2010-08-17 2019-07-22 Sirna Therapeutics Inc RNA-Interferens-formidlet inhibering af hepatitis-B-virus (HBV)-genekspression ved hjælp af kort interfererende nukleinsyre (siNA)
EP2608669B1 (en) 2010-08-23 2016-06-22 Merck Sharp & Dohme Corp. NOVEL PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS
WO2012030685A2 (en) 2010-09-01 2012-03-08 Schering Corporation Indazole derivatives useful as erk inhibitors
US9242981B2 (en) 2010-09-16 2016-01-26 Merck Sharp & Dohme Corp. Fused pyrazole derivatives as novel ERK inhibitors
DK2632472T3 (en) 2010-10-29 2018-03-19 Sirna Therapeutics Inc RNA INTERFERENCE-MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERRING NUCLEIC ACIDS (SINA)
EP2654748B1 (en) 2010-12-21 2016-07-27 Merck Sharp & Dohme Corp. Indazole derivatives useful as erk inhibitors
US20140045847A1 (en) 2011-04-21 2014-02-13 Piramal Enterprises Limited Crystalline form of a salt of a morpholino sulfonyl indole derivative and a process for its preparation
WO2013063214A1 (en) 2011-10-27 2013-05-02 Merck Sharp & Dohme Corp. Novel compounds that are erk inhibitors
EP3358013B1 (en) 2012-05-02 2020-06-24 Sirna Therapeutics, Inc. Short interfering nucleic acid (sina) compositions
RU2660429C2 (ru) 2012-09-28 2018-07-06 Мерк Шарп И Доум Корп. Новые соединения, которые являются ингибиторами erk
JP6440625B2 (ja) 2012-11-14 2018-12-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 精神***病を処置するための方法および組成物
AU2013352568B2 (en) 2012-11-28 2019-09-19 Merck Sharp & Dohme Llc Compositions and methods for treating cancer
ES2707305T3 (es) 2012-12-20 2019-04-03 Merck Sharp & Dohme Imidazopiridinas sustituidas como inhibidores de HDM2
WO2014120748A1 (en) 2013-01-30 2014-08-07 Merck Sharp & Dohme Corp. 2,6,7,8 substituted purines as hdm2 inhibitors
WO2015034925A1 (en) 2013-09-03 2015-03-12 Moderna Therapeutics, Inc. Circular polynucleotides
EP3706742B1 (en) 2017-11-08 2023-03-15 Merck Sharp & Dohme LLC Prmt5 inhibitors
EP3833667B1 (en) 2018-08-07 2024-03-13 Merck Sharp & Dohme LLC Prmt5 inhibitors
WO2020033282A1 (en) 2018-08-07 2020-02-13 Merck Sharp & Dohme Corp. Prmt5 inhibitors

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5232929A (en) * 1990-11-28 1993-08-03 Pfizer Inc. 3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
US5364943A (en) * 1991-11-27 1994-11-15 Pfizer Inc. Preparation of substituted piperidines
CZ293955B6 (cs) * 1991-03-26 2004-08-18 Pfizeráinc Postup přípravy substituovaných piperidinů
DE69213451T2 (de) * 1991-06-20 1997-01-09 Pfizer Fluoralkoxybenzylaminoderivate stickstoffhaltiger heterocyclen
US5340826A (en) * 1993-02-04 1994-08-23 Pfizer Inc. Pharmaceutical agents for treatment of urinary incontinence
US5393762A (en) * 1993-06-04 1995-02-28 Pfizer Inc. Pharmaceutical agents for treatment of emesis
EP0653208A3 (en) * 1993-11-17 1995-10-11 Pfizer Substance P antagonists for the treatment or prevention of sunburn.
EP0655246A1 (en) * 1993-11-30 1995-05-31 Pfizer Inc. Substance P antagonists for the treatment of disorders caused by helicobacter pylori or other spiral urease-positive gram-negative bacteria
DE69623580T2 (de) * 1995-12-21 2003-01-09 Pfizer 3-((5-Substituierte Benzyl)Amino)-2-Phenylpiperidine als Substance-P-Antagonisten
US5990125A (en) 1996-01-19 1999-11-23 Pfizer Inc. NK-1 receptor antagonists for the treatment of cancer

Also Published As

Publication number Publication date
PT1114817E (pt) 2004-05-31
DE69616817T2 (de) 2002-04-04
MA23961A1 (fr) 1997-04-01
IL119078A0 (en) 1996-11-14
CA2227814C (en) 2002-12-31
CN1153764C (zh) 2004-06-16
SK20798A3 (en) 1999-03-12
DK0861235T3 (da) 2001-12-27
NO310720B1 (no) 2001-08-20
AP643A (en) 1998-04-24
PT861235E (pt) 2002-03-28
DE69631390T2 (de) 2004-11-25
EP0861235A1 (en) 1998-09-02
BG64126B1 (bg) 2004-01-30
HRP960386A2 (en) 1998-04-30
HRP960386B1 (en) 2002-04-30
AP9600850A0 (en) 1996-10-31
KR19990044077A (ko) 1999-06-25
IS4644A (is) 1997-12-30
ES2211684T3 (es) 2004-07-16
TW340842B (en) 1998-09-21
IS1947B (is) 2004-10-13
BG102288A (en) 1998-09-30
RO119299B1 (ro) 2004-07-30
YU47896A (sh) 1998-12-23
NO980751L (no) 1998-02-23
KR100288673B1 (ko) 2001-05-02
NZ308207A (en) 1998-07-28
TR199800300T1 (xx) 1998-06-22
YU49122B (sh) 2004-03-12
EP0861235B1 (en) 2001-11-07
CZ52198A3 (cs) 1999-01-13
CO4480738A1 (es) 1997-07-09
ATE208377T1 (de) 2001-11-15
CA2227814A1 (en) 1997-03-06
JPH10510554A (ja) 1998-10-13
US6506775B1 (en) 2003-01-14
SI0861235T1 (en) 2002-04-30
DZ2086A1 (fr) 2002-07-22
DE69616817D1 (de) 2001-12-13
CN1193961A (zh) 1998-09-23
SI1114817T1 (en) 2004-06-30
EP1114817B1 (en) 2004-01-21
PL186773B1 (pl) 2004-02-27
PL325332A1 (en) 1998-07-20
ES2163017T3 (es) 2002-01-16
EP1114817A1 (en) 2001-07-11
NO980751D0 (no) 1998-02-23
PE20010700A1 (es) 2001-07-09
SK282925B6 (sk) 2003-01-09
HUP9901159A3 (en) 2000-05-29
OA10666A (en) 2002-11-25
DE69631390D1 (de) 2004-02-26
HU225480B1 (en) 2006-12-28
AU5776996A (en) 1997-03-19
HK1014935A1 (en) 1999-10-08
ATE258166T1 (de) 2004-02-15
AU702698B2 (en) 1999-03-04
BR9609989A (pt) 1999-07-06
TNSN96107A1 (fr) 2005-03-15
WO1997008144A1 (en) 1997-03-06
MY114800A (en) 2003-01-31
RU2152930C2 (ru) 2000-07-20
JP3084069B2 (ja) 2000-09-04
IL119078A (en) 2003-11-23
UA48981C2 (uk) 2002-09-16
AR006305A1 (es) 1999-08-25
MX9801467A (es) 1998-05-31
HUP9901159A2 (hu) 1999-07-28
DK1114817T3 (da) 2004-04-26
CZ297543B6 (cs) 2007-02-07

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