MA31016B1 - Composes de diazepan substitues comme antagonistes des recepteurs de l'orexine. - Google Patents

Composes de diazepan substitues comme antagonistes des recepteurs de l'orexine.

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Publication number
MA31016B1
MA31016B1 MA32022A MA32022A MA31016B1 MA 31016 B1 MA31016 B1 MA 31016B1 MA 32022 A MA32022 A MA 32022A MA 32022 A MA32022 A MA 32022A MA 31016 B1 MA31016 B1 MA 31016B1
Authority
MA
Morocco
Prior art keywords
antagonists
compounds substituted
orexin receptors
compounds
receptors
Prior art date
Application number
MA32022A
Other languages
English (en)
Inventor
Jeffrey M Bergman
Michael J Breslin
Paul J Coleman
Christopher D Cox
Swati P Mercer
Anthony J Roecker
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39284173&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA31016(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of MA31016B1 publication Critical patent/MA31016B1/fr

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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
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Abstract

LA PRÉSENTE INVENTION CONCERNE DES COMPOSÉS DE DIAZÉPANE SUBSTITUÉS QUI SONT DES ANTAGONISTES DES RÉCEPTEURS DE L'OREXINE ET SE RÉVÈLENT UTILES POUR LE TRAITEMENT OU LA PRÉVENTION DE TROUBLES ET DE MALADIES NEUROLOGIQUES ET PSYCHIATRIQUES DANS LESQUELS LES RÉCEPTEURS DE L'OREXINE SONT IMPLIQUÉS. L'INVENTION CONCERNE ÉGALEMENT DES COMPOSITIONS PHARMACEUTIQUES RENFERMANT CES COMPOSÉS AINSI QUE L'UTILISATION DE CES COMPOSÉS ET DE CES COMPOSITIONS DANS LA PRÉVENTION OU LE TRAITEMENT DE MALADIES DANS LESQUELLES LES RÉCEPTEURS DE L'OREXINE SONT IMPLIQUÉS.
MA32022A 2006-12-01 2009-06-22 Composes de diazepan substitues comme antagonistes des recepteurs de l'orexine. MA31016B1 (fr)

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