US1032805A
(en)
|
1903-03-11 |
1912-07-16 |
Miller O A Treeing Machine Co |
Shoe-form.
|
US4851423A
(en)
|
1986-12-10 |
1989-07-25 |
Schering Corporation |
Pharmaceutically active compounds
|
MX9200299A
(es)
|
1991-02-07 |
1992-12-01 |
Roussel Uclaf |
Nuevos derivados biciclicos nitrogenados, su procedimiento de preparacion los nuevos compuestos intermedios obtenidos su aplicacion como medicamentos y las composiciones farmaceuticas que los contienen.
|
EP0934307B1
(en)
|
1996-06-19 |
2011-04-27 |
Aventis Pharma Limited |
Substituted azabicylic compounds and their use as inhibitors of the production of tnf and cyclic amp phosphodiesterase
|
JP2001519387A
(ja)
|
1997-09-29 |
2001-10-23 |
ブリストル−マイヤーズ スクイブ カンパニー |
ファルネシルたんぱく転移酵素のインヒビター
|
US6232320B1
(en)
|
1998-06-04 |
2001-05-15 |
Abbott Laboratories |
Cell adhesion-inhibiting antiinflammatory compounds
|
WO1999062908A2
(en)
|
1998-06-04 |
1999-12-09 |
Abbott Laboratories |
Cell adhesion-inhibiting antinflammatory compounds
|
WO2000075145A1
(en)
|
1999-06-03 |
2000-12-14 |
Abbott Laboratories |
Cell adhesion-inhibiting antiinflammatory compounds
|
EP1202970A1
(en)
|
1999-07-30 |
2002-05-08 |
Vertex Pharmaceuticals Incorporated |
Cyclic amine derivatives for the treatment of neurological diseases
|
WO2001014336A1
(fr)
|
1999-08-20 |
2001-03-01 |
Nippon Kayaku Kabushiki Kaisha |
Derives benzeniques substitues par un cycle aromatique, et leur procede de production
|
AU2001264313A1
(en)
|
2000-06-20 |
2002-01-02 |
Japan Tobacco Inc. |
Pyrazolopyridine compounds and use thereof as drugs
|
GB0021885D0
(en)
|
2000-09-06 |
2000-10-18 |
Fujisawa Pharmaceutical Co |
New use
|
DE10046029A1
(de)
|
2000-09-18 |
2002-03-28 |
Bayer Ag |
Indazole
|
EP1217000A1
(en)
|
2000-12-23 |
2002-06-26 |
Aventis Pharma Deutschland GmbH |
Inhibitors of factor Xa and factor VIIa
|
IL156827A0
(en)
|
2001-02-20 |
2004-02-08 |
Chugai Pharmaceutical Co Ltd |
Azoles as malonyl-coa decarboxylase inhibitors useful as metabolic modulators
|
JP4176477B2
(ja)
|
2001-03-01 |
2008-11-05 |
塩野義製薬株式会社 |
Hivインテグラーゼ阻害活性を有する含窒素芳香族複素環誘導体
|
JP2005507367A
(ja)
|
2001-04-13 |
2005-03-17 |
ベーリンガー インゲルハイム ファーマシューティカルズ インコーポレイテッド |
1,4−二置換ベンゾ縮合化合物
|
US6890915B2
(en)
|
2001-05-25 |
2005-05-10 |
Bristol-Myers Squibb Pharma Company |
Hydantoins and related heterocycles as inhibitors of matrix metalloproteinases and/or TNF-α converting enzyme (TACE)
|
US20030144350A1
(en)
|
2001-07-20 |
2003-07-31 |
Adipogenix, Inc. |
Fat accumulation-modulation compounds
|
US7294624B2
(en)
|
2001-12-20 |
2007-11-13 |
Bristol Myers Squibb Company |
Barbituric acid derivatives as inhibitors of TNF-α converting enzyme (TACE) and/or matrix metalloproteinases
|
US20030236277A1
(en)
*
|
2002-02-14 |
2003-12-25 |
Kadow John F. |
Indole, azaindole and related heterocyclic pyrrolidine derivatives
|
US6995144B2
(en)
|
2002-03-14 |
2006-02-07 |
Eisai Co., Ltd. |
Nitrogen containing heterocyclic compounds and medicines containing the same
|
AU2003235118C1
(en)
|
2002-04-25 |
2010-01-07 |
Ono Pharmaceutical Co., Ltd. |
Diketohydrazine derivative compounds and drugs containing the compounds as the active ingredient
|
WO2004024705A1
(ja)
|
2002-09-10 |
2004-03-25 |
Takeda Pharmaceutical Company Limited |
5員複素環化合物
|
EP1537105A2
(en)
|
2002-09-13 |
2005-06-08 |
Synta Pharmaceuticals Corporation |
Synthesis of indolizines
|
PL376154A1
(en)
|
2002-09-18 |
2005-12-27 |
Ono Pharmaceutical Co, Ltd. |
Triazaspiro[5.5]undecane derivatives and drugs comprising the same as the active ingredient
|
US20060019977A1
(en)
|
2002-10-18 |
2006-01-26 |
Ono Pharmaceutical Co., Ltd. |
Spiroheterocyclic derivative compounds and drugs comprising the compound as the active ingredient
|
EP1581496A4
(en)
|
2002-12-02 |
2008-04-23 |
Gilead Sciences Inc |
2-SUBSTITUTED 3-PROPENAMIDE DERIVATIVES AND PROCESS FOR THEIR PREPARATION
|
US7320989B2
(en)
|
2003-02-28 |
2008-01-22 |
Encysive Pharmaceuticals, Inc. |
Pyridine, pyrimidine, quinoline, quinazoline, and naphthalene urotensin-II receptor antagonists
|
WO2004082606A2
