MX2011014019A - Derivados de diazahomoadamantano y sus metodos de uso. - Google Patents
Derivados de diazahomoadamantano y sus metodos de uso.Info
- Publication number
- MX2011014019A MX2011014019A MX2011014019A MX2011014019A MX2011014019A MX 2011014019 A MX2011014019 A MX 2011014019A MX 2011014019 A MX2011014019 A MX 2011014019A MX 2011014019 A MX2011014019 A MX 2011014019A MX 2011014019 A MX2011014019 A MX 2011014019A
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- diazahomoadamantane
- derivatives
- diazahomoadamantane derivatives
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
La invención se refiere a compuestos que son derivados de diazahomoadamantano, composiciones que comprenden tales compuestos, y métodos para utilizar tales compuestos y composiciones.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21847909P | 2009-06-19 | 2009-06-19 | |
PCT/CN2010/000889 WO2010145208A1 (en) | 2009-06-19 | 2010-06-18 | Diazahomoadamantane derivatives and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2011014019A true MX2011014019A (es) | 2012-02-22 |
Family
ID=43354879
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2011014019A MX2011014019A (es) | 2009-06-19 | 2010-06-18 | Derivados de diazahomoadamantano y sus metodos de uso. |
Country Status (15)
Country | Link |
---|---|
US (1) | US8846661B2 (es) |
EP (1) | EP2443122B1 (es) |
JP (1) | JP2012530084A (es) |
KR (1) | KR20120044978A (es) |
CN (1) | CN102459268A (es) |
AU (1) | AU2010262643B2 (es) |
BR (1) | BRPI1015043A2 (es) |
CA (1) | CA2765466A1 (es) |
IL (2) | IL216883A (es) |
MX (1) | MX2011014019A (es) |
NZ (1) | NZ597511A (es) |
PE (1) | PE20121066A1 (es) |
RU (2) | RU2549551C2 (es) |
SG (1) | SG176921A1 (es) |
WO (1) | WO2010145208A1 (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2011291579B2 (en) | 2010-08-20 | 2016-11-10 | Research Triangle Institute | Nicotinic receptor compounds |
CN103087001A (zh) * | 2011-11-03 | 2013-05-08 | 南京大学 | 香草酸的1,3,4-噁二唑衍生物及其制法和用途 |
WO2014165090A1 (en) * | 2013-03-13 | 2014-10-09 | The Broad Institute, Inc. | Compounds for the treatment of tuberculosis |
RU2552649C1 (ru) * | 2013-12-13 | 2015-06-10 | Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Московский государственный университет тонких химических технологий имени М.В. Ломоносова" (МИТХТ им. М.В. Ломоносова) | Душистые 5-бензил-1,3-диазаадамантан-6-оны |
WO2015103005A1 (en) * | 2014-01-03 | 2015-07-09 | Research Institute At Nationwide Children's Hospital | Amphiphilic amine compounds and their use as therapeutic agents and nanocarriers |
ES2764660T3 (es) | 2014-12-16 | 2020-06-04 | Axovant Sciences Gmbh | Compuestos de amida de quinuclidina sustituida geminal como agonistas de receptores alfa-7 nicotínicos de acetilcolina |
WO2016201096A1 (en) | 2015-06-10 | 2016-12-15 | Forum Pharmaceuticals, Inc. | Aminobenzisoxazole compounds as agonists of a7-nicotinic acetylcholine receptors |
EP3334740A4 (en) | 2015-08-12 | 2019-02-06 | Axovant Sciences GmbH | GEMINAL SUBSTITUTED AMINOBENZISOXAZOLE COMPOUNDS AS AGONISTS OF ALPHA 7-NICOTINIC ACETYLCHOLINE RECEPTORS |
CN113750101A (zh) | 2015-12-10 | 2021-12-07 | Ptc医疗公司 | 用于治疗亨廷顿病的方法 |
SG11201911615WA (en) | 2017-06-05 | 2020-01-30 | Ptc Therapeutics Inc | Compounds for treating huntington's disease |
CA3067592A1 (en) | 2017-06-28 | 2019-01-03 | Ptc Therapeutics, Inc. | Methods for treating huntington's disease |
MX2019015578A (es) | 2017-06-28 | 2020-07-28 | Ptc Therapeutics Inc | Metodos para tratar la enfermedad de huntington. |
EP3749666A1 (en) * | 2018-02-08 | 2020-12-16 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Heteroaryl compounds, pharmaceutical compositions thereof, and their therapeutic use |
MX2020009957A (es) | 2018-03-27 | 2021-01-15 | Ptc Therapeutics Inc | Compuestos para el tratamiento de enfermedad de hungtinton. |
US11685746B2 (en) | 2018-06-27 | 2023-06-27 | Ptc Therapeutics, Inc. | Heteroaryl compounds for treating Huntington's disease |
PE20211378A1 (es) | 2018-06-27 | 2021-07-27 | Ptc Therapeutics Inc | Compuestos heterociclicos y de heteroarilo para tratar la enfermedad de huntington |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4557865A (en) * | 1984-05-07 | 1985-12-10 | Pennwalt Corporation | Substituted 4-azatricyclo[4.3.1.13,8 ]undecane compounds |
AU702720B2 (en) * | 1995-11-02 | 1999-03-04 | Neurosearch A/S | Fused tropane-derivatives as neurotransmitter reuptake inhibitors |
PL346247A1 (en) * | 1998-08-18 | 2002-01-28 | Ucb Sa | Muscarinic agonists and antagonists |
CA2348879A1 (en) * | 1998-11-02 | 2000-05-11 | Welfide Corporation | Pyrrolidine compound and pharmaceutical use thereof |
JP2005505506A (ja) * | 2001-06-12 | 2005-02-24 | イーラン ファーマスーティカルズ、インコーポレイテッド | アルツハイマー病の治療に有用な大環状分子 |
US20050065178A1 (en) * | 2003-09-19 | 2005-03-24 | Anwer Basha | Substituted diazabicycloakane derivatives |
JP2007506723A (ja) * | 2003-09-26 | 2007-03-22 | アストラゼネカ・アクチエボラーグ | 非アミド性ノナン |
US8314119B2 (en) * | 2006-11-06 | 2012-11-20 | Abbvie Inc. | Azaadamantane derivatives and methods of use |
TW200840569A (en) * | 2007-03-13 | 2008-10-16 | Targacept Inc | Sub-type selective amides of diazabicycloalkanes |
US8163914B2 (en) | 2007-03-23 | 2012-04-24 | Abbott Laboratories | Acetamide and carboxamide derivatives of azaadamantane and methods of use thereof |
JP5394940B2 (ja) | 2007-03-23 | 2014-01-22 | アッヴィ・インコーポレイテッド | アミノメチルアザアダマンタン誘導体およびα7−神経ニコチン性アセチルコリン受容体(NNR類)の選択的調節剤としてのそれの使用 |
CA2679870A1 (en) * | 2007-03-23 | 2008-10-02 | Abbott Laboratories | Azaadamantane ester and carbamate derivatives and methods of use thereof |
DK2507225T3 (en) * | 2009-09-14 | 2016-07-04 | Suven Life Sciences Ltd | L-DIHYDRO-2-OXOQUINOLIN COMPOUNDS AS 5-HT4 RECEPTOR LIGANDS |
-
2010
- 2010-06-18 RU RU2012101784/04A patent/RU2549551C2/ru not_active IP Right Cessation
- 2010-06-18 SG SG2011094141A patent/SG176921A1/en unknown
- 2010-06-18 CN CN2010800368013A patent/CN102459268A/zh active Pending
- 2010-06-18 WO PCT/CN2010/000889 patent/WO2010145208A1/en active Application Filing
- 2010-06-18 AU AU2010262643A patent/AU2010262643B2/en not_active Ceased
- 2010-06-18 PE PE2011002111A patent/PE20121066A1/es not_active Application Discontinuation
- 2010-06-18 JP JP2012515322A patent/JP2012530084A/ja not_active Ceased
- 2010-06-18 RU RU2015110025/04A patent/RU2015110025A/ru not_active Application Discontinuation
- 2010-06-18 CA CA2765466A patent/CA2765466A1/en not_active Abandoned
- 2010-06-18 KR KR1020127001339A patent/KR20120044978A/ko not_active Application Discontinuation
- 2010-06-18 BR BRPI1015043A patent/BRPI1015043A2/pt not_active IP Right Cessation
- 2010-06-18 EP EP10788604.6A patent/EP2443122B1/en not_active Not-in-force
- 2010-06-18 MX MX2011014019A patent/MX2011014019A/es active IP Right Grant
- 2010-06-18 US US12/818,764 patent/US8846661B2/en not_active Expired - Fee Related
- 2010-06-18 NZ NZ597511A patent/NZ597511A/en not_active IP Right Cessation
-
2011
- 2011-12-08 IL IL216883A patent/IL216883A/en not_active IP Right Cessation
-
2015
- 2015-01-21 IL IL236830A patent/IL236830A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2012530084A (ja) | 2012-11-29 |
US8846661B2 (en) | 2014-09-30 |
RU2012101784A (ru) | 2013-07-27 |
IL216883A0 (en) | 2012-02-29 |
AU2010262643B2 (en) | 2015-02-19 |
CA2765466A1 (en) | 2010-12-23 |
IL236830A0 (en) | 2015-03-31 |
CN102459268A (zh) | 2012-05-16 |
NZ597511A (en) | 2014-01-31 |
SG176921A1 (en) | 2012-01-30 |
RU2549551C2 (ru) | 2015-04-27 |
EP2443122A1 (en) | 2012-04-25 |
EP2443122B1 (en) | 2014-03-05 |
PE20121066A1 (es) | 2012-09-13 |
KR20120044978A (ko) | 2012-05-08 |
AU2010262643A1 (en) | 2012-02-02 |
US20100324027A1 (en) | 2010-12-23 |
IL216883A (en) | 2015-02-26 |
BRPI1015043A2 (pt) | 2019-07-09 |
RU2015110025A (ru) | 2015-08-20 |
WO2010145208A1 (en) | 2010-12-23 |
EP2443122A4 (en) | 2012-12-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
GB | Transfer or rights |
Owner name: ABBVIE INC. |
|
FG | Grant or registration |