MX2010006166A - Compuestos amida como refuerzos de antivirales. - Google Patents
Compuestos amida como refuerzos de antivirales.Info
- Publication number
- MX2010006166A MX2010006166A MX2010006166A MX2010006166A MX2010006166A MX 2010006166 A MX2010006166 A MX 2010006166A MX 2010006166 A MX2010006166 A MX 2010006166A MX 2010006166 A MX2010006166 A MX 2010006166A MX 2010006166 A MX2010006166 A MX 2010006166A
- Authority
- MX
- Mexico
- Prior art keywords
- boosters
- compounds
- antivirals
- amide compounds
- certain drugs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/82—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Abstract
La presente invención se refiere a compuestos que tienen propiedades inhibidoras de CYP45O y por lo tanto son útiles como refuerzos de determinados fármacos, es decir, son capaces de aumentar por lo menos una de las variables farmacocinéticas de determinados fármacos cuando se co-administran; la invención proporciona además el uso de dichos compuestos como mejoradores de la biodisponibilidad de determinados fármacos; además se proporcionan métodos para la preparación de los compuestos de la invención y composiciones farmacéuticas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07122468 | 2007-12-06 | ||
PCT/EP2008/066847 WO2009071650A2 (en) | 2007-12-06 | 2008-12-05 | Amide compounds as boosters of antivirals |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010006166A true MX2010006166A (es) | 2010-10-05 |
Family
ID=39386111
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010006166A MX2010006166A (es) | 2007-12-06 | 2008-12-05 | Compuestos amida como refuerzos de antivirales. |
Country Status (24)
Country | Link |
---|---|
US (1) | US8350048B2 (es) |
EP (1) | EP2235008B1 (es) |
JP (1) | JP5509092B2 (es) |
KR (1) | KR101624675B1 (es) |
CN (1) | CN101878210B (es) |
AP (1) | AP2804A (es) |
AR (1) | AR069595A1 (es) |
AU (1) | AU2008333165B2 (es) |
BR (1) | BRPI0821021A2 (es) |
CA (1) | CA2706155C (es) |
CL (1) | CL2008003639A1 (es) |
EA (1) | EA019616B1 (es) |
HK (1) | HK1149553A1 (es) |
IL (1) | IL205489A (es) |
MX (1) | MX2010006166A (es) |
MY (1) | MY151005A (es) |
NZ (1) | NZ585652A (es) |
PA (1) | PA8806801A1 (es) |
PE (1) | PE20091263A1 (es) |
TW (1) | TWI438202B (es) |
UA (1) | UA103013C2 (es) |
UY (1) | UY31513A1 (es) |
WO (1) | WO2009071650A2 (es) |
ZA (1) | ZA201004025B (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2009301131B2 (en) * | 2008-10-07 | 2014-03-27 | Janssen Sciences Ireland Uc | New amide compounds as boosters of antivirals |
US20120172368A1 (en) * | 2009-09-03 | 2012-07-05 | Koen Vandyck | Bis-Benzimidazole Derivatives |
US8759535B2 (en) | 2010-02-18 | 2014-06-24 | High Point Pharmaceuticals, Llc | Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof |
CA2833006A1 (en) * | 2011-04-22 | 2012-10-26 | Merck Sharp & Dohme Corp. | Taste-masked formulations of raltegravir |
WO2014194519A1 (en) | 2013-06-07 | 2014-12-11 | Merck Sharp & Dohme Corp. | Imidazole derivatives and methods of use thereof for improving pharmacokinetics of drug |
CN104000824B (zh) * | 2014-05-28 | 2016-07-06 | 中山大学 | 苯并五元杂环类化合物在制备抗hiv-1病毒药物中的应用 |
