HK1044483A1 - Il-8受體拮抗劑 - Google Patents

Il-8受體拮抗劑

Info

Publication number: HK1044483A1
Authority: HK; Hong Kong
Prior art keywords: receptor antagonists; antagonists; receptor
Prior art date: 1999-06-16

Application number

HK02106188.7A

Other languages

English (en)

Inventor

Martin Benson Gregory

P Hertzberg Robert

J Jurewicz Anthony

Clarence Rutledge Melvin

F Veber Daniel

L Widdowson Katherine

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-06-16

Filing date

2002-08-22

Publication date

2002-10-25

2002-08-22 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

2002-10-25 Publication of HK1044483A1 publication Critical patent/HK1044483A1/zh

Links

102000010681 interleukin-8 receptors Human genes 0.000 title 1
108010038415 interleukin-8 receptors Proteins 0.000 title 1
239000002464 receptor antagonist Substances 0.000 title 1
229940044551 receptor antagonist Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Physical Education & Sports Medicine (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Epidemiology (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Molecular Biology (AREA)
Tropical Medicine & Parasitology (AREA)
Vascular Medicine (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Urology & Nephrology (AREA)
Biotechnology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Cardiology (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Quinoline Compounds (AREA)

HK02106188.7A 1999-06-16 2002-08-22 Il-8受體拮抗劑 HK1044483A1 (zh)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US13967599P	1999-06-16	1999-06-16
PCT/US2000/016499 WO2000076495A1 (en)	1999-06-16	2000-06-15	Il-8 receptor antagonists

Publications (1)

Publication Number	Publication Date
HK1044483A1 true HK1044483A1 (zh)	2002-10-25

Family

ID=22487790

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK02106188.7A HK1044483A1 (zh)	1999-06-16	2002-08-22	Il-8受體拮抗劑

Country Status (20)

Country	Link
EP (1)	EP1185261A4 (zh)
JP (1)	JP2003501459A (zh)
KR (1)	KR20020010709A (zh)
CN (1)	CN1355697A (zh)
AR (1)	AR030391A1 (zh)
AU (1)	AU766083B2 (zh)
BR (1)	BR0010802A (zh)
CA (1)	CA2377341A1 (zh)
CO (1)	CO5200760A1 (zh)
CZ (1)	CZ20014471A3 (zh)
HK (1)	HK1044483A1 (zh)
HU (1)	HUP0201571A3 (zh)
IL (1)	IL145761A0 (zh)
MX (1)	MXPA01013004A (zh)
NO (1)	NO20016053D0 (zh)
NZ (1)	NZ514695A (zh)
PL (1)	PL352232A1 (zh)
TR (1)	TR200103680T2 (zh)
WO (1)	WO2000076495A1 (zh)
ZA (1)	ZA200109479B (zh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7521479B2 (en) *	2001-04-16	2009-04-21	Panacea Pharmaceuticals, Inc.	Methods of treating prion disease in mammals
GB0201882D0 (en) *	2002-01-28	2002-03-13	Novartis Ag	Organic compounds
US20060058395A1 (en) *	2002-08-01	2006-03-16	Neurosearch A/S	Compounds useful for the treatment of diseases responsive to antiangiogenetic therapy
US7550499B2 (en)	2004-05-12	2009-06-23	Bristol-Myers Squibb Company	Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
AU2005245399A1 (en) *	2004-05-12	2005-12-01	Schering Corporation	CXCR1 and CXCR2 chemokine antagonists
TW200600492A (en)	2004-05-18	2006-01-01	Achillion Pharmaceuticals Inc	Substituted aryl acylthioureas and related compounds; inhibitors of viral replication
JP2008517930A (ja)	2004-10-21	2008-05-29	トランステックファーマ，インコーポレイテッド	ＧａｌＲ１のアゴニストとしてのビススルホンアミド化合物、組成物、及び使用法
EP1954696B1 (en)	2005-01-19	2011-02-23	Bristol-Myers Squibb Company	2-phenoxy-n-(1,3,4-thiadizol-2-yl)pyridin-3-amine derivatives and related compounds as p2y1 receptor inhibitors for the treatment of thromboembolic disorders
WO2006089871A2 (en) *	2005-02-23	2006-08-31	Neurosearch A/S	Diphenylurea derivatives useful as erg channel openers for the treatment of cardiac arrhythmias
US7714002B2 (en)	2005-06-27	2010-05-11	Bristol-Myers Squibb Company	Carbocycle and heterocycle antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
WO2007002584A1 (en)	2005-06-27	2007-01-04	Bristol-Myers Squibb Company	Linear urea mimics antagonists of p2y1 receptor useful in the treatment of thrombotic conditions
ES2352796T3 (es)	2005-06-27	2011-02-23	Bristol-Myers Squibb Company	Antagonistas cíclicos unidos a c del receptor p2y1 útiles en el tratamiento de afecciones trombóticas.
EP1896466B1 (en)	2005-06-27	2011-04-13	Bristol-Myers Squibb Company	N-linked heterocyclic antagonists of p2y1 receptor useful in the treatment of thrombotic conditions
US7960569B2 (en)	2006-10-17	2011-06-14	Bristol-Myers Squibb Company	Indole antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
JP2008184403A (ja) *	2007-01-29	2008-08-14	Japan Health Science Foundation	新規ｃ型肝炎ウイルス阻害剤
KR100982661B1 (ko) *	2008-04-22	2010-09-17	전남대학교산학협력단	플라스멥신 ⅱ 활성을 저해하는 화합물을 유효성분으로함유하는 말라리아 예방 및 치료를 위한 약학 조성물 및이를 이용한 말라리아 치료방법
KR100970940B1 (ko) *	2010-05-03	2010-07-20	전남대학교산학협력단	플라스멥신 ⅱ 활성을 저해하는 화합물을 유효성분으로 함유하는 말라리아 예방 및 치료를 위한 약학 조성물 및 이를 이용한 말라리아 치료방법
US10093617B1 (en) *	2015-10-30	2018-10-09	Sumitomo Chemical Company, Limited	Method for producing 2-amino-4-substituted phenol

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA921120B (en) *	1991-02-19	1993-01-27	Smithkline Beecham Corp	Cytokine inhibitors
JPH11503110A (ja) *	1995-02-17	1999-03-23	スミスクライン・ビーチャム・コーポレイション	Ｉｌ−８受容体拮抗剤
WO2000016768A1 (en) *	1998-09-18	2000-03-30	Smithkline Beecham Corporation	Cxcr2 inhibitors and pmn adhesion and t-cell chemotaxis

2000
- 2000-06-13 CO CO00043844A patent/CO5200760A1/es not_active Application Discontinuation
- 2000-06-14 AR ARP000102923A patent/AR030391A1/es not_active Application Discontinuation
- 2000-06-15 IL IL14576100A patent/IL145761A0/xx unknown
- 2000-06-15 PL PL00352232A patent/PL352232A1/xx not_active Application Discontinuation
- 2000-06-15 NZ NZ514695A patent/NZ514695A/en unknown
- 2000-06-15 CA CA002377341A patent/CA2377341A1/en not_active Abandoned
- 2000-06-15 JP JP2001502828A patent/JP2003501459A/ja not_active Withdrawn
- 2000-06-15 HU HU0201571A patent/HUP0201571A3/hu unknown
- 2000-06-15 WO PCT/US2000/016499 patent/WO2000076495A1/en not_active Application Discontinuation
- 2000-06-15 CN CN00809045A patent/CN1355697A/zh active Pending
- 2000-06-15 AU AU57413/00A patent/AU766083B2/en not_active Ceased
- 2000-06-15 TR TR2001/03680T patent/TR200103680T2/xx unknown
- 2000-06-15 EP EP00942843A patent/EP1185261A4/en not_active Withdrawn
- 2000-06-15 CZ CZ20014471A patent/CZ20014471A3/cs unknown
- 2000-06-15 KR KR1020017016142A patent/KR20020010709A/ko not_active Application Discontinuation
- 2000-06-15 BR BR0010802-2A patent/BR0010802A/pt not_active IP Right Cessation
- 2000-06-15 MX MXPA01013004A patent/MXPA01013004A/es unknown
2001
- 2001-11-16 ZA ZA200109479A patent/ZA200109479B/en unknown
- 2001-12-11 NO NO20016053A patent/NO20016053D0/no not_active Application Discontinuation
2002
- 2002-08-22 HK HK02106188.7A patent/HK1044483A1/zh unknown

Also Published As

Publication number	Publication date
CO5200760A1 (es)	2002-09-27
PL352232A1 (en)	2003-08-11
CZ20014471A3 (cs)	2002-08-14
BR0010802A (pt)	2002-02-19
TR200103680T2 (tr)	2002-07-22
KR20020010709A (ko)	2002-02-04
JP2003501459A (ja)	2003-01-14
AU5741300A (en)	2001-01-02
CN1355697A (zh)	2002-06-26
HUP0201571A2 (en)	2002-08-28
IL145761A0 (en)	2002-07-25
CA2377341A1 (en)	2000-12-21
MXPA01013004A (es)	2002-07-30
NZ514695A (en)	2004-05-28
NO20016053L (no)	2001-12-11
WO2000076495A1 (en)	2000-12-21
NO20016053D0 (no)	2001-12-11
EP1185261A1 (en)	2002-03-13
HUP0201571A3 (en)	2002-11-28
EP1185261A4 (en)	2004-02-25
AR030391A1 (es)	2003-08-20
AU766083B2 (en)	2003-10-09
ZA200109479B (en)	2002-11-18

Publication	Publication Date	Title
PL352232A1 (en)	2003-08-11	Il-8 receptor antagonists
DZ3309A1 (en)	2001-09-07	Il-8 receptor antagonists
AU4560601A (en)	2001-09-24	Il-8 receptor antagonists
IL145762A0 (en)	2002-07-25	Il-8 receptor antagonists
IL146046A0 (en)	2002-07-25	Il-8 receptor antagonists
AP2002002599A0 (en)	2002-09-30	Il-8 receptor antagonists
IL146053A0 (en)	2002-07-25	Il-8 receptor antagonists
EP1039903A4 (en)	2001-12-05	INTERLEUKIN-8 RECEPTOR ANTAGONISTS
EP1047424A4 (en)	2002-05-22	IL-8 RECEPTOR ANTAGONISTS
HK1044717A1 (zh)	2002-11-01	Il-8受體拮抗劑
EP1261329A4 (en)	2005-08-17	IL-8 RECEPTOR ANTAGONISTS
HK1044475A1 (zh)	2002-10-25	Il-8受體拮抗劑
PL352218A1 (en)	2003-08-11	Il-8 receptor antagonists
HUP0202004A2 (en)	2002-10-28	Il-8 receptor antagonists
IL140983A0 (en)	2002-02-10	Il-8 receptor antagonists
EP1237548A4 (en)	2003-07-23	IL-8 RECEPTOR ANTAGONISTS
ZA985813B (en)	1999-03-31	IL-8 receptor antagonists
ZA985975B (en)	1999-01-07	IL-8 receptor antagonists
EP1087661A4 (en)	2003-04-16	IL-8 RECEPTOR ANTAGONISTS
EP1121360A4 (en)	2002-01-23	INTERLEUKIN-8 (IL-8) RECEPTOR ANTAGONISTS