HUP0302943A2 - Új heterociklusos vegyületek, előállításuk és alkalmazásuk gyógyszerekként, különösen antibakteriális szerekként - Google Patents

Új heterociklusos vegyületek, előállításuk és alkalmazásuk gyógyszerekként, különösen antibakteriális szerekként

Info

Publication number
HUP0302943A2
HUP0302943A2 HU0302943A HUP0302943A HUP0302943A2 HU P0302943 A2 HUP0302943 A2 HU P0302943A2 HU 0302943 A HU0302943 A HU 0302943A HU P0302943 A HUP0302943 A HU P0302943A HU P0302943 A2 HUP0302943 A2 HU P0302943A2
Authority
HU
Hungary
Prior art keywords
group
general formula
hydrogen atom
antibacterial agents
compounds
Prior art date
Application number
HU0302943A
Other languages
English (en)
Inventor
József Aszodi
Claude Fromentin
Maxime Lampilas
David Alan Rowlands
Original Assignee
Aventis Pharma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8853181&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0302943(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma S.A. filed Critical Aventis Pharma S.A.
Publication of HUP0302943A2 publication Critical patent/HUP0302943A2/hu
Publication of HUP0302943A3 publication Critical patent/HUP0302943A3/hu
Publication of HU226889B1 publication Critical patent/HU226889B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

A találmány tárgyát új, (I) általános képletű heterociklusosvegyületek és bázissal vagy savval alkotott sóik képezik. A találmánytárgya továbbá eljárás ezeknek a vegyületeknek az előállítására,valamint a vegyületek alkalmazása. A találmány szerinti vegyületekelsősorban antibakteriális szerekként alkalmazhatók. Az (I) általánosképletben R1 jelentése hidrogénatom, COOH-, CN-, COOR-, CONR6R7-,(CH2)n'R5- vagy (1) általános képletű csoport, R2 jelentésehidrogénatom vagy (CH2)n'1R5-csoport, ahol n'1 jelentése 0, 1 vagy 2,és R5 jelentése a fenti; R3 jelentése hidrogénatom vagy 1-6 szénatomosalkilcsoport; A jelentése kémiai kötés két olyan szénatom között,amelyhez R1 és R2 kapcsolódik, vagy (2) általános képletű csoport,ahol R4 jelentése hidrogénatom vagy (CH2)n'1R5-csoport, ahol n'1 és R5jelentése a fenti, a (2) általános képletben a szaggatott vonaljelentése adott esetben létesített kötés azon szénatomok egyikével,amelyekhez R1 és R2 kapcsolódik; n jelentése 1 vagy 2; X jelentése kétvegyértékű -C(O)-B-csoport, amely a szénatomnál kapcsolódik anitrogénatomhoz. Ó
HU0302943A 2000-08-01 2001-07-24 New heterocyclic compounds, preparation thereof and use as medicines, in particular as antibacterial agents HU226889B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0010121A FR2812635B1 (fr) 2000-08-01 2000-08-01 Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens
PCT/FR2001/002418 WO2002010172A1 (fr) 2000-08-01 2001-07-24 Composes azabicycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens

Publications (3)

Publication Number Publication Date
HUP0302943A2 true HUP0302943A2 (hu) 2003-12-29
HUP0302943A3 HUP0302943A3 (en) 2007-08-28
HU226889B1 HU226889B1 (en) 2010-01-28

Family

ID=8853181

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0302943A HU226889B1 (en) 2000-08-01 2001-07-24 New heterocyclic compounds, preparation thereof and use as medicines, in particular as antibacterial agents

Country Status (42)

Country Link
US (5) US7112592B2 (hu)
EP (1) EP1307457B1 (hu)
JP (2) JP4515704B2 (hu)
KR (1) KR100632906B1 (hu)
CN (1) CN1289500C (hu)
AP (1) AP1614A (hu)
AR (1) AR031716A1 (hu)
AT (1) ATE263768T1 (hu)
AU (2) AU7990501A (hu)
BG (1) BG66094B1 (hu)
BR (1) BRPI0112986B8 (hu)
CA (1) CA2417475C (hu)
CR (1) CR6895A (hu)
CZ (1) CZ294956B6 (hu)
DE (1) DE60102702T2 (hu)
DK (1) DK1307457T3 (hu)
DZ (1) DZ3397A1 (hu)
EA (1) EA004920B1 (hu)
EC (1) ECSP034460A (hu)
EE (1) EE05183B1 (hu)
ES (1) ES2220793T3 (hu)
FR (1) FR2812635B1 (hu)
HK (1) HK1060356A1 (hu)
HR (1) HRP20030034B1 (hu)
HU (1) HU226889B1 (hu)
IL (2) IL154187A0 (hu)
MA (1) MA26938A1 (hu)
ME (2) ME00060B (hu)
MX (1) MXPA03000881A (hu)
NO (1) NO324940B1 (hu)
NZ (1) NZ523707A (hu)
OA (1) OA12347A (hu)
PL (2) PL234468B1 (hu)
PT (1) PT1307457E (hu)
RS (1) RS50214B (hu)
SI (1) SI1307457T1 (hu)
SK (1) SK287597B6 (hu)
TR (1) TR200400859T4 (hu)
TW (1) TWI292401B (hu)
UA (1) UA73791C2 (hu)
WO (1) WO2002010172A1 (hu)
ZA (1) ZA200300676B (hu)

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