IL74681A - Cyclosporins,their production and pharmaceutical compositions containing them - Google Patents

Cyclosporins,their production and pharmaceutical compositions containing them

Info

Publication number: IL74681A
Authority: IL; Israel
Prior art keywords: cyclosporins; production; pharmaceutical compositions; compositions containing; pharmaceutical
Prior art date: 1984-03-23

Application number

IL74681A

Other languages

English (en)

Other versions

IL74681A0 (en

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-03-23

Filing date

1985-03-21

Publication date

1989-09-10

1984-03-23 Priority claimed from GB848407618A external-priority patent/GB8407618D0/en

1984-05-10 Priority claimed from GB848411922A external-priority patent/GB8411922D0/en

1985-03-21 Application filed by Sandoz Ag filed Critical Sandoz Ag

1985-06-30 Publication of IL74681A0 publication Critical patent/IL74681A0/xx

1989-09-10 Publication of IL74681A publication Critical patent/IL74681A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/19—Antibiotic
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/27—Cyclic peptide or cyclic protein

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Immunology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Transplantation (AREA)
Rheumatology (AREA)
Oncology (AREA)
Pain & Pain Management (AREA)
Tropical Medicine & Parasitology (AREA)
Communicable Diseases (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

IL74681A 1984-03-23 1985-03-21 Cyclosporins,their production and pharmaceutical compositions containing them IL74681A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB848407618A GB8407618D0 (en)	1984-03-23	1984-03-23	Organic compounds
GB848411922A GB8411922D0 (en)	1984-05-10	1984-05-10	Organic compounds

Publications (2)

Publication Number	Publication Date
IL74681A0 IL74681A0 (en)	1985-06-30
IL74681A true IL74681A (en)	1989-09-10

Family

ID=26287502

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL74681A IL74681A (en)	1984-03-23	1985-03-21	Cyclosporins,their production and pharmaceutical compositions containing them

Country Status (24)

Country	Link
US (1)	US4639434A (sv)
JP (1)	JPH08838B2 (sv)
AT (1)	AT388737B (sv)
BE (1)	BE901980A (sv)
CA (1)	CA1247546A (sv)
CH (1)	CH667274A5 (sv)
CS (1)	CS249542B2 (sv)
DE (1)	DE3509809A1 (sv)
DK (1)	DK128285A (sv)
ES (1)	ES8702926A1 (sv)
FI (1)	FI851120L (sv)
FR (1)	FR2561651B1 (sv)
GB (1)	GB2155936B (sv)
GR (1)	GR850716B (sv)
HU (1)	HU200786B (sv)
IL (1)	IL74681A (sv)
IT (1)	IT1199962B (sv)
LU (1)	LU85819A1 (sv)
NL (1)	NL8500828A (sv)
NO (1)	NO851160L (sv)
NZ (1)	NZ211526A (sv)
PH (2)	PH23357A (sv)
PT (1)	PT80149B (sv)
SE (1)	SE461334B (sv)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE92501T1 (de)	1984-10-04	1993-08-15	Sandoz Ag	Monoklonale antikoerper gegen zyklosporine.
US4798823A (en) *	1987-06-03	1989-01-17	Merck & Co., Inc.	New cyclosporin analogs with modified "C-9 amino acids"
EP0296122B1 (en) *	1987-06-17	1993-09-29	Sandoz Ag	Cyclosporins and their use as pharmaceuticals
DE3888357T2 (de) *	1987-06-22	1994-09-15	Merck & Co Inc	Cyclosporin-Derivate, die eine modifizierte Aminosäure auf Stellung 8 tragen.
US5227467A (en) *	1987-08-03	1993-07-13	Merck & Co., Inc.	Immunosuppressive fluorinated cyclosporin analogs
EP0391909B1 (en) *	1987-09-03	1994-08-17	The University Of Georgia Research Foundation, Inc.	Ocular cyclosporin composition
US4839342A (en) *	1987-09-03	1989-06-13	University Of Georgia Research Foundation, Inc.	Method of increasing tear production by topical administration of cyclosporin
US5089390A (en) *	1987-09-04	1992-02-18	Syntex (U.S.A.) Inc.	2-methyl-4-hexene- and 2-methyl-4-heptene-1,2-diol derivatives
US5236899A (en) *	1987-11-16	1993-08-17	Merck & Co., Inc.	6-position cyclosporin a analogs as modifiers of cytotoxic drug resistance
US4914188A (en) *	1987-11-16	1990-04-03	Merck & Co., Inc.	Novel 6-position cyclosporin analogs as non-immunosuppressive antagonists of cyclosporin binding to cyclophilin
CH679119A5 (sv) *	1988-05-13	1991-12-31	Sandoz Ag
US4996193A (en) *	1989-03-03	1991-02-26	The Regents Of The University Of California	Combined topical and systemic method of administration of cyclosporine
US5540931A (en) *	1989-03-03	1996-07-30	Charles W. Hewitt	Methods for inducing site-specific immunosuppression and compositions of site specific immunosuppressants
GB8916901D0 (en)	1989-07-24	1989-09-06	Sandoz Ltd	Improvements in or relating to organic compounds
US5122511A (en) *	1990-02-27	1992-06-16	Merck & Co., Inc.	Immunosuppressive cyclosporin analogs with modified amino acids at position-8
US5202310A (en) *	1990-06-06	1993-04-13	Levy Gary A	Cyclosporine metabolites
CZ280909B6 (cs) *	1990-11-02	1996-05-15	Novartis Ag	Nové cyklosporiny
DE69133095T2 (de)	1990-11-20	2003-03-27	Dade Behring Marburg Gmbh	Cyclosporin-Immunoassay
US5747330A (en) *	1996-06-05	1998-05-05	Poli Industria Chimica	Antibiotic producing microbe
EP0991660B8 (en)	1997-10-08	2006-04-05	Isotechnika,Inc.	DEUTERATED and undeuterated CYCLOSPORINE ANALOGS AND THEIR USE AS IMMUNOMODULATING AGENTS
US20030220234A1 (en) *	1998-11-02	2003-11-27	Selvaraj Naicker	Deuterated cyclosporine analogs and their use as immunodulating agents
US5990274A (en) *	1997-11-25	1999-11-23	Dade Behring Inc.	Cyclosporine derivatives and uses thereof
US7449544B2 (en) *	1999-11-30	2008-11-11	Cyclacel Limited	p21 peptides
PT1436321E (pt)	2001-10-19	2006-10-31	Isotechnika Inc	Sintese de analogos de ciclosporina
KR100978836B1 (ko) *	2001-10-19	2010-08-30	이소테크니카 인코포레이티드	신규한 시클로스포린 유사체 미세유화액 예비농축물
AU2004222306A1 (en) *	2003-03-17	2004-09-30	Albany Molecular Research, Inc.	Novel cyclosporins
WO2006039163A2 (en) *	2004-09-29	2006-04-13	Amr Technology, Inc.	Cyclosporin alkyne analogues and their pharmaceutical uses
US7511013B2 (en) *	2004-09-29	2009-03-31	Amr Technology, Inc.	Cyclosporin analogues and their pharmaceutical uses
EP1812037A4 (en) *	2004-10-06	2009-11-11	Amr Technology Inc	ALKYNES OF CYCLOSPORINE AND THEIR USEFUL AS PHARMACEUTICAL AGENTS
US7696165B2 (en) *	2006-03-28	2010-04-13	Albany Molecular Research, Inc.	Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders
US7696166B2 (en) *	2006-03-28	2010-04-13	Albany Molecular Research, Inc.	Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders
US7576057B2 (en)	2006-11-20	2009-08-18	Scynexis, Inc.	Cyclic peptides
JP6144627B2 (ja)	2010-12-15	2017-06-07	コントラヴィアファーマシューティカルズ、インク．	アミノ酸１および３で修飾されたシクロスポリン類似体分子
CA2852056C (en)	2011-03-11	2021-08-10	Beth Israel Deaconess Medical Center, Inc.	Anti-cd40 antibodies and uses thereof
CN104877013B (zh) *	2015-06-03	2018-04-20	兰州大学	环孢菌素t及其制备方法和应用
PT3307322T (pt)	2015-09-04	2021-04-23	Primatope Therapeutics Inc	Anticorpos anti-cp40 humanizados e as suas utilizações referência cruzada relativa às aplicações associadas

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS57140753A (en) *	1981-01-09	1982-08-31	Sandoz Ag	Novel cyclosporine
US4384996A (en) *	1981-01-09	1983-05-24	Sandoz Ltd.	Novel cyclosporins

1985
- 1985-03-18 CH CH1194/85A patent/CH667274A5/de not_active IP Right Cessation
- 1985-03-19 DE DE19853509809 patent/DE3509809A1/de not_active Ceased
- 1985-03-19 US US06/713,429 patent/US4639434A/en not_active Expired - Fee Related
- 1985-03-19 FR FR858504172A patent/FR2561651B1/fr not_active Expired - Lifetime
- 1985-03-20 FI FI851120A patent/FI851120L/fi not_active Application Discontinuation
- 1985-03-20 GB GB08507270A patent/GB2155936B/en not_active Expired
- 1985-03-20 PH PH32014A patent/PH23357A/en unknown
- 1985-03-20 PH PH32013A patent/PH21868A/en unknown
- 1985-03-21 BE BE1/011217A patent/BE901980A/fr not_active IP Right Cessation
- 1985-03-21 HU HU851045A patent/HU200786B/hu not_active IP Right Cessation
- 1985-03-21 PT PT80149A patent/PT80149B/pt not_active IP Right Cessation
- 1985-03-21 SE SE8501392A patent/SE461334B/sv not_active IP Right Cessation
- 1985-03-21 NL NL8500828A patent/NL8500828A/nl not_active Application Discontinuation
- 1985-03-21 CA CA000477127A patent/CA1247546A/en not_active Expired
- 1985-03-21 LU LU85819A patent/LU85819A1/fr unknown
- 1985-03-21 NZ NZ211526A patent/NZ211526A/xx unknown
- 1985-03-21 DK DK128285A patent/DK128285A/da not_active Application Discontinuation
- 1985-03-21 GR GR850716A patent/GR850716B/el unknown
- 1985-03-21 IL IL74681A patent/IL74681A/xx unknown
- 1985-03-21 ES ES541465A patent/ES8702926A1/es not_active Expired
- 1985-03-22 NO NO851160A patent/NO851160L/no unknown
- 1985-03-22 JP JP60059339A patent/JPH08838B2/ja not_active Expired - Lifetime
- 1985-03-22 AT AT0086385A patent/AT388737B/de not_active IP Right Cessation
- 1985-03-22 IT IT47852/85A patent/IT1199962B/it active
- 1985-03-23 CS CS852132A patent/CS249542B2/cs unknown

Also Published As

Publication number	Publication date
DE3509809A1 (de)	1986-01-09
IT1199962B (it)	1989-01-05
PH23357A (en)	1989-07-14
IT8547852A1 (it)	1986-09-22
GB8507270D0 (en)	1985-04-24
NO851160L (no)	1985-09-24
JPH08838B2 (ja)	1996-01-10
FR2561651A1 (fr)	1985-09-27
AT388737B (de)	1989-08-25
GB2155936A (en)	1985-10-02
NZ211526A (en)	1988-08-30
IL74681A0 (en)	1985-06-30
US4639434A (en)	1987-01-27
ES8702926A1 (es)	1987-01-16
DK128285A (da)	1985-09-24
NL8500828A (nl)	1985-10-16
PH21868A (en)	1988-03-25
SE8501392D0 (sv)	1985-03-21
PT80149B (en)	1987-03-23
ES541465A0 (es)	1987-01-16
ATA86385A (de)	1989-01-15
CA1247546A (en)	1988-12-28
HUT38370A (en)	1986-05-28
SE8501392L (sv)	1985-09-24
BE901980A (fr)	1985-09-23
FR2561651B1 (fr)	1990-03-09
GB2155936B (en)	1987-09-16
CS249542B2 (en)	1987-03-12
PT80149A (en)	1985-04-01
LU85819A1 (fr)	1985-12-12
DK128285D0 (da)	1985-03-21
HU200786B (en)	1990-08-28
JPS60215700A (ja)	1985-10-29
GR850716B (sv)	1985-07-19
CH667274A5 (de)	1988-09-30
FI851120L (fi)	1985-09-24
SE461334B (sv)	1990-02-05
FI851120A0 (fi)	1985-03-20
IT8547852A0 (it)	1985-03-22

Publication	Publication Date	Title
IL74681A0 (en)	1985-06-30	Cyclosporins,their production and pharmaceutical compositions containing them
IL77004A0 (en)	1986-04-29	5-amino-4-hydroxyvaleryl derivatives,their manufacture and pharmaceutical compositions containing them
IL65167A0 (en)	1982-05-31	N-acyl-polypeptides,their production and pharmaceutical compositions containing them
IL84765A0 (en)	1988-05-31	Pyridazodiazepine derivatives,their manufacture and pharmaceutical compositions containing them
IL89752A0 (en)	1989-09-28	Bisphosphonates,their production and pharmaceutical compositions containing them
IL74043A0 (en)	1985-04-30	8alpha-acylaminoergolines,their production and pharmaceutical compositions containing them
IL88927A0 (en)	1989-08-15	Thienoazepines,their production and pharmaceutical compositions containing them
IL72219A0 (en)	1984-10-31	Peptides,their production and pharmaceutical compositions containing them
IL68576A0 (en)	1983-09-30	Azepinoindoles,their production and pharmaceutical compositions containing them
IL85722A0 (en)	1988-08-31	Propiolophenone derivatives,their manufacture and pharmaceutical compositions containing them
IL75966A0 (en)	1985-12-31	3-substituted-1-aminoalkyl-1h-indoles,their preparation and pharmaceutical compositions containing them
IL76823A0 (en)	1986-02-28	1,2,4-triazolo-carbamates,their preparation and pharmaceutical compositions containing them
IL81355A0 (en)	1987-08-31	8alpha-acylaminoergolines,their production and pharmaceutical compositions containing them
NZ214088A (en)	1988-09-29	1,3-diazoles and pharmaceutical compositions
DE3573784D1 (en)	1989-11-23	Carboxyalkyldipeptides, their preparation and pharmaceutical compositions containing them
IL75636A0 (en)	1985-10-31	Cephalosporins,their preparation and pharmaceutical compositions containing them
IL82965A0 (en)	1987-12-20	Benzimidazoles,their production and pharmaceutical compositions containing them
GB2169291B (en)	1988-09-21	8a-acylaminoergolines, their production and pharmaceutical compositions containing them
IL75814A0 (en)	1985-11-29	Dihydropyridines,their production and pharmaceutical compositions containing them
IL67813A0 (en)	1983-06-15	Benzothienylallylamines,their production and pharmaceutical compositions containing them
IL75468A0 (en)	1985-10-31	Naphthoxazines,their production and pharmaceutical compositions containing them
IL67715A0 (en)	1983-05-15	3,3-dialkyl-and 3,3-alkylene-indoline derivatives,their production and pharmaceutical compositions containing them
IL74042A0 (en)	1985-04-30	N-(naphthyl-alkyl)-hydroxylamines,their production and pharmaceutical compositions containing them
ZA851373B (en)	1986-09-24	Diazepinoindoles,their production and pharmaceutical compositions containing them
IL84366A0 (en)	1988-04-29	2,6-diamino-3-halogenbenzylpyridines,their manufacture and pharmaceutical compositions containing them