GB2116180B - Cephalosporin derivatives - Google Patents

Cephalosporin derivatives

Info

Publication number: GB2116180B
Authority: GB; United Kingdom
Prior art keywords: cephalosporin derivatives; cephalosporin; derivatives
Prior art date: 1982-03-04
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

GB08305940A

Other languages

English (en)

Other versions

GB8305940D0 (en

GB2116180A (en

Inventor

Shimpei Aburaki

Hajime Kamachi

Yukio Narita

Jun Okumura

Takayuki Naito

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bristol Myers Co

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-03-04

Filing date

1983-03-03

Publication date

1985-09-18

1982-03-04 Priority claimed from US06/354,851 external-priority patent/US4406899A/en

1983-03-03 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1983-04-07 Publication of GB8305940D0 publication Critical patent/GB8305940D0/en

1983-09-21 Publication of GB2116180A publication Critical patent/GB2116180A/en

1985-09-18 Application granted granted Critical

1985-09-18 Publication of GB2116180B publication Critical patent/GB2116180B/en

Status Expired legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

GB08305940A 1982-03-04 1983-03-03 Cephalosporin derivatives Expired GB2116180B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/354,851 US4406899A (en)	1982-03-04	1982-03-04	Cephalosporins
US35753482A	1982-03-12	1982-03-12

Publications (3)

Publication Number	Publication Date
GB8305940D0 GB8305940D0 (en)	1983-04-07
GB2116180A GB2116180A (en)	1983-09-21
GB2116180B true GB2116180B (en)	1985-09-18

Family

ID=26998584

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GB08305940A Expired GB2116180B (en)	1982-03-04	1983-03-03	Cephalosporin derivatives

Country Status (29)

Country	Link
KR (1)	KR870001986B1 (de)
AT (2)	AT382155B (de)
AU (1)	AU562776B2 (de)
BE (1)	BE896086A (de)
CA (1)	CA1213882A (de)
CH (1)	CH654313A5 (de)
CS (1)	CS249512B2 (de)
DD (1)	DD210280A5 (de)
DE (1)	DE3307550A1 (de)
DK (1)	DK156900C (de)
EG (1)	EG15934A (de)
ES (2)	ES8403919A1 (de)
FI (1)	FI74973C (de)
FR (1)	FR2522659B1 (de)
GB (1)	GB2116180B (de)
GR (1)	GR77916B (de)
HU (1)	HU193158B (de)
IE (1)	IE56647B1 (de)
IL (1)	IL68011A0 (de)
IT (1)	IT1170307B (de)
LU (1)	LU84674A1 (de)
MY (1)	MY8700943A (de)
NL (2)	NL193284C (de)
NZ (1)	NZ203312A (de)
PH (1)	PH18002A (de)
PT (1)	PT76330B (de)
SE (1)	SE453091B (de)
SU (1)	SU1250173A3 (de)
YU (2)	YU43822B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3409431A1 (de) *	1983-10-08	1985-04-18	Hoechst Ag, 6230 Frankfurt	Cephalosporinderivate und verfahren zu ihrer herstellung
DE3404906A1 (de) *	1984-02-11	1985-08-14	Bayer Ag, 5090 Leverkusen	1-oxadethiacephalosporinderivate sowie verfahren zu ihrer herstellung
DE3419013A1 (de) *	1984-05-22	1985-11-28	Bayer Ag, 5090 Leverkusen	Neue cephalosporine und verfahren zu ihrer herstellung
GB8424692D0 (en) *	1984-10-01	1984-11-07	Glaxo Group Ltd	Chemical compounds
US4698336A (en) *	1985-01-30	1987-10-06	Eisai Co., Ltd.	3-(pyrrolidinio)methyl-3-cephem derivatives
FR2585705B1