MX2009004813A - Derivados de azaadamantano y sus usos como ligandos de receptores de acetilcolina nicotinicos. - Google Patents

Derivados de azaadamantano y sus usos como ligandos de receptores de acetilcolina nicotinicos.

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Publication number
MX2009004813A
MX2009004813A MX2009004813A MX2009004813A MX2009004813A MX 2009004813 A MX2009004813 A MX 2009004813A MX 2009004813 A MX2009004813 A MX 2009004813A MX 2009004813 A MX2009004813 A MX 2009004813A MX 2009004813 A MX2009004813 A MX 2009004813A
Authority
MX
Mexico
Prior art keywords
methods
compounds
azaadamantane derivatives
derivatives
azaadamantane
Prior art date
Application number
MX2009004813A
Other languages
English (en)
Inventor
William H Bunnelle
Diana L Nersesian
Lei Shi
Jianguo Ji
Michael R Schrimpf
Tao Li
Kevin B Sippy
Rodger F Henry
Shuang Chen
Chih-Hung Lee
Marc Scanio
Geoff G Z Zhang
Paul J Brackemeyer
Original Assignee
Abbott Lab
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39594848&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009004813(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of MX2009004813A publication Critical patent/MX2009004813A/es

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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/4965—Non-condensed pyrazines
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    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
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    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C07F5/022—Boron compounds without C-boron linkages

Abstract

La invención se refiere a compuestos que son derivados de azaadamantano de la fórmula (I), particularmente derivados de azaadamantano sustituidos con éter o amina, y sales y profármacos de éstos, a composiciones que comprenden estos compuestos, a métodos para usar estos compuestos y composiciones, a procesos para preparar estos compuestos, y a intermediarios obtenidos durante tales procesos.
MX2009004813A 2006-11-06 2007-11-06 Derivados de azaadamantano y sus usos como ligandos de receptores de acetilcolina nicotinicos. MX2009004813A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US85699206P 2006-11-06 2006-11-06
US90814307P 2007-03-26 2007-03-26
US11/935,157 US8314119B2 (en) 2006-11-06 2007-11-05 Azaadamantane derivatives and methods of use
PCT/US2007/083687 WO2008058096A2 (en) 2006-11-06 2007-11-06 Azaadamantane derivatives and their uses as nicotinic acetylcholine receptors ligands

Publications (1)

Publication Number Publication Date
MX2009004813A true MX2009004813A (es) 2009-07-31

Family

ID=39594848

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2012005921A MX340064B (es) 2006-11-06 2007-11-06 Derivados de azaadamantano y sus usos como ligandos de receptores de acetilcolina nicotinicos.
MX2009004813A MX2009004813A (es) 2006-11-06 2007-11-06 Derivados de azaadamantano y sus usos como ligandos de receptores de acetilcolina nicotinicos.

Family Applications Before (1)

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MX2012005921A MX340064B (es) 2006-11-06 2007-11-06 Derivados de azaadamantano y sus usos como ligandos de receptores de acetilcolina nicotinicos.

Country Status (29)

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US (3) US8314119B2 (es)
EP (1) EP2099795B1 (es)
JP (4) JP5275246B2 (es)
KR (4) KR20140054300A (es)
CN (1) CN103554107B (es)
AU (1) AU2007316480B2 (es)
BR (1) BRPI0718028A2 (es)
CA (1) CA2668962C (es)
CO (1) CO6210720A2 (es)
CR (2) CR10743A (es)
DK (1) DK2099795T3 (es)
DO (3) DOP2011000301A (es)
EC (1) ECSP099388A (es)
ES (1) ES2551117T3 (es)
HK (1) HK1133645A1 (es)
IL (2) IL198587A (es)
MX (2) MX340064B (es)
MY (1) MY148253A (es)
NO (1) NO20092181L (es)
NZ (4) NZ600178A (es)
PH (1) PH12013500745A1 (es)
PL (1) PL2099795T3 (es)
PT (1) PT2099795E (es)
RU (2) RU2450002C2 (es)
SG (1) SG176473A1 (es)
TW (1) TWI511729B (es)
UA (1) UA96961C2 (es)
WO (1) WO2008058096A2 (es)
ZA (3) ZA200903944B (es)

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