WO2016089648A1 (en) | 2014-12-01 | 2016-06-09 | Vtv Therapeutics Llc | Bach 1 inhibitors in combination with nrf2 activators and pharmaceutical compositions thereof |
CN105985356B (zh) * | 2015-02-05 | 2018-06-22 | 四川大学 | 咪唑[2,1-b]噻唑衍生物及其制备方法和用途 |
AU2016375634B2 (en) | 2015-12-22 | 2021-03-25 | Kancera Ab | Bicyclic hydroxamic acids useful as inhibitors of mammalian histone deacetylase activity |
AR114136A1 (es) | 2017-10-10 | 2020-07-29 | Hoffmann La Roche | Compuestos heterocíclicos |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6037157A (en) * | 1995-06-29 | 2000-03-14 | Abbott Laboratories | Method for improving pharmacokinetics |
AR037797A1 (es) | 2001-12-12 | 2004-12-01 | Tibotec Pharm Ltd | Combinacion de inhibidores de proteasa dependientes del citocromo p450 |
MY142238A (en) | 2002-03-12 | 2010-11-15 | Tibotec Pharm Ltd | Broadspectrum substituted benzimidazole sulfonamide hiv protease inhibitors |
CN101445493A (zh) * | 2002-08-02 | 2009-06-03 | 泰博特克药品有限公司 | 广谱2-氨基-苯并噻唑磺酰胺类hiv蛋白酶抑制剂 |
AR053845A1 (es) * | 2005-04-15 | 2007-05-23 | Tibotec Pharm Ltd | 5-tiazolilmetil[(1s,2r)-3-[[(2-amino-6-benzoxazolil)sulfonil)](2-metilpropil)amino]-2-hidroxi-1-(fenilmetil)propil]carbamato como mejorador de farmacos metabolizados por el citocromo p450 |
WO2008022345A2 (en) * | 2006-08-18 | 2008-02-21 | Sequoia Pharmaceuticals, Inc. | Compositions and methods for inhibiting cytochrome p450 |
-
2008
- 2008-05-12 UA UAA201006463A patent/UA103013C2/uk unknown
- 2008-12-05 TW TW097147227A patent/TWI438202B/zh not_active IP Right Cessation
- 2008-12-05 KR KR1020107013595A patent/KR101624675B1/ko not_active IP Right Cessation
- 2008-12-05 JP JP2010536465A patent/JP5509092B2/ja not_active Expired - Fee Related
- 2008-12-05 CL CL2008003639A patent/CL2008003639A1/es unknown
- 2008-12-05 MY MYPI20102496 patent/MY151005A/en unknown
- 2008-12-05 CN CN2008801182809A patent/CN101878210B/zh not_active Expired - Fee Related
- 2008-12-05 EA EA201070691A patent/EA019616B1/ru not_active IP Right Cessation
- 2008-12-05 PA PA20088806801A patent/PA8806801A1/es unknown
- 2008-12-05 AU AU2008333165A patent/AU2008333165B2/en not_active Ceased
- 2008-12-05 WO PCT/EP2008/066847 patent/WO2009071650A2/en active Application Filing
- 2008-12-05 AR ARP080105313A patent/AR069595A1/es unknown
- 2008-12-05 CA CA2706155A patent/CA2706155C/en active Active
- 2008-12-05 PE PE2008002023A patent/PE20091263A1/es not_active Application Discontinuation
- 2008-12-05 MX MX2010006166A patent/MX2010006166A/es active IP Right Grant
- 2008-12-05 UY UY31513A patent/UY31513A1/es unknown
- 2008-12-05 NZ NZ585652A patent/NZ585652A/en not_active IP Right Cessation
- 2008-12-05 AP AP2010005285A patent/AP2804A/xx active
- 2008-12-05 EP EP08855867.1A patent/EP2235008B1/en active Active
- 2008-12-05 US US12/745,334 patent/US8350048B2/en active Active
- 2008-12-05 BR BRPI0821021-7A patent/BRPI0821021A2/pt not_active IP Right Cessation
-
2010
- 2010-05-02 IL IL205489A patent/IL205489A/en not_active IP Right Cessation
- 2010-06-04 ZA ZA2010/04025A patent/ZA201004025B/en unknown
-
2011
- 2011-04-13 HK HK11103719.1A patent/HK1149553A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration |