ITFI20040174A1 - Derivati arilsolfonammidici dell'acido idrossammico ad azione inibitoria di metalloproteinasi - Google Patents

Derivati arilsolfonammidici dell'acido idrossammico ad azione inibitoria di metalloproteinasi

Info

Publication number
ITFI20040174A1
ITFI20040174A1 IT000174A ITFI20040174A ITFI20040174A1 IT FI20040174 A1 ITFI20040174 A1 IT FI20040174A1 IT 000174 A IT000174 A IT 000174A IT FI20040174 A ITFI20040174 A IT FI20040174A IT FI20040174 A1 ITFI20040174 A1 IT FI20040174A1
Authority
IT
Italy
Prior art keywords
derivatives
hydroxamic acid
arytholphonamidic
metalloproteinase
inhibitory action
Prior art date
Application number
IT000174A
Other languages
English (en)
Inventor
Ivano Bertini
Marco Fragai
Conte Mauro Lo
Claudio Luchinat
Cristina Nativi
Chiara Venturi
Original Assignee
Protera S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Protera S R L filed Critical Protera S R L
Priority to IT000174A priority Critical patent/ITFI20040174A1/it
Publication of ITFI20040174A1 publication Critical patent/ITFI20040174A1/it
Priority to EP05769876A priority patent/EP1781601B1/en
Priority to PCT/EP2005/053722 priority patent/WO2006013193A2/en
Priority to RU2007107872/04A priority patent/RU2406721C2/ru
Priority to CA002580235A priority patent/CA2580235A1/en
Priority to MX2007001269A priority patent/MX2007001269A/es
Priority to CNA2005800336789A priority patent/CN101076514A/zh
Priority to AT05769876T priority patent/ATE492530T1/de
Priority to DE602005025495T priority patent/DE602005025495D1/de
Priority to US11/659,431 priority patent/US7772430B2/en
Priority to AU2005268765A priority patent/AU2005268765B2/en
Priority to JP2007524333A priority patent/JP2008509108A/ja
Priority to EP10188800A priority patent/EP2308837A3/en
Priority to BRPI0514030-7A priority patent/BRPI0514030A/pt
Priority to ZA200701798A priority patent/ZA200701798B/xx
Priority to US12/849,981 priority patent/US20100298439A1/en
Priority to RU2010136061/04A priority patent/RU2010136061A/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/02—Monosaccharides
IT000174A 2004-08-03 2004-08-03 Derivati arilsolfonammidici dell'acido idrossammico ad azione inibitoria di metalloproteinasi ITFI20040174A1 (it)

Priority Applications (17)