(en)
|
2003-03-13 |
2004-09-30 |
Synta Pharmaceuticals Corp. |
Fused pyrrole compounds
|
EP1479676A1
(en)
|
2003-05-19 |
2004-11-24 |
Aventis Pharma Deutschland GmbH |
Benzimidazole-derivatives as factor xa inhibitors
|
EP1670787B1
(en)
|
2003-09-11 |
2012-05-30 |
iTherX Pharma, Inc. |
Cytokine inhibitors
|
WO2005033072A2
(en)
|
2003-09-30 |
2005-04-14 |
Scios Inc. |
Heterocyclic amides and sulfonamides
|
BRPI0415678A
(pt)
|
2003-10-23 |
2006-12-19 |
Pharmacia Corp |
compostos de pirimidina para o tratamento de inflamação
|
WO2005039506A2
(en)
|
2003-10-24 |
2005-05-06 |
Exelixis, Inc. |
P70s6 kinase modulators and method of use
|
US20050137243A1
(en)
|
2003-12-23 |
2005-06-23 |
Souers Andrew J. |
Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor
|
US7049307B2
(en)
|
2003-12-23 |
2006-05-23 |
Abbott Laboratories |
Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor
|
US7071182B2
(en)
|
2003-12-23 |
2006-07-04 |
Abbott Laboratories |
Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor
|
US20050137187A1
(en)
|
2003-12-23 |
2005-06-23 |
Souers Andrew J. |
Antagonists of melanin concentrating hormone effects on the melanin concentrating hormone receptor
|
CN1922174A
(zh)
*
|
2004-02-20 |
2007-02-28 |
贝林格尔·英格海姆国际有限公司 |
病毒聚合酶抑制剂
|
KR20060129077A
(ko)
|
2004-03-09 |
2006-12-14 |
베링거 인겔하임 파마슈티칼즈, 인코포레이티드 |
만성 염증 질환을 치료하기 위한 사이토킨 생성억제제로서의3-'4-헤테로사이클릴-1,2,3-트리아졸-1-일-n-아릴-벤즈아미드
|
WO2005099824A1
(en)
|
2004-03-30 |
2005-10-27 |
Synta Pharmaceuticals, Corp. |
1-glyoxylamide indolizines for treating lung and ovarian cancer
|
EP1741441A4
(en)
|
2004-04-26 |
2010-03-03 |
Ono Pharmaceutical Co |
BONE-ENHANCING AGENT CHARACTERIZED BY USING CATHEPSIN K INHIBITOR WITH PTH
|
CN101437524B
(zh)
*
|
2004-09-14 |
2012-01-11 |
法莫赛特股份有限公司 |
2'-氟-2'-烷基-取代的或其它任选取代的呋喃核糖基嘧啶和嘌呤及其衍生物的制备
|
US7531560B2
(en)
|
2004-11-10 |
2009-05-12 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Anti-cytokine heterocyclic compounds
|
JP2008527031A
(ja)
|
2005-01-19 |
2008-07-24 |
バイオリポックス エービー |
炎症の治療に有用なピロロピリジン誘導体
|
GB0503054D0
(en)
|
2005-02-14 |
2005-03-23 |
Smithkline Beecham Corp |
Chemical compounds
|
WO2006091862A2
(en)
|
2005-02-24 |
2006-08-31 |
Kemia, Inc. |
Cytokine inhibitors and their use in therapy
|
EP1910363A4
(en)
|
2005-08-04 |
2010-05-26 |
Glaxosmithkline Llc |
INHIBITORS OF HIV INTEGRASE
|
TW201402124A
(zh)
|
2005-08-19 |
2014-01-16 |
Array Biopharma Inc |
作為類鐸受體(toll-like receptor)調節劑之8-經取代苯并氮雜呯
|
TWI382019B
(zh)
|
2005-08-19 |
2013-01-11 |
Array Biopharma Inc |
作為類鐸受體(toll-like receptor)調節劑之胺基二氮雜呯
|
BRPI0615934A2
(pt)
|
2005-09-16 |
2011-05-31 |
Arrow Therapeutics Ltd |
composto ou um sal farmaceuticamente aceitável do mesmo, uso de um derivado de bifenila, composição farmacêutica, e, produto
|
WO2007058990A2
(en)
|
2005-11-14 |
2007-05-24 |
Kemia, Inc. |
Therapy using cytokine inhibitors
|
ES2700433T3
(es)
|
2005-12-13 |
2019-02-15 |
Incyte Holdings Corp |
Derivados de pirrolo[2,3-d]pirimidina como inhibidores de quinasas Janus
|
CN101007798B
(zh)
|
2006-01-24 |
2011-01-26 |
中国人民解放军军事医学科学院毒物药物研究所 |
苯并间二氧杂环戊烯衍生物及其制备方法和医药用途
|
JP5441416B2
(ja)
|
2006-02-14 |
2014-03-12 |
プレジデント アンド フェロウズ オブ ハーバード カレッジ |
二官能性ヒストンデアセチラーゼインヒビター
|
US8017612B2
(en)
|
2006-04-18 |
2011-09-13 |
Japan Tobacco Inc. |
Piperazine compound and use thereof as a HCV polymerase inhibitor
|
TW200815437A
(en)
|
2006-06-13 |
2008-04-01 |
Bayer Schering Pharma Ag |
Substituted aminopyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
|
EP1867647A1
(en)
|
2006-06-13 |
2007-12-19 |
Bayer Schering Pharma Aktiengesellschaft |
Substituted aminopyrazolopyridines and salts thereof, their preparations and pharmaceutical compositions comprising them.
|
TW200815438A
(en)
|
2006-06-13 |
2008-04-01 |
Bayer Schering Pharma Ag |
Substituted pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
|
EP1867648A1
(en)
|
2006-06-13 |
2007-12-19 |
Bayer Schering Pharma Aktiengesellschaft |
Substituted aminopyrazolopyridines and salts thereof, their preparations and pharmaceutical compositions comprising them.
