MX362819B - Uso de agonistas del receptor nicotinico de acetilcolina alfa 7 para el tratamiento de la narcolepsia. - Google Patents
Uso de agonistas del receptor nicotinico de acetilcolina alfa 7 para el tratamiento de la narcolepsia.Info
- Publication number
- MX362819B MX362819B MX2015009154A MX2015009154A MX362819B MX 362819 B MX362819 B MX 362819B MX 2015009154 A MX2015009154 A MX 2015009154A MX 2015009154 A MX2015009154 A MX 2015009154A MX 362819 B MX362819 B MX 362819B
- Authority
- MX
- Mexico
- Prior art keywords
- narcolepsy
- treatment
- receptor agonists
- alpha
- nicotinic receptor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, ***e
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Emergency Medicine (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyridine Compounds (AREA)
Abstract
La invención se refiere al uso de ciertos agonistas del receptor nicotínico de acetilcolina alfa 7 para uso en el tratamiento, mejora, prevención o retraso del avance de la narcolepsia, la somnolencia excesiva durante el día, la perturbación del sueño nocturno y/o la cataplexia.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IB2013/050368 WO2014111751A1 (en) | 2013-01-15 | 2013-01-15 | Use of alpha 7 nicotinic receptor agonists for the treatment of narcolepsy |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2015009154A MX2015009154A (es) | 2016-03-04 |
MX362819B true MX362819B (es) | 2019-02-18 |
Family
ID=47747729
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015009154A MX362819B (es) | 2013-01-15 | 2013-01-15 | Uso de agonistas del receptor nicotinico de acetilcolina alfa 7 para el tratamiento de la narcolepsia. |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP2945626B1 (es) |
JP (1) | JP6137336B2 (es) |
KR (1) | KR101879921B1 (es) |
CN (1) | CN105263492B (es) |
BR (1) | BR112015016994A8 (es) |
CA (1) | CA2898043C (es) |
ES (1) | ES2701083T3 (es) |
MX (1) | MX362819B (es) |
WO (1) | WO2014111751A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019028440A1 (en) * | 2017-08-04 | 2019-02-07 | Skyhawk Therapeutics, Inc. | METHODS AND COMPOSITIONS FOR MODULATING SPLICING |
WO2020163405A1 (en) | 2019-02-05 | 2020-08-13 | Skyhawk Therapeutics, Inc. | Methods and compositions for modulating splicing |
CN113677344A (zh) | 2019-02-06 | 2021-11-19 | 斯基霍克疗法公司 | 用于调节剪接的方法和组合物 |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6953855B2 (en) | 1998-12-11 | 2005-10-11 | Targacept, Inc. | 3-substituted-2(arylalkyl)-1-azabicycloalkanes and methods of use thereof |
GB0010955D0 (en) | 2000-05-05 | 2000-06-28 | Novartis Ag | Organic compounds |
GB0128996D0 (en) | 2001-12-04 | 2002-01-23 | Novartis Ag | Organic compounds |
DE10164139A1 (de) | 2001-12-27 | 2003-07-10 | Bayer Ag | 2-Heteroarylcarbonsäureamide |
SE0201943D0 (sv) | 2002-06-20 | 2002-06-20 | Astrazeneca Ab | New use |
WO2004016608A1 (en) * | 2002-08-14 | 2004-02-26 | Neurosearch A/S | Novel quinuclidine derivatives and their use |
GB0220581D0 (en) | 2002-09-04 | 2002-10-09 | Novartis Ag | Organic Compound |
EE05516B1 (et) * | 2002-09-25 | 2012-02-15 | Memory@Pharmaceuticals@Corporation | Indasoolid bensotiasoolid ja bensoisotiasoolid nende valmistamine ning kasutamine |
EP1677790A1 (en) | 2003-10-31 | 2006-07-12 | AstraZeneca AB | Alkynes ii |
WO2005044265A1 (en) | 2003-10-31 | 2005-05-19 | Astrazeneca Ab | Alkynes iii |
CN1870999A (zh) | 2003-10-31 | 2006-11-29 | 阿斯利康(瑞典)有限公司 | 炔烃ⅰ |
