HUE037600T2 - Vegyületek és készítmények paraziták által okozott fertõzések kezelésére - Google Patents
Vegyületek és készítmények paraziták által okozott fertõzések kezeléséreInfo
- Publication number
- HUE037600T2 HUE037600T2 HUE13795977A HUE13795977A HUE037600T2 HU E037600 T2 HUE037600 T2 HU E037600T2 HU E13795977 A HUE13795977 A HU E13795977A HU E13795977 A HUE13795977 A HU E13795977A HU E037600 T2 HUE037600 T2 HU E037600T2
- Authority
- HU
- Hungary
- Prior art keywords
- compositions
- compounds
- treatment
- parasitic diseases
- parasitic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261728018P | 2012-11-19 | 2012-11-19 | |
US201361847860P | 2013-07-18 | 2013-07-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
HUE037600T2 true HUE037600T2 (hu) | 2018-09-28 |
Family
ID=49667630
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE13795977A HUE037600T2 (hu) | 2012-11-19 | 2013-11-18 | Vegyületek és készítmények paraziták által okozott fertõzések kezelésére |
Country Status (19)
Country | Link |
---|---|
US (3) | US9556169B2 (hu) |
EP (1) | EP2925757B1 (hu) |
JP (1) | JP6298472B2 (hu) |
CN (1) | CN105164124B (hu) |
AR (1) | AR093532A1 (hu) |
CY (1) | CY1119727T1 (hu) |
DK (1) | DK2925757T3 (hu) |
ES (1) | ES2655030T3 (hu) |
HR (1) | HRP20171998T1 (hu) |
HU (1) | HUE037600T2 (hu) |
LT (1) | LT2925757T (hu) |
ME (1) | ME03042B (hu) |
PL (1) | PL2925757T3 (hu) |
PT (1) | PT2925757T (hu) |
RS (1) | RS56720B1 (hu) |
SI (1) | SI2925757T1 (hu) |
TW (1) | TWI600654B (hu) |
UY (1) | UY35146A (hu) |
WO (1) | WO2014078802A1 (hu) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MA41338B1 (fr) * | 2015-01-16 | 2019-07-31 | Hoffmann La Roche | Composés de pyrazine pour le traitement de maladies infectieuses |
CN108495853A (zh) | 2016-01-21 | 2018-09-04 | 诺华股份有限公司 | 用于治疗隐孢子虫病的化合物和组合物 |
TWI679197B (zh) * | 2016-05-05 | 2019-12-11 | 瑞士商伊蘭科動物健康公司 | 雜芳基-1,2,4-***及雜芳基-***化合物 |
EP3484886B1 (en) * | 2016-07-14 | 2020-03-04 | Hoffmann-La Roche AG | 6,7-dihydro-4h-pyrazolo[1,5-a]pyrazine and 6,7-dihydro-4h-triazolo[1,5-a]pyrazine compounds for the treatment of infectious diseases |
EP3526220A1 (en) * | 2016-10-13 | 2019-08-21 | The U.S.A. as represented by the Secretary, Department of Health and Human Services | Compounds and method for blocking transmission of malarial parasite |
WO2018160845A1 (en) * | 2017-03-01 | 2018-09-07 | Anacor Pharmaceuticals, Inc. | Novel oxaborole analogs and uses thereof |
BR112019019494A2 (pt) * | 2017-03-20 | 2020-04-28 | Harvard College | compostos e métodos para o tratamento de doenças parasitárias |
CN107037148B (zh) * | 2017-04-07 | 2019-11-19 | 上海药明康德新药开发有限公司 | 卤泛曲林的高效液相检测方法 |
JOP20190278A1 (ar) | 2017-05-31 | 2019-11-28 | Novartis Ag | مركبات 5، 6-ثنائية الحلقة مندمجة وتركيبات لعلاج الأمراض الطفيلية |
AU2019301510A1 (en) * | 2018-07-09 | 2021-03-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Anthelminthic heterocyclic compounds |
GB201811695D0 (en) * | 2018-07-17 | 2018-08-29 | Salvensis | Compounds for use in the treatment of fascioliasis |
EP3941587A1 (en) | 2019-03-19 | 2022-01-26 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic aza-benzothiophene and aza-benzofuran compounds |
