MXPA02009339A - Plasmido recombinante capaz de liberarse en forma circular cerrada a partir de una secuencia nucleiotidica mas grande que permite la expresion especifica de sitio o la expresion regulada en el desarrollo de secuenicas geneticas seleccionadas. - Google Patents
Plasmido recombinante capaz de liberarse en forma circular cerrada a partir de una secuencia nucleiotidica mas grande que permite la expresion especifica de sitio o la expresion regulada en el desarrollo de secuenicas geneticas seleccionadas.Info
- Publication number
- MXPA02009339A MXPA02009339A MXPA02009339A MXPA02009339A MXPA02009339A MX PA02009339 A MXPA02009339 A MX PA02009339A MX PA02009339 A MXPA02009339 A MX PA02009339A MX PA02009339 A MXPA02009339 A MX PA02009339A MX PA02009339 A MXPA02009339 A MX PA02009339A
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8282—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for fungal resistance
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8202—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation by biological means, e.g. cell mediated or natural vector
- C12N15/8203—Virus mediated transformation
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8262—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield involving plant development
- C12N15/8263—Ablation; Apoptosis
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8279—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance
- C12N15/8283—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for biotic stress resistance, pathogen resistance, disease resistance for virus resistance
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- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
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- Organic Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Arrangement And Driving Of Transmission Devices (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente invencion se relaciona generalmente con plasmidos recombinantes y en particular plasmidos recombinantes geneticos que comprenden secuencias polinucleotidicas capaces de liberarse en forma circular, cerrada covalentemente a partir de una secuencia nucleotidica mas grande tal como, pero sin limitarse a un genoma de una celula eucariota. Preferiblemente, una vez liberada, la secuencia polinucleotidica se reconstituye en una forma que permite la expresion de la secuencia polinucleotidica. En una modalidad, la secuencia polinucleotidica reconstituida comprende una secuencia codificante con la totalidad o parte de un nucleotido extrano tal como, pero sin limitarse a una secuencia intronica u otra senal de maduracion insertada en la misma. La expresion y en particular la transcripcion de la secuencia codificante involucra la maduracion de la secuencia extrana. La liberacion y circularizacion generalmente es en respuesta a un estimulo tal como un estimulo mediado por una proteina. Mas particularmente, la proteina es una proteina viral o derivada de procariota o eucariota o bien una proteina regulada especifica por el desarrollo o por el tejido. El plasmido recombinante de la presente invencion es util particularmente para conferir resistencia genetica contra patogenos o inducir apoptosis u otros mecanismos de muerte celular utiles, por ejemplo, para tratar cancer o inducir esterilidad masculina o femenina en plantas. Los plasmidos recombinantes permiten, por lo tanto, expresion especifica de sitio o expresion regulada en el desarrollo de secuencias geneticas seleccionadas.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPQ6516A AUPQ651600A0 (en) | 2000-03-28 | 2000-03-28 | Suicide gene vector |
AUPR1081A AUPR108100A0 (en) | 2000-10-27 | 2000-10-27 | A construct |
PCT/AU2001/000349 WO2001072996A1 (en) | 2000-03-28 | 2001-03-28 | A construct capable of release in closed circular form from a larger nucleotide sequence permitting site specific expression and/or developmentally regulated expression of selected genetic sequences |
Publications (1)
Publication Number | Publication Date |
---|---|
MXPA02009339A true MXPA02009339A (es) | 2004-05-14 |
Family
ID=25646287
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MXPA02009339A MXPA02009339A (es) | 2000-03-28 | 2001-03-28 | Plasmido recombinante capaz de liberarse en forma circular cerrada a partir de una secuencia nucleiotidica mas grande que permite la expresion especifica de sitio o la expresion regulada en el desarrollo de secuenicas geneticas seleccionadas. |
