ZA200701798B - Derivatives of arylsulfonamido-substituted hydroxamic acid as matrix metalioproteinases inhibitors - Google Patents

Derivatives of arylsulfonamido-substituted hydroxamic acid as matrix metalioproteinases inhibitors

Info

Publication number
ZA200701798B
ZA200701798B ZA200701798A ZA200701798A ZA200701798B ZA 200701798 B ZA200701798 B ZA 200701798B ZA 200701798 A ZA200701798 A ZA 200701798A ZA 200701798 A ZA200701798 A ZA 200701798A ZA 200701798 B ZA200701798 B ZA 200701798B
Authority
ZA
South Africa
Prior art keywords
arylsulfonamido
derivatives
hydroxamic acid
inhibitors
substituted hydroxamic
Prior art date
Application number
ZA200701798A
Other languages
English (en)
Inventor
Bertini Ivano
Fragai Marco
Lo Conte Mauro
Luchinat Claudio
Nativi Cristina
Venturi Chiara
Original Assignee
Abiogen Pharma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abiogen Pharma Spa filed Critical Abiogen Pharma Spa
Publication of ZA200701798B publication Critical patent/ZA200701798B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
    • C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
    • C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
    • C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
    • C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/02—Monosaccharides
ZA200701798A 2004-08-03 2007-02-28 Derivatives of arylsulfonamido-substituted hydroxamic acid as matrix metalioproteinases inhibitors ZA200701798B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000174A ITFI20040174A1 (it) 2004-08-03 2004-08-03 Derivati arilsolfonammidici dell'acido idrossammico ad azione inibitoria di metalloproteinasi

Publications (1)

Publication Number Publication Date
ZA200701798B true ZA200701798B (en) 2008-08-27

Family

ID=35787488

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200701798A ZA200701798B (en) 2004-08-03 2007-02-28 Derivatives of arylsulfonamido-substituted hydroxamic acid as matrix metalioproteinases inhibitors

Country Status (14)

Country Link
US (2) US7772430B2 (xx)
EP (2) EP1781601B1 (xx)
JP (1) JP2008509108A (xx)
CN (1) CN101076514A (xx)
AT (1) ATE492530T1 (xx)
AU (1) AU2005268765B2 (xx)
BR (1) BRPI0514030A (xx)
CA (1) CA2580235A1 (xx)
DE (1) DE602005025495D1 (xx)
IT (1) ITFI20040174A1 (xx)
MX (1) MX2007001269A (xx)
RU (2) RU2406721C2 (xx)
WO (1) WO2006013193A2 (xx)
ZA (1) ZA200701798B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110112076A1 (en) 2008-07-14 2011-05-12 Mcquire Leslie Wighton Selective hydroxamic acid based mmp-12 and mmp-13 inhibitors
DE102011088926A1 (de) * 2011-12-19 2013-06-20 Beiersdorf Ag Haarstylingformulierung zur Erstellung eines flexiblen Haltes durch Einsatz von Octanohydroxamsäure
KR101968370B1 (ko) * 2011-12-28 2019-04-11 갈렉틴 테라퓨틱스, 인크. 인간 질환의 치료를 위한 신규 탄수화물 약물의 조성물
EP2907512A1 (en) 2014-02-14 2015-08-19 Commissariat A L'energie Atomique Et Aux Energies Alternatives Inhibitors of MMP-12 as antiviral Agents
CN105728047B (zh) * 2016-03-24 2017-12-26 万华化学集团股份有限公司 一种氢甲酰化催化剂及其制备方法和应用
JP2017210442A (ja) * 2016-05-26 2017-11-30 イノレックス インベストメント コーポレイション マトリックスメタロプロテイナーゼを阻害して皮膚の老化を軽減する方法及び関連の相乗的組成物
IT201600083975A1 (it) * 2016-08-09 2018-02-09 Consorzio Interuniversitario Naz Per La Scienza E Tecnologia Dei Materiali Acido ialuronico funzionalizzato
JP6541118B1 (ja) * 2018-04-27 2019-07-10 株式会社成和化成 化粧品基材および該化粧品基材を含有する毛髪用化粧品、美白剤
LV15485B (lv) * 2018-09-13 2020-06-20 Latvijas Organiskās Sintēzes Institūts Selenofēnhromenonu hidroksāmskābes, to izgatavošana un izmantošana angioģenēzes inhibīcijā

