KR900701262A - 췌장염 등에 대한 치료제 - Google Patents

췌장염 등에 대한 치료제

Info

Publication number
KR900701262A
KR900701262A KR1019900700238A KR900700238A KR900701262A KR 900701262 A KR900701262 A KR 900701262A KR 1019900700238 A KR1019900700238 A KR 1019900700238A KR 900700238 A KR900700238 A KR 900700238A KR 900701262 A KR900701262 A KR 900701262A
Authority
KR
South Korea
Prior art keywords
group
optionally substituted
alkyl
nitro
pancreatitis
Prior art date
Application number
KR1019900700238A
Other languages
English (en)
Inventor
야스히로 가쯔우라
노리오 오노
모리히꼬 야마다
요시오 기무라
아끼꼬 오꾸노미야
게이꼬 와나까
Original Assignee
오까모도 쇼오스께
무라다 하지메
쇼오와 덴꾜오 가부시끼가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 오까모도 쇼오스께, 무라다 하지메, 쇼오와 덴꾜오 가부시끼가이샤 filed Critical 오까모도 쇼오스께
Publication of KR900701262A publication Critical patent/KR900701262A/ko

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim

Abstract

내용 없음

Description

췌장염 등에 대한 치료제
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (1)

  1. 일반식 :
    으로 표현되는 화합물 또는 약학적으로 허용되는 이것의 염을 유효성분으로서 함유하고, 식 중에서 A는나타내고, X1및 X2중의 한 가지는 수로를 나타내고 다른 한 가지는 수소, 니트로기. 페녹시기 (니트로기 또는 할로겐으로 선택적 치환되었다), 벤질옥시기, 피콜일옥시기 또는 피리딜옥시기 (니트로기에 의해 선택적 치환되었다)를 나타내며, Y는 C1-C6알킬기, 페닐기 (C1-C4알킬 카르보닐기, 페닐카르 보닐기, 카르보닐기에 의해 선택적 치환되었거나, 또는 카르복실기 또는 C1-C4알콕시 카르보닐기에 의해 선택적 치환된 C1-C4알킬기에 의해 선택적 치환되었다), 피리딜기 (할로겐에 의해 선택적 치환되었다), 또는 피리미딜기인 것을 특징으로 하는, 췌장염 등에 대한 제약 재조물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019900700238A 1988-06-06 1989-06-06 췌장염 등에 대한 치료제 KR900701262A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP63-139135 1988-06-06
JP13913588 1988-06-06
PCT/JP1989/000567 WO1989011852A1 (en) 1988-06-06 1989-06-06 Agent for treating pancreatitis or the like

Publications (1)

Publication Number Publication Date
KR900701262A true KR900701262A (ko) 1990-12-01

Family

ID=15238352

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019900700238A KR900701262A (ko) 1988-06-06 1989-06-06 췌장염 등에 대한 치료제

Country Status (4)