AU2020289459A1 (en) * | 2019-06-07 | 2022-01-06 | Elanco Tiergesundheit Ag | Bicyclic derivatives for treating endoparasites |
CA3183100A1 (en) | 2020-05-29 | 2021-12-02 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Anthelmintic heterocyclic compounds |
WO2023275590A1 (en) | 2021-06-29 | 2023-01-05 | Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. | Detection of phosphoinositides in blood cells as a biomarker for alpha synuclein associated pathologies and a method of treatment of parkinson's disease and the related neurodegenerations |
WO2023057394A1 (en) | 2021-10-04 | 2023-04-13 | Forx Therapeutics Ag | N,n-dimethyl-4-(7-(n-(1-methylcyclopropyl)sulfamoyl)-imidazo[1,5-a]pyridin-5-yl)piperazine-1-carboxamide derivatives and the corresponding pyrazolo[1,5-a]pyridine derivatives as parg inhibitors for the treatment of cancer |
CA3181279A1 (en) * | 2022-03-24 | 2023-09-24 | Bloom Energy Corporation | Fuel cell stack assembly including heat sink inserts |
US20240124450A1 (en) | 2022-09-21 | 2024-04-18 | Pfizer Inc. | Novel SIK Inhibitors |
Family Cites Families (82)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH11505524A (ja) | 1995-05-01 | 1999-05-21 | 藤沢薬品工業株式会社 | イミダゾ1,2−aピリジンおよびイミダゾ1,2−aピリデジン誘導体、および骨吸収阻害剤としてのその用途 |
EP0915880B1 (en) | 1996-07-24 | 2007-10-10 | Bristol-Myers Squibb Pharma Company | Azolo triazines and pyrimidines |
CA2295239A1 (en) | 1997-06-27 | 1999-01-07 | Fujisawa Pharmaceutical Co., Ltd. | Sulfonamide compounds and medicinal use thereof |
JP2001139575A (ja) | 1999-11-15 | 2001-05-22 | Fujisawa Pharmaceut Co Ltd | 新規ピラゾロピリジン誘導体 |
GB0002312D0 (en) | 2000-02-01 | 2000-03-22 | Glaxo Group Ltd | Medicaments |
GB0002336D0 (en) | 2000-02-01 | 2000-03-22 | Glaxo Group Ltd | Medicaments |
ATE414079T1 (de) * | 2000-03-01 | 2008-11-15 | Janssen Pharmaceutica Nv | 2,4-disubstituierte thiazolyl derivate |
JP2003531906A (ja) | 2000-04-28 | 2003-10-28 | グラクソ グループ リミテッド | ピラゾロピリジン誘導体の製造方法 |
GB0018473D0 (en) | 2000-07-27 | 2000-09-13 | Merck Sharp & Dohme | Therapeutic agents |
PE20020506A1 (es) * | 2000-08-22 | 2002-07-09 | Glaxo Group Ltd | Derivados de pirazol fusionados como inhibidores de la proteina cinasa |
AUPQ969800A0 (en) | 2000-08-28 | 2000-09-21 | Fujisawa Pharmaceutical Co., Ltd. | Pyrazolopyridine compound and pharmaceutical use thereof |
EP1217000A1 (en) | 2000-12-23 | 2002-06-26 | Aventis Pharma Deutschland GmbH | Inhibitors of factor Xa and factor VIIa |
EP1382603B1 (en) | 2001-04-26 | 2008-07-23 | Eisai R&D Management Co., Ltd. | Nitrogenous fused-ring compound having pyrazolyl group as substituent and medicinal composition thereof |
AUPR916301A0 (en) | 2001-11-29 | 2001-12-20 | Fujisawa Pharmaceutical Co., Ltd. | Pyrazolopyridine compound and pharmaceutical use thereof |
US7662826B2 (en) | 2002-04-23 | 2010-02-16 | Shionogi & Co., Ltd. | Pyrazolo [1,5-a] pyrimidine derivative and nad (p) h oxidase inhibitor containing the same |
US8673924B2 (en) | 2002-09-04 | 2014-03-18 | Merck Sharp & Dohme Corp. | Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors |
US7119200B2 (en) | 2002-09-04 | 2006-10-10 | Schering Corporation | Pyrazolopyrimidines as cyclin dependent kinase inhibitors |
