KR900701795A - 티에노시클로 헵타피리다진 화합물과 그것의 의약용도 - Google Patents
티에노시클로 헵타피리다진 화합물과 그것의 의약용도Info
- Publication number
- KR900701795A KR900701795A KR1019900701038A KR900701038A KR900701795A KR 900701795 A KR900701795 A KR 900701795A KR 1019900701038 A KR1019900701038 A KR 1019900701038A KR 900701038 A KR900701038 A KR 900701038A KR 900701795 A KR900701795 A KR 900701795A
- Authority
- KR
- South Korea
- Prior art keywords
- thieno
- cyclohepta
- pyridazin
- tetrahydro
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (5)
- 하기 일반식의 티에노시클로헵타 피리다진 화합물.상기식에서, R은 수소, 할로겐 또는 C1-4아킬이고, Ar은 아릴, 헤테로아릴, 또는 치환기로 할로겐, C1-4알킬, C1-4알콕시, 니트로, 아미노, 히드록시, 트리플루오로메틸 및/또는 C2-5알카노일-아미노를 적어도 하나 갖는 아릴 또는 헤테로 아릴이며, 6a위치와 7위치 간의 결합 ………은 단일 결합 또는 이중결합이다.
- 제1항에 있어서, 9-(4-클로로페닐)-2-메틸 5,6,6a,7-테트라히드로 -4H-티에노〔2,3,-f〕시클로헵타〔1,2-c〕피리다진-8(9H)-온, 9-페닐-2-메틸 5,6,6a,7-테트라히드로-4H-티에노〔2,3-f〕시클로헵타〔1,2-c〕피리다진-8(9H)-온, 9-(4-메틸페)-2-메틸 5,6,6a,7-테트라히드로-4H-티에노〔2,3-f〕 시클로헵타 〔1,2-c〕 피리다진-8(9H)-온, 9-(4-메톡시 페닐)-2-메틸-5,6,6a,7-테드라히드로-4H-티에노〔2,3-f〕 시클로헵타 〔1,2-c〕 피리다진-8(9H)-온, 9-(4-클로로 페닐)-5,6-디히드로-2-메틸-4H-티에노〔2,3-f〕 시클로헵타 〔1,2-c〕 피리다진-8(9H)-온, 9-(4-클로로 페닐)-5,6,6a,7-테트라히드로-4H-티에노〔2,3-f〕 시클로헵타 〔1,2-c〕 피리다진-8(9H)-온, 9-(6-클로로-2-피리딜)-5,6,6a,7-테트라히드로-4H-티에노〔2,3-f〕 시클로헵타 〔1,2-c〕 피리다진-8(9H)-온, 9-(4-메틸페닐)-5,6,6a,7-테트라히드로-4H-티에노〔2,3-f〕 시클로헵타 〔1,2-c〕 피리다진-8(9H)-온, 9-(4-메톡시페닐)-5,6,6a,7-테트라히드로-4H-티에노〔2,3-f〕 시클로헵타 〔1,2-c〕 피리다진-8(9H)-온, 2-브로모-9-(4-클로로페닐)-5,6,6a,7-테트라히드로-4H-티에노〔2,3-f〕 시클로헵타 〔1,2-c〕 피리다진-8(9H)-온, 2-브로모-9-(4-클로로페닐)-5,6,6a,7-테트라히드로-4H-티에노〔2,3-f〕 시클로헵타 〔1,2-c〕피리다진-8(9H)-온, 및 2-브로모-9-(4-클로로페닐)-5,6-디히드로-4H-티에노〔2,3-f〕 시클로헵타〔1,2-c〕 피리다진-8(9H)-온, 등의 그룹중에서 선택된 화합물.
- 제1항 또는 제2항의 화합물과 의약용 첨가제를 함유한 의약 조성물.
- 제1항 또는 제2항의 화합물을 유효성분으로 함유한 항 불안제.
