IL101903A - Topical preparations containing terbinafine - Google Patents
Topical preparations containing terbinafineInfo
- Publication number
- IL101903A IL101903A IL10190392A IL10190392A IL101903A IL 101903 A IL101903 A IL 101903A IL 10190392 A IL10190392 A IL 10190392A IL 10190392 A IL10190392 A IL 10190392A IL 101903 A IL101903 A IL 101903A
- Authority
- IL
- Israel
- Prior art keywords
- compound
- composition
- composition according
- formula
- oil phase
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Inorganic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Lubricants (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919110884A GB9110884D0 (en) | 1991-05-20 | 1991-05-20 | Pharmaceutical compositions |
GB919111477A GB9111477D0 (en) | 1991-05-29 | 1991-05-29 | Pharmaceutical composition |
Publications (2)
Publication Number | Publication Date |
---|---|
IL101903A0 IL101903A0 (en) | 1992-12-30 |
IL101903A true IL101903A (en) | 1998-08-16 |
Family
ID=26298929
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL10190392A IL101903A (en) | 1991-05-20 | 1992-05-18 | Topical preparations containing terbinafine |
Country Status (29)
Country | Link |
---|---|
US (2) | US5681849A (ko) |
EP (1) | EP0515310B1 (ko) |
JP (1) | JP2651311B2 (ko) |
KR (1) | KR100303095B1 (ko) |
AT (1) | AT400517B (ko) |
AU (1) | AU647922B2 (ko) |
CA (1) | CA2068957C (ko) |
CH (1) | CH683823A5 (ko) |
CY (1) | CY1942A (ko) |
CZ (2) | CZ285275B6 (ko) |
DE (1) | DE4215450B4 (ko) |
DK (1) | DK0515310T3 (ko) |
ES (1) | ES2186668T3 (ko) |
FI (2) | FI102458B (ko) |
FR (1) | FR2676646B1 (ko) |
GB (1) | GB2255908B (ko) |
HK (1) | HK148896A (ko) |
HU (1) | HU223343B1 (ko) |
IE (1) | IE70913B1 (ko) |
IL (1) | IL101903A (ko) |
IT (1) | IT1260710B (ko) |
LU (1) | LU88114A1 (ko) |
MX (1) | MX9202328A (ko) |
NO (1) | NO180772C (ko) |
PT (1) | PT515310E (ko) |
RO (1) | RO111986B1 (ko) |
SA (1) | SA92130087B1 (ko) |
SK (1) | SK281615B6 (ko) |
UA (1) | UA39853C2 (ko) |
Families Citing this family (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6005001A (en) * | 1991-05-20 | 1999-12-21 | Novartis Ag (Formerly Sandoz Ag) | Pharmaceutical composition |
HU223343B1 (hu) * | 1991-05-20 | 2004-06-28 | Novartis Ag. | Allil-amin-származékot tartalmazó gyógyászati készítmények és eljárás azok előállítására |
HU219480B (hu) | 1991-05-23 | 2001-04-28 | Novartis Ag. | Eljárás gombás körömmegbetegségek ellen helyileg alkalmazható, allil-amin-származékot tartalmazó gyógyászati készítmények előállítására |
US20020048596A1 (en) * | 1994-12-30 | 2002-04-25 | Gregor Cevc | Preparation for the transport of an active substance across barriers |
WO2000024377A1 (en) * | 1998-10-23 | 2000-05-04 | Idea Innovative Dermale Applikationen Gmbh | Method for developing, testing and using associates of macromolecules and complex aggregates for improved payload and controllable de/association rates |
DK1031346T3 (da) | 1999-01-27 | 2002-08-12 | Idea Ag | Ikke-invasiv vaccination gennem huden |
PT1031347E (pt) | 1999-01-27 | 2002-09-30 | Idea Ag | Transporte/imunizacao transnasal com veiculos muitissimo adaptaveis |
WO2001001962A1 (en) * | 1999-07-05 | 2001-01-11 | Idea Ag. | A method for the improvement of transport across adaptable semi-permeable barriers |
GB0001928D0 (en) * | 2000-01-27 | 2000-03-22 | Novartis Ag | Organic compounds |
GB0003932D0 (en) * | 2000-02-18 | 2000-04-12 | Novartis Ag | Pharmaceutical compositions |
DE10011081A1 (de) * | 2000-03-09 | 2001-09-13 | Aventis Pharma Gmbh | Antiinfektive Wirkstoffkombinationen und ihre Verwendung zur topischen Behandlung von Pilzerkrankungen der Fuß- und Fingernägel |
US8257688B2 (en) * | 2000-03-27 | 2012-09-04 | Taro Pharmaceuticals Industries | Controlled delivery system of antifungal and keratolytic agents for local treatment of fungal infections of the nail and surrounding tissues |
US7074392B1 (en) * | 2000-03-27 | 2006-07-11 | Taro Pharmaceutical Industries Limited | Controllled delivery system of antifungal and keratolytic agents for local treatment of fungal infections |
DE10035991A1 (de) | 2000-07-24 | 2002-02-14 | Polichem Sa | Nagellackzusammensetzung |
KR100389671B1 (ko) * | 2000-11-24 | 2003-06-27 | 한미약품 주식회사 | 염산 테르비나핀을 함유하는 항진균제 외용 약제 조성물 |
US6490390B1 (en) * | 2001-01-05 | 2002-12-03 | Phaethon Communications | Grating writing systems based on an acousto-optic element |
KR100423666B1 (ko) * | 2001-02-07 | 2004-03-18 | 보령제약 주식회사 | 항진균 외용 제제 |
GB0103046D0 (en) | 2001-02-07 | 2001-03-21 | Novartis Ag | Organic Compounds |
GB0108082D0 (en) * | 2001-03-30 | 2001-05-23 | Novartis Consumer Health Sa | Topical composition |
BRPI0101486B1 (pt) * | 2001-04-17 | 2017-09-19 | Cristália Produtos Químicos Farmacêuticos Ltda. | Pharmaceutical composition for topic use containing heparin for the treatment of skin or mucosal injuries caused by burns |
US7244703B2 (en) | 2001-06-22 | 2007-07-17 | Bentley Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for peptide treatment |
US7473432B2 (en) * | 2002-10-11 | 2009-01-06 | Idea Ag | NSAID formulations, based on highly adaptable aggregates, for improved transport through barriers and topical drug delivery |
EP1663142A2 (en) * | 2003-06-23 | 2006-06-07 | MacroChem Corporation | Compositons and methods for topical administration |
JP5435836B2 (ja) * | 2003-07-03 | 2014-03-05 | 大正製薬株式会社 | 外用抗真菌剤組成物 |
KR100581169B1 (ko) * | 2003-07-07 | 2006-05-17 | 한국유나이티드제약 주식회사 | 용해도가 개선된 테르비나핀의 약제조성물 및 그 제조방법 |
JP2005104916A (ja) * | 2003-09-30 | 2005-04-21 | Kobayashi Pharmaceut Co Ltd | 抗真菌組成物 |
US7112561B2 (en) | 2003-12-08 | 2006-09-26 | Bentley Pharmaceuticals, Inc. | Pharmaceutical compositions and methods for insulin treatment |
US7618651B2 (en) * | 2004-06-24 | 2009-11-17 | Idexx Laboratories | Pharmaceutical compositions for drug delivery and methods of treating or preventing conditions using same |
US7854943B2 (en) * | 2004-06-24 | 2010-12-21 | Idexx Laboratories | Phospholipid gel compositions for drug delivery and methods of treating conditions using same |
US7858115B2 (en) * | 2004-06-24 | 2010-12-28 | Idexx Laboratories | Phospholipid gel compositions for drug delivery and methods of treating conditions using same |
WO2006003492A2 (en) * | 2004-07-02 | 2006-01-12 | Warner-Lambert Company Llc | Compositions and methods for treating pathological infections |
US7740875B2 (en) * | 2004-10-08 | 2010-06-22 | Mediquest Therapeutics, Inc. | Organo-gel formulations for therapeutic applications |
US20060078580A1 (en) | 2004-10-08 | 2006-04-13 | Mediquest Therapeutics, Inc. | Organo-gel formulations for therapeutic applications |
CA2584475A1 (en) * | 2004-11-12 | 2006-05-18 | Idea Ag | Extended surface aggregates in the treatment of skin conditions |
WO2006103638A2 (en) * | 2005-03-31 | 2006-10-05 | Ranbaxy Laboratories Limited | Topical pharmaceutical compositions of terbinafine and processes for their preparation |
JP2009502258A (ja) * | 2005-07-21 | 2009-01-29 | ノミール・メディカル・テクノロジーズ・インコーポレーテッド | 標的部位の生物学的汚染物質のレベルを下げる方法 |
US7359057B2 (en) * | 2005-08-26 | 2008-04-15 | Ball Aerospace & Technologies Corp. | Method and apparatus for measuring small shifts in optical wavelengths |
BRPI0616765A2 (pt) | 2005-09-29 | 2011-06-28 | Novartis Ag | composição antifúngica tópica adaptada para tratar uma infecção fúngica da pele, método para tratar uma infecção da pele por dermatófito, método para tratar infecção da pele e processo para a fabricação de uma composição farmacêutica tópica |
EP2121572A2 (en) * | 2006-12-08 | 2009-11-25 | Auspex Pharmaceuticals Inc. | Preparation and utility of substituted allylamines |
EP2120870A2 (en) * | 2007-02-21 | 2009-11-25 | Power Paper Ltd. | Terbinafine formulation for iontophoresis |
WO2008105038A1 (ja) * | 2007-02-23 | 2008-09-04 | Nichiban Company Limited | 抗真菌症用貼付剤 |
WO2008121709A1 (en) * | 2007-03-30 | 2008-10-09 | Transport Pharmaceuticals, Inc. | Pharmaceutical formulations for iontophoretic delivery of an anti-fungal drug |
US20090082469A1 (en) * | 2007-09-26 | 2009-03-26 | Protia, Llc | Deuterium-enriched terbinafine |
RU2011111206A (ru) * | 2008-10-31 | 2012-12-10 | Моберг Дерма Аб | Композиции для местного применения, содержащие комбинацию по меньшей мере двух агентов, усиливающих проникновение |
ES2598753T3 (es) | 2012-11-27 | 2017-01-30 | Eduardo Cos Alfonso | Composición farmacéutica para el tratamiento de la tendinitis calcificada y/o bursitis calcificada |
US9446131B2 (en) | 2013-01-31 | 2016-09-20 | Merz Pharmaceuticals, Llc | Topical compositions and methods for making and using same |
US9433680B2 (en) | 2013-01-31 | 2016-09-06 | Merz Pharmaceuticals, Llc | Topical compositions and methods for making and using same |
US9452173B2 (en) | 2013-01-31 | 2016-09-27 | Merz Pharmaceuticals, Llc | Topical compositions and methods for making and using same |
US8778365B1 (en) | 2013-01-31 | 2014-07-15 | Merz Pharmaceuticals, Llc | Topical compositions and methods for making and using same |
US8697753B1 (en) | 2013-02-07 | 2014-04-15 | Polichem Sa | Method of treating onychomycosis |
US20170266106A1 (en) | 2014-12-01 | 2017-09-21 | Achelios Therapeutics, Inc. | Methods and compositions for treating migraine and conditions associated with pain |
GB201511799D0 (en) * | 2015-07-06 | 2015-08-19 | Blueberry Therapeutics Ltd | Composition and methods of treatment |
US20180369174A1 (en) * | 2015-12-16 | 2018-12-27 | Achelios Therapeutics, Inc. | Methods and compositions for treating peripheral neuropathy |
TWI656883B (zh) * | 2017-08-21 | 2019-04-21 | 高雄醫學大學 | 光敏劑或其前驅藥物的醫藥載體 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1472793A (en) * | 1974-03-28 | 1977-05-04 | Ici Ltd | Pharmaceutical compositions |
DE2716943C2 (de) * | 1976-04-28 | 1986-08-14 | Sandoz-Patent-GmbH, 7850 Lörrach | N-(3-Phenyl-2-propenyl)-N-(1-naphthylmethyl)-amine, ihre Verwendung und Herstellung |
DE19375084I2 (de) * | 1979-08-22 | 2000-11-16 | Novartis Ag | Propenylamine Verfahren zu ihrer Herstellung sie enthaltende pharmazeutische Zusammensetzungen und ihre Verwendung als Arzneimittel |
FR2572933B1 (fr) * | 1981-04-06 | 1988-03-18 | Sandoz Sa | Compositions pharmaceutiques topiques a base de tizanidine |
FR2502951B1 (fr) * | 1981-04-06 | 1985-12-06 | Sandoz Sa | Compositions pharmaceutiques topiques sous forme d'une micro-emulsion |
JPS6058914A (ja) * | 1983-09-12 | 1985-04-05 | Shionogi & Co Ltd | イミダゾ−ル系抗真菌性外用ゲル製剤 |
US4912124A (en) * | 1984-02-23 | 1990-03-27 | Ortho Pharmaceutical Corporation | Antifungal dermatological solution |
JPS61151117A (ja) * | 1984-12-25 | 1986-07-09 | Bayer Yakuhin Kk | 抗真菌ゲル製剤 |
US4760096A (en) * | 1985-09-27 | 1988-07-26 | Schering Corporation | Moisturizing skin preparation |
JP2633555B2 (ja) * | 1987-03-23 | 1997-07-23 | 株式会社東芝 | 半導体装置の製造方法 |
ATE70446T1 (de) * | 1988-01-13 | 1992-01-15 | Sanol Arznei Schwarz Gmbh | Konzentrierte corticosteroide enthaltende loesungen und verfahren zu deren herstellung. |
US5160737A (en) * | 1988-05-03 | 1992-11-03 | Perio Products Ltd. | Liquid polymer composition, and method of use |
US5116603A (en) * | 1989-01-31 | 1992-05-26 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Oral antifungal preventative, and method of use |
HUT58201A (en) * | 1989-03-03 | 1992-02-28 | Sandoz Ag | Process for producing antiphlogistic pharmaceutical composition containing naphtalene-methan-amino derivatives |
FR2646603B1 (fr) * | 1989-05-03 | 1991-07-12 | Oreal | Composition nettoyante |
CA2020888A1 (en) * | 1989-07-27 | 1991-01-28 | Philippe Guerry | Substituted aminoalkoxybenzene derivatives |
FR2666962B1 (fr) * | 1990-09-26 | 1996-06-14 | Oreal | Composition antifongique sous forme de spray sec. |
FR2673537B1 (fr) * | 1991-03-08 | 1993-06-11 | Oreal | Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes. |
HU223343B1 (hu) * | 1991-05-20 | 2004-06-28 | Novartis Ag. | Allil-amin-származékot tartalmazó gyógyászati készítmények és eljárás azok előállítására |
-
1992
- 1992-05-06 HU HU9201518A patent/HU223343B1/hu active IP Right Grant
- 1992-05-11 DE DE4215450A patent/DE4215450B4/de not_active Expired - Lifetime
- 1992-05-12 IT ITRM920361A patent/IT1260710B/it active IP Right Grant
- 1992-05-13 FR FR9205902A patent/FR2676646B1/fr not_active Expired - Lifetime
- 1992-05-13 LU LU88114A patent/LU88114A1/fr unknown
- 1992-05-15 CH CH1564/92A patent/CH683823A5/de not_active IP Right Cessation
- 1992-05-18 CZ CZ971292A patent/CZ285275B6/cs not_active IP Right Cessation
- 1992-05-18 AU AU16317/92A patent/AU647922B2/en not_active Expired
- 1992-05-18 ES ES92810372T patent/ES2186668T3/es not_active Expired - Lifetime
- 1992-05-18 EP EP92810372A patent/EP0515310B1/en not_active Expired - Lifetime
- 1992-05-18 DK DK92810372T patent/DK0515310T3/da active
- 1992-05-18 SK SK1491-92A patent/SK281615B6/sk not_active IP Right Cessation
- 1992-05-18 CZ CS921491A patent/CZ283019B6/cs not_active IP Right Cessation
- 1992-05-18 FI FI922252A patent/FI102458B/fi not_active IP Right Cessation
- 1992-05-18 PT PT92810372T patent/PT515310E/pt unknown
- 1992-05-18 RO RO92-200691A patent/RO111986B1/ro unknown
- 1992-05-18 IL IL10190392A patent/IL101903A/en not_active IP Right Cessation
- 1992-05-18 NO NO921958A patent/NO180772C/no not_active IP Right Cessation
- 1992-05-18 GB GB9210579A patent/GB2255908B/en not_active Expired - Lifetime
- 1992-05-18 MX MX9202328A patent/MX9202328A/es unknown
- 1992-05-19 KR KR1019920008401A patent/KR100303095B1/ko not_active IP Right Cessation
- 1992-05-19 AT AT0102392A patent/AT400517B/de not_active IP Right Cessation
- 1992-05-19 CA CA002068957A patent/CA2068957C/en not_active Expired - Lifetime
- 1992-05-19 JP JP4125921A patent/JP2651311B2/ja not_active Expired - Lifetime
- 1992-07-01 IE IE921599A patent/IE70913B1/en not_active IP Right Cessation
- 1992-09-07 SA SA92130087A patent/SA92130087B1/ar unknown
-
1993
- 1993-06-18 UA UA93003146A patent/UA39853C2/uk unknown
-
1994
- 1994-04-18 US US08/228,841 patent/US5681849A/en not_active Expired - Lifetime
-
1996
- 1996-08-08 HK HK148896A patent/HK148896A/xx not_active IP Right Cessation
-
1997
- 1997-05-16 CY CY194297A patent/CY1942A/xx unknown
- 1997-07-22 US US08/898,348 patent/US5856355A/en not_active Expired - Lifetime
-
1998
- 1998-08-18 FI FI981777A patent/FI981777A/fi unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
EXP | Patent expired |