MX315904B - Inhibidores de fosfoinosituro-3 cinasa. - Google Patents
Inhibidores de fosfoinosituro-3 cinasa.Info
- Publication number
- MX315904B MX315904B MX2010013110A MX2010013110A MX315904B MX 315904 B MX315904 B MX 315904B MX 2010013110 A MX2010013110 A MX 2010013110A MX 2010013110 A MX2010013110 A MX 2010013110A MX 315904 B MX315904 B MX 315904B
- Authority
- MX
- Mexico
- Prior art keywords
- kinase
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5774508P | 2008-05-30 | 2008-05-30 | |
| PCT/US2009/045713 WO2009155121A2 (en) | 2008-05-30 | 2009-05-29 | Inhibitors of pi3 kinase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2010013110A MX2010013110A (es) | 2010-12-20 |
| MX315904B true MX315904B (es) | 2013-11-29 |
Family
ID=40902593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010013110A MX315904B (es) | 2008-05-30 | 2009-05-29 | Inhibidores de fosfoinosituro-3 cinasa. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US8415376B2 (es) |
| EP (1) | EP2307400B1 (es) |
| JP (1) | JP5599783B2 (es) |
| AU (1) | AU2009260447B2 (es) |
| CA (1) | CA2725014C (es) |
| ES (1) | ES2474147T3 (es) |
| MX (1) | MX315904B (es) |
| WO (1) | WO2009155121A2 (es) |
Families Citing this family (56)
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| US8415376B2 (en) | 2008-05-30 | 2013-04-09 | Amgen Inc. | Inhibitors of PI3 kinase |
| AU2010226490A1 (en) | 2009-03-20 | 2011-10-06 | Amgen Inc. | Inhibitors of PI3 kinase |
| WO2011026579A1 (en) * | 2009-09-04 | 2011-03-10 | Bayer Schering Pharma Aktiengesellschaft | Substituted aminoquinoxalines as tyrosine threonine kinase inhibitors |
| RU2012146246A (ru) | 2010-03-31 | 2014-05-10 | Актелион Фармасьютиклз Лтд | Антибактериальные производные изохинолин-3-илмочевины |
| JO2998B1 (ar) | 2010-06-04 | 2016-09-05 | Amgen Inc | مشتقات بيبيريدينون كمثبطات mdm2 لعلاج السرطان |
| AR088729A1 (es) | 2011-03-29 | 2014-07-02 | Actelion Pharmaceuticals Ltd | Derivados de 3-ureidoisoquinolin-8-ilo y una composicion farmaceutica |
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| AU2012316055B2 (en) | 2011-09-27 | 2016-05-12 | Amgen Inc. | Heterocyclic compounds as MDM2 inhibitors for the treatment of cancer |
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| WO2014022128A1 (en) * | 2012-07-29 | 2014-02-06 | Calitor Sciences, Llc | Pi3 kinase modulators and methods of use |
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| CN104016979B (zh) * | 2012-11-23 | 2017-05-03 | 广东东阳光药业有限公司 | 取代的环化合物及其使用方法和用途 |
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| CN105859684B (zh) * | 2016-04-15 | 2017-03-22 | 四川赛诺唯新生物技术有限公司 | 一种稠环化合物、其制备方法和应用及其中间体化合物 |
| AU2017291838B2 (en) * | 2016-07-06 | 2021-01-28 | The Regents Of The University Of Michigan | Multifunctional inhibitors of MEK/PI3K and mTOR/MEK/PI3K biological pathways and therapeutic methods using the same |
| TW201825465A (zh) | 2016-09-23 | 2018-07-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| TW201813963A (zh) | 2016-09-23 | 2018-04-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| TW201815787A (zh) | 2016-09-23 | 2018-05-01 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| JOP20190272A1 (ar) | 2017-05-22 | 2019-11-21 | Amgen Inc | مثبطات kras g12c وطرق لاستخدامها |