ATE370139T1 (de) | 2002-09-17 | 2007-09-15 | Lilly Co Eli | Pyrazolopyridin derivate als tgf beta hemmstoffe zur behandlung von krebs |
US7329658B2 (en) | 2003-02-06 | 2008-02-12 | Pfizer Inc | Cannabinoid receptor ligands and uses thereof |
US7176210B2 (en) | 2003-02-10 | 2007-02-13 | Pfizer Inc. | Cannabinoid receptor ligands and uses thereof |
CA2514733A1 (en) | 2003-02-28 | 2004-09-16 | Transform Pharmaceuticals, Inc. | Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen |
US7504424B2 (en) | 2004-07-16 | 2009-03-17 | Schering Corporation | Compounds for the treatment of inflammatory disorders |
US7488745B2 (en) * | 2004-07-16 | 2009-02-10 | Schering Corporation | Compounds for the treatment of inflammatory disorders |
RU2007105685A (ru) * | 2004-07-16 | 2008-08-27 | Шеринг Корпорейшн (US) | Производные гидантонина для лечения воспалительных заболеваний |
BRPI0514094A (pt) | 2004-08-02 | 2008-05-27 | Osi Pharm Inc | composto, composição, e, método de tratamento de distúrbio hiperproliferativo |
JP2008516962A (ja) | 2004-10-15 | 2008-05-22 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 血管傷害を治療する方法 |
EP1813613B1 (en) | 2004-11-08 | 2012-12-19 | Msd K.K. | Novel fused imidazole derivative |
DE602005014382D1 (de) * | 2004-12-21 | 2009-06-18 | Smithkline Beecham Corp | 2-pyrimidinyl-pyrazolopyridin-erbb-kinaseinhibitoren |
JPWO2006070943A1 (ja) | 2004-12-28 | 2008-06-12 | 武田薬品工業株式会社 | 縮合イミダゾール化合物およびその用途 |
US7713975B1 (en) | 2005-01-12 | 2010-05-11 | Alcon, Inc. | 3,6-substituted imidazol[1,2-b]pyridazine analogs for treating allergic and inflammatory diseases |
US20100216798A1 (en) | 2005-07-29 | 2010-08-26 | Astellas Pharma Inc | Fused heterocycles as lck inhibitors |
WO2007025090A2 (en) | 2005-08-25 | 2007-03-01 | Kalypsys, Inc. | Heterobicyclic and - tricyclic inhibitors of mapk/erk kinase |
DE102005042742A1 (de) | 2005-09-02 | 2007-03-08 | Schering Ag | Substituierte Imidazo[1,2b]pyridazine als Kinase-Inhibitoren, deren Herstellung und Verwendung als Arzneimittel |
EP1928237A4 (en) | 2005-09-02 | 2011-03-09 | Abbott Lab | NEW HETEROCYCLES BASED ON IMIDAZO |
KR101289995B1 (ko) | 2005-09-27 | 2013-07-26 | 시오노기 앤드 컴파니, 리미티드 | Pgd2 수용체 길항제 활성을 갖는 설폰아마이드 유도체 |
US20070129364A1 (en) | 2005-12-07 | 2007-06-07 | Han-Qing Dong | Pyrrolopyridine kinase inhibiting compounds |
EP1963316A2 (en) | 2005-12-08 | 2008-09-03 | Novartis AG | Pyrazolo[1,5-a]pyridine-3-carboxylic acids as ephb and vegfr2 kinase inhibitors |
WO2007086080A2 (en) | 2006-01-30 | 2007-08-02 | Glenmark Pharmaceuticals Limited | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
WO2007100775A2 (en) | 2006-02-27 | 2007-09-07 | Alexander Michalow | Methods for regulating neurotransmitter systems by inducing counteradaptations |
WO2007096764A2 (en) | 2006-02-27 | 2007-08-30 | Glenmark Pharmaceuticals S.A. | Bicyclic heteroaryl derivatives as cannabinoid receptor modulators |
EP2038279A2 (en) | 2006-06-06 | 2009-03-25 | Avigen, Inc. | Substituted pyrazolo [1,5- alpha] pyridine compounds and their methods of use |
DE102006029447A1 (de) | 2006-06-21 | 2007-12-27 | Bayer Schering Pharma Ag | Oxo-substituierte Imidazo[1,2b]pyridazine, deren Herstellung und Verwendung als Arzneimittel |