|
EP1870410A1
(en)
|
2006-06-13 |
2007-12-26 |
Bayer Schering Pharma Aktiengesellschaft |
Substituted arylpyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
|
WO2007147336A1
(en)
|
2006-06-13 |
2007-12-27 |
Shanghai Institue Of Materia Medica, Chinese Academy Of Sciences |
Heterocyclic non-nucleoside compounds, their peparation, pharmaceutical composition and their use as antiviral agents
|
US8158810B2
(en)
|
2006-07-27 |
2012-04-17 |
Gilead Sciences, Inc. |
ALDH-2 inhibitors in the treatment of addiction
|
EP1900739A1
(en)
|
2006-08-30 |
2008-03-19 |
Cellzome Ag |
Diazolodiazine derivatives as kinase inhibitors
|
EP1932845A1
(en)
|
2006-12-15 |
2008-06-18 |
Bayer Schering Pharma Aktiengesellschaft |
3-H-pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
|
CA2672367A1
(en)
|
2006-12-15 |
2008-06-19 |
Bayer Schering Pharma Aktiengesellschaft |
3-h-pyrazolopyridines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
|
WO2008091681A2
(en)
|
2007-01-23 |
2008-07-31 |
Housey Gerard M |
Theramutein modulators
|
DK2134689T3
(da)
|
2007-03-16 |
2014-06-30 |
Scripps Research Inst |
Inhibitorer af fokal adhæsionskinase
|
AR065901A1
(es)
|
2007-04-02 |
2009-07-08 |
Palau Pharma Sa |
Derivados de pirrolipirimidina
|
CA2683398A1
(en)
|
2007-04-10 |
2008-10-16 |
Sgx Pharmaceuticals, Inc. |
Fused ring heterocycle kinase modulators
|
EP2170888B1
(en)
|
2007-06-29 |
2015-04-22 |
Gilead Sciences, Inc. |
Purine derivatives and their use as modulators of toll-like receptor 7
|
EP2185544B1
(en)
|
2007-07-19 |
2014-11-26 |
Cymabay Therapeutics, Inc. |
N-azacyclic substituted pyrrole, pyrazole, imidazole, triazole and tetrazole derivatives as agonists of the rup3 or gpr119 for the treatment of diabetes and metabolic disorders
|
EP2188272B1
(en)
|
2007-08-06 |
2016-02-24 |
reMynd NV |
Phenyl- and benzylthiazolylpiperazine derivatives for the treatment of neurodegenerative diseases
|
WO2009034433A2
(en)
|
2007-09-10 |
2009-03-19 |
Glenmark Pharmaceuticals, S.A. |
3-azabicyclo [3.1.0] hexane derivatives as vanilloid receptor ligands
|
KR20100072024A
(ko)
|
2007-09-14 |
2010-06-29 |
메틸진 인크. |
히스톤 탈아세틸화 효소 hdac1, hdac2 및/또는 hdac3의 선택적 억제제 및 미세관 안정화제로의 암 병용 치료법
|
CN101910170A
(zh)
|
2007-10-22 |
2010-12-08 |
记忆药物公司 |
用于治疗疾病的烟碱性乙酰胆碱受体的(1,4-二氮杂双环[3.2.2]壬-6-烯-4-基)-杂环基-甲酮配体
|
WO2009070485A1
(en)
|
2007-11-29 |
2009-06-04 |
Boehringer Ingelheim International Gmbh |
DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-α]IMIDAZOLE-3- CARBOXYLIC ACID AMIDES
|
EP2070929A1
(en)
|
2007-12-11 |
2009-06-17 |
Bayer Schering Pharma Aktiengesellschaft |
Alkynylaryl compounds and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same
|
RU2544856C2
(ru)
|
2008-01-25 |
2015-03-20 |
Сергей Олегович Бачурин |
НОВЫЕ ПРОИЗВОДНЫЕ 2,3,4,5-ТЕТРАГИДРО-1-ПИРИДО[4,3-b]ИНДОЛА И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
|
CA2716514A1
(en)
|
2008-02-21 |
2009-08-27 |
Sequoia Pharmaceuticals, Inc. |
Hiv protease inhibitor and cytochrome p450 inhibitor combinations
|
WO2009126691A1
(en)
|
2008-04-09 |
2009-10-15 |
Infinity Pharmaceuticals, Inc |
Inhibitors of fatty acid amide hydrolase
|
WO2009133834A1
(ja)
|
2008-04-28 |
2009-11-05 |
塩野義製薬株式会社 |
血管内皮リパーゼ阻害活性を有するケトアミド誘導体
|
US20090298834A1
(en)
|
2008-06-02 |
2009-12-03 |
Hassan Pajouhesh |
4-(aminomethyl)cyclohexanamine derivatives as calcium channel blockers
|
BRPI0914891A2
(pt)
|
2008-06-20 |
2015-11-24 |
Metabolex Inc |
agonistas de aril gpr119 e usos dos mesmos
|
SI2824100T1
(en)
|
2008-07-08 |
2018-06-29 |
Incyte Holdings Corporation |
1,2,5-oxadiazoles as inhibitors of indolamine 2,3-dioxygenase
|
JO3041B1
(ar)
|
2008-07-25 |
2016-09-05 |
Galapagos Nv |
مركبات جديدة مفيدة لمعالجة الأمراض التنكسية والالتهابية
|
FR2934593B1
(fr)
|
2008-07-29 |
2010-09-10 |
Pf Medicament |