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| US11311624B2 (en) * | 2017-08-11 | 2022-04-26 | The Regents Of The University Of Michigan | Inhibitors of MEK/PI3K, JAK/MEK, JAK/PI3K/mTOR and MEK/PI3K/mTOR biological pathways and methods for improving lymphatic uptake, bioavailability, and solubility of therapeutic compounds |
| CN108373462A (zh) * | 2017-12-22 | 2018-08-07 | 西安交通大学 | 6-（吡啶-4-基）-4-取代氨基的喹唑啉或喹啉类化合物及其应用 |
| CN111936469A (zh) * | 2018-04-06 | 2020-11-13 | 日本曹达株式会社 | (杂)芳基磺酰胺化合物和有害生物防除剂 |
| CA3098574A1 (en) | 2018-05-04 | 2019-11-07 | Amgen Inc. | Kras g12c inhibitors and methods of using the same |
| JP2021527125A (ja) * | 2018-06-07 | 2021-10-11 | ディサーム・セラピューティクス・インコーポレイテッドＤｉｓａｒｍ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． | Ｓａｒｍ１阻害剤 |
| CA3116313A1 (en) * | 2018-10-17 | 2020-04-23 | Purdue Research Foundation | Fibroblast activation protein (fap) targeted imaging and therapy in fibrosis |
| JP7377679B2 (ja) | 2018-11-19 | 2023-11-10 | アムジエン・インコーポレーテツド | がん治療のためのｋｒａｓｇ１２ｃ阻害剤及び１種以上の薬学的に活性な追加の薬剤を含む併用療法 |
| EP3738593A1 (en) | 2019-05-14 | 2020-11-18 | Amgen, Inc | Dosing of kras inhibitor for treatment of cancers |
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| EA201270013A1 (ru) | 2009-06-25 | 2012-06-29 | Амген Инк. | Гетероциклические соединения и их применение |
| EP2445902A2 (en) | 2009-06-25 | 2012-05-02 | Amgen, Inc | Heterocyclic compounds and their uses as inhibitors of pi3k activity |
| US8399460B2 (en) | 2009-10-27 | 2013-03-19 | Astrazeneca Ab | Chromenone derivatives |
| EA027123B1 (ru) | 2009-11-05 | 2017-06-30 | Ризен Фармасьютикалз С.А. | Ингибиторы киназы pi3k |
| WO2011058113A1 (en) | 2009-11-12 | 2011-05-19 | Ucb Pharma S.A. | Fused bicyclic pyridine and pyrazine derivatives as kinase inhibitors |
| WO2011058108A1 (en) | 2009-11-12 | 2011-05-19 | Ucb Pharma S.A. | Quinoline and quinoxaline derivatives as kinase inhibitors |
-
2009
- 2009-05-29 US US12/995,431 patent/US8415376B2/en active Active
- 2009-05-29 WO PCT/US2009/045713 patent/WO2009155121A2/en active Application Filing
- 2009-05-29 MX MX2010013110A patent/MX315904B/es active IP Right Grant
- 2009-05-29 CA CA2725014A patent/CA2725014C/en not_active Expired - Fee Related
- 2009-05-29 AU AU2009260447A patent/AU2009260447B2/en not_active Ceased
- 2009-05-29 ES ES09767432.9T patent/ES2474147T3/es active Active
- 2009-05-29 EP EP09767432.9A patent/EP2307400B1/en active Active
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Also Published As
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|---|---|
| WO2009155121A3 (en) | 2010-02-18 |
| CA2725014A1 (en) | 2009-12-23 |
| JP2011522806A (ja) | 2011-08-04 |
| US8415376B2 (en) | 2013-04-09 |
| JP5599783B2 (ja) | 2014-10-01 |
| EP2307400A2 (en) | 2011-04-13 |
| US20110092504A1 (en) | 2011-04-21 |
| AU2009260447B2 (en) | 2012-03-29 |
| WO2009155121A2 (en) | 2009-12-23 |
| MX2010013110A (es) | 2010-12-20 |
| AU2009260447A1 (en) | 2009-12-23 |
| ES2474147T3 (es) | 2014-07-08 |
| CA2725014C (en) | 2014-06-17 |
| EP2307400B1 (en) | 2014-04-23 |
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