HRP20020234A2 - Use of retigabin for treating neuropathic pain - Google Patents

Use of retigabin for treating neuropathic pain Download PDF

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Publication number
HRP20020234A2
HRP20020234A2 HR20020234A HRP20020234A HRP20020234A2 HR P20020234 A2 HRP20020234 A2 HR P20020234A2 HR 20020234 A HR20020234 A HR 20020234A HR P20020234 A HRP20020234 A HR P20020234A HR P20020234 A2 HRP20020234 A2 HR P20020234A2
Authority
HR
Croatia
Prior art keywords
pain
hyperalgesia
neuropathic pain
treatment
nerve
Prior art date
Application number
HR20020234A
Other languages
English (en)
Croatian (hr)
Inventor
Chris Rundfeldt
Reni Bartsch
Angelika Rostock
Christine Tober
Rita Dost
Original Assignee
Viatris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viatris Gmbh filed Critical Viatris Gmbh
Publication of HRP20020234A2 publication Critical patent/HRP20020234A2/hr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
HR20020234A 1999-09-27 2002-03-18 Use of retigabin for treating neuropathic pain HRP20020234A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/406,135 US6117900A (en) 1999-09-27 1999-09-27 Use of retigabine for the treatment of neuropathic pain
PCT/EP2000/009284 WO2001022953A2 (de) 1999-09-27 2000-09-22 Verwendung von retigabin zur behandlung von neuropathischen schmerzen

Publications (1)

Publication Number Publication Date
HRP20020234A2 true HRP20020234A2 (en) 2003-06-30

Family

ID=23606675

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20020234A HRP20020234A2 (en) 1999-09-27 2002-03-18 Use of retigabin for treating neuropathic pain

Country Status (35)

Country Link
US (1) US6117900A (sr)
EP (1) EP1223927B1 (sr)
JP (1) JP2003510273A (sr)
KR (1) KR100730829B1 (sr)
CN (2) CN100522155C (sr)
AR (1) AR026163A1 (sr)
AT (1) ATE288748T1 (sr)
AU (1) AU777764B2 (sr)
BG (1) BG65795B1 (sr)
BR (1) BR0014293A (sr)
CA (2) CA2659048A1 (sr)
CZ (1) CZ295980B6 (sr)
DE (1) DE50009504D1 (sr)
DK (1) DK1223927T3 (sr)
EE (1) EE05073B1 (sr)
ES (1) ES2237461T3 (sr)
HK (1) HK1052471A1 (sr)
HR (1) HRP20020234A2 (sr)
HU (1) HUP0202853A3 (sr)
IL (3) IL148309A0 (sr)
IS (1) IS6303A (sr)
MX (1) MXPA02003179A (sr)
NO (1) NO329744B1 (sr)
NZ (1) NZ517616A (sr)
PL (1) PL200847B1 (sr)
PT (1) PT1223927E (sr)
RS (1) RS50091B (sr)
RU (1) RU2264813C2 (sr)
SI (1) SI1223927T1 (sr)
SK (1) SK286057B6 (sr)
TR (1) TR200200706T2 (sr)
TW (1) TWI257304B (sr)
UA (1) UA72550C2 (sr)
WO (1) WO2001022953A2 (sr)
ZA (1) ZA200202449B (sr)

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WO2002061075A1 (fr) * 2001-02-01 2002-08-08 Takeda Chemical Industries, Ltd. Proteine de recepteur couple aux proteines g et adn correspondant
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AU2003296954A1 (en) * 2002-12-13 2004-07-09 The Regents Of The University Of California Analgesic combination comprising nalbuphine
ATE357438T1 (de) 2002-12-27 2007-04-15 Lundbeck & Co As H 1,2,4-triaminobenzolderivate zur behandlung von erkrankungen des zentralnervensystems
UA79666C2 (en) * 2002-12-27 2007-07-10 Lundbeck & Co As H 1,2,4-triaminobenzene derivatives suitable for the treatment of the central nervous system disorders
WO2004096767A1 (en) * 2003-04-25 2004-11-11 H. Lundbeck A/S Sustituted indoline and indole derivatives
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TWI349666B (en) 2004-03-12 2011-10-01 Lundbeck & Co As H Substituted morpholine and thiomorpholine derivatives
EP2298766B1 (en) 2005-03-03 2013-09-18 H. Lundbeck A/S Pharmaceutical formulations comrpising a substituted pyridine derivative
US7960436B2 (en) * 2006-06-05 2011-06-14 Valeant Pharmaceuticals International Substituted arylamino-1,2,3,4-tetrahydro naphthalenes and-2,3-dihydro-1H-indenes as potassium channel modulators
US20080045534A1 (en) * 2006-08-18 2008-02-21 Valeant Pharmaceuticals North America Derivatives of 1,3-diamino benzene as potassium channel modulators
CN101563085A (zh) * 2006-08-23 2009-10-21 威朗国际制药公司 作为钾通道调节剂的4-(n-氮杂环烷基)酰苯胺的衍生物
US8993593B2 (en) * 2006-08-23 2015-03-31 Valeant Pharmaceuticals International N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators
US8722929B2 (en) * 2006-10-10 2014-05-13 Valeant Pharmaceuticals International N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators
WO2008066900A1 (en) * 2006-11-28 2008-06-05 Valeant Pharmaceuticals International 1,4 diamino bicyclic retigabine analogues as potassium channel modulators
US8367684B2 (en) * 2007-06-13 2013-02-05 Valeant Pharmaceuticals International Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators
US8563566B2 (en) * 2007-08-01 2013-10-22 Valeant Pharmaceuticals International Naphthyridine derivatives as potassium channel modulators
US7786146B2 (en) * 2007-08-13 2010-08-31 Valeant Pharmaceuticals International Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators
CN101868443A (zh) * 2007-09-20 2010-10-20 特拉维夫大学拉莫特有限公司 N-苯基邻氨基苯甲酸衍生物及其用途
US20100323016A1 (en) * 2008-07-18 2010-12-23 Biljana Nadjsombati Modified release formulation and methods of use
US20100323015A1 (en) * 2008-07-18 2010-12-23 Biljana Nadjsombati Modified release formulation and methods of use
US20100120906A1 (en) * 2008-07-18 2010-05-13 Valeant Pharmaceuticals International Modified release formulation and methods of use
DE102009013613A1 (de) 2009-03-17 2010-09-23 Ratiopharm Gmbh Trockenverarbeitung von Retigabin
DE102009013612A1 (de) 2009-03-17 2010-09-23 Ratiopharm Gmbh Retigabin-Tabletten, bevorzugt mit modifizierter Freisetzung
DE102009013611A1 (de) 2009-03-17 2010-09-23 Ratiopharm Gmbh Festes Retigabin in nicht-kristalliner Form
IT1398282B1 (it) * 2009-07-30 2013-02-22 Difass S A Ora Farmapros S P A Composizione comprendente acido alfa-lipoico e carnosina per il trattamento della sindrome dell arto fantasma
US20110087650A1 (en) * 2009-10-06 2011-04-14 Johnson Controls Technology Company Creation and use of causal relationship models in building management systems and applications
TR201002473A2 (tr) * 2010-03-31 2011-09-21 Mustafa Nevzat �La� Sanay�� A.�. Herpes zoster hastalığının bır opiat reseptör antagonist kullanılarak tedavi yöntemi.
RU2446795C1 (ru) * 2011-03-31 2012-04-10 Федеральное государственное учреждение "Московский научно-исследовательский онкологический институт им. П.А. Герцена Министерства здравоохранения и социального развития Российской Федерации" ФГУ "МНИОИ им. П.А. Герцена "Минздравсоцразвития России" Способ предотвращения фантомного болевого синдрома после ампутации конечностей
CN102531966B (zh) * 2011-12-23 2013-07-24 山东创新药物研发有限公司 瑞替加滨的晶型d及其制备方法
US9345689B2 (en) * 2012-05-18 2016-05-24 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N, N-dimethyl-4-phenyl-4,9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and an anticonvulsant
US20130310385A1 (en) 2012-05-18 2013-11-21 Gruenenthal Gmbh Pharmaceutical Composition Comprising (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine and Antidepressants
US9320725B2 (en) 2012-05-18 2016-04-26 Gruenenthal Gmbh Pharmaceutical composition comprising (1r,4r)-6′-fluoro-N,N-dimethyl-4-phenyl-4′9′-dihydro-3′H-spiro[cyclohexane-1,1′-pyrano[3,4,b]indol]-4-amine and a gabapentinoid
CN103271899A (zh) * 2012-12-30 2013-09-04 北京阜康仁生物制药科技有限公司 瑞替加滨粉碎粒度在制剂中的应用
CN105919990A (zh) * 2016-06-29 2016-09-07 青岛云天生物技术有限公司 用于预防和治疗神经病理性疼痛的药物组合物及其用途
CN106176715A (zh) * 2016-06-29 2016-12-07 青岛云天生物技术有限公司 一种神经病理性疼痛治疗用药物组合物及其用途
WO2019014547A1 (en) 2017-07-14 2019-01-17 Texas Tech University System FUNCTIONALIZED PYRIDINE CARBAMATES HAVING ENHANCED NEUROPROTECTOR ACTIVITY

