OA07966A - Procédé de production d'un 2-oxindole-1-carboxamide et produit obtenu. - Google Patents

Procédé de production d'un 2-oxindole-1-carboxamide et produit obtenu.

Info

Publication number: OA07966A
Authority: OA; OAPI
Prior art keywords: alkyl; optionally substituted; oxindole; bicyclo; compounds
Prior art date: 1984-03-19

Application number

OA58541A

Other languages

English (en)

Inventor

Kadin Saul Bernard

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-03-19

Filing date

1985-03-19

Publication date

1987-01-31

1985-03-19 Application filed by Pfizer filed Critical Pfizer

1987-01-31 Publication of OA07966A publication Critical patent/OA07966A/fr

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pain & Pain Management (AREA)
Public Health (AREA)
Rheumatology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)

OA58541A 1984-03-19 1985-03-19 Procédé de production d'un 2-oxindole-1-carboxamide et produit obtenu. OA07966A (fr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US59065984A	1984-03-19	1984-03-19
US06/684,634 US4556672A (en)	1984-03-19	1984-12-21	3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents

Publications (1)

Publication Number	Publication Date
OA07966A true OA07966A (fr)	1987-01-31

Family

ID=27080909

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
OA58541A OA07966A (fr)	1984-03-19	1985-03-19	Procédé de production d'un 2-oxindole-1-carboxamide et produit obtenu.

Country Status (36)

Country	Link
US (1)	US4556672A (fr)
EP (1)	EP0156603B1 (fr)
JP (1)	JPH04235165A (fr)
KR (1)	KR860001873B1 (fr)
AT (1)	ATE45731T1 (fr)
AU (1)	AU549927B2 (fr)
BG (1)	BG60347B2 (fr)
CA (2)	CA1251441A (fr)
CS (1)	CS249539B2 (fr)
CY (1)	CY1668A (fr)
DE (1)	DE3572481D1 (fr)
DK (1)	DK162090C (fr)
EG (1)	EG17795A (fr)
ES (1)	ES541372A0 (fr)
FI (2)	FI82042C (fr)
GR (1)	GR850668B (fr)
HK (1)	HK78392A (fr)
HU (1)	HU196178B (fr)
IE (1)	IE57743B1 (fr)
IL (3)	IL74631A (fr)
LV (1)	LV5618A3 (fr)
MA (1)	MA20380A1 (fr)
MY (1)	MY101987A (fr)
NL (1)	NL940025I2 (fr)
NO (1)	NO165799C (fr)
NZ (2)	NZ211486A (fr)
OA (1)	OA07966A (fr)
PH (2)	PH21323A (fr)
PL (1)	PL145951B1 (fr)
PT (1)	PT80117B (fr)
RO (1)	RO90952B (fr)
SI (1)	SI8510440A8 (fr)
SU (1)	SU1445556A3 (fr)
UA (1)	UA6343A1 (fr)
YU (1)	YU43870B (fr)
ZW (1)	ZW4785A1 (fr)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
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GR850310B (fr) *	1984-02-07	1985-06-05	Pfizer
US4686224A (en) *	1984-10-31	1987-08-11	Pfizer Inc.	Oxindole antiinflammatory agents
ATE67185T1 (de) *	1985-07-09	1991-09-15	Pfizer	Substituierte oxindol-3-carboxamine als entzuendungshemmendes und schmerzstillendes mittel.
US4678802A (en) *	1985-07-09	1987-07-07	Pfizer Inc.	1-acylcarbamoyloxindole-3-carboxamides as antiinflammatory agents
GB8623819D0 (en) *	1986-10-03	1986-11-05	Glaxo Group Ltd	Heterocyclic compounds
RO105052B1 (en)	1987-02-02	1994-12-01	Pfizer	Producing process for the crystalline sodium salt, anhydre, of 5-chlorine-3-(2-tenoil)-2-oxindol-1-carboxamide
US4761485A (en) *	1987-03-11	1988-08-02	Pfizer Inc.	Synthetic method for indol-2(3H)-ones
US4885370A (en) *	1987-03-11	1989-12-05	Pfizer Inc.	Synthetic method for indol-2(3H)-ones
GB8720693D0 (en) *	1987-09-03	1987-10-07	Glaxo Group Ltd	Chemical compounds
DE3803775A1 (de) *	1988-02-09	1989-08-17	Boehringer Mannheim Gmbh	Neue substituierte lactame, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
US4853409A (en) *	1988-04-13	1989-08-01	Pfizer Inc.	3-substituted-2-oxindole-1-carboxamides for suppressing T-cell function
US4861794A (en) *	1988-04-13	1989-08-29	Pfizer Inc.	3-substituted-2-oxindole-1-carboxamides as inhibitors of interleukin-1 biosynthesis
EP0365194B1 (fr) *	1988-10-18	1995-08-02	Pfizer Inc.	Prodrogues de 3-aryl-2-oxindole-1-carboxamide antiinflammatoires
HU208421B (en) *	1988-10-18	1993-10-28	Pfizer	Process for producing starting materials for producing 3-acyl-2-oxindol-carboxamides ofantiphlogistic activity
WO1990008145A1 (fr) *	1989-01-10	1990-07-26	Pfizer Inc.	1-heteroaryl-3-acyl-2-indoxyles anti-inflammatoires
US5300655A (en) *	1989-04-18	1994-04-05	Pfizer Inc.	2-carboxy-thiophene derivatives
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US5059693A (en) *	1989-10-06	1991-10-22	Pfizer Inc.	Process for making 3-aroyl-2-oxindole-1-carboxamides
IL95880A (en) *	1989-10-13	1995-12-31	Pfizer	Use of 3-Transformed History of 2-Oxindole for the Preparation of Pharmaceuticals for Inhibition of Interlaukio-1 Biosynthesis
WO1991009598A1 (fr) *	1990-01-05	1991-07-11	Pfizer Inc.	Derives de l'azaoxindole
US5006547A (en) *	1990-03-19	1991-04-09	Pfizer Inc.	Tenidap as an inhibitor of the release of elastase by neutrophils
US5008283A (en) *	1990-03-19	1991-04-16	Pfizer Inc.	Use of tenidap to inhibit activation of collagenase and to inhibit the activity of myeloperoxidase
US5064851A (en) *	1990-07-24	1991-11-12	Pfizer Inc.	3-(1-substituted-pyrazoyl)-2-oxindole derivatives, compositions and use
US5095031A (en) *	1990-08-20	1992-03-10	Abbott Laboratories	Indole derivatives which inhibit leukotriene biosynthesis
US5122534A (en) *	1991-02-08	1992-06-16	Pfizer Inc.	Use of tenidap to reduce total serum cholesterol, ldl cholesterol and triglycerides
DE4111306C2 (de) *	1991-04-08	1994-06-01	Mack Chem Pharm	Pharmazeutische Zubereitungen, die ein 2-Oxindol-l-carboxamid-derivat enthalten und zur Injektion bestimmt sind