US20050245531A1 (en) | 2003-12-22 | 2005-11-03 | Abbott Laboratories | Fused bicycloheterocycle substituted quinuclidine derivatives |
EP1715867A4 (en) | 2004-02-12 | 2009-04-15 | Merck & Co Inc | BIPYRIDYL AMIDES AS MODULATORS OF GLUTAMATE METABOTROPIC REPEATER-5 |
GB0412019D0 (en) | 2004-05-28 | 2004-06-30 | Novartis Ag | Organic compounds |
AR049401A1 (es) * | 2004-06-18 | 2006-07-26 | Novartis Ag | Aza-biciclononanos |
GB0415746D0 (en) * | 2004-07-14 | 2004-08-18 | Novartis Ag | Organic compounds |
JP2008538417A (ja) | 2005-04-08 | 2008-10-23 | エクステラス インコーポレイテッド | 多重チャンネル波長分散補償器 |
GB0508319D0 (en) | 2005-04-25 | 2005-06-01 | Novartis Ag | Organic compounds |
GB0521508D0 (en) * | 2005-10-21 | 2005-11-30 | Novartis Ag | Organic compounds |
GB0525673D0 (en) * | 2005-12-16 | 2006-01-25 | Novartis Ag | Organic compounds |
GB0525672D0 (en) | 2005-12-16 | 2006-01-25 | Novartis Ag | Organic compounds |
JP2009519986A (ja) | 2005-12-20 | 2009-05-21 | ノバルティス アクチエンゲゼルシャフト | 代謝型グルタミン酸受容体のモジュレーターとしてのニコチン酸誘導体 |
TW200813067A (en) | 2006-05-17 | 2008-03-16 | Astrazeneca Ab | Nicotinic acetylcholine receptor ligands |
CN102516241B (zh) | 2006-05-19 | 2015-07-29 | 艾伯维巴哈马有限公司 | Cns活性的稠合的双环杂环取代的氮杂双环烷烃衍生物 |
US8314119B2 (en) | 2006-11-06 | 2012-11-20 | Abbvie Inc. | Azaadamantane derivatives and methods of use |
SA08290475B1 (ar) * | 2007-08-02 | 2013-06-22 | Targacept Inc | (2s، 3r)-n-(2-((3-بيردينيل)ميثيل)-1-آزا بيسيكلو[2، 2، 2]أوكت-3-يل)بنزو فيوران-2-كربوكساميد، وصور أملاحه الجديدة وطرق استخدامه |
WO2009066107A1 (en) | 2007-11-21 | 2009-05-28 | Astrazeneca Ab | Use of a nicotinic receptor agonist |
BRPI0920187A2 (pt) | 2008-10-13 | 2019-08-27 | Hoffmann La Roche | método sem diazônio para fabricar um indazol intermediário na síntese de amidas bicíclicas do ácido 5-(triflúor-metóxi)-1h-3-indazol-carboxílico |
EP2364150A1 (en) | 2008-11-11 | 2011-09-14 | Targacept Inc. | Treatment with alpha 7-selective ligands |
TW201031664A (en) * | 2009-01-26 | 2010-09-01 | Targacept Inc | Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide |
JP2012533601A (ja) * | 2009-07-23 | 2012-12-27 | ノバルティス アーゲー | 運動失調症の処置または予防のための、アザビシクロアルキル誘導体またはピロリジン−2−オン誘導体の使用 |
-
2013
- 2013-01-15 EP EP13705591.9A patent/EP2945626B1/en active Active
- 2013-01-15 KR KR1020157021932A patent/KR101879921B1/ko active IP Right Grant
- 2013-01-15 JP JP2015552147A patent/JP6137336B2/ja active Active
- 2013-01-15 MX MX2015009154A patent/MX362819B/es active IP Right Grant
- 2013-01-15 CA CA2898043A patent/CA2898043C/en active Active
- 2013-01-15 CN CN201380074626.0A patent/CN105263492B/zh active Active
- 2013-01-15 WO PCT/IB2013/050368 patent/WO2014111751A1/en active Application Filing
- 2013-01-15 ES ES13705591T patent/ES2701083T3/es active Active
- 2013-01-15 BR BR112015016994A patent/BR112015016994A8/pt not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
BR112015016994A8 (pt) | 2018-01-23 |
JP6137336B2 (ja) | 2017-05-31 |
CN105263492B (zh) | 2018-04-10 |
CN105263492A (zh) | 2016-01-20 |
WO2014111751A1 (en) | 2014-07-24 |
CA2898043C (en) | 2019-08-06 |
EP2945626A1 (en) | 2015-11-25 |
KR101879921B1 (ko) | 2018-07-18 |
MX2015009154A (es) | 2016-03-04 |
JP2016504407A (ja) | 2016-02-12 |
KR20150104632A (ko) | 2015-09-15 |
BR112015016994A2 (pt) | 2017-07-11 |
ES2701083T3 (es) | 2019-02-20 |
EP2945626B1 (en) | 2018-09-12 |
CA2898043A1 (en) | 2014-07-24 |
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Legal Events
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FG | Grant or registration |