Application Number Priority Date Filing Date Title
IT000174A ITFI20040174A1 (it) 2004-08-03 2004-08-03 Derivati arilsolfonammidici dell'acido idrossammico ad azione inibitoria di metalloproteinasi
BRPI0514030-7A BRPI0514030A (pt) 2004-08-03 2005-07-29 derivados de ácido hidroxámico substituìdo por arilssulfonamida, como inibidores de metaloproteinases de matrizes
CNA2005800336789A CN101076514A (zh) 2004-08-03 2005-07-29 作为基质金属蛋白酶抑制剂的芳基磺酰氨基取代的异羟肟酸衍生物
DE602005025495T DE602005025495D1 (de) 2004-08-03 2005-07-29 Derivate einer arylsulfonamidosubstituierten hydroxamsäure als matrixmetalloproteinaseinhibitoren
RU2007107872/04A RU2406721C2 (ru) 2004-08-03 2005-07-29 Производные арилсульфонамидозамещенной гидроксамовой кислоты в качестве ингибиторов металлопротеиназ матрикса
CA002580235A CA2580235A1 (en) 2004-08-03 2005-07-29 Derivatives of arylsulfonamido-substituted hydroxamic acid as matrix metalloproteinases inhibitors
MX2007001269A MX2007001269A (es) 2004-08-03 2005-07-29 Derivados de acido hidroxamico sustituido por arilsulfonamido como inhibidores de metaloproteinasas de matriz.
EP05769876A EP1781601B1 (en) 2004-08-03 2005-07-29 Derivatives of arylsulfonamido-substituted hydroxamic acid as matrix metalloproteinases inhibitors
AT05769876T ATE492530T1 (de) 2004-08-03 2005-07-29 Derivate einer arylsulfonamidosubstituierten hydroxamsäure als matrixmetalloproteinaseinhibitoren
PCT/EP2005/053722 WO2006013193A2 (en) 2004-08-03 2005-07-29 Derivatives of arylsulfonamido-substituted hydroxamic acid as matrix metalloproteinases inhibitors
US11/659,431 US7772430B2 (en) 2004-08-03 2005-07-29 Derivatives of arylsulfonamido-substituted hydroxamic acid as matrix metalloproteinases inhibitors
AU2005268765A AU2005268765B2 (en) 2004-08-03 2005-07-29 Derivatives of arylsulfonamido-substituted hydroxamic acid as matrix metalloproteinases inhibitors
JP2007524333A JP2008509108A (ja) 2004-08-03 2005-07-29 マトリックスメタロプロテイナーゼの阻害剤としての、アリールスルフォンアミド置換ヒドロキサム酸の誘導体
EP10188800A EP2308837A3 (en) 2004-08-03 2005-07-29 Derivatives of arylsulfonamido-substituted hydroxamic acid as matrix metalloproteinases inhibitors
ZA200701798A ZA200701798B (en) 2004-08-03 2007-02-28 Derivatives of arylsulfonamido-substituted hydroxamic acid as matrix metalioproteinases inhibitors
US12/849,981 US20100298439A1 (en) 2004-08-03 2010-08-04 Derivatives of arylsulfonamido-substituted hydroxamic acid as matrix metalloproteinases inhibitors
RU2010136061/04A RU2010136061A (ru) 2004-08-03 2010-08-31 Производные арилсульфонамидозамещенной гидроксамовой кислоты в качестве ингибиторов металлопротеиназ матрикса

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000174A ITFI20040174A1 (it) 2004-08-03 2004-08-03 Derivati arilsolfonammidici dell'acido idrossammico ad azione inibitoria di metalloproteinasi

Publications (1)

Publication Number Publication Date
ITFI20040174A1 true ITFI20040174A1 (it) 2004-11-03

Family

ID=35787488

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000174A ITFI20040174A1 (it) 2004-08-03 2004-08-03 Derivati arilsolfonammidici dell'acido idrossammico ad azione inibitoria di metalloproteinasi

Country Status (14)

Country Link
US (2) US7772430B2 (it)
EP (2) EP2308837A3 (it)
JP (1) JP2008509108A (it)
CN (1) CN101076514A (it)
AT (1) ATE492530T1 (it)
AU (1) AU2005268765B2 (it)
BR (1) BRPI0514030A (it)
CA (1) CA2580235A1 (it)
DE (1) DE602005025495D1 (it)
IT (1) ITFI20040174A1 (it)
MX (1) MX2007001269A (it)
RU (2) RU2406721C2 (it)
WO (1) WO2006013193A2 (it)
ZA (1) ZA200701798B (it)

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* Cited by examiner, † Cited by third party
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KR20110040911A (ko) * 2008-07-14 2011-04-20 노파르티스 아게 선택적 히드록삼산계 ｍｍｐ-12 및 ｍｍｐ-13 억제제
DE102011088926A1 (de) * 2011-12-19 2013-06-20 Beiersdorf Ag Haarstylingformulierung zur Erstellung eines flexiblen Haltes durch Einsatz von Octanohydroxamsäure
DK2797942T3 (en) * 2011-12-28 2018-12-10 Galectin Therapeutics Inc Composition of Hitherto-Unknown Carbohydrate Drugs for the Treatment of Human Diseases
EP2907512A1 (en) 2014-02-14 2015-08-19 Commissariat A L'energie Atomique Et Aux Energies Alternatives Inhibitors of MMP-12 as antiviral Agents
CN105728047B (zh) * 2016-03-24 2017-12-26 万华化学集团股份有限公司 一种氢甲酰化催化剂及其制备方法和应用
JP2017210442A (ja) * 2016-05-26 2017-11-30 イノレックス インベストメント コーポレイション マトリックスメタロプロテイナーゼを阻害して皮膚の老化を軽減する方法及び関連の相乗的組成物
IT201600083975A1 (it) * 2016-08-09 2018-02-09 Consorzio Interuniversitario Naz Per La Scienza E Tecnologia Dei Materiali Acido ialuronico funzionalizzato
JP6541118B1 (ja) * 2018-04-27 2019-07-10 株式会社成和化成 化粧品基材および該化粧品基材を含有する毛髪用化粧品、美白剤
LV15485B (lv) * 2018-09-13 2020-06-20 Latvijas Organiskās Sintēzes Institūts Selenofēnhromenonu hidroksāmskābes, to izgatavošana un izmantošana angioģenēzes inhibīcijā

