IS6766A - Pravastatínnatríum, að mestu leyti laust við pravastatínlaktón og epí-pravastatín, og blöndur sem innihalda það - Google Patents

Pravastatínnatríum, að mestu leyti laust við pravastatínlaktón og epí-pravastatín, og blöndur sem innihalda það

Info

Publication number: IS6766A
Authority: IS; Iceland
Prior art keywords: pravastatin; epi; lactone; mixtures containing; largely free
Prior art date: 2000-10-05

Application number

IS6766A

Other languages

English (en)

Icelandic (is)

Inventor

Keri Vilmos

Deak Lajos

Forgacs Ilona

Szabo Csaba

Edit Nagyne Arvai

Original Assignee

Teva Gyogyszergy βr Részvényt βrsas βg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-05

Filing date

2003-04-01

Publication date

2003-04-01

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22897222&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS6766(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2003-04-01 Application filed by Teva Gyogyszergy βr Részvényt βrsas βg filed Critical Teva Gyogyszergy βr Részvényt βrsas βg

2003-04-01 Publication of IS6766A publication Critical patent/IS6766A/is

Links

239000000203 mixture Substances 0.000 title 1
229960002965 pravastatin Drugs 0.000 title 1
TUZYXOIXSAXUGO-PZAWKZKUSA-N pravastatin Chemical compound C1=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@H]2[C@@H](OC(=O)[C@@H](C)CC)C[C@H](O)C=C21 TUZYXOIXSAXUGO-PZAWKZKUSA-N 0.000 title 1
OQARDMYXSOFTLN-PZAWKZKUSA-N pravastatin lactone Chemical compound C([C@H]1[C@@H](C)C=CC2=C[C@@H](O)C[C@@H]([C@H]12)OC(=O)[C@@H](C)CC)C[C@@H]1C[C@@H](O)CC(=O)O1 OQARDMYXSOFTLN-PZAWKZKUSA-N 0.000 title 1
229960001495 pravastatin sodium Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
- C07F1/04—Sodium compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/48—Separation; Purification; Stabilisation; Use of additives
- C07C67/52—Separation; Purification; Stabilisation; Use of additives by change in the physical state, e.g. crystallisation

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Heart & Thoracic Surgery (AREA)
Epidemiology (AREA)
Cardiology (AREA)
Crystallography & Structural Chemistry (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Emergency Medicine (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrane Compounds (AREA)

IS6766A 2000-10-05 2003-04-01 Pravastatínnatríum, að mestu leyti laust við pravastatínlaktón og epí-pravastatín, og blöndur sem innihalda það IS6766A (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US23827800P	2000-10-05	2000-10-05
PCT/US2001/031230 WO2002030415A1 (en)	2000-10-05	2001-10-05	Pravastatin sodium substantially free of pravastatin lactone and epi-pravastatin, and compositions containing same

Publications (1)

Publication Number	Publication Date
IS6766A true IS6766A (is)	2003-04-01

Family

ID=22897222

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS6766A IS6766A (is)	2000-10-05	2003-04-01	Pravastatínnatríum, að mestu leyti laust við pravastatínlaktón og epí-pravastatín, og blöndur sem innihalda það

Country Status (18)

