NL300599I2 - - Google Patents

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Publication number
NL300599I2
NL300599I2 NL300599C NL300599C NL300599I2 NL 300599 I2 NL300599 I2 NL 300599I2 NL 300599 C NL300599 C NL 300599C NL 300599 C NL300599 C NL 300599C NL 300599 I2 NL300599 I2 NL 300599I2
Authority
NL
Netherlands
Prior art keywords
bladder
rat
urination
rhythmic
measurement test
Prior art date
Application number
NL300599C
Other languages
English (en)
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32310425&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NL300599(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of NL300599I2 publication Critical patent/NL300599I2/nl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38Nitrogen atoms
    • C07D277/40Unsubstituted amino or imino radicals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NL300599C 2002-11-07 2013-06-20 NL300599I2 (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002323792 2002-11-07
PCT/JP2003/014065 WO2004041276A1 (ja) 2002-11-07 2003-11-04 酢酸アニリド誘導体を有効成分とする過活動膀胱治療剤

Publications (1)

Publication Number Publication Date
NL300599I2 true NL300599I2 (nl) 2017-01-03

Family

ID=32310425

Family Applications (1)

Application Number Title Priority Date Filing Date
NL300599C NL300599I2 (nl) 2002-11-07 2013-06-20

Country Status (28)

