MX2010003155A - Derivados de ciclopropil aril amida y uso de los mismos. - Google Patents

Derivados de ciclopropil aril amida y uso de los mismos.

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Publication number
MX2010003155A
MX2010003155A MX2010003155A MX2010003155A MX2010003155A MX 2010003155 A MX2010003155 A MX 2010003155A MX 2010003155 A MX2010003155 A MX 2010003155A MX 2010003155 A MX2010003155 A MX 2010003155A MX 2010003155 A MX2010003155 A MX 2010003155A
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Mexico
Prior art keywords
sup
amide derivatives
aryl amide
cyclopropyl aryl
cyclopropyl
Prior art date
Application number
MX2010003155A
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English (en)
Inventor
David Nigel Hurst
David Bernard Smith
Daisy Joe Du Bois
David Garrett Loughhead
Hans Maag
Jason Manka
Original Assignee
Hoffmann La Roche
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Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MX2010003155A publication Critical patent/MX2010003155A/es

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    • C07C235/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/42Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton
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    • C07C233/00Carboxylic acid amides
    • C07C233/64Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C233/65Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
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    • C07C233/66Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
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    • C07C233/74Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
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    • C07C235/44Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
    • C07C235/54Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
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Abstract

La presente invenci?n se refiere a compuestos de la f?rmula (I) en donde Ar1, Ar2, R1 y R2 son como se definieron aqu?. Tambi?n se proporcionan composiciones farmac?uticas, m?todos de uso, y m?todos de preparaci?n de los compuestos objetivo. (ver f?rmula).
MX2010003155A 2007-10-04 2008-09-25 Derivados de ciclopropil aril amida y uso de los mismos. MX2010003155A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99758107P 2007-10-04 2007-10-04
PCT/EP2008/062813 WO2009043784A1 (en) 2007-10-04 2008-09-25 Cyclopropyl aryl amide derivatives and uses thereof

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MX2010003155A true MX2010003155A (es) 2010-04-01

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US (1) US7723391B2 (es)
EP (1) EP2207540B1 (es)
JP (1) JP5362729B2 (es)
KR (1) KR101178674B1 (es)
CN (1) CN101815512B (es)
AU (1) AU2008307195B2 (es)
CA (1) CA2699625C (es)
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CA2699625A1 (en) 2009-04-09
KR20100053677A (ko) 2010-05-20
JP2010540586A (ja) 2010-12-24
CN101815512B (zh) 2013-04-24
AU2008307195B2 (en) 2012-11-22
US20090093525A1 (en) 2009-04-09
JP5362729B2 (ja) 2013-12-11
KR101178674B1 (ko) 2012-08-30
EP2207540B1 (en) 2014-02-26
WO2009043784A1 (en) 2009-04-09
CA2699625C (en) 2016-02-02
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IL204437A (en) 2013-09-30
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