Country	Link
EP (1)	EP1330245A4 (ja)
JP (6)	JP3737801B2 (ja)
KR (1)	KR20030059173A (ja)
CN (1)	CN1468098A (ja)
AU (1)	AU2002211462A1 (ja)
CA (1)	CA2422744A1 (ja)
CZ (1)	CZ20031166A3 (ja)
HR (1)	HRP20030347A2 (ja)
HU (1)	HUP0400913A2 (ja)
IL (1)	IL155194A0 (ja)
IS (1)	IS6766A (ja)
MX (1)	MXPA03002963A (ja)
NO (1)	NO20031532L (ja)
NZ (1)	NZ525631A (ja)
PL (1)	PL361230A1 (ja)
SK (1)	SK5232003A3 (ja)
WO (1)	WO2002030415A1 (ja)
ZA (1)	ZA200302313B (ja)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1481674B1 (en) *	1999-11-30	2008-01-02	TEVA Gyógyszergyár Zártkörüen Müködö Részvénytársaság	Process for recovering statin compounds from a fermentation broth
RU2002114072A (ru) *	1999-11-30	2004-07-20	Биогал Джиоджисзерджиар РТ (HU)	Способ выделения соединений статина из ферментационного бульона
EP1798214A3 (en) *	1999-11-30	2007-08-01	Teva Gyogyszergyár Zártköruen Muködo Részvenytarsaság	Process for recovering statin compounds from a fermentation broth
CA2394200C (en)	1999-12-14	2006-10-03	Biogal Gyogyszergyar Rt.	Novel forms of pravastatin sodium
CZ20031166A3 (cs) *	2000-10-05	2004-04-14	Biogal Gyogyszergyar Rt	Sodná sůl pravastatinu, která v podstatě neobsahuje pravastatin lakton a epi-pravastatin a kompozice na její bázi
JP3236282B1 (ja) *	2000-10-16	2001-12-10	三共株式会社	プラバスタチンを精製する方法
GB0218781D0 (en)	2002-08-13	2002-09-18	Astrazeneca Ab	Chemical process
EP1452519A1 (en) *	2003-02-25	2004-09-01	Balkanpharma-Razgrad AD	Method for the isolation and purification of pravastatin sodium
GB0312896D0 (en)	2003-06-05	2003-07-09	Astrazeneca Ab	Chemical process
UY28501A1 (es)	2003-09-10	2005-04-29	Astrazeneca Uk Ltd	Compuestos químicos
GB0324791D0 (en)	2003-10-24	2003-11-26	Astrazeneca Ab	Chemical process
PT1641447E (pt)	2003-11-24	2008-12-10	Teva Gyogyszergyar Zartkoeruee	Método de purificação da pravastatina
EP1786414A4 (en)	2004-08-06	2008-04-09	Transform Pharmaceuticals Inc	NEW PHARMACEUTICAL STATIN COMPOSITIONS AND RELEVANT TREATMENT PROCEDURES
ES2254028B1 (es) *	2004-11-29	2007-03-01	Ercros Industrial, S.A.	Procedimiento para la obtencion de pravastatina sodica purificada.
JP2008527012A (ja) *	2005-02-25	2008-07-24	テバファーマシューティカルインダストリーズリミティド	タダラフィルの精製法
JP4813841B2 (ja) *	2005-07-25	2011-11-09	キユーピー株式会社	プラバスタチンナトリウムの製造方法
HU229260B1 (en) *	2010-11-29	2013-10-28	Egis Gyogyszergyar Nyrt	Process for preparation of rosuvastatin salts
CN114031496A (zh) *	2021-11-30	2022-02-11	广东蓝宝制药有限公司	一种高纯度普伐他汀1,1,3,3-四甲基丁胺的制备方法

Family Cites Families (25)