DE4111305C2 (de) *	1991-04-08	1994-12-01	Mack Chem Pharm	Pharmazeutische Zubereitung zur rektalen Applikation, die ein 2-Oxindol-l-carboxamid-derivat enthält
US5210212A (en) *	1991-06-25	1993-05-11	Pfizer Inc	Process for 5-fluoro-6-chlorooxindole
US5166401A (en) *	1991-06-25	1992-11-24	Pfizer Inc	Intermediates for 5-fluoro-6-chlorooxindole
TW438798B (en) *	1992-10-07	2001-06-07	Pfizer	3-substituted 2-oxindole-1-carboxamide pharmaceutical compositions
US5288743A (en) *	1992-11-20	1994-02-22	Abbott Laboratories	Indole carboxylate derivatives which inhibit leukotriene biosynthesis
BR9405661A (pt) *	1993-01-22	1995-11-21	Pfizer	Sal de lisina de 6-cloro-5-flúor-3-(2-tenoil)-2-oxindole-1-carboxamida
US5298522A (en) *	1993-01-22	1994-03-29	Pfizer Inc.	6-chloro-5-fluoro-3-(2-thenoyl)-2-oxindole-1-carboxamide as an analgesic and anti-inflammatory agent while maintaining a normal urine protein/creatinine ratio
US5270331A (en) *	1993-01-26	1993-12-14	Pfizer, Inc.	Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides
DE69305999T2 (de) *	1993-02-09	1997-03-06	Pfizer Inc., New York, N.Y.	Oxindol 1-[n-(alkoxycarbonyl)]carboxamide und 1-[n-carboxamido]carboxamide als antiinflammatorische wirkstoffe
ES2076106B1 (es) *	1993-08-26	1996-06-16	Pfizer	Composiciones farmaceuticas a base de 2-oxindol-1-carboxamidas 3-sustituidas
US5449788A (en) *	1994-01-28	1995-09-12	Catalytica, Inc.	Process for preparing 2-oxindole-1-carboxamides
EP0679396A1 (fr) *	1994-03-02	1995-11-02	Pfizer Inc.	Utilisation de dérivés oxindol-2-carboxamides-1,3-substitués pour la fabrication d'un médicament destiné au traiter des dommages du myocardes causés par une ischémie et les dommages du myocardes induits par les cytokines
US6469181B1 (en)	1995-01-30	2002-10-22	Catalytica, Inc.	Process for preparing 2-oxindoles and N-hydroxy-2-oxindoles
US5545656A (en) *	1995-04-05	1996-08-13	Pfizer Inc.	2-Oxidole-1-carboxamide pharmaceutical agents for the treatment of alzheimer's disease
US5703073A (en) *	1995-04-19	1997-12-30	Nitromed, Inc.	Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs
US6043232A (en) *	1997-07-23	2000-03-28	Nitromed, Inc.	Nitroso esters of beta-oxo-amides and aryl propionic acid derivatives of non-steroidal antiinflammatory drugs
US6051588A (en) *	1995-04-19	2000-04-18	Nitromed Inc	Nitroso esters of β-oxo-amides and aryl propionic acid derivatives of non-steroidal antiinflammatory drugs
WO1997022605A1 (fr) *	1995-12-19	1997-06-26	Pfizer Inc.	Sels stables et a action prolongee de derives d'indole pour le traitement de maladies articulaires
HUP9600855A3 (en) *	1996-04-03	1998-04-28	Egyt Gyogyszervegyeszeti Gyar	Process for producing tenidap
EP0826685A1 (fr) *	1996-08-21	1998-03-04	Pfizer Inc.	Sels de carboxamides stables à effet prolongé destinés au traitement des maladies articulaires
AU763000B2 (en)	1998-10-30	2003-07-10	Nicox S.A.	Nitrosated and nitrosylated nonsteroidal antiinflammatory compounds, compositions and methods of use
CA2354873A1 (fr)	1998-12-17	2000-06-22	F. Hoffmann-La Roche Ag	4-alcenyl (et alcynyl) oxindoles utilises comme inhibiteurs de kinases dependantes des cyclines, en particulier la cdk2
JP2002532493A (ja)	1998-12-17	2002-10-02	エフ．ホフマン−ラロシュアーゲー	Ｊｎｋプロテインキナーゼ阻害剤としての４−アリールオキシインドール
TR200101756T2 (tr)	1998-12-17	2001-10-22	F.Hoffmann-La Roche Ag	Protein kinaz inhibitörleri olarak 4,5-pirazinoksindoller.
US6153634A (en)	1998-12-17	2000-11-28	Hoffmann-La Roche Inc.	4,5-azolo-oxindoles
IT1308633B1 (it)	1999-03-02	2002-01-09	Nicox Sa	Nitrossiderivati.
JP2003512396A (ja) *	1999-10-26	2003-04-02	ザ・ユニバーシティ・オブ・テキサス・サウスウエスタン・メディカル・センター	インドリン化合物を投与することを含む脱毛症の処置方法
US6313310B1 (en)	1999-12-15	2001-11-06	Hoffmann-La Roche Inc.	4-and 5-alkynyloxindoles and 4-and 5-alkenyloxindoles
IT1318673B1 (it) *	2000-08-08	2003-08-27	Nicox Sa	Farmaci per le disfunzioni sessuali.
IT1318674B1 (it) *	2000-08-08	2003-08-27	Nicox Sa	Faramaci per l'incontinenza.
US20030129186A1 (en)	2001-07-25	2003-07-10	Biomarin Pharmaceutical Inc.	Compositions and methods for modulating blood-brain barrier transport
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ES2942923T3 (es)	2009-05-06	2023-06-07	Laboratory Skin Care Inc	Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
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NL125443C (fr) *	1963-06-06
US3462450A (en) *	1966-06-29	1969-08-19	Merck & Co Inc	Chemical compounds
GB1158532A (en) *	1967-01-05	1969-07-16	Centre Nat Rech Scient	2-Oxoindoline-3-Carboxylic Acids and Esters thereof
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DE2306374A1 (de) *	1973-02-09	1974-08-15	Bayer Ag	Neue 3-substituierte 2-oxo-4-hydroxy1,2,3,4-tetrahydrochinazolin-4-carbonsaeureamide
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DE2314242A1 (de) *	1973-03-22	1974-09-26	Bayer Ag	Neue 3-substituierte 2-oxo-4-hydroxy1,2,3,4-tetrahydrochinazolin-4-carbonsaeurehydrazide
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1984
- 1984-12-21 US US06/684,634 patent/US4556672A/en not_active Expired - Lifetime
1985
- 1985-03-15 DE DE8585301808T patent/DE3572481D1/de not_active Expired
- 1985-03-15 AT AT85301808T patent/ATE45731T1/de not_active IP Right Cessation
- 1985-03-15 CA CA000476605A patent/CA1251441A/fr not_active Expired
- 1985-03-15 PT PT80117A patent/PT80117B/pt unknown
- 1985-03-15 GR GR850668A patent/GR850668B/el unknown
- 1985-03-15 IE IE684/85A patent/IE57743B1/en not_active IP Right Cessation
- 1985-03-15 EP EP85301808A patent/EP0156603B1/fr not_active Expired
- 1985-03-17 EG EG174/85A patent/EG17795A/xx active
- 1985-03-18 UA UA3869754A patent/UA6343A1/uk unknown
- 1985-03-18 IL IL74631A patent/IL74631A/xx not_active IP Right Cessation
- 1985-03-18 SU SU853869754A patent/SU1445556A3/ru active
- 1985-03-18 FI FI851069A patent/FI82042C/fi not_active IP Right Cessation
- 1985-03-18 PH PH32001A patent/PH21323A/en unknown
- 1985-03-18 IL IL85130A patent/IL85130A/xx not_active IP Right Cessation
- 1985-03-18 KR KR1019850001746A patent/KR860001873B1/ko not_active IP Right Cessation
- 1985-03-18 MA MA20604A patent/MA20380A1/fr unknown
- 1985-03-18 NZ NZ211486A patent/NZ211486A/xx unknown
- 1985-03-18 AU AU40059/85A patent/AU549927B2/en not_active Expired
- 1985-03-18 BG BG69278A patent/BG60347B2/bg unknown
- 1985-03-18 PL PL1985252434A patent/PL145951B1/pl unknown
- 1985-03-18 DK DK121385A patent/DK162090C/da not_active IP Right Cessation
- 1985-03-18 ZW ZW47/85A patent/ZW4785A1/xx unknown
- 1985-03-18 NO NO851054A patent/NO165799C/no not_active IP Right Cessation
- 1985-03-18 NZ NZ224134A patent/NZ224134A/xx unknown
- 1985-03-18 HU HU85992A patent/HU196178B/hu unknown
- 1985-03-18 ES ES541372A patent/ES541372A0/es active Granted
- 1985-03-19 RO RO118055A patent/RO90952B/ro unknown
- 1985-03-19 SI SI8510440A patent/SI8510440A8/sl unknown
- 1985-03-19 OA OA58541A patent/OA07966A/fr unknown
- 1985-03-19 CS CS851920A patent/CS249539B2/cs unknown
- 1985-03-19 YU YU440/85A patent/YU43870B/xx unknown
1986
- 1986-02-21 PH PH33439A patent/PH21470A/en unknown
1987
- 1987-08-17 MY MYPI87001358A patent/MY101987A/en unknown
1988
- 1988-01-19 IL IL85130A patent/IL85130A0/xx unknown
- 1988-07-07 CA CA000571475A patent/CA1288422C/fr not_active Expired - Fee Related
1989
- 1989-09-26 FI FI894540A patent/FI82449C/fi not_active IP Right Cessation
1991
- 1991-06-04 JP JP3132826A patent/JPH04235165A/ja active Granted
1992
- 1992-10-15 HK HK783/92A patent/HK78392A/xx not_active IP Right Cessation
1993
- 1993-05-14 CY CY1668A patent/CY1668A/xx unknown
- 1993-11-11 LV LV931200A patent/LV5618A3/xx unknown
1994
- 1994-12-15 NL NL940025C patent/NL940025I2/nl unknown

Also Published As

Publication number	Publication date
NL940025I2 (nl)	2000-01-03
FI851069A0 (fi)	1985-03-18
HK78392A (en)	1992-10-23
DK162090B (da)	1991-09-16
IE850684L (en)	1985-09-19
FI82449C (fi)	1991-03-11
LV5618A3 (lv)	1994-05-10
IL85130A (en)	1988-07-31
FI894540A0 (fi)	1989-09-26
YU43870B (en)	1989-12-31
PT80117A (en)	1985-04-01
JPH0561269B2 (fr)	1993-09-06
NO165799C (no)	1991-04-10
AU549927B2 (en)	1986-02-20
NZ211486A (en)	1988-10-28
PT80117B (pt)	1987-10-20
FI894540A (fi)	1989-09-26
RO90952A (fr)	1987-02-27
NO165799B (no)	1991-01-02
FI82449B (fi)	1990-11-30
SU1445556A3 (ru)	1988-12-15
NO851054L (no)	1985-09-20
FI82042B (fi)	1990-09-28
DK121385A (da)	1985-09-20
NZ224134A (en)	1988-10-28
AU4005985A (en)	1985-09-26
HUT37398A (en)	1985-12-28
GR850668B (fr)	1985-07-16
MY101987A (en)	1992-02-29
CS249539B2 (en)	1987-03-12
EG17795A (en)	1990-08-30
BG60347B2 (bg)	1994-09-30
EP0156603A3 (en)	1986-02-12
DK121385D0 (da)	1985-03-18
PH21323A (en)	1987-09-28
ES8603408A1 (es)	1985-12-16
MA20380A1 (fr)	1985-10-01
DE3572481D1 (en)	1989-09-28
IL85130A0 (en)	1988-06-30
IL74631A (en)	1988-07-31
CA1251441A (fr)	1989-03-21
NL940025I1 (nl)	1995-02-01
CA1288422C (fr)	1991-09-03
IE57743B1 (en)	1993-03-24
PH21470A (en)	1987-10-28
EP0156603A2 (fr)	1985-10-02
YU44085A (en)	1988-02-29
FI82042C (fi)	1991-01-10
UA6343A1 (uk)	1994-12-29
ZW4785A1 (en)	1985-06-19
US4556672A (en)	1985-12-03
PL145951B1 (en)	1988-12-31
SI8510440A8 (sl)	1996-06-30
KR850006173A (ko)	1985-10-02
CY1668A (en)	1993-05-14
ATE45731T1 (de)	1989-09-15
KR860001873B1 (ko)	1986-10-24
IL74631A0 (en)	1985-06-30
HU196178B (en)	1988-10-28
DK162090C (da)	1992-02-24
RO90952B (ro)	1987-03-01
FI851069L (fi)	1985-09-20
PL252434A1 (en)	1985-12-03
ES541372A0 (es)	1985-12-16
EP0156603B1 (fr)	1989-08-23
JPH04235165A (ja)	1992-08-24

Publication	Publication Date	Title
OA07966A (fr)	1987-01-31	Procédé de production d'un 2-oxindole-1-carboxamide et produit obtenu.
MX11031A (es)	1993-11-01	Proceso para la preparacion de nuevas 1-fenil-3-naftaleniloxipropanaminas producto obtenido y composicion farmaceutica que lo incluye.
HU904785D0 (en)	1992-03-30	Process for the production of medicaments
MX9202975A (es)	1992-07-01	Nuevos compuestos biciclicos y sus sales farmaceuticamente aceptables y procedimiento para su preparacion.
ES8603409A1 (es)	1985-12-16	Un procedimiento para la preparacion de un compuesto de 2-oxindol-1-carboxamida
HUT41740A (en)	1987-05-28	Process for production of new medically effective imidasolidins and medical preparatives containing thereof
IT1205640B (it)	1989-03-23	Nuovi composti ad attivita' antiinfiammatoria,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono
EP0191108A4 (fr)	1987-12-09	Composes de o-aminomethylphenol.