Country Link
EP (1) EP0369035A4 (ko)
KR (1) KR900701262A (ko)
AU (1) AU3737289A (ko)
WO (1) WO1989011852A1 (ko)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006076706A1 (en) 2005-01-14 2006-07-20 Millennium Pharmaceuticals, Inc. Cinnamide and hydrocinnamide derivatives with raf-kinase inhibitory activity
HUE031004T2 (en) 2010-12-27 2017-06-28 Gemphire Therapeutics Inc Gemcock and its derivatives for the treatment of pancreatitis
US20160244437A1 (en) 2013-09-26 2016-08-25 Bayer Pharma Aktiengesellschaft Substituted phenylalanine derivatives
US20160237044A1 (en) 2013-09-26 2016-08-18 Bayer Pharma Aktiengesellschaft Substituted phenylalanine derivatives
UY35747A (es) 2013-09-26 2015-04-30 Bayer Pharma AG Derivados sustituidos de fenilalanina
WO2016146605A1 (de) 2015-03-19 2016-09-22 Bayer Pharma Aktiengesellschaft Substituierte phenylalanin-derivate
WO2016146604A1 (de) 2015-03-19 2016-09-22 Bayer Pharma Aktiengesellschaft 7-{4-[(2s)-2-({[trans-4-(aminomethyl)cyclohexyl]carbonyl}amino)-3-(phenylamino)-3-oxopropyl]phenyl}-6-methyl-4-oxo-1,4-dihydrochinolin-3-carbonsäure-derivate als faktor xia inhibitoren zur behandlung von fibrinolytischen erkrankungen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS611651A (ja) * 1984-06-12 1986-01-07 Toyama Chem Co Ltd Ｎ−アシル酸性アミノ酸ジアミド類およびその製造法並びにそれらを含有する抗潰瘍剤
EP0183271B1 (en) * 1984-11-30 1990-05-16 Shosuke Okamoto Lysin derivative and proteinase inhibitor
JPS626681A (ja) * 1985-07-02 1987-01-13 Showa Denko Kk 抗蛋白分解酵素阻害剤
JPH0753705B2 (ja) * 1985-09-27 1995-06-07 三菱化学株式会社 フエニルアラニン誘導体および蛋白分解酵素阻害剤
JPS6272656A (ja) * 1985-09-27 1987-04-03 Showa Denko Kk リジン誘導体及び蛋白分解酵素阻害剤
JPS63239256A (ja) * 1987-03-27 1988-10-05 Showa Denko Kk フエニルアラニン誘導体および蛋白分解酵素阻害剤
EP0284632A1 (en) * 1987-03-30 1988-10-05 Shosuke Okamoto Phenylalanine derivative and proteinase inhibitor

Also Published As

Publication number Publication date
EP0369035A4 (en) 1991-07-17
EP0369035A1 (en) 1990-05-23
WO1989011852A1 (en) 1989-12-14
AU3737289A (en) 1990-01-05

Similar Documents

Publication Publication Date Title
FI925100A (fi) Substituerade bifenylpyridoner
DE3686483D1 (de) Arzneimittel.
KR970021076A (ko) 약제학적 활성 성분으로서 치환된 2,4-이미다졸리딘디온 화합물
ES8207169A1 (es) Un procedimiento para la preparacion de nuevos derivados de piperazinilquinazolina y de homopiperazinilquinazolina hi- pertensora con acticidad.
KR900003163A (ko) 시클로헥산 유도체
FR2681784B1 (fr) Composition dermatologique et/ou cosmetologique contenant des retinouides et utilisation de nouveaux retinouides.
DE68902301T2 (de) Diarylverbindungen als antiatherosklerotische mittel.
KR850002377A (ko) 살충제 조성물
KR900701262A (ko) 췌장염 등에 대한 치료제
KR900701795A (ko) 티에노시클로 헵타피리다진 화합물과 그것의 의약용도
ATE34661T1 (de) Verbindungen zur verminderung des lipidspiegels.
KR920703050A (ko) 골형성 촉진제
ES2096099T3 (es) Perhidro-1h-pirido(1,2,a)pirazinas 2-sustituidas neurolepticas.
KR890001540A (ko) 심부전증 치료제
KR900016156A (ko) 퀴녹살린 유도체 및 궤양치료제
KR890001543A (ko) 당뇨병 치료제
KR920019349A (ko) 불안을 치료하기 위한 r(+)-3-아미노-1-하이드록시-피롤리딘-2-온의 용도
KR900016144A (ko) 4-이미다졸린 유도체
KR900014360A (ko) 피리딘카복실산 아미드 유도체 및 이를 함유하는 약학 조성물
KR890009270A (ko) 식물 보호용 살균제
KR880012518A (ko) 나프탈-아세트산 유도체를 함유하는 진통 및 소염제약 조성물
KR890002077A (ko) 하이드로퀴논일페닐 부티르산 아미드 유도체
KR900012884A (ko) (+)1-[(3,4,5-트리메톡시)-벤질옥시메틸]-1-페닐-N,N-디메틸-n-프로필아민, 그의 제조방법 및 치료학적 용도
KR920002531A (ko) 스페르구알린 관련 신규화합물 및 그 제조방법
KR940703656A (ko) 에이즈 바이러스 감염 저해용 조성물

Legal Events

Date Code Title Description
WITN Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid