MX2010007818A - Terapia combinada que comprende inhibidores de co-transportadores de glucosa de sodio e inhibidores de dipeptidil peptidasa 4. - Google Patents

Terapia combinada que comprende inhibidores de co-transportadores de glucosa de sodio e inhibidores de dipeptidil peptidasa 4.

Info

Publication number
MX2010007818A
MX2010007818A MX2010007818A MX2010007818A MX2010007818A MX 2010007818 A MX2010007818 A MX 2010007818A MX 2010007818 A MX2010007818 A MX 2010007818A MX 2010007818 A MX2010007818 A MX 2010007818A MX 2010007818 A MX2010007818 A MX 2010007818A
Authority
MX
Mexico
Prior art keywords
inhibitors
combination therapy
sglt
dpp4
combination
Prior art date
Application number
MX2010007818A
Other languages
English (en)
Inventor
Kenji Arakawa
Kiichiro Ueta
Yasuaki Matsushita
Original Assignee
Mitsubishi Tanabe Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40433628&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2010007818(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Mitsubishi Tanabe Pharma Corp filed Critical Mitsubishi Tanabe Pharma Corp
Publication of MX2010007818A publication Critical patent/MX2010007818A/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/401—Proline; Derivatives thereof, e.g. captopril
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
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    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • A—HUMAN NECESSITIES
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    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/04—Carbocyclic radicals

Abstract

La presente invención hace referencia a una terapia combinada que comprende un inhibidor de DPP4 y un inhibidor de SGLT; la combinación de la presente invención deriva en el aumento del nivel de GLP-1 en plasma y, dicha combinación es útil para la prevención o tratamiento de afecciones tal como diabetes y enfermedades relacionadas con diabetes.
MX2010007818A 2008-01-17 2009-01-16 Terapia combinada que comprende inhibidores de co-transportadores de glucosa de sodio e inhibidores de dipeptidil peptidasa 4. MX2010007818A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2177708P 2008-01-17 2008-01-17
PCT/JP2009/051023 WO2009091082A1 (en) 2008-01-17 2009-01-16 Combination therapy comprising sglt inhibitors and dpp4 inhibitors

Publications (1)

Publication Number Publication Date
MX2010007818A true MX2010007818A (es) 2010-08-09

Family

ID=40433628

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010007818A MX2010007818A (es) 2008-01-17 2009-01-16 Terapia combinada que comprende inhibidores de co-transportadores de glucosa de sodio e inhibidores de dipeptidil peptidasa 4.

Country Status (14)

Country Link
US (2) US8853385B2 (es)
EP (1) EP2252289B1 (es)
JP (3) JP5204849B2 (es)
KR (1) KR101257554B1 (es)
CN (2) CN103599539A (es)
AR (1) AR070193A1 (es)
AU (1) AU2009205060C1 (es)
BR (1) BRPI0906735A2 (es)
CA (1) CA2712614C (es)
CL (1) CL2008003653A1 (es)
ES (1) ES2763239T3 (es)
MX (1) MX2010007818A (es)
TW (1) TWI437996B (es)
WO (1) WO2009091082A1 (es)

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JP2015044845A (ja) 2015-03-12
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AR070193A1 (es) 2010-03-17
WO2009091082A1 (en) 2009-07-23
CA2712614C (en) 2014-05-27
RU2010134362A (ru) 2012-02-27
KR101257554B1 (ko) 2013-04-23
CN101932321B (zh) 2016-05-18
AU2009205060B2 (en) 2013-06-27
BRPI0906735A2 (pt) 2015-07-07
AU2009205060C1 (en) 2013-12-19
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US8853385B2 (en) 2014-10-07
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US20140371162A1 (en) 2014-12-18
TWI437996B (zh) 2014-05-21
JP5908563B2 (ja) 2016-04-26
AU2009205060A1 (en) 2009-07-23
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