- 제1항 또는 제2항의 화합물을 유효성분으로 함유한 건망증 치료제, 뇌기능 활성제 또는 항치매제.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP237600 | 1988-09-21 | ||
JP23760088 | 1988-09-21 | ||
JP237600/88 | 1988-09-21 | ||
PCT/JP1989/000956 WO1990003380A1 (en) | 1988-09-21 | 1989-09-20 | Thienocycloheptapyridazine compounds and medicinal uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
KR900701795A true KR900701795A (ko) | 1990-12-04 |
KR920007437B1 KR920007437B1 (ko) | 1992-09-01 |
Family
ID=17017723
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019900701038A KR920007437B1 (ko) | 1988-09-21 | 1989-09-20 | 티에노시클로 헵타 피리다진 화합물과 그것의 의약용도 |
Country Status (4)
Country | Link |
---|---|
US (1) | US5153194A (ko) |
EP (1) | EP0394471A4 (ko) |
KR (1) | KR920007437B1 (ko) |
WO (1) | WO1990003380A1 (ko) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2028496A1 (en) * | 1989-10-31 | 1991-05-01 | Tohru Nakao | Thiophene compounds and their pharmaceutical uses |
US5597918A (en) * | 1991-08-27 | 1997-01-28 | Yoshitomi Pharmaceutical Industries, Ltd. | Fused pyridazine compound |
US5840737A (en) | 1996-01-04 | 1998-11-24 | The Curators Of The University Of Missouri | Omeprazole solution and method for using same |
US6489346B1 (en) | 1996-01-04 | 2002-12-03 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US6645988B2 (en) | 1996-01-04 | 2003-11-11 | Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and method of using same |
US6699885B2 (en) | 1996-01-04 | 2004-03-02 | The Curators Of The University Of Missouri | Substituted benzimidazole dosage forms and methods of using same |
US8993599B2 (en) | 2003-07-18 | 2015-03-31 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US8815916B2 (en) | 2004-05-25 | 2014-08-26 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
US8906940B2 (en) | 2004-05-25 | 2014-12-09 | Santarus, Inc. | Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3631174A (en) * | 1970-01-06 | 1971-12-28 | American Cyanamid Co | 4 5-heterocyclic substituted-6 7-dihydrobenzothiophenes |
US3816437A (en) * | 1972-12-22 | 1974-06-11 | Sandoz Ag | Thieno(2,3-g)indazoles |
US4602019A (en) * | 1983-04-22 | 1986-07-22 | Warner-Lambert Company | Indeno[1,2-c]pyridazin-3-one derivatives useful as cardiotonic and antihypertensive agents |
GB2164643B (en) * | 1984-07-27 | 1988-11-02 | Boehringer Biochemia Srl | Tricyclic dihydropyridazinones and pharmaceutical compositions containing them |
JPH06763B2 (ja) * | 1984-08-28 | 1994-01-05 | 吉富製薬株式会社 | ベンゾ〔h〕シンノリン誘導体 |
AU578496B2 (en) * | 1984-11-01 | 1988-10-27 | Smith Kline & French Laboratories Limited | Tricyclic heterocyclic compounds |
JPH0633277B2 (ja) * | 1986-01-10 | 1994-05-02 | 吉富製薬株式会社 | ベンゾチオピラノ〔4,3−c〕ピリダジン化合物 |
DE3867086D1 (de) * | 1987-03-02 | 1992-02-06 | Yoshitomi Pharmaceutical | Benzothiepino(5,4-c)pyridazin-verbindungen und ihre pharmazeutischen wirkungen. |
JP2615785B2 (ja) * | 1987-03-25 | 1997-06-04 | 吉富製薬株式会社 | チエノシンノリン化合物 |
WO1988007533A1 (en) * | 1987-03-25 | 1988-10-06 | Yoshitomi Pharmaceutical Industries, Ltd. | Thienocinnoline compounds and their medicinal application |
US5032216A (en) * | 1989-10-20 | 1991-07-16 | E. I. Du Pont De Nemours And Company | Non-photographic method for patterning organic polymer films |
-
1989
- 1989-09-20 EP EP19890910671 patent/EP0394471A4/en not_active Withdrawn
- 1989-09-20 US US07/490,609 patent/US5153194A/en not_active Expired - Fee Related
- 1989-09-20 KR KR1019900701038A patent/KR920007437B1/ko not_active IP Right Cessation
- 1989-09-20 WO PCT/JP1989/000956 patent/WO1990003380A1/ja not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR920007437B1 (ko) | 1992-09-01 |
WO1990003380A1 (en) | 1990-04-05 |
US5153194A (en) | 1992-10-06 |
EP0394471A1 (en) | 1990-10-31 |
EP0394471A4 (en) | 1991-12-18 |
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GRNT | Written decision to grant | ||
LAPS | Lapse due to unpaid annual fee |