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LU68901A1 (it) 1973-11-30 1975-08-20
US5506242A (en) * 1993-01-06 1996-04-09 Ciba-Geigy Corporation Arylsufonamido-substituted hydroxamic acids
US5455258A (en) 1993-01-06 1995-10-03 Ciba-Geigy Corporation Arylsulfonamido-substituted hydroxamic acids
KR100338857B1 (ko) * 1996-01-23 2002-05-30 시오노 요시히코 술폰화 아미노산 유도체 및 이를 함유한메탈로프로테이나제 저해제
WO1997045402A1 (fr) * 1996-05-24 1997-12-04 Ono Pharmaceutical Co., Ltd. Derives de phenylsulfonamide
ATE212619T1 (de) 1996-10-22 2002-02-15 Upjohn Co Alpha-amino sulfonyl hydroxamsäure als matrix metalloproteinase inhibitoren
PL335027A1 (en) * 1997-02-03 2000-03-27 Pfizer Prod Inc Derivatives of arylsulphonylamino hydroxamic acid
WO1998050348A1 (en) * 1997-05-09 1998-11-12 Agouron Pharmaceuticals, Inc. Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses
AU746877B2 (en) * 1997-07-31 2002-05-02 Procter & Gamble Company, The Acyclic metalloprotease inhibitors
JPH11199512A (ja) 1997-10-24 1999-07-27 Pfizer Prod Inc 変形性関節症および他のｍｍｐ媒介疾患の治療のためのｍｍｐ−１３選択的阻害剤の使用
PA8469601A1 (es) * 1998-04-10 2000-09-29 Pfizer Prod Inc Procedimiento para alquilar sulfonamidas impedidas estericamente
RU2232751C2 (ru) * 1998-12-22 2004-07-20 Ф.Хоффманн-Ля Рош Аг Производные сульфонамидов и фармацевтическая композиция
DE59912745D1 (de) 1998-12-28 2005-12-08 Celanese Ventures Gmbh Verwendung von wasserunlöslichen linearen poly-alpha-glucan als uv-filter
FR2799964B1 (fr) 1999-10-22 2002-07-26 Oreal Emulsions contenant au moins un filtre uv organique insoluble et un polymere associatif
ES2264985T3 (es) 2000-05-10 2007-02-01 Ciba Specialty Chemicals Holding Inc. Compuestos sililados como precursores para composiciones de autobronceado.
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Also Published As

Publication number Publication date
EP1781601B1 (en) 2010-12-22
US7772430B2 (en) 2010-08-10
CN101076514A (zh) 2007-11-21
EP1781601A2 (en) 2007-05-09
WO2006013193A8 (en) 2010-07-29
EP2308837A3 (en) 2011-04-20
BRPI0514030A (pt) 2008-05-27
MX2007001269A (es) 2007-07-16
AU2005268765B2 (en) 2011-08-04
CA2580235A1 (en) 2006-02-09
DE602005025495D1 (de) 2011-02-03
ATE492530T1 (de) 2011-01-15
WO2006013193A2 (en) 2006-02-09
US20100298439A1 (en) 2010-11-25
RU2010136061A (ru) 2012-03-10
RU2406721C2 (ru) 2010-12-20
RU2007107872A (ru) 2008-09-10
US20080249032A1 (en) 2008-10-09
WO2006013193A3 (en) 2006-08-31
AU2005268765A1 (en) 2006-02-09
EP2308837A2 (en) 2011-04-13
ZA200701798B (en) 2008-08-27
JP2008509108A (ja) 2008-03-27

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