HRP20030030A2 - 3-indolyl-4-phenyl-1h-pyrrole-2,5-dione derivatives as inhibitors of glycogen synthase kinase-3- beta - Google Patents
3-indolyl-4-phenyl-1h-pyrrole-2,5-dione derivatives as inhibitors of glycogen synthase kinase-3- betaInfo
- Publication number
- HRP20030030A2 HRP20030030A2 HR20030030A HRP20030030A HRP20030030A2 HR P20030030 A2 HRP20030030 A2 HR P20030030A2 HR 20030030 A HR20030030 A HR 20030030A HR P20030030 A HRP20030030 A HR P20030030A HR P20030030 A2 HRP20030030 A2 HR P20030030A2
- Authority
- HR
- Croatia
- Prior art keywords
- heteroalkyl
- compound according
- hydrogen
- compound
- alkyl
- Prior art date
Links
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- 108010051975 Glycogen Synthase Kinase 3 beta Proteins 0.000 title claims description 47
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Classifications
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
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- Diabetes (AREA)
- Neurology (AREA)
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- Neurosurgery (AREA)
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- Biomedical Technology (AREA)
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- Obesity (AREA)
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- Cardiology (AREA)
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- Heart & Thoracic Surgery (AREA)
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- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Otolaryngology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US22105800P | 2000-07-27 | 2000-07-27 | |
PCT/EP2001/008293 WO2002010158A2 (en) | 2000-07-27 | 2001-07-18 | 3-indolyl-4-phenyl-1h-pyrrole-2,5-dione derivatives as inhibitors of glycogen synthase kinase-3beta |
Publications (1)
Publication Number | Publication Date |
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HRP20030030A2 true HRP20030030A2 (en) | 2005-02-28 |
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HR20030030A HRP20030030A2 (en) | 2000-07-27 | 2003-01-17 | 3-indolyl-4-phenyl-1h-pyrrole-2,5-dione derivatives as inhibitors of glycogen synthase kinase-3- beta |
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US (2) | US6479490B2 (no) |
EP (1) | EP1307447B1 (no) |
JP (1) | JP3984157B2 (no) |
KR (1) | KR20030017655A (no) |
CN (1) | CN1185229C (no) |
AR (1) | AR033989A1 (no) |
AT (1) | ATE284885T1 (no) |
AU (1) | AU2001293702A1 (no) |
BR (1) | BR0112965A (no) |
CA (1) | CA2417277A1 (no) |
CZ (1) | CZ2003555A3 (no) |
DE (1) | DE60107857T2 (no) |
EC (1) | ECSP034452A (no) |
ES (1) | ES2233691T3 (no) |
GT (1) | GT200100151A (no) |
HK (1) | HK1058670A1 (no) |
HR (1) | HRP20030030A2 (no) |
HU (1) | HUP0301431A2 (no) |
IL (1) | IL153851A0 (no) |
JO (1) | JO2293B1 (no) |
MA (1) | MA26936A1 (no) |
MX (1) | MXPA03000695A (no) |
NO (1) | NO20030328D0 (no) |
NZ (1) | NZ523462A (no) |
PA (1) | PA8523001A1 (no) |
PE (1) | PE20020338A1 (no) |
PL (1) | PL366701A1 (no) |
RU (1) | RU2003104796A (no) |
UY (1) | UY26857A1 (no) |
WO (1) | WO2002010158A2 (no) |
YU (1) | YU4403A (no) |
ZA (1) | ZA200300216B (no) |
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EP1224932A4 (en) * | 1999-08-20 | 2002-10-16 | Sagami Chem Res | DRUGS INHIBITING CELL DEATH |
IL155174A0 (en) * | 2000-10-02 | 2003-10-31 | Reddy Us Therapeutics Inc | Methods and compositions for the treatment of inflammatory diseases |
DE60140201D1 (en) * | 2000-11-07 | 2009-11-26 | Novartis Ag | Indolylmaleimidderivative als proteinkinase-c-inhibitoren |
US6645970B2 (en) * | 2000-11-07 | 2003-11-11 | Novartis Ag | Indolylmaleimide derivatives |
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GB9828640D0 (en) * | 1998-12-23 | 1999-02-17 | Smithkline Beecham Plc | Novel method and compounds |
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