HU179967B - Process for preparing 7-acyl-amido-3-thiomethyl-3-cefem-carboxylic acid derivatives - Google Patents

Process for preparing 7-acyl-amido-3-thiomethyl-3-cefem-carboxylic acid derivatives Download PDF

Info

Publication number: HU179967B
Authority: HU; Hungary
Prior art keywords: methyl; formula; compound; reaction; acetamido
Prior art date: 1977-03-07

Application number

HU78EI784A

Other languages

German (de)

English (en)

Hungarian (hu)

Inventor

Lowell D Hatfield

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-03-07

Filing date

1978-03-03

Publication date

1983-01-28

1977-12-27 Priority claimed from US05/862,871 external-priority patent/US4144391A/en

1978-03-03 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1983-01-28 Publication of HU179967B publication Critical patent/HU179967B/hu

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

HU78EI784A 1977-03-07 1978-03-03 Process for preparing 7-acyl-amido-3-thiomethyl-3-cefem-carboxylic acid derivatives HU179967B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US77501877A	1977-03-07	1977-03-07
US05/862,871 US4144391A (en)	1977-03-07	1977-12-27	Cephalosporin displacement reaction

Publications (1)

Publication Number	Publication Date
HU179967B true HU179967B (en)	1983-01-28

Family

ID=27118982

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HU78EI784A HU179967B (en)	1977-03-07	1978-03-03	Process for preparing 7-acyl-amido-3-thiomethyl-3-cefem-carboxylic acid derivatives

Country Status (30)

Country	Link
JP (1)	JPS53130689A (es)
AT (1)	AT366696B (es)
AU (1)	AU515428B2 (es)
BG (1)	BG31379A3 (es)
CA (1)	CA1083141A (es)
CH (1)	CH637964A5 (es)
CS (1)	CS205115B2 (es)
CY (1)	CY1196A (es)
DD (1)	DD137356A5 (es)
DE (1)	DE2809058A1 (es)
DK (1)	DK97378A (es)
EG (1)	EG13454A (es)
ES (1)	ES467637A1 (es)
FI (1)	FI69309C (es)
FR (1)	FR2383189A1 (es)
GB (1)	GB1597036A (es)
GR (1)	GR68893B (es)
HK (1)	HK49083A (es)
HU (1)	HU179967B (es)
IE (1)	IE46437B1 (es)
IL (1)	IL54181A (es)
IT (1)	IT1093504B (es)
MX (1)	MX5142E (es)
NL (1)	NL190703C (es)
NZ (1)	NZ186610A (es)
PH (1)	PH14596A (es)
PL (1)	PL122152B1 (es)
PT (1)	PT67732A (es)
SE (1)	SE437991B (es)
YU (1)	YU51478A (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5543043A (en) *	1978-09-22	1980-03-26	Sankyo Co Ltd	Preparation of 3-substituted thiomethylcephalosporin derivative
US4576937A (en) *	1984-02-29	1986-03-18	Smithkline Beckman Corporation	7-D-Mandelamido-3(1-sulfomethyltetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid monosodium salt
GB8519606D0 (en) *	1985-08-05	1985-09-11	Fujisawa Pharmaceutical Co	3 7-d substituted-3-cephem compounds
JP2503500B2 (ja) *	1986-04-14	1996-06-05	萬有製薬株式会社	新規セフアロスポリン誘導体及びその製造法
JPS62281881A (ja) *	1986-09-08	1987-12-07	Sankyo Co Ltd	３−置換チオメチルセフアロスポリン誘導体の製法
EP2539348A4 (en) *	2010-02-26	2013-07-24	Gary Igor Dmitrienko	CEPHALOSPORIN DERIVATIVES AS BETA LACTAMASE HEMMER AND COMPOSITIONS THEREFOR AND METHOD FOR THEIR USE
GB201818410D0 (en) *	2018-11-12	2018-12-26	Imperial Innovations Ltd	Compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3641021A (en) *	1969-04-18	1972-02-08	Lilly Co Eli	3 7-(ring-substituted) cephalosporin compounds
JPS5116436B1 (es) *	1971-05-31	1976-05-24
JPS5143785A (en) *	1974-10-11	1976-04-14	Yamanouchi Pharma Co Ltd	Shinsefuarosuhorinkanrenkagobutsuno goseiho
JPS612674B2 (es) *	1974-06-20	1986-01-27	Meiji Seika Co
CA1100129A (en) *	1974-08-02	1981-04-28	William H.W. Lunn	Cephalosporin compounds
FI761035A (es) *	1975-04-21	1976-10-22	Erba Carlo Spa