* Cited by examiner, † Cited by third party
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US3378441A (en) *	1963-10-17	1968-04-16	S B Penick & Company	Tetraene antibiotic purification
JPS5221594B2 (ja) *	1973-09-29	1977-06-11
YU40452B (en) *	1975-02-07	1986-02-28	Beecham Group Plc	Process for the elimination of contaminating impurities from clavulinic acid
US4231938A (en) *	1979-06-15	1980-11-04	Merck & Co., Inc.	Hypocholesteremic fermentation products and process of preparation
JPS572240A (en) *	1980-06-06	1982-01-07	Sankyo Co Ltd	Ml-236b derivative
DK149080C (da) *	1980-06-06	1986-07-28	Sankyo Co	Fremgangsmaade til fremstilling af derivater af ml-236b-carboxylsyre
JPS5889191A (ja) *	1981-11-20	1983-05-27	Sankyo Co Ltd	３−ヒドロキシ−ｍｌ−２３６ｂ誘導体の製造法
JPS5890509A (ja) *	1981-11-25	1983-05-30	Sankyo Co Ltd	高コレステロ−ル血症治療用組成物
JPH01190661A (ja) *	1988-01-22	1989-07-31	Konishi Kagaku Kogyo Kk	４，４′−ジヒドロキシジフエニルスルホンの精製法
JP2739328B2 (ja) *	1988-09-14	1998-04-15	日本ケミファ株式会社	ベンズイミダゾール化合物の精製方法
US5202029A (en) *	1991-03-13	1993-04-13	Caron Kabushiki Kaisha	Process for purification of hmg-coa reductase inhibitors
NZ250609A (en) *	1992-12-28	1995-07-26	Sankyo Co	Hexahydronaphthalene esters and ring closed lactones; preparation and medicaments
JPH06256278A (ja) *	1993-03-03	1994-09-13	Nissan Chem Ind Ltd	光学活性α−カルバモイルアルカン酸誘導体およびその製法
CA2126365C (en) *	1993-07-06	1999-08-24	Steven W. Felman	Recovery of citric acid from impure process streams by addition of strong acids and salts thereof
EP0754239B1 (en) *	1994-03-31	1997-10-08	Cultor Ltd.	Process for natamycin recovery
ATE189804T1 (de) *	1995-08-03	2000-03-15	Dsm Nv	Selektives verfahren zur deacylierung von acylverbindungen
JPH09124655A (ja) *	1995-11-01	1997-05-13	Sankyo Co Ltd	新規スクアレンシンターゼ阻害活性化合物
EP0877089A1 (en) *	1997-05-07	1998-11-11	Gist-Brocades B.V.	HMG-CoA reductase inhibitor preparation process
SI20070A (sl) *	1998-09-18	2000-04-30	LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d.	Nove soli inhibitorjev HMG-CoA reduktaze
SI20072A (sl) *	1998-09-18	2000-04-30	LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d.	Postopek za pridobivanje inhibitorjev HMG-CoA reduktaze
JP2000229855A (ja) *	1998-12-07	2000-08-22	Satoshi Takebe	プラバスタチンナトリウム錠
WO2000046175A1 (en) *	1999-02-03	2000-08-10	Institute For Drug Research Ltd.	Microbial process for preparing pravastatin
HUP9902352A1 (hu) *	1999-07-12	2000-09-28	Gyógyszerkutató Intézet Kft.	Eljárás pravasztatin mikrobiológiai előállítására
RU2002114072A (ru) *	1999-11-30	2004-07-20	Биогал Джиоджисзерджиар РТ (HU)	Способ выделения соединений статина из ферментационного бульона
CZ20031166A3 (cs) *	2000-10-05	2004-04-14	Biogal Gyogyszergyar Rt	Sodná sůl pravastatinu, která v podstatě neobsahuje pravastatin lakton a epi-pravastatin a kompozice na její bázi

2001
- 2001-10-05 CZ CZ20031166A patent/CZ20031166A3/cs unknown
- 2001-10-05 WO PCT/US2001/031230 patent/WO2002030415A1/en not_active Application Discontinuation
- 2001-10-05 IL IL15519401A patent/IL155194A0/xx unknown
- 2001-10-05 KR KR10-2003-7004764A patent/KR20030059173A/ko not_active IP Right Cessation
- 2001-10-05 CN CNA018168604A patent/CN1468098A/zh active Pending
- 2001-10-05 EP EP01979511A patent/EP1330245A4/en not_active Withdrawn
- 2001-10-05 AU AU2002211462A patent/AU2002211462A1/en not_active Abandoned
- 2001-10-05 CA CA002422744A patent/CA2422744A1/en not_active Abandoned
- 2001-10-05 JP JP2002533858A patent/JP3737801B2/ja not_active Expired - Fee Related
- 2001-10-05 PL PL01361230A patent/PL361230A1/xx unknown
- 2001-10-05 HU HU0400913A patent/HUP0400913A2/hu not_active IP Right Cessation
- 2001-10-05 NZ NZ525631A patent/NZ525631A/en unknown
- 2001-10-05 SK SK523-2003A patent/SK5232003A3/sk unknown
- 2001-10-05 MX MXPA03002963A patent/MXPA03002963A/es not_active Application Discontinuation
2003
- 2003-03-25 ZA ZA200302313A patent/ZA200302313B/en unknown
- 2003-04-01 IS IS6766A patent/IS6766A/is unknown
- 2003-04-04 NO NO20031532A patent/NO20031532L/no not_active Application Discontinuation
- 2003-05-02 HR HR20030347A patent/HRP20030347A2/xx not_active Application Discontinuation
2004
- 2004-09-24 JP JP2004278522A patent/JP2005013238A/ja not_active Withdrawn
2005
- 2005-08-18 JP JP2005237299A patent/JP2006036781A/ja active Pending
2009
- 2009-08-21 JP JP2009191951A patent/JP2009268479A/ja not_active Withdrawn
2013
- 2013-01-25 JP JP2013011711A patent/JP2013128486A/ja not_active Withdrawn
2015
- 2015-07-31 JP JP2015152088A patent/JP2015212300A/ja active Pending

Also Published As

Publication number	Publication date
IL155194A0 (en)	2003-11-23
SK5232003A3 (en)	2004-06-08
WO2002030415A9 (en)	2002-10-31
PL361230A1 (en)	2004-10-04
HUP0400913A2 (en)	2006-11-28
HRP20030347A2 (en)	2005-04-30
NO20031532D0 (no)	2003-04-04
CA2422744A1 (en)	2002-04-18
ZA200302313B (en)	2004-03-25
EP1330245A1 (en)	2003-07-30
KR20030059173A (ko)	2003-07-07
WO2002030415A1 (en)	2002-04-18
CZ20031166A3 (cs)	2004-04-14
AU2002211462A1 (en)	2002-04-22
EP1330245A4 (en)	2004-10-20
JP2006036781A (ja)	2006-02-09
JP2013128486A (ja)	2013-07-04
JP3737801B2 (ja)	2006-01-25
MXPA03002963A (es)	2005-01-25
CN1468098A (zh)	2004-01-14
JP2005013238A (ja)	2005-01-20
NO20031532L (no)	2003-04-04
NZ525631A (en)	2005-05-27
JP2004510817A (ja)	2004-04-08
JP2015212300A (ja)	2015-11-26
JP2009268479A (ja)	2009-11-19

Publication	Publication Date	Title
IS6766A (is)	2003-04-01	Pravastatínnatríum, að mestu leyti laust við pravastatínlaktón og epí-pravastatín, og blöndur sem innihalda það
DK1329456T3 (da)	2006-12-04	Glucopyranosyloxybenzylbenzenderivater og medicinske sammensætninger indeholdende samme
ITMI20011489A0 (it)	2001-07-12	Miscele stabilizzanti
NO20024355D0 (no)	2002-09-12	Nukleosidforbindelser og anvendelser derav
ID30590A (id)	2002-01-03	Celana sekali pakai jenis-celana pendek
ID30187A (id)	2001-11-15	Dongkrak jenis pantagraf
PT1250321E (pt)	2006-09-29	Composicao de gliburida
NO20011026D0 (no)	2001-02-28	Matvare og fremgangsmÕte for fremstilling derav
ATE275938T1 (de)	2004-10-15	Stabiles und wirksames weiches feststoffprodukt
IS6698A (is)	2003-01-24	Háhreinsaðar símvastatínblöndur
IS6021A (is)	2001-10-20	Lyfjasamsetningar sem innihalda sítalópram
ATE272046T1 (de)	2004-08-15	O-substituierte 6-methyl-tramadol-derivate
AR028070A1 (es)	2003-04-23	Sintesis de compuestos de ciclohexendimetanol o ciclohexandimetanol
NO20024354D0 (no)	2002-09-12	N-deacetyltiocolchicin-derivater og farmasöytiske sammensetninger inneholdende dem
NO20025474L (no)	2003-01-07	Benzofuranderivater
NO20011703D0 (no)	2001-04-04	Kondensator av ikke-brennbar og uhellsforhindrende type
IS6857A (is)	2003-06-23	Lyfjafræðileg samsetning sem innheldur sítalópram
GB2358859B (en)	2003-10-15	Synthesis of isosorbide-5-mononitrate and substituted analogues thereof
DE60124221D1 (de)	2006-12-14	MONOHYDRAT DES CIS-LITHIUM-CYANO-4-i3-(CYCLOPENTYLOY)-4-METHOXYPHENYLöCYCLOHEXANCARBOXYLATS
FI20000526A0 (fi)	2000-03-08	Preassurans-sammutusjärjestelmä
FR2809403B1 (fr)	2002-08-23	Bacteriocine anti-listeria
FI4458U1 (fi)	2000-06-02	Savusauna
FR2810531B1 (fr)	2003-05-23	Trocart de coelio-chirurgie
SE0004003D0 (sv)	2000-11-02	Synthesis of FLG
FI4637U1 (fi)	2000-09-29	Parannettu savusauna