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Also Published As

Publication number Publication date
TR200200706T2 (tr) 2002-10-21
HUP0202853A3 (en) 2003-10-28
NO20021418L (no) 2002-03-21
RS50091B (sr) 2009-01-22
BG65795B1 (bg) 2009-12-31
MXPA02003179A (es) 2003-08-20
EP1223927A2 (de) 2002-07-24
JP2003510273A (ja) 2003-03-18
SK2922002A3 (en) 2002-08-06
DE50009504D1 (de) 2005-03-17
WO2001022953A3 (de) 2002-05-23
PL353393A1 (en) 2003-11-17
ATE288748T1 (de) 2005-02-15
BG106450A (en) 2002-09-30
CN100522155C (zh) 2009-08-05
ES2237461T3 (es) 2005-08-01
CA2384504A1 (en) 2001-04-05
EE05073B1 (et) 2008-10-15
CA2659048A1 (en) 2001-04-05
IL148309A0 (en) 2002-09-12
KR100730829B1 (ko) 2007-06-20
IS6303A (is) 2002-03-18
IL187030A0 (en) 2008-02-09
KR20020042691A (ko) 2002-06-05
NO329744B1 (no) 2010-12-13
RU2002109240A (ru) 2004-01-10
ZA200202449B (en) 2003-03-26
AU7906100A (en) 2001-04-30
NZ517616A (en) 2002-12-20
UA72550C2 (en) 2005-03-15
SI1223927T1 (sr) 2005-08-31
US6117900A (en) 2000-09-12
CA2384504C (en) 2009-05-26
CZ295980B6 (cs) 2005-12-14
EP1223927B1 (de) 2005-02-09
EE200200145A (et) 2003-04-15
PT1223927E (pt) 2005-06-30
AU777764B2 (en) 2004-10-28
CN101444498A (zh) 2009-06-03
IL187030A (en) 2011-06-30
TWI257304B (en) 2006-07-01
WO2001022953A2 (de) 2001-04-05
HUP0202853A2 (hu) 2002-12-28
BR0014293A (pt) 2002-05-21
SK286057B6 (sk) 2008-02-05
AR026163A1 (es) 2003-01-29
CZ2002989A3 (cs) 2002-08-14
HK1052471A1 (zh) 2003-09-19
PL200847B1 (pl) 2009-02-27
CN1409632A (zh) 2003-04-09
YU20302A (sh) 2005-03-15
RU2264813C2 (ru) 2005-11-27
DK1223927T3 (da) 2005-04-11
NO20021418D0 (no) 2002-03-21
IL148309A (en) 2007-12-03

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