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LU68901A1 (xx) 1973-11-30 1975-08-20
US5506242A (en) * 1993-01-06 1996-04-09 Ciba-Geigy Corporation Arylsufonamido-substituted hydroxamic acids
US5455258A (en) 1993-01-06 1995-10-03 Ciba-Geigy Corporation Arylsulfonamido-substituted hydroxamic acids
JP3628335B2 (ja) * 1996-01-23 2005-03-09 塩野義製薬株式会社 スルホン化されたアミノ酸誘導体およびそれを含有するメタロプロティナーゼ阻害剤
WO1997045402A1 (fr) * 1996-05-24 1997-12-04 Ono Pharmaceutical Co., Ltd. Derives de phenylsulfonamide
CA2268418A1 (en) * 1996-10-22 1998-04-30 Pharmacia & Upjohn Company .alpha.-amino sulfonyl hydroxamic acids as matrix metalloproteinase inhibitors
US6303636B1 (en) * 1997-02-03 2001-10-16 Pfizer Inc Arylsulfonylamino hydroxamic acid derivatives
AU7294098A (en) * 1997-05-09 1998-11-27 Agouron Pharmaceuticals, Inc. Metalloproteinase inhibitors, pharmaceutical compositions containing them and their pharmaceutical uses
IL134273A0 (en) * 1997-07-31 2001-04-30 Procter & Gamble Acyclic metalloprotease inhibitors
JPH11199512A (ja) 1997-10-24 1999-07-27 Pfizer Prod Inc 変形性関節症および他のｍｍｐ媒介疾患の治療のためのｍｍｐ−１３選択的阻害剤の使用
PA8469601A1 (es) * 1998-04-10 2000-09-29 Pfizer Prod Inc Procedimiento para alquilar sulfonamidas impedidas estericamente
PL349449A1 (en) * 1998-12-22 2002-07-29 Hoffmann La Roche Sulfonamide hydroxamates
JP2002533375A (ja) 1998-12-28 2002-10-08 セラニーズ ベンチャーズ ゲー・エム・ベー・ハー 水不溶性線状ポリ−α−グルカンのＵＶフィルターとしての使用
FR2799964B1 (fr) 1999-10-22 2002-07-26 Oreal Emulsions contenant au moins un filtre uv organique insoluble et un polymere associatif
ES2264985T3 (es) 2000-05-10 2007-02-01 Ciba Specialty Chemicals Holding Inc. Compuestos sililados como precursores para composiciones de autobronceado.
GB0028161D0 (en) 2000-11-17 2001-01-03 Natural Environment Res Personal care compositions
FR2827860B1 (fr) * 2001-07-24 2004-12-10 Servier Lab Nouveau procede de synthese de derives de l'acide (2s, 3as, 7as)-1-[(s)-alanyl]-octahydro-1h-indole-2-carboxyline et application a la synthese du perindopril
DE10155200A1 (de) 2001-11-12 2003-05-28 Skinlab Gmbh Verwendung von Cholesterin, cholesterinhaltigen Substanzen oder von den Cholesteringehalt erhöhenden Substanzen in kosmetischen und dermatologischen Zubereitungen zum Zwecke der UV-Protektion
DE10155769A1 (de) 2001-11-14 2003-05-22 Cognis Deutschland Gmbh Kosmetische und/oder pharmazeutische Emulsionen
IL165259A0 (en) * 2002-05-29 2005-12-18 Merck & Co Inc Compounds useful in the treatment of anthraxa and inhibiting lethal factor

Also Published As

Publication number Publication date
JP2008509108A (ja) 2008-03-27
WO2006013193A2 (en) 2006-02-09
BRPI0514030A (pt) 2008-05-27
CA2580235A1 (en) 2006-02-09
MX2007001269A (es) 2007-07-16
US7772430B2 (en) 2010-08-10
RU2406721C2 (ru) 2010-12-20
WO2006013193A8 (en) 2010-07-29
WO2006013193A3 (en) 2006-08-31
ATE492530T1 (de) 2011-01-15
AU2005268765B2 (en) 2011-08-04
RU2007107872A (ru) 2008-09-10
US20080249032A1 (en) 2008-10-09
RU2010136061A (ru) 2012-03-10
DE602005025495D1 (de) 2011-02-03
EP1781601B1 (en) 2010-12-22
AU2005268765A1 (en) 2006-02-09
US20100298439A1 (en) 2010-11-25
EP2308837A3 (en) 2011-04-20
EP2308837A2 (en) 2011-04-13
ITFI20040174A1 (it) 2004-11-03
EP1781601A2 (en) 2007-05-09
CN101076514A (zh) 2007-11-21

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