Country Link
US (5) US20060115540A1 (nl)
EP (1) EP1559427B1 (nl)
JP (1) JP3815496B2 (nl)
KR (1) KR100967070B1 (nl)
CN (1) CN100406011C (nl)
AT (1) ATE500827T1 (nl)
AU (1) AU2003284700B2 (nl)
BE (1) BE2013C040I2 (nl)
BR (1) BR0316080A (nl)
CA (1) CA2503570C (nl)
CY (2) CY1111399T1 (nl)
DE (1) DE60336334D1 (nl)
DK (1) DK1559427T3 (nl)
ES (1) ES2360353T3 (nl)
FR (1) FR13C0032I2 (nl)
HU (1) HUS1300027I1 (nl)
IL (1) IL168121A (nl)
LU (1) LU92218I2 (nl)
MX (1) MXPA05004925A (nl)
NL (1) NL300599I2 (nl)
NO (2) NO334948B1 (nl)
NZ (1) NZ539577A (nl)
PL (1) PL211687B1 (nl)
PT (1) PT1559427E (nl)
RU (1) RU2321401C2 (nl)
SI (1) SI1559427T1 (nl)
WO (1) WO2004041276A1 (nl)
ZA (1) ZA200503510B (nl)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
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DE10351271A1 (de) * 2003-10-31 2005-06-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pharmazeutische Zusammensetzung zur Behandlung der Stressinkontinenz und/oder Mischinkontinenz
EP2216021B1 (en) 2007-11-02 2012-10-17 Astellas Pharma Inc. Pharmaceutical composition for treating overactive bladder
JPWO2009081837A1 (ja) * 2007-12-21 2011-05-06 アステラス製薬株式会社 下部尿路症状の改善用医薬組成物
PE20091825A1 (es) * 2008-04-04 2009-12-04 Merck & Co Inc Hidroximetil pirrolidinas como agonistas del receptor adrenergico beta 3
TWI478712B (zh) 2008-09-30 2015-04-01 Astellas Pharma Inc 釋控性醫藥組成物
JP5553767B2 (ja) * 2008-11-07 2014-07-16 大日本住友製薬株式会社 新規で有用な下部尿路症状治療剤
US8586760B2 (en) * 2009-06-15 2013-11-19 Auspex Pharmaceuticals, Inc. Aminothiazole modulators of beta-3-adrenoreceptor
WO2011122524A1 (ja) 2010-03-29 2011-10-06 アステラス製薬株式会社 放出制御医薬組成物
JP5849946B2 (ja) * 2010-03-29 2016-02-03 アステラス製薬株式会社 放出制御医薬組成物
US9283210B2 (en) 2011-05-18 2016-03-15 Dr. Reddy's Laboratories Ltd. Amorphous mirabegron and processes for crystal forms of mirabegron
US9655885B2 (en) 2011-05-18 2017-05-23 Dr. Reddy's Laboratories Ltd. Amorphous mirabegron and processes for crystal forms of mirabegron
JPWO2013147134A1 (ja) 2012-03-30 2015-12-14 アステラス製薬株式会社 ミラベグロン含有医薬組成物
KR20150045500A (ko) 2012-08-31 2015-04-28 아스텔라스세이야쿠 가부시키가이샤 경구 투여용 의약 조성물
WO2014132270A2 (en) * 2013-02-27 2014-09-04 Msn Laboratories Limited Process for the preparation of 2-(2-aminothiazol-4-yl)-n-[4-(2-{[(2r)-2-hydroxy-2-phenyl ethyl]amino}ethyl)phenyl]acetamide monohydrochloride, its intermediates and polymorph thereof
CN103193730A (zh) * 2013-04-17 2013-07-10 苏州永健生物医药有限公司 一种米拉贝隆的合成方法
CN103232368B (zh) * 2013-04-18 2015-08-12 苏州永健生物医药有限公司 一种(r)-4-硝基苯乙基-(2-羟基-2-苯乙基)-氨基甲酸叔丁酯的合成方法
CN103193658A (zh) * 2013-04-18 2013-07-10 苏州永健生物医药有限公司 一种(r)-2-对硝基苯乙胺基-1-苯乙醇及其盐的合成方法
CN103232352B (zh) * 2013-05-11 2015-12-23 苏州永健生物医药有限公司 (r)-4-(2-(2-羟基-2-苯乙胺基)乙基)苯胺基甲酸叔丁基酯
JP2016525548A (ja) * 2013-07-23 2016-08-25 アラーガン、インコーポレイテッドAllergan,I� Β−3アドレナリン受容体刺激薬と組み合わせたデスモプレシンを含む方法及び組成物
ITMI20131653A1 (it) * 2013-10-07 2015-04-08 Dipharma Francis Srl Forme cristalline di un agonista adrenergico
RU2550968C1 (ru) * 2013-11-29 2015-05-20 Федеральное государственное бюджетное учреждение "Научный центр акушерства, гинекологии и перинатологии имени академика В.И. Кулакова" Министерства здравоохранения Российской Федерации Комплексный способ лечения пациенток с хроническими рецидивирующими циститами и рефрактерным гиперактивным мочевым пузырем
WO2015155664A1 (en) * 2014-04-08 2015-10-15 Suven Life Sciences Limited An improved process for the preparation of 2-(2-aminothiazol-4-yl)-n-[4-(2-[[(2r)-2-hydroxy-2- phenylethyl]amino]-ethyl)phenyl]acetamide
WO2015162536A1 (en) * 2014-04-22 2015-10-29 Calyx Chemicals And Pharmaceuticals Ltd. Novel process for preparation of mirabegron and it's intermediate
CN104016943A (zh) * 2014-05-23 2014-09-03 苏州凯瑞医药科技有限公司 一种米拉贝隆的合成方法
CN104016877B (zh) * 2014-06-13 2017-02-15 南京海融制药有限公司 一种苯基乙酰胺类化合物及在制备米拉贝隆中的应用
CN104230840A (zh) * 2014-09-05 2014-12-24 安徽联创药物化学有限公司 米拉贝隆的合成方法
KR20170097045A (ko) 2014-11-20 2017-08-25 알레간 인코포레이티드 알파-아드레날린성 수용체 길항제와 조합된 데스모프레신을 포함하는 방법 및 조성물
CN104496841B (zh) * 2014-11-26 2017-01-25 南京工业大学 一种米拉贝隆中间体的合成方法
CN104744292A (zh) * 2015-03-11 2015-07-01 南京工业大学 (r)-2-((4-硝基苯乙基)氨基)-2-氧代-1-苯乙基乙酸酯或其衍生物的制备方法
JP2018090490A (ja) 2015-03-31 2018-06-14 アステラス製薬株式会社 ミラベグロン含有医薬組成物
JP6618736B2 (ja) 2015-09-01 2019-12-11 沢井製薬株式会社 ミラベグロン含有錠剤、ミラベグロン含有製剤の製造方法及びミラベグロン含有造粒物の製造方法
CN106278909B (zh) * 2016-08-12 2022-07-15 浙江华海药业股份有限公司 一种米拉贝隆中间体的后处理方法
EP3360866B1 (en) 2017-02-14 2019-01-02 Alfred E. Tiefenbacher (GmbH & Co. KG) Mirabegron prodrugs
KR102051132B1 (ko) * 2017-03-17 2019-12-02 주식회사 종근당 미라베그론 또는 이의 염을 포함하는 방출조절용 약제학적 조성물
KR101868438B1 (ko) 2017-04-13 2018-06-20 (주) 성운파마코피아 아미드 유도체의 제조방법
JP7113434B2 (ja) 2017-05-31 2022-08-05 Sbiファーマ株式会社 過活動膀胱の予防剤または治療剤
KR102398639B1 (ko) 2017-06-20 2022-05-17 (주) 성운파마코피아 아미드 유도체의 염 및 그 제조방법
WO2019013583A2 (ko) 2017-07-14 2019-01-17 주식회사 대웅제약 약제학적 제제 및 그 제조방법
KR101937713B1 (ko) 2017-07-14 2019-01-14 주식회사 대웅제약 약제학적 제제 및 그 제조방법
KR20200117091A (ko) 2019-04-02 2020-10-14 제이투에이치바이오텍 (주) 미라베그론 전구체 약물 화합물 및 이의 과민성 방광 질환의 치료 또는 개선을 위한 의약 용도
EP3722285B1 (en) 2020-04-08 2022-03-30 Alfred E. Tiefenbacher (GmbH & Co. KG) Process for preparing mirabegron enacarbil
CN113816864B (zh) * 2020-06-18 2024-03-29 南京正大天晴制药有限公司 一种(r)-2-羟基-n-[2-(4-氨基苯基)乙基]-2-苯乙胺的制备方法
KR20220081033A (ko) 2020-12-08 2022-06-15 주식회사 한서켐 미라베그론 α형 결정의 제조방법
EP4338729A1 (en) 2022-09-19 2024-03-20 Sanovel Ilac Sanayi Ve Ticaret A.S. A tablet comprising mirabegron
EP4410279A1 (en) 2023-01-25 2024-08-07 Sanovel Ilac Sanayi Ve Ticaret A.S. A film tablet comprising mirabegron

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Also Published As

Publication number Publication date
NO20052691L (no) 2005-07-15
CA2503570C (en) 2011-04-19
PL376771A1 (pl) 2006-01-09
JPWO2004041276A1 (ja) 2006-03-02
JP3815496B2 (ja) 2006-08-30
NO2015001I2 (no) 2015-01-26
PT1559427E (pt) 2011-05-27
BE2013C040I2 (nl) 2023-03-07
LU92218I9 (nl) 2019-01-17
CN1711085A (zh) 2005-12-21
BR0316080A (pt) 2005-09-27
NO334948B1 (no) 2014-08-04
AU2003284700B2 (en) 2009-05-28
USRE44872E1 (en) 2014-04-29
RU2005117367A (ru) 2006-01-20
CA2503570A1 (en) 2004-05-21
IL168121A (en) 2011-12-29
US20090093529A1 (en) 2009-04-09
KR100967070B1 (ko) 2010-07-01
ES2360353T3 (es) 2011-06-03
CN100406011C (zh) 2008-07-30
DK1559427T3 (da) 2011-04-26
CY1111399T1 (el) 2015-08-05
ZA200503510B (en) 2006-12-27
EP1559427A4 (en) 2007-05-30
US20060115540A1 (en) 2006-06-01
ATE500827T1 (de) 2011-03-15
SI1559427T1 (sl) 2011-06-30
CY2013023I1 (el) 2015-10-07
RU2321401C2 (ru) 2008-04-10
AU2003284700A1 (en) 2004-06-07
NO20052691D0 (no) 2005-06-06
NZ539577A (en) 2007-06-29
CY2013023I2 (el) 2015-10-07
US8835474B2 (en) 2014-09-16
PL211687B1 (pl) 2012-06-29
NO2015001I1 (no) 2015-01-19
LU92218I2 (fr) 2014-01-07
FR13C0032I2 (fr) 2014-03-07
EP1559427A1 (en) 2005-08-03
US20110230530A1 (en) 2011-09-22
EP1559427B1 (en) 2011-03-09
US7750029B2 (en) 2010-07-06
HUS1300027I1 (hu) 2016-08-29
MXPA05004925A (es) 2005-08-18
WO2004041276A1 (ja) 2004-05-21
DE60336334D1 (de) 2011-04-21
KR20050072809A (ko) 2005-07-12
FR13C0032I1 (nl) 2013-08-09

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