MXPA04008077A - Anticuerpos ant-a° y su uso. - Google Patents

Anticuerpos ant-a° y su uso.

Info

Publication number
MXPA04008077A
MXPA04008077A MXPA04008077A MXPA04008077A MXPA04008077A MX PA04008077 A MXPA04008077 A MX PA04008077A MX PA04008077 A MXPA04008077 A MX PA04008077A MX PA04008077 A MXPA04008077 A MX PA04008077A MX PA04008077 A MXPA04008077 A MX PA04008077A
Authority
MX
Mexico
Prior art keywords
nucleic acid
antibody molecules
molecules
hosts
seq
Prior art date
Application number
MXPA04008077A
Other languages
English (en)
Inventor
Christine Rothe
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27741103&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MXPA04008077(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MXPA04008077A publication Critical patent/MXPA04008077A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0007—Nervous system antigens; Prions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Abstract

La presente invencion se refiere a moleculas de anticuerpos capaces de reconocer especificamente dos regiones del peptido °-A4, en donde la primera region comprende la secuencia de aminoacidos AEFRHDSGY como se muestra en la SEQ ID NO:1 o un fragmento de la misma y en donde la segunda region comprende la secuencia de aminoacidos VHHQKLVFFAEDVG como se muestra en la SEQ ID NO: 2 o un fragmentos de la misma. Ademas, se revelan molecula de acidos nucleicos que codifican las moleculas de anticuerpos de la invencion y vectores de huespedes que comprenden dichas moleculas de acidos nucleicos. Adicionalmente, la presente invencion provee composiciones, preferentemente composiciones farmaceuticas o de diagnostico que comprenden los compuestos de la invencion, asi como tambien usos especificos de las moleculas de anticuerpos, moleculas de acidos nucleicos, vectores o huespedes de la invencion.
MXPA04008077A 2002-02-20 2003-02-20 Anticuerpos ant-a° y su uso. MXPA04008077A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02003844 2002-02-20
PCT/EP2003/001759 WO2003070760A2 (en) 2002-02-20 2003-02-20 Anti-amyloid beta antibodies and their use

Publications (1)

Publication Number Publication Date
MXPA04008077A true MXPA04008077A (es) 2005-12-14

Family

ID=27741103

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA04008077A MXPA04008077A (es) 2002-02-20 2003-02-20 Anticuerpos ant-a° y su uso.

Country Status (27)

Country Link
US (4) US7794719B2 (es)
EP (2) EP1481008A2 (es)
JP (2) JP4383888B2 (es)
KR (1) KR101038828B1 (es)
CN (4) CN1630665A (es)
AR (2) AR038568A1 (es)
AU (1) AU2003218995B2 (es)
BR (1) BRPI0307837B8 (es)
CA (1) CA2477012C (es)
CL (1) CL2004001122A1 (es)
CO (1) CO5601037A2 (es)
CY (1) CY1118037T1 (es)
DK (1) DK2368907T3 (es)
ES (1) ES2590684T3 (es)
HR (1) HRP20040712B1 (es)
HU (1) HUE030591T2 (es)
IL (2) IL163563A0 (es)
LT (1) LT2368907T (es)
MX (1) MXPA04008077A (es)
NO (2) NO336112B1 (es)
NZ (1) NZ534522A (es)
PL (1) PL216190B1 (es)
PT (1) PT2368907T (es)
RU (1) RU2341533C2 (es)
SI (1) SI2368907T1 (es)
WO (1) WO2003070760A2 (es)
ZA (1) ZA200406604B (es)

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