Derives dimeriques d'artemisinine et application en therapie anticancereuse
|
PL2313111T3
(pl)
|
2008-08-01 |
2014-08-29 |
Ventirx Pharmaceuticals Inc |
Preparaty agonistów receptora Toll-podobnego i ich zastosowanie
|
EA201170351A1
(ru)
|
2008-08-21 |
2011-08-30 |
Рихтер Гедеон Нирт. |
Способы лечения невропатической боли
|
WO2010029299A1
(en)
|
2008-09-12 |
2010-03-18 |
Biolipox Ab |
Pyrimidinone derivaties for use as medicaments
|
AR073397A1
(es)
|
2008-09-23 |
2010-11-03 |
Palau Pharma Sa |
Derivados de (r) -3- (n,n-dimetilamino) pirrolidina
|
ES2570429T3
(es)
|
2008-10-16 |
2016-05-18 |
Univ California |
Inhibidores de heteroaril quinasa de anillo condensado
|
WO2010053998A1
(en)
|
2008-11-05 |
2010-05-14 |
Xenon Pharmaceuticals, Inc. |
Spiro-condensed indole derivatives as sodium channel inhibitors
|
PL2364314T3
(pl)
|
2008-12-09 |
2014-08-29 |
Gilead Sciences Inc |
Modulatory receptorów Toll-podobnych
|
WO2010068287A2
(en)
|
2008-12-11 |
2010-06-17 |
Angion Biomedica Corp. |
Small molecule modulators of hepatocyte growth factor (scatter factor) activity
|
TW201038569A
(en)
|
2009-02-16 |
2010-11-01 |
Abbott Gmbh & Co Kg |
Heterocyclic compounds, pharmaceutical compositions containing them, and their use in therapy
|
TW201035102A
(en)
|
2009-03-04 |
2010-10-01 |
Gruenethal Gmbh |
Sulfonylated tetrahydroazolopyrazines and their use as medicinal products
|
US8822476B2
(en)
|
2009-04-02 |
2014-09-02 |
Merck Patent Gmbh |
Piperidine and piperazine derivatives as autotaxin inhibitors
|
SG174518A1
(en)
|
2009-04-02 |
2011-10-28 |
Merck Patent Gmbh |
Autotaxin inhibitors
|
WO2011003418A1
(en)
|
2009-07-08 |
2011-01-13 |
Leo Pharma A/S |
Heterocyclic compounds as jak receptor and protein tyrosine kinase inhibitors
|
DK2467377T3
(en)
|
2009-08-18 |
2017-04-03 |
Ventirx Pharmaceuticals Inc |
SUBSTITUTED BENZOAZEPINS AS MODULATORS OF TOLL-LIKE RECEPTORS
|
RU2580320C2
(ru)
|
2009-08-18 |
2016-04-10 |
Вентиркс Фармасьютикалз, Инк. |
Замещенные бензоазепины в качестве модуляторов toll-подобного рецептора
|
DK2480552T3
(en)
|
2009-09-21 |
2017-02-20 |
Gilead Sciences Inc |
2 'FLUOROUS-SUBSTITUTED CARBA NUCLEOSIDE ANALYSIS FOR ANTIVIRAL TREATMENT
|
WO2011048611A1
(en)
|
2009-10-07 |
2011-04-28 |
Torrent Pharmaceuticals Limited |
Novel fused pyridazine derivatives
|
NO2491035T3
(ar)
|
2009-10-22 |
2018-01-27 |
|
|
BR112012016570A2
(pt)
|
2010-01-07 |
2016-04-05 |
Polymedix Inc |
composto, composição farmacêutica, método para antagonizar a heparina não fracionada, heparina de peso molecular baixo, ou derivado de heparina /heparina de peso molecular baixo, e, uso do composto
|
WO2011087051A1
(ja)
|
2010-01-14 |
2011-07-21 |
国立大学法人金沢大学 |
S1p2受容体アンタゴニストを含む粥状動脈硬化治療薬
|
WO2011106106A2
(en)
|
2010-02-24 |
2011-09-01 |
Oryzon Genomics, S.A. |
Lysine demethylase inhibitors for diseases and disorders associated with hepadnaviridae
|
CN102869661B
(zh)
|
2010-03-18 |
2015-08-05 |
韩国巴斯德研究所 |
抗感染化合物
|
KR20130069640A
(ko)
|
2010-04-23 |
2013-06-26 |
키네타, 인크. |
항-바이러스 화합물
|
US8871799B2
(en)
|
2010-04-23 |
2014-10-28 |
Kineta, Inc. |
Iminochromene anti-viral compounds
|
AR081039A1
(es)
|
2010-05-14 |
2012-05-30 |
Osi Pharmaceuticals Llc |
Inhibidores biciclicos fusionados de quinasa
|
WO2011146401A1
(en)
|
2010-05-17 |
2011-11-24 |
Intermune, Inc. |
Novel inhibitors of hepatitis c virus replication
|
WO2011145669A1
(ja)
|
2010-05-19 |
2011-11-24 |
大日本住友製薬株式会社 |
アミド誘導体
|
HUE030720T2
(en)
|
2010-05-31 |
2017-06-28 |
Ono Pharmaceutical Co |
Purinone derivative as btk kinase inhibitor
|
US8975232B2
(en)
|
2010-07-29 |
2015-03-10 |
President And Fellows Of Harvard College |
Macrocyclic kinase inhibitors and uses thereof
|
WO2012014114A1
(en)
|
2010-07-30 |
2012-02-02 |
Ranbaxy Laboratories Limited |
Matrix metalloproteinase inhibitors
|
WO2012020567A1
(en)
|
2010-08-09 |