Country Status (16)
Country | Link |
---|---|
US (2) | US7863430B2 (es) |
EP (1) | EP1282697B1 (es) |
JP (1) | JP4797141B2 (es) |
KR (1) | KR20030047880A (es) |
CN (1) | CN1426465B (es) |
AP (2) | AP1440A (es) |
AT (1) | ATE376589T1 (es) |
AU (1) | AU4393901A (es) |
BR (1) | BRPI0109522B8 (es) |
CA (1) | CA2404471C (es) |
DE (1) | DE60131075T2 (es) |
ES (1) | ES2296736T3 (es) |
MX (1) | MXPA02009339A (es) |
NZ (1) | NZ521488A (es) |
PT (1) | PT1282697E (es) |
WO (1) | WO2001072996A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102573514B (zh) | 2007-12-03 | 2015-01-07 | 先正达参股股份有限公司 | 工程化改造酶易感性肌醇六磷酸酶 |
WO2010099320A1 (en) * | 2009-02-25 | 2010-09-02 | University Of Hawaii | Plant resistance to banana bunchy top virus |
CA2912665C (en) | 2013-05-15 | 2021-03-02 | Robert Kruse | Intracellular translation of circular rna |
GB201402249D0 (en) | 2014-02-10 | 2014-03-26 | Vela Operations Pte Ltd | NGS systems control and methods involving the same |
WO2017136895A1 (en) * | 2016-02-10 | 2017-08-17 | Queensland University Of Technology | Constructs and methods for conferring virus resistance |
WO2019236673A1 (en) | 2018-06-06 | 2019-12-12 | Massachusetts Institute Of Technology | Circular rna for translation in eukaryotic cells |
CN115806976A (zh) * | 2019-03-20 | 2023-03-17 | 中国科学院上海营养与健康研究所 | 利用环形rna进行蛋白翻译及其应用 |
KR20220027855A (ko) | 2019-05-22 | 2022-03-08 | 매사추세츠 인스티튜트 오브 테크놀로지 | 원형 rna 조성물 및 방법 |
EP4289951A3 (en) | 2019-12-04 | 2024-03-13 | Orna Therapeutics, Inc. | Circular rna compositions and methods |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPN328595A0 (en) * | 1995-05-31 | 1995-06-22 | Queensland University Of Technology | Intergenic regions of banana bunchy top virus |
US6077992A (en) * | 1997-10-24 | 2000-06-20 | E. I. Du Pont De Nemours And Company | Binary viral expression system in plants |
EP1115870A2 (en) * | 1998-09-23 | 2001-07-18 | E.I. Du Pont De Nemours And Company | Binary viral expression system in plants |
-
2001
- 2001-03-28 EP EP01916742A patent/EP1282697B1/en not_active Expired - Lifetime
- 2001-03-28 ES ES01916742T patent/ES2296736T3/es not_active Expired - Lifetime
- 2001-03-28 JP JP2001570714A patent/JP4797141B2/ja not_active Expired - Fee Related
- 2001-03-28 CN CN01808621.7A patent/CN1426465B/zh not_active Expired - Lifetime
- 2001-03-28 AP APAP/P/2001/002105A patent/AP1440A/en active
- 2001-03-28 BR BRPI0109522A patent/BRPI0109522B8/pt not_active IP Right Cessation
- 2001-03-28 US US10/168,653 patent/US7863430B2/en not_active Expired - Fee Related
- 2001-03-28 WO PCT/AU2001/000349 patent/WO2001072996A1/en active IP Right Grant
- 2001-03-28 AT AT01916742T patent/ATE376589T1/de active
- 2001-03-28 PT PT01916742T patent/PT1282697E/pt unknown
- 2001-03-28 CA CA2404471A patent/CA2404471C/en not_active Expired - Fee Related
- 2001-03-28 AU AU4393901A patent/AU4393901A/xx active Pending
- 2001-03-28 AP APAP/P/2002/002636D patent/AP1645A/en active
- 2001-03-28 NZ NZ521488A patent/NZ521488A/en not_active IP Right Cessation
- 2001-03-28 KR KR1020027012740A patent/KR20030047880A/ko not_active Application Discontinuation
- 2001-03-28 DE DE60131075T patent/DE60131075T2/de not_active Expired - Lifetime
- 2001-03-28 MX MXPA02009339A patent/MXPA02009339A/es active IP Right Grant
-
2010
- 2010-11-17 US US12/948,005 patent/US8829170B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU4393901A (en) | 2001-10-08 |
CN1426465B (zh) | 2016-01-20 |
EP1282697A1 (en) | 2003-02-12 |
CA2404471A1 (en) | 2001-10-04 |
BR0109522A (pt) | 2003-06-10 |
NZ521488A (en) | 2004-07-30 |
ES2296736T3 (es) | 2008-05-01 |
BRPI0109522B1 (pt) | 2015-12-08 |
PT1282697E (pt) | 2008-02-01 |
JP4797141B2 (ja) | 2011-10-19 |
WO2001072996A1 (en) | 2001-10-04 |
EP1282697B1 (en) | 2007-10-24 |
US20110119782A1 (en) | 2011-05-19 |
DE60131075D1 (de) | 2007-12-06 |
BRPI0109522B8 (pt) | 2017-04-11 |
JP2003528606A (ja) | 2003-09-30 |
US8829170B2 (en) | 2014-09-09 |
DE60131075T2 (de) | 2008-07-31 |
US7863430B2 (en) | 2011-01-04 |
ATE376589T1 (de) | 2007-11-15 |
CA2404471C (en) | 2010-09-28 |
EP1282697A4 (en) | 2004-06-23 |
CN1426465A (zh) | 2003-06-25 |
US20040121430A1 (en) | 2004-06-24 |
AP1645A (en) | 2006-07-28 |
AP1440A (en) | 2005-06-28 |
KR20030047880A (ko) | 2003-06-18 |
AP2002002636A0 (en) | 2002-09-30 |
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