1978
- 1978-03-02 CY CY1196A patent/CY1196A/xx unknown
- 1978-03-02 GB GB8224/78A patent/GB1597036A/en not_active Expired
- 1978-03-02 CA CA298,070A patent/CA1083141A/en not_active Expired
- 1978-03-02 IL IL54181A patent/IL54181A/xx unknown
- 1978-03-02 DE DE19782809058 patent/DE2809058A1/de active Granted
- 1978-03-02 PT PT67732A patent/PT67732A/pt unknown
- 1978-03-02 AT AT0150778A patent/AT366696B/de not_active IP Right Cessation
- 1978-03-02 NZ NZ186610A patent/NZ186610A/xx unknown
- 1978-03-03 PH PH20847A patent/PH14596A/en unknown
- 1978-03-03 GR GR55608A patent/GR68893B/el unknown
- 1978-03-03 FI FI780716A patent/FI69309C/fi not_active IP Right Cessation
- 1978-03-03 CH CH236178A patent/CH637964A5/de not_active IP Right Cessation
- 1978-03-03 AU AU33828/78A patent/AU515428B2/en not_active Expired
- 1978-03-03 DK DK97378A patent/DK97378A/da not_active Application Discontinuation
- 1978-03-03 NL NL7802376A patent/NL190703C/xx not_active IP Right Cessation
- 1978-03-03 HU HU78EI784A patent/HU179967B/hu unknown
- 1978-03-03 FR FR7806158A patent/FR2383189A1/fr active Granted
- 1978-03-06 YU YU00514/78A patent/YU51478A/xx unknown
- 1978-03-06 SE SE7802530A patent/SE437991B/sv not_active IP Right Cessation
- 1978-03-06 MX MX786901U patent/MX5142E/es unknown
- 1978-03-06 IE IE453/78A patent/IE46437B1/en not_active IP Right Cessation
- 1978-03-06 IT IT20912/78A patent/IT1093504B/it active
- 1978-03-07 BG BG7838941A patent/BG31379A3/xx unknown
- 1978-03-07 PL PL1978205135A patent/PL122152B1/pl unknown
- 1978-03-07 ES ES467637A patent/ES467637A1/es not_active Expired
- 1978-03-07 JP JP2646878A patent/JPS53130689A/ja active Granted
- 1978-03-07 CS CS781436A patent/CS205115B2/cs unknown
- 1978-03-07 DD DD78204007A patent/DD137356A5/xx not_active IP Right Cessation
- 1978-03-07 EG EG149/78A patent/EG13454A/xx active
1983
- 1983-10-27 HK HK490/83A patent/HK49083A/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
MX5142E (es)	1983-03-30
GR68893B (es)	1982-03-15
NL7802376A (nl)	1978-09-11
GB1597036A (en)	1981-09-03
NZ186610A (en)	1979-11-01
SE7802530L (sv)	1978-09-08
NL190703B (nl)	1994-02-01
PL205135A1 (pl)	1979-06-04
CA1083141A (en)	1980-08-05
FI69309B (fi)	1985-09-30
IE46437B1 (en)	1983-06-15
JPH025758B2 (es)	1990-02-05
HK49083A (en)	1983-11-04
AT366696B (de)	1982-04-26
DE2809058A1 (de)	1978-09-14
CY1196A (en)	1983-12-31
DD137356A5 (de)	1979-08-29
DK97378A (da)	1978-09-08
NL190703C (nl)	1994-07-01
SE437991B (sv)	1985-03-25
JPS53130689A (en)	1978-11-14
IT1093504B (it)	1985-07-19
IL54181A (en)	1981-03-31
CS205115B2 (en)	1981-04-30
IT7820912A0 (it)	1978-03-06
DE2809058C2 (es)	1989-02-09
PH14596A (en)	1981-10-02
FR2383189B1 (es)	1981-06-26
IL54181A0 (en)	1978-06-15
FR2383189A1 (fr)	1978-10-06
YU51478A (en)	1982-10-31
PT67732A (en)	1978-04-01
ATA150778A (de)	1981-09-15
FI69309C (fi)	1986-01-10
BG31379A3 (en)	1981-12-15
ES467637A1 (es)	1980-04-01
EG13454A (en)	1981-12-31
IE780453L (en)	1978-09-07
AU3382878A (en)	1979-09-06
AU515428B2 (en)	1981-04-02
CH637964A5 (en)	1983-08-31
PL122152B1 (en)	1982-06-30
FI780716A (fi)	1978-09-08

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Legal Events

Date	Code	Title	Description
1990-06-28	HU90	Patent valid on 900628