2012-02-16 |
Raqualia Pharma Inc. |
Acyl piperazine derivatives as ttx-s blockers
|
AU2011297961B2
(en)
|
2010-09-02 |
2015-07-02 |
Merck Patent Gmbh |
Pyrazolopyridinone derivatives as LPA receptor antagonists
|
CA2812319A1
(en)
|
2010-09-24 |
2012-03-29 |
Ranbaxy Laboratories Limited |
Matrix metalloproteinase inhibitors
|
WO2012050868A1
(en)
|
2010-09-28 |
2012-04-19 |
Georgia Tech Research Corporation |
Histone deacetylase (hdac) inhibitors targeting prostate tumors and methods of making and using thereof
|
CN107970451A
(zh)
|
2010-10-01 |
2018-05-01 |
帆德制药股份有限公司 |
Tlr激动剂和联合治疗的治疗应用
|
BR112013007678A2
(pt)
|
2010-10-01 |
2017-07-04 |
Ventirx Pharmaceuticals Inc |
método para tratamento de doenças alérgicas
|
EP2632898A4
(en)
|
2010-10-29 |
2014-04-02 |
Biogen Idec Inc |
HETEROCYCLIC TYROSINE KINASE HEMMER
|
AR084217A1
(es)
|
2010-12-10 |
2013-05-02 |
Gilead Sciences Inc |
Inhibidores macrociclicos de virus flaviviridae
|
TWI574687B
(zh)
|
2011-01-03 |
2017-03-21 |
古利斯股份有限公司 |
具有鋅結合部份之刺蝟拮抗劑
|
EP2663550B1
(en)
|
2011-01-12 |
2016-12-14 |
VentiRx Pharmaceuticals, Inc. |
Substituted benzoazepines as toll-like receptor modulators
|
PT2663555T
(pt)
|
2011-01-12 |
2017-03-23 |
Array Biopharma Inc |
Benzoazepinas substituídas como moduladores de recetores tipo-toll
|
US20120184572A1
(en)
|
2011-01-13 |
2012-07-19 |
Metabolex, Inc. |
Aryl gpr119 agonists and uses thereof
|
AU2012217616B2
(en)
|
2011-02-18 |
2017-03-02 |
Vertex Pharmaceuticals Incorporated |
Chroman - spirocyclic piperidine amides as modulators of ion channels
|
WO2012116135A2
(en)
|
2011-02-24 |
2012-08-30 |
Emory University |
Noggin blocking compositions for ossification and methods related thereto
|
US20140086839A1
(en)
|
2011-03-17 |
2014-03-27 |
Tel Hashomer Medical Research Infrastructure And Services Ltd. |
Quinolone analogs for treating autoimmune diseases
|
WO2012129562A2
(en)
|
2011-03-24 |
2012-09-27 |
The Scripps Research Institute |
Compounds and methods for inducing chondrogenesis
|
AU2012238564A1
(en)
|
2011-04-08 |
2013-09-26 |
Janssen Sciences Ireland Uc |
Pyrimidine derivatives for the treatment of viral infections
|
CN103957710B
(zh)
|
2011-05-16 |
2016-04-20 |
塞尔西优蒂克斯公司 |
用于治疗粘膜炎的化合物
|
US9156830B2
(en)
|
2011-05-17 |
2015-10-13 |
Shionogi & Co., Ltd. |
Heterocyclic compounds
|
EA028254B1
(ru)
|
2011-05-18 |
2017-10-31 |
Янссен Сайенсиз Айрлэнд Юси |
Хиназолиновые производные для лечения вирусных инфекций и дальнейших заболеваний
|
EP2710019B1
(en)
|
2011-05-19 |
2017-05-03 |
Gilead Sciences, Inc. |
Processes and intermediates for preparing anti-hiv agents
|
CA2833507A1
(en)
|
2011-06-07 |
2012-12-13 |
Dainippon Sumitomo Pharma Co., Ltd. |
Indazole- and pyrrolopyridine-derivative and pharmaceutical use thereof
|
US9399619B2
(en)
|
2011-07-01 |
2016-07-26 |
Baruch S. Blumberg Institute |
Sulfamoylbenzamide derivatives as antiviral agents against HBV infection
|
TWI454466B
(zh)
|
2011-07-22 |
2014-10-01 |
Ken Tsung Wong |
可用於有機薄膜太陽能電池之化合物及有機薄膜太陽能電池
|
KR102197165B1
(ko)
|
2011-07-29 |
2021-01-04 |
메르크 파텐트 게엠베하 |
전자 소자용 화합물
|
EP2758375A1
(en)
|
2011-09-23 |
2014-07-30 |
Advinus Therapeutics Limited |
Amide compounds, compositions and applications thereof
|
WO2013059278A2
(en)
|
2011-10-17 |
2013-04-25 |
Enanta Pharmaceuticals, Inc. |
Hepatitis c virus inhibitors
|
LT2786996T
(lt)
|
2011-11-29 |
2017-01-10 |
Ono Pharmaceutical Co., Ltd. |
Purinono darinio hidrochloridas
|
US20140288145A1
(en)
|
2011-12-05 |
2014-09-25 |
Brandeis University |
Treatment of amyloidosis by compounds that regulate retromer stabilization
|
DE102011121022A1
(de)
|
2011-12-13 |
2013-06-13 |
Merck Patent Gmbh |
Organische Sensibilisatoren für Up- Conversion
|
MX359634B
(es)
|
2011-12-21 |
2018-10-03 |
Novira Therapeutics Inc |
Agentes antivirales contra la hepatitis b.
|
TWI573792B
(zh)
|
2012-02-01 |
2017-03-11 |
歐陸斯迪公司 |
新穎治療劑
|
AU2013218072B2
(en)
|
2012-02-08 |
2017-08-31 |
Janssen Sciences Ireland Uc |
Piperidino-pyrimidine derivatives for the treatment of viral infections
|
WO2013144228A1
(en)
|
2012-03-29 |
2013-10-03 |
Basf Se |
Pesticidal methods using heterocyclic compounds and derivatives for combating animal pests
|
US20130267517A1
(en)
|
2012-03-31 |
2013-10-10 |
Hoffmann-La Roche Inc. |
Novel 4-methyl-dihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
|
EP2831060B1
(en)
|
2012-03-31 |
2016-05-04 |
F.Hoffmann-La Roche Ag |
Novel 4-methyl-dihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
|
WO2013161871A1
(ja)
|
2012-04-25 |
2013-10-31 |
興和株式会社 |
Tlr阻害作用を有するチオフェン誘導体
|
SG11201408045UA
(en)
|
2012-06-08 |
2015-01-29 |
Gilead Sciences Inc |
MACROCYCLIC INHIBITORS OF <i>FLAVIVIRIDAE</i> VIRUSES
|
AR091279A1
(es)
|
2012-06-08 |
2015-01-21 |
Gilead Sciences Inc |
Inhibidores macrociclicos de virus flaviviridae
|
ES2624223T3
(es)
|
2012-06-08 |
2017-07-13 |
Gilead Sciences, Inc. |
Inhibidores macrocíclicos de los virus flaviviridae
|
KR102216479B1
(ko)
|
2012-08-10 |
2021-02-17 |
얀센 사이언시즈 아일랜드 언리미티드 컴퍼니 |
바이러스 감염 또는 추가 질환의 치료를 위한 알킬피리미딘 유도체
|
WO2014031872A2
(en)
|
2012-08-23 |
2014-02-27 |
The Broad Institute, Inc. |
Small molecule inhibitors for treating parasitic infections
|
BR112015004192B1
(pt)
|
2012-08-28 |
2021-02-09 |
Janssen Sciences Ireland Uc |
sulfamoíl-arilamidas, composição farmacêutica que os compreende e uso das mesmas no tratamento da hepatite b
|
EP2890683B1
(en)
|
2012-08-28 |
2016-10-12 |
Janssen Sciences Ireland UC |
Fused bicyclic sulfamoyl derivatives and the use thereof as medicaments for the treatment of hepatitis b
|
EP2892899B1
(en)
|
2012-09-06 |
2018-03-21 |
Bristol-Myers Squibb Company |
Imidazopyridazine jak3 inhibitors and their use for the treatment of inflammatory and autoimmune diseases
|
WO2014037480A1
(en)
|
2012-09-10 |
2014-03-13 |
F. Hoffmann-La Roche Ag |
6-amino acid heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis b virus infection
|
WO2014045305A1
(en)
|
2012-09-21 |
2014-03-27 |
Advinus Therapeutics Limited |
Substituted fused tricyclic compounds, compositions and medicinal applications thereof
|
PT3023415T
(pt)
|
2012-10-02 |
2018-02-27 |
Gilead Sciences Inc |
Inibidores de desmetilases de histonas
|
PL2906563T3
(pl)
|
2012-10-10 |
2018-10-31 |
Janssen Sciences Ireland Uc |
Pochodne pirolo[3,2-d]pirymidyny do leczenia infekcji wirusowych i innych chorób
|
JP6297055B2
(ja)
|
2012-11-16 |
2018-03-20 |
ヤンセン・サイエンシズ・アイルランド・ユーシー |
ウイルス感染症の治療のための複素環置換2−アミノ−キナゾリン誘導体
|
MX2015007205A
(es)
|
2012-12-06 |
2016-03-31 |
Quanticel Pharmaceuticals Inc |
Inhibidores de la desmetilasa de histona.
|
EP2928459A4
(en)
|
2012-12-06 |
2016-10-26 |
Baruch S Blumberg Inst |
FUNCTIONALIZED BENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION
|
JP2014133739A
(ja)
|
2012-12-12 |
2014-07-24 |
Dainippon Sumitomo Pharma Co Ltd |
インダゾール誘導体またはピロロピリジン誘導体からなる医薬
|
JP6256772B2
(ja)
|
2012-12-19 |
2018-01-10 |
セルジーン クオンティセル リサーチ,インク. |
ヒストンデメチラーゼ阻害剤
|
US9271978B2
(en)
|
2012-12-21 |
2016-03-01 |
Zenith Epigenetics Corp. |
Heterocyclic compounds as bromodomain inhibitors
|
EA028774B1
(ru)
|
2012-12-21 |
2017-12-29 |
Квонтисел Фармасьютикалс, Инк. |
Ингибиторы гистондеметилазы
|
TWI598339B
(zh)
|
2012-12-24 |
2017-09-11 |
卡地拉保健有限公司 |
新穎喹啉酮衍生物
|
KR101942151B1
(ko)
|
2012-12-27 |
2019-01-24 |
드렉셀유니버시티 |
Hbv 감염에 대한 항바이러스 물질
|
CN105101970B
(zh)
|
2013-01-10 |
2018-11-20 |
维纳拓尔斯制药公司 |
β-内酰胺酶抑制剂
|
LT2951172T
(lt)
|
2013-01-29 |
2017-07-25 |
Redx Pharma Plc |
Piridino dariniai, kaip lengvai suyrantys rock inhibitoriai
|
EP2958900B1
(en)
|
2013-02-21 |
2019-04-10 |
Janssen Sciences Ireland Unlimited Company |
2-aminopyrimidine derivatives for the treatment of viral infections
|
GB201303109D0
(en)
|
2013-02-21 |
2013-04-10 |
Domainex Ltd |
Novel pyrimidine compounds
|
PL2961736T3
(pl)
|
2013-02-27 |
2018-08-31 |
Gilead Sciences, Inc. |
Inhibitory demetylaz histonowych
|
JP6466348B2
(ja)
|
2013-02-28 |
2019-02-06 |
ヤンセン・サイエンシズ・アイルランド・アンリミテッド・カンパニー |
スルファモイル−アリールアミドおよびb型肝炎を処置するための医薬品としてのその使用
|
WO2014165128A2
(en)
|
2013-03-12 |
2014-10-09 |
Novira Therapeutics, Inc. |
Hepatitis b antiviral agents
|
WO2014164708A1
(en)
|
2013-03-12 |
2014-10-09 |
Quanticel Pharmaceuticals, Inc. |
Histone dementhylase inhibitors
|
US10035801B2
(en)
|
2013-03-13 |
2018-07-31 |
Genentech, Inc. |
Pyrazolo compounds and uses thereof
|
EP2970340B1
(en)
|
2013-03-14 |
2020-02-12 |
Venatorx Pharmaceuticals, Inc. |
Beta-lactamase inhibitors
|
AU2014236711A1
(en)
|
2013-03-14 |
2015-09-17 |
Celgene Quanticel Research, Inc. |
Histone demethylase inhibitors
|
HUE034906T2
(hu)
|
2013-03-15 |
2018-03-28 |
Quanticel Pharmaceuticals Inc |
Hiszton-demetiláz inhibitorok
|
DK2981536T3
(en)
|
2013-04-03 |
2017-09-25 |
Janssen Sciences Ireland Uc |
N-PHENYLC CARBOXAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICINES FOR THE TREATMENT OF HEPATITIS B
|
WO2014179144A1
(en)
|
2013-04-29 |
2014-11-06 |
E. I. Du Pont De Nemours And Company |
Fungicidal heterocyclic compounds
|
MX2015015692A
(es)
|
2013-05-17 |
2016-03-04 |
Hoffmann La Roche |
Novedosas heteroarildihidropirimidinas, unidas por puentes en 6 para el tratamiento y la profilaxis de infeccion por el virus de hepatitis b.
|
JO3603B1
(ar)
|
2013-05-17 |
2020-07-05 |
Janssen Sciences Ireland Uc |
مشتقات سلفامويل بيرولاميد واستخدامها كادوية لمعالجة التهاب الكبد نوع بي
|
CN105960400B
(zh)
|
2013-05-17 |
2019-05-31 |
爱尔兰詹森科学公司 |
氨磺酰基噻吩酰胺衍生物及其作为药物用于治疗乙型肝炎的用途
|
JP6380862B2
(ja)
|
2013-06-28 |
2018-08-29 |
ベイジーン リミテッド |
複数種類のキナーゼの阻害剤としての縮合三環式アミド系化合物
|
JP6458018B2
(ja)
|
2013-07-02 |
2019-01-23 |
ファーマサイクリックス エルエルシー |
キナーゼ阻害剤としてのプリノン化合物
|
EP3357906B1
(en)
|
2013-07-25 |
2019-12-04 |
Janssen Sciences Ireland Unlimited Company |
Glyoxamide substituted pyrrolamide derivatives and the use thereof as medicaments for the treatment of hepatitis b
|
CN105979941A
(zh)
|
2013-08-20 |
2016-09-28 |
希望之城 |
用于治疗癌症的hdac8抑制剂
|
KR101715090B1
(ko)
|
2013-08-28 |
2017-03-13 |
한국화학연구원 |
신규한 화합물 또는 이의 약학적으로 허용가능한 염, 및 이를 유효성분으로 함유하는 인플루엔자 바이러스 감염으로 인한 질환의 예방 또는 치료용 약학적 조성물
|
WO2015051230A1
(en)
|
2013-10-04 |
2015-04-09 |
Drexel University |
Novel compositions useful for inhibiting hiv-1 infection and methods using same
|
JP6491202B2
(ja)
|
2013-10-18 |
2019-03-27 |
デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド |
サイクリン依存性キナーゼ7(cdk7)の多環阻害剤
|
WO2015057945A1
(en)
|
2013-10-18 |
2015-04-23 |
Indiana University Research And Technology Corporation |
Hepatitis b viral assembly effectors
|
CA2923712C
(en)
|
2013-10-23 |
2021-11-02 |
Janssen Sciences Ireland Uc |
Carboxamide derivatives and the use thereof as medicaments for the treatment of hepatitis b
|
US9115113B2
(en)
|
2013-11-14 |
2015-08-25 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
WO2015085238A1
(en)
|
2013-12-05 |
2015-06-11 |
The Regents Of The University Of California, A California Corporation |
Inhibitors of lpxc
|
US9169212B2
(en)
|
2014-01-16 |
2015-10-27 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
US9181288B2
(en)
|
2014-01-16 |
2015-11-10 |
Novira Therapeutics, Inc. |
Azepane derivatives and methods of treating hepatitis B infections
|
CA2931329A1
(en)
|
2014-01-30 |
2015-08-06 |
F. Hoffmann-La Roche Ag |
Novel dihydroquinolizinones for the treatment and prophylaxis of hepatitis b virus infection
|
AU2015214096B2
(en)
|
2014-02-05 |
2021-02-11 |
Novira Therapeutics, Inc. |
Combination therapy for treatment of HBV infections
|
CA2932551A1
(en)
|
2014-02-06 |
2015-08-13 |
Janssen Sciences Ireland Uc |
Sulphamoylpyrrolamide derivatives and the use thereof as medicaments for the treatment of hepatitis b
|
AU2015235944B2
(en)
|
2014-03-27 |
2020-06-25 |
Vanderbilt University |
Substituted indole Mcl-1 inhibitors
|
US9400280B2
(en)
|
2014-03-27 |
2016-07-26 |
Novira Therapeutics, Inc. |
Piperidine derivatives and methods of treating hepatitis B infections
|
RU2016146365A
(ru)
|
2014-05-13 |
2018-06-19 |
Ф. Хоффманн-Ля Рош Аг |
Новые дигидрохинолизиноны для лечения и профилактики заражения вирусом гепатита b
|
US9938301B2
(en)
|
2014-05-30 |
2018-04-10 |
Qilu Pharmaceutical Co., Ltd. |
Dihydropyrimido fused ring derivative as HBV inhibitor
|
CN106661005A
(zh)
|
2014-07-16 |
2017-05-10 |
诺沃根公司 |
作为抗癌药物的功能化的和取代的吲哚
|
WO2016023877A1
(en)
|
2014-08-14 |
2016-02-18 |
F. Hoffmann-La Roche Ag |
Novel pyridazones and triazinones for the treatment and prophylaxis of hepatitis b virus infection
|
CN112898308A
(zh)
|
2014-08-15 |
2021-06-04 |
正大天晴药业集团股份有限公司 |
作为tlr7激动剂的吡咯并嘧啶化合物
|
BR112017003442A2
(pt)
|
2014-08-27 |
2017-11-28 |
Gilead Sciences Inc |
compostos e métodos para inibir histona desmetilases
|
CN107912040B
(zh)
|
2014-10-10 |
2021-04-06 |
基因泰克公司 |
作为组蛋白脱甲基酶抑制剂的吡咯烷酰胺化合物
|
US9637485B2
(en)
|
2014-11-03 |
2017-05-02 |
Hoffmann-La Roche Inc. |
6,7-dihydrobenzo[a]quinolizin-2-one derivatives for the treatment and prophylaxis of hepatitis B virus infection
|
US10435402B2
(en)
|
2015-01-08 |
2019-10-08 |
Advinus Therapeutics Limited |
Bicyclic compounds, compositions and medicinal applications thereof
|
MA41338B1
(fr)
|
2015-01-16 |
2019-07-31 |
Hoffmann La Roche |
Composés de pyrazine pour le traitement de maladies infectieuses
|
WO2016128908A1
(en)
|
2015-02-12 |
2016-08-18 |
Advinus Therapeutics Limited |
Bicyclic compounds, compositions and medicinal applications thereof
|
EP3302795B1
(de)
|
2015-05-28 |
2019-07-31 |
Basf Se |
Verfahren zur homogen katalysierten reduktiven aminierung von carbonyl-verbindungen
|
WO2016201440A1
(en)
|
2015-06-12 |
2016-12-15 |
The Regents Of The University Of California |
Spiroindolinones and therapeutic uses thereof
|
US10702527B2
(en)
|
2015-06-12 |
2020-07-07 |
Dana-Farber Cancer Institute, Inc. |
Combination therapy of transcription inhibitors and kinase inhibitors
|
US10875876B2
(en)
|
2015-07-02 |
2020-12-29 |
Janssen Sciences Ireland Uc |
Cyclized sulfamoylarylamide derivatives and the use thereof as medicaments for the treatment of hepatitis B
|
WO2017012379A1
(zh)
|
2015-07-20 |
2017-01-26 |
中国科学院上海有机化学研究所 |
草酸酰胺类配体及其在铜催化芳基卤代物偶联反应中的用途
|
WO2017015451A1
(en)
|
2015-07-22 |
2017-01-26 |
Enanta Pharmaceuticals, Inc. |
Hepatitis b antiviral agents
|
US10029995B2
(en)
|
2015-09-03 |
2018-07-24 |
Forma Therapeutics, Inc. |
[6,6] fused bicyclic HDAC8 inhibitors
|
GB201516614D0
(en)
|
2015-09-18 |
2015-11-04 |
Redx Pharma Plc |
Antibacterial compounds
|
BR112018008880B1
(pt)
|
2015-11-05 |
2023-01-17 |
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. |
7-(tiazol-5-il) pirrolopirimidina, seu uso, e composição farmacêutica
|
JP6621933B2
(ja)
|
2015-11-09 |
2019-12-18 |
ギリアード サイエンシス インコーポレーテッド |
ヒト免疫不全ウイルスを処置するための治療組成物
|
US10662186B2
(en)
|
2015-12-31 |
2020-05-26 |
Shanghai Pharmaceuticals Holding Co., Ltd. |
Substituted pyrimidines as cyclin-dependent kinase inhibitors
|
PE20190118A1
(es)
*
|
2016-03-09 |
2019-01-16 |
Univ Emory |
Eliminacion del virus de la hepatitis b con agentes antivirales
|
HUE061989T2
(hu)
|
2016-03-16 |
2023-09-28 |
Kura Oncology Inc |
Szubsztituált tieno[2,3-D]pirimidin származékok mint menin-MLL inhibitorai és alkalmazási eljárások
|
WO2017161524A1
(zh)
|
2016-03-23 |
2017-09-28 |
华东理工大学 |
丙酮酸脱氢酶激酶抑制剂及其应用
|
CN107226805A
(zh)
|
2016-03-24 |
2017-10-03 |
北京天诚医药科技有限公司 |
芳香族酰胺类衍生物、其制备方法及其在医药上的应用
|
ES2946970T3
(es)
|
2016-03-31 |
2023-07-28 |
Vertex Pharma |
Regulador de conductancia transmembrana de moduladores de fibrosis quística
|
TW201808888A
(zh)
|
2016-05-05 |
2018-03-16 |
嘉來克生命科學有限責任公司 |
整合應激途徑之調節劑
|
WO2017209265A1
(ja)
|
2016-06-03 |
2017-12-07 |
塩野義製薬株式会社 |
二環性複素環誘導体およびそれらを含有する医薬組成物
|
JP2019521972A
(ja)
|
2016-06-10 |
2019-08-08 |
エナンタ ファーマシューティカルズ インコーポレイテッド |
B型肝炎抗ウイルス剤
|
CN107537157B
(zh)
|
2016-06-29 |
2022-05-17 |
无敌媒体有限公司 |
用于减少具有虚拟货币的电子游戏中的欺诈的***和方法
|
JOP20190024A1
(ar)
|
2016-08-26 |
2019-02-19 |
Gilead Sciences Inc |
مركبات بيروليزين بها استبدال واستخداماتها
|
US10836769B2
(en)
*
|
2018-02-26 |
2020-11-17 |
Gilead Sciences, Inc. |
Substituted pyrrolizine compounds and uses thereof
|