EP1873157A1 (en) | 2006-06-21 | 2008-01-02 | Bayer Schering Pharma Aktiengesellschaft | Pyrazolopyrimidines and salts thereof, pharmaceutical compositions comprising same, methods of preparing same and uses of same |
EP1900739A1 (en) | 2006-08-30 | 2008-03-19 | Cellzome Ag | Diazolodiazine derivatives as kinase inhibitors |
EP2063962A2 (en) | 2006-09-07 | 2009-06-03 | Biogen Idec MA Inc. | Irak modulators for treating an inflammatory condition, cell proliferative disorder, immune disorder |
EP2062048A4 (en) | 2006-09-12 | 2009-12-02 | Gen Hospital Corp | METHODS OF IDENTIFYING COMPOUNDS THAT MODULATE CELL SIGNALING AND METHODS EMPLOYING SUCH COMPOUNDS |
US20090286779A1 (en) | 2006-09-29 | 2009-11-19 | Novartis Ag | Pyrazolopyrimidines as lipid kinase inhibitors |
RU2009120389A (ru) | 2006-10-30 | 2010-12-10 | Новартис АГ (CH) | Гетероциклические соединения в качестве противовоспалительных агентов |
CN101600718B (zh) | 2006-11-06 | 2013-07-03 | 特雷罗药物股份有限公司 | 咪唑并[1,2-b]哒嗪和吡唑并[1,5-a]嘧啶衍生物及其作为蛋白激酶抑制剂的用途 |
WO2008072682A1 (ja) | 2006-12-15 | 2008-06-19 | Daiichi Sankyo Company, Limited | イミダゾ[1,2-b]ピリダジン誘導体 |
AR064420A1 (es) | 2006-12-21 | 2009-04-01 | Alcon Mfg Ltd | Composiciones farmaceuticas oftalmicas que comprenden una cantidad efectiva de analogos de 6-aminoimidazo[1,2b]piridazinas, utiles para el tratamiento del glaucoma y/o controlar la presion intraocular normal o elevada(iop). |
JP5442448B2 (ja) | 2006-12-22 | 2014-03-12 | アステックス、セラピューティックス、リミテッド | Fgfrインヒビターとしての二環式ヘテロ環式化合物 |
WO2008094737A2 (en) | 2007-01-26 | 2008-08-07 | Irm Llc | Purine compounds and compositions as kinase inhibitors for the treatment of plasmodium related diseases |
AU2008266856A1 (en) | 2007-06-18 | 2008-12-24 | University Of Louisville Research Foundation, Inc. | Family of PFKFB3 inhibitors with anti-neoplastic activities |
CA2692653A1 (en) | 2007-07-11 | 2009-01-15 | Auckland Uniservices Limited | Pyrazolo[1,5-.alpha.]pyridines and their use in cancer therapy |
MY154668A (en) | 2007-07-19 | 2015-07-15 | Lundbeck & Co As H | 5-membered heterocyclic amides and related compounds |
WO2009017954A1 (en) | 2007-08-01 | 2009-02-05 | Phenomix Corporation | Inhibitors of jak2 kinase |
AU2009218459A1 (en) | 2008-02-28 | 2009-09-03 | Novartis Ag | Imidazo [1,2-B] pyridazine derivatives for the treatment of C-Met tyrosine kinase mediated disease |
US8507501B2 (en) | 2008-03-13 | 2013-08-13 | The Brigham And Women's Hospital, Inc. | Inhibitors of the BMP signaling pathway |
EP2300469B1 (en) | 2008-05-13 | 2015-06-24 | Novartis AG | Fused nitrogen containing heterocycles and compositions thereof as kinase inhibitors |
JP2009298710A (ja) | 2008-06-11 | 2009-12-24 | Daiichi Sankyo Co Ltd | イミダゾ[1,2−b]ピリダジン誘導体含有医薬組成物 |
EP2942392B1 (en) | 2008-06-30 | 2018-10-03 | Janssen Biotech, Inc. | Differentiation of pluripotent stem cells |
WO2010017046A1 (en) | 2008-08-05 | 2010-02-11 | Merck & Co., Inc. | Pyrazolo[1,5-a]pyridines as mark inhibitors |
WO2010017047A1 (en) | 2008-08-05 | 2010-02-11 | Merck & Co., Inc. | Therapeutic compounds |
US8198449B2 (en) | 2008-09-11 | 2012-06-12 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
US8293909B2 (en) | 2008-09-11 | 2012-10-23 | Bristol-Myers Squibb Company | Compounds for the treatment of hepatitis C |
ES2710701T3 (es) * | 2008-09-24 | 2019-04-26 | Basf Se | Compuestos de pirazol para el control de plagas de invertebrados |
WO2010059836A1 (en) | 2008-11-20 | 2010-05-27 | Decode Genetics Ehf | Substituted aza-bridged bicyclics for cardiovascular and cns disease |
DK2376490T3 (da) | 2008-12-04 | 2013-04-15 | Proximagen Ltd | Imidazopyridinforbindelser |
WO2010074586A1 (en) | 2008-12-23 | 2010-07-01 | Pathway Therapeutics Limited | Pyrazolo[1,5-a]pyridine and imidazo[1,2-a]pyridine derivatives and their use in cancer therapy |
CN102395585A (zh) | 2009-01-30 | 2012-03-28 | 米伦纽姆医药公司 | 杂芳基化合物和其作为pi3k抑制剂的用途 |
WO2010108074A2 (en) | 2009-03-20 | 2010-09-23 | Amgen Inc. | Inhibitors of pi3 kinase |
WO2010108187A2 (en) | 2009-03-20 | 2010-09-23 | Brandeis University | Compounds and methods for treating mammalian gastrointestinal microbial infections |
US8927545B2 (en) | 2009-03-30 | 2015-01-06 | Duke University | Inhibiting Eph B-3 kinase |
WO2010118207A1 (en) | 2009-04-09 | 2010-10-14 | Schering Corporation | Pyrazolo [1, 5-a] pyrimidine derivatives as mtor inhibitors |
TWI421252B (zh) * | 2009-07-09 | 2014-01-01 | Irm Llc | 用於治療寄生蟲疾病之化合物及組合物 |
RU2421455C2 (ru) | 2009-07-14 | 2011-06-20 | Государственное образовательное учреждение высшего профессионального образования "Пермский государственный университет" | СПОСОБ ПОЛУЧЕНИЯ МЕТИЛ 7-АРИЛКАРБАМОИЛ-6-БЕНЗОИЛ-2-МЕТИЛ-3-ФЕНИЛПИРАЗОЛО[1,5-a]ПИРИМИДИН-5-КАРБОКСИЛАТОВ |
TW201107329A (en) | 2009-07-30 | 2011-03-01 | Oncotherapy Science Inc | Fused imidazole derivative having ttk inhibitory action |
TW201113286A (en) | 2009-09-03 | 2011-04-16 | Array Biopharma Inc | Substituted pyrazolo[1,5-a]pyrimidine compounds as mTOR inhibitors |
EP2480548A4 (en) | 2009-09-23 | 2013-02-20 | Panmira Pharmaceuticals Llc | INDOLIZIN 5-LIPOXYGENASE INHIBITORS |
GB201002911D0 (en) | 2010-02-19 | 2010-04-07 | Medical Res Council | Compound |
EP2920177A1 (en) | 2012-11-19 | 2015-09-23 | Novartis AG | Compounds and compositions for the treatment of parasitic diseases |
-
2013
- 2013-11-18 JP JP2015542882A patent/JP6298472B2/ja not_active Expired - Fee Related
- 2013-11-18 TW TW102141950A patent/TWI600654B/zh not_active IP Right Cessation
- 2013-11-18 WO PCT/US2013/070601 patent/WO2014078802A1/en active Application Filing
- 2013-11-18 EP EP13795977.1A patent/EP2925757B1/en active Active
- 2013-11-18 DK DK13795977.1T patent/DK2925757T3/en active
- 2013-11-18 CN CN201380070822.0A patent/CN105164124B/zh not_active Expired - Fee Related
- 2013-11-18 RS RS20171296A patent/RS56720B1/sr unknown
- 2013-11-18 PL PL13795977T patent/PL2925757T3/pl unknown
- 2013-11-18 ME MEP-2017-266A patent/ME03042B/me unknown
- 2013-11-18 US US14/443,609 patent/US9556169B2/en active Active
- 2013-11-18 HU HUE13795977A patent/HUE037600T2/hu unknown
- 2013-11-18 ES ES13795977.1T patent/ES2655030T3/es active Active
- 2013-11-18 PT PT137959771T patent/PT2925757T/pt unknown
- 2013-11-18 LT LTEP13795977.1T patent/LT2925757T/lt unknown
- 2013-11-18 SI SI201330889T patent/SI2925757T1/en unknown
- 2013-11-19 UY UY0001035146A patent/UY35146A/es unknown
- 2013-11-19 AR ARP130104250A patent/AR093532A1/es unknown
-
2016
- 2016-07-26 US US15/220,149 patent/US9926314B2/en not_active Expired - Fee Related
-
2017
- 2017-12-27 HR HRP20171998TT patent/HRP20171998T1/hr unknown
-
2018
- 2018-01-03 CY CY20181100008T patent/CY1119727T1/el unknown
- 2018-02-06 US US15/889,578 patent/US20180230145A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20150344471A1 (en) | 2015-12-03 |
TW201429967A (zh) | 2014-08-01 |
PT2925757T (pt) | 2018-01-09 |
TWI600654B (zh) | 2017-10-01 |
US9926314B2 (en) | 2018-03-27 |
US20160333012A1 (en) | 2016-11-17 |
DK2925757T3 (en) | 2018-01-15 |
LT2925757T (lt) | 2017-12-27 |
ES2655030T3 (es) | 2018-02-16 |
HRP20171998T1 (hr) | 2018-02-09 |
CN105164124B (zh) | 2017-03-15 |
CY1119727T1 (el) | 2018-06-27 |
JP2016505529A (ja) | 2016-02-25 |
EP2925757A1 (en) | 2015-10-07 |
SI2925757T1 (en) | 2018-01-31 |
RS56720B1 (sr) | 2018-03-30 |
UY35146A (es) | 2014-06-30 |
US9556169B2 (en) | 2017-01-31 |
CN105164124A (zh) | 2015-12-16 |
WO2014078802A1 (en) | 2014-05-22 |
PL2925757T3 (pl) | 2018-06-29 |
US20180230145A1 (en) | 2018-08-16 |
EP2925757B1 (en) | 2017-10-04 |
JP6298472B2 (ja) | 2018-03-20 |
ME03042B (me) | 2018-10-20 |
AR093532A1 (es) | 2015-06-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HUE037600T2 (hu) | Vegyületek és készítmények paraziták által okozott fertõzések kezelésére | |
IL241264A0 (en) | Compounds and compositions for the treatment of parasitic diseases | |
HK1212632A1 (zh) | 用於治療 介導的疾病的藥物組合物 | |
HUE041553T2 (hu) | Lizoszomális tárolási betegségek (LSD) kezelése és génterápia | |
IL236221A (en) | History of theophyridone and pharmacological preparations containing them for the treatment of diseases | |
HK1213798A1 (zh) | 治療性化合物和組合物 | |
EP2872151A4 (en) | ACELLULAR PRO-TOLEROGENIC COMPOSITIONS FOR THE TREATMENT OR PREVENTION OF AUTOIMMUNE DISEASES | |
EP2827856A4 (en) | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF MUSCLE DISEASES | |
EP2621499A4 (en) | METHODS OF TREATING ALLERGIC DISEASES | |
EP2773342A4 (en) | COMPOSITIONS USEFUL FOR THE TREATMENT OF VIRAL DISEASES | |
HK1198909A1 (en) | Compositions and methods for the treatment of hepatic diseases and disorders | |
HK1205502A1 (en) | Compounds for the treatment of mtor pathway related diseases mtor | |
HK1215794A1 (zh) | 用於治療疾病的同種異體自噬體富集組合物 | |
ZA201408055B (en) | Compositions and methods for the treatment of local pain | |
IL238592B (en) | Compounds for the treatment of liver diseases | |
SG11201404649UA (en) | Novel compounds for the treatment of dyslipidemia and related diseases | |
EP2709632A4 (en) | COMPOSITIONS AND METHOD FOR THE TREATMENT OF SKIN DISEASES | |
ITRM20120530A1 (it) | Compounds for use in the treatment of parasitic diseases | |
HUP1100290A2 (en) | Combination compositions for the treatment of proliferative diseases | |
IL234796B (en) | Compounds for the treatment of diseases related to ischemia-reperfusion | |
SI2812351T1 (sl) | Farmacevtski sestavek za zdravljenje multiple skleroze | |
HK1157189A1 (en) | Pharmaceutical composition for the treatment of tumor diseases | |
HUP1100245A2 (en) | Pharmaceutical composition for the treatment of wounds |