MX2008001213A - Formulacion farmaceutica de derivados nitrooxi de farmacos anti-inflamatorios no esteroidales. - Google Patents

Formulacion farmaceutica de derivados nitrooxi de farmacos anti-inflamatorios no esteroidales.

Info

Publication number
MX2008001213A
MX2008001213A MX2008001213A MX2008001213A MX2008001213A MX 2008001213 A MX2008001213 A MX 2008001213A MX 2008001213 A MX2008001213 A MX 2008001213A MX 2008001213 A MX2008001213 A MX 2008001213A MX 2008001213 A MX2008001213 A MX 2008001213A
Authority
MX
Mexico
Prior art keywords
sub
pharmaceutical formulation
nitrooxyderivatives
nsaids
formula
Prior art date
Application number
MX2008001213A
Other languages
English (en)
Inventor
Christina Holmberg
Ulla Gasslander
Original Assignee
Nicox Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nicox Sa filed Critical Nicox Sa
Publication of MX2008001213A publication Critical patent/MX2008001213A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invencion se refiere a una formulacion farmaceutica que comprende: a) uno o mas de los NSAID de liberacion de NO de formula (I); (ver formula) b) uno o mas agentes tensioactivos; c) un compuesto depurador de carbonilo seleccionado de formas de acido libre, sales, derivados de ester de acido carboxilico de un compuesto de formula (II): (H2N-(CH2)m-(C6H4)-COOH (II)) en donde m = 0-10, y d) opcionalmente un aceite o grasa semi-solida y/o un alcohol de cadena corta.
MX2008001213A 2005-07-26 2006-06-29 Formulacion farmaceutica de derivados nitrooxi de farmacos anti-inflamatorios no esteroidales. MX2008001213A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05106854 2005-07-26
PCT/EP2006/063672 WO2007012539A2 (en) 2005-07-26 2006-06-29 Pharmaceutical formulation of nitrooxyderivatives of nsaids

Publications (1)

Publication Number Publication Date
MX2008001213A true MX2008001213A (es) 2008-03-24

Family

ID=37670077

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2008001213A MX2008001213A (es) 2005-07-26 2006-06-29 Formulacion farmaceutica de derivados nitrooxi de farmacos anti-inflamatorios no esteroidales.

Country Status (25)

Country Link
US (1) US8691869B2 (es)
EP (1) EP1906938B1 (es)
JP (1) JP5238499B2 (es)
KR (1) KR101342910B1 (es)
CN (1) CN101227896B (es)
AR (1) AR055094A1 (es)
AT (1) ATE485033T1 (es)
AU (1) AU2006274098B2 (es)
CA (1) CA2616508C (es)
CY (1) CY1112023T1 (es)
DE (1) DE602006017701D1 (es)
DK (1) DK1906938T3 (es)
ES (1) ES2354278T3 (es)
HK (1) HK1120414A1 (es)
HR (1) HRP20110025T1 (es)
IL (1) IL188253A0 (es)
MX (1) MX2008001213A (es)
NO (1) NO20080983L (es)
NZ (1) NZ564589A (es)
PL (1) PL1906938T3 (es)
PT (1) PT1906938E (es)
RU (1) RU2406482C2 (es)
SI (1) SI1906938T1 (es)
WO (1) WO2007012539A2 (es)
ZA (1) ZA200801009B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011209757A (ja) * 2011-07-06 2011-10-20 Rohto Pharmaceutical Co Ltd コンタクトレンズケア方法及び組成物
US9688607B2 (en) * 2011-08-15 2017-06-27 Research Foundation Of The City University Of New York No- and H2S-releasing compounds
WO2013130625A1 (en) * 2012-02-27 2013-09-06 Basil Rigas Phospho-ester derivatives and uses thereof
RU2657803C1 (ru) * 2017-03-21 2018-06-15 федеральное государственное бюджетное образовательное учреждение высшего образования "Алтайский государственный университет" Средство, обладающее противовоспалительным и анальгезирующим действием

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1925697A (en) * 1996-03-12 1997-10-01 Novartis Ag Filled gelatin capsules having a reduced degree of cross-linking
TWI243672B (en) * 1999-06-01 2005-11-21 Astrazeneca Ab New use of compounds as antibacterial agents
SE0000774D0 (sv) * 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
SE0000773D0 (sv) * 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
ES2524000T3 (es) 2002-06-05 2014-12-03 Teva Czech Industries S.R.O. Reducción de la reticulación de la gelatina
BR0313150A (pt) * 2002-07-31 2005-06-28 Pharmacia Corp Cápsulas de gelatina que exibem ligação reticulada reduzida

Also Published As

Publication number Publication date
AU2006274098B2 (en) 2012-02-09
AR055094A1 (es) 2007-08-08
JP5238499B2 (ja) 2013-07-17
CY1112023T1 (el) 2015-11-04
EP1906938A2 (en) 2008-04-09
ES2354278T3 (es) 2011-03-11
IL188253A0 (en) 2008-04-13
PL1906938T3 (pl) 2011-05-31
KR101342910B1 (ko) 2013-12-19
RU2008104505A (ru) 2009-09-10
CA2616508C (en) 2015-02-24
ZA200801009B (en) 2008-11-26
CN101227896B (zh) 2013-02-06
DK1906938T3 (da) 2011-02-07
RU2406482C2 (ru) 2010-12-20
JP2009502850A (ja) 2009-01-29
HRP20110025T1 (hr) 2011-03-31
AU2006274098A1 (en) 2007-02-01
US20090203759A1 (en) 2009-08-13
PT1906938E (pt) 2011-01-17
EP1906938B1 (en) 2010-10-20
DE602006017701D1 (de) 2010-12-02
SI1906938T1 (sl) 2011-02-28
HK1120414A1 (en) 2009-04-03
NZ564589A (en) 2010-01-29
WO2007012539A2 (en) 2007-02-01
CA2616508A1 (en) 2007-02-01
WO2007012539A3 (en) 2007-04-19
CN101227896A (zh) 2008-07-23
ATE485033T1 (de) 2010-11-15
KR20080028412A (ko) 2008-03-31
NO20080983L (no) 2008-02-25
US8691869B2 (en) 2014-04-08

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