PL352232A1 - Il-8 receptor antagonists - Google Patents

Il-8 receptor antagonists

Info

Publication number: PL352232A1
Authority: PL; Poland
Prior art keywords: receptor antagonists; antagonists; receptor
Prior art date: 1999-06-16

Application number

PL00352232A

Inventor

Katherine L Widdowson

Daniel F Veber

Anthony J Jurewicz

Melvin C Rutledge

Robert P Hertzberg

Gregory M Benson

Original Assignee

Smithkline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-06-16

Filing date

2000-06-15

Publication date

2003-08-11

2000-06-15 Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp

2003-08-11 Publication of PL352232A1 publication Critical patent/PL352232A1/en

Links

102000010681 interleukin-8 receptors Human genes 0.000 title 1
108010038415 interleukin-8 receptors Proteins 0.000 title 1
239000002464 receptor antagonist Substances 0.000 title 1
229940044551 receptor antagonist Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Physical Education & Sports Medicine (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Epidemiology (AREA)
Rheumatology (AREA)
Orthopedic Medicine & Surgery (AREA)
Tropical Medicine & Parasitology (AREA)
Hematology (AREA)
Pulmonology (AREA)
Biotechnology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Diabetes (AREA)
Emergency Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Quinoline Compounds (AREA)

PL00352232A 1999-06-16 2000-06-15 Il-8 receptor antagonists PL352232A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US13967599P	1999-06-16	1999-06-16

Publications (1)

Publication Number	Publication Date
PL352232A1 true PL352232A1 (en)	2003-08-11

Family

ID=22487790

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL00352232A PL352232A1 (en)	1999-06-16	2000-06-15	Il-8 receptor antagonists

Country Status (20)

Country	Link
EP (1)	EP1185261A4 (en)
JP (1)	JP2003501459A (en)
KR (1)	KR20020010709A (en)
CN (1)	CN1355697A (en)
AR (1)	AR030391A1 (en)
AU (1)	AU766083B2 (en)
BR (1)	BR0010802A (en)
CA (1)	CA2377341A1 (en)
CO (1)	CO5200760A1 (en)
CZ (1)	CZ20014471A3 (en)
HK (1)	HK1044483A1 (en)
HU (1)	HUP0201571A3 (en)
IL (1)	IL145761A0 (en)
MX (1)	MXPA01013004A (en)
NO (1)	NO20016053D0 (en)
NZ (1)	NZ514695A (en)
PL (1)	PL352232A1 (en)
TR (1)	TR200103680T2 (en)
WO (1)	WO2000076495A1 (en)
ZA (1)	ZA200109479B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7521479B2 (en) *	2001-04-16	2009-04-21	Panacea Pharmaceuticals, Inc.	Methods of treating prion disease in mammals
GB0201882D0 (en) *	2002-01-28	2002-03-13	Novartis Ag	Organic compounds
JP2005537336A (en) *	2002-08-01	2005-12-08	ニューロサーチ、アクティーゼルスカブ	Compounds useful in the treatment of diseases that respond to anti-angiogenic treatment
JP2007537272A (en) *	2004-05-12	2007-12-20	シェーリング　コーポレイション	CXCR1 and CXCR2 chemokine antagonists
US7550499B2 (en)	2004-05-12	2009-06-23	Bristol-Myers Squibb Company	Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
TW200600492A (en) *	2004-05-18	2006-01-01	Achillion Pharmaceuticals Inc	Substituted aryl acylthioureas and related compounds; inhibitors of viral replication
EP1809619A1 (en)	2004-10-21	2007-07-25	Transtech Pharma, Inc.	Bissulfonamide compounds as agonists of galr1, compositions, and methods of use
WO2006078621A2 (en)	2005-01-19	2006-07-27	Bristol-Myers Squibb Company	2-phenoxy-n- (1, 3 , 4-thiadizol-2-yl) pyridin-3-amine derivatives and related compounds as p2y1 receptor inhibitors for the treatment of thromboembolic disorders
WO2006089871A2 (en) *	2005-02-23	2006-08-31	Neurosearch A/S	Diphenylurea derivatives useful as erg channel openers for the treatment of cardiac arrhythmias
AU2006261828A1 (en)	2005-06-27	2007-01-04	Bristol-Myers Squibb Company	N-linked heterocyclic antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
WO2007002634A1 (en)	2005-06-27	2007-01-04	Bristol-Myers Squibb Company	Carbocycle and heterocycle antagonists of p2y1 receptor useful in the treatment of thrombotic conditions
ATE502924T1 (en)	2005-06-27	2011-04-15	Bristol Myers Squibb Co	LINEAR UREA MIMETIC ANTAGONISTS OF THE P2Y1 RECEPTOR FOR THE TREATMENT OF THROMBOSIS
WO2007002635A2 (en)	2005-06-27	2007-01-04	Bristol-Myers Squibb Company	C-linked cyclic antagonists of p2y1 receptor useful in the treatment of thrombotic conditions
US7960569B2 (en)	2006-10-17	2011-06-14	Bristol-Myers Squibb Company	Indole antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions
JP2008184403A (en) *	2007-01-29	2008-08-14	Japan Health Science Foundation	New hepatitis c virus inhibitor
KR100982661B1 (en) *	2008-04-22	2010-09-17	전남대학교산학협력단	Pharmaceutical composition for the prevention and treatment of malaria containing a compound that inhibits plasmincin II activity as an active ingredient and a method for treating malaria using the same
KR100970940B1 (en) *	2010-05-03	2010-07-20	전남대학교산학협력단	Pharmaceutical composition for preventing and treating malaria comprising compounds that inhibit Plasmepsin II activity and the method of treating malaria using thereof
US10093617B1 (en) *	2015-10-30	2018-10-09	Sumitomo Chemical Company, Limited	Method for producing 2-amino-4-substituted phenol

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA921120B (en) *	1991-02-19	1993-01-27	Smithkline Beecham Corp	Cytokine inhibitors
EP0809492A4 (en) *	1995-02-17	2007-01-24	Smithkline Beecham Corp	Il-8 receptor antagonists
WO2000016768A1 (en) *	1998-09-18	2000-03-30	Smithkline Beecham Corporation	Cxcr2 inhibitors and pmn adhesion and t-cell chemotaxis

2000
- 2000-06-13 CO CO00043844A patent/CO5200760A1/en not_active Application Discontinuation
- 2000-06-14 AR ARP000102923A patent/AR030391A1/en not_active Application Discontinuation
- 2000-06-15 EP EP00942843A patent/EP1185261A4/en not_active Withdrawn
- 2000-06-15 MX MXPA01013004A patent/MXPA01013004A/en unknown
- 2000-06-15 HU HU0201571A patent/HUP0201571A3/en unknown
- 2000-06-15 WO PCT/US2000/016499 patent/WO2000076495A1/en not_active Application Discontinuation
- 2000-06-15 CZ CZ20014471A patent/CZ20014471A3/en unknown
- 2000-06-15 KR KR1020017016142A patent/KR20020010709A/en not_active Application Discontinuation
- 2000-06-15 PL PL00352232A patent/PL352232A1/en not_active Application Discontinuation
- 2000-06-15 JP JP2001502828A patent/JP2003501459A/en not_active Withdrawn
- 2000-06-15 AU AU57413/00A patent/AU766083B2/en not_active Ceased
- 2000-06-15 CA CA002377341A patent/CA2377341A1/en not_active Abandoned
- 2000-06-15 IL IL14576100A patent/IL145761A0/en unknown
- 2000-06-15 CN CN00809045A patent/CN1355697A/en active Pending
- 2000-06-15 NZ NZ514695A patent/NZ514695A/en unknown
- 2000-06-15 BR BR0010802-2A patent/BR0010802A/en not_active IP Right Cessation
- 2000-06-15 TR TR2001/03680T patent/TR200103680T2/en unknown
2001
- 2001-11-16 ZA ZA200109479A patent/ZA200109479B/en unknown
- 2001-12-11 NO NO20016053A patent/NO20016053D0/en not_active Application Discontinuation
2002
- 2002-08-22 HK HK02106188.7A patent/HK1044483A1/en unknown

Also Published As

Publication number	Publication date
HK1044483A1 (en)	2002-10-25
AU5741300A (en)	2001-01-02
CA2377341A1 (en)	2000-12-21
NZ514695A (en)	2004-05-28
AU766083B2 (en)	2003-10-09
BR0010802A (en)	2002-02-19
KR20020010709A (en)	2002-02-04
EP1185261A1 (en)	2002-03-13
JP2003501459A (en)	2003-01-14
IL145761A0 (en)	2002-07-25
CO5200760A1 (en)	2002-09-27
HUP0201571A2 (en)	2002-08-28
CZ20014471A3 (en)	2002-08-14
HUP0201571A3 (en)	2002-11-28
NO20016053L (en)	2001-12-11
AR030391A1 (en)	2003-08-20
ZA200109479B (en)	2002-11-18
EP1185261A4 (en)	2004-02-25
MXPA01013004A (en)	2002-07-30
TR200103680T2 (en)	2002-07-22
CN1355697A (en)	2002-06-26
NO20016053D0 (en)	2001-12-11
WO2000076495A1 (en)	2000-12-21

Legal Events

Date	Code	Title	Description
2007-09-28	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)

Publication	Publication Date	Title
PL352232A1 (en)	2003-08-11	Il-8 receptor antagonists
DZ3309A1 (en)	2001-09-07	Il-8 receptor antagonists
AU4560601A (en)	2001-09-24	Il-8 receptor antagonists
IL145762A0 (en)	2002-07-25	Il-8 receptor antagonists
PL351946A1 (en)	2003-07-14	Il-8 receptor antagonists
AP2002002599A0 (en)	2002-09-30	Il-8 receptor antagonists
PL351947A1 (en)	2003-07-14	Il-8 receptor antagonists
EP1039903A4 (en)	2001-12-05	Il-8 receptor antagonists
EP1047424A4 (en)	2002-05-22	Il-8 receptor antagonists
EP1194143A4 (en)	2004-02-04	Il-8 receptor antagonists
EP1261329A4 (en)	2005-08-17	Il-8 receptor antagonists
EP1185270A4 (en)	2004-02-11	Il-8 receptor antagonists
HUP0202004A3 (en)	2003-03-28	Il-8 receptor antagonists
PL352218A1 (en)	2003-08-11	Il-8 receptor antagonists
PL346178A1 (en)	2002-01-28	Il-8 receptor antagonists
EP1237548A4 (en)	2003-07-23	Il-8 receptor antagonists
ZA985975B (en)	1999-01-07	IL-8 receptor antagonists
ZA985813B (en)	1999-03-31	IL-8 receptor antagonists
EP1121360A4 (en)	2002-01-23	Il-8 receptor antagonists
EP1087661A4 (en)	2003-04-16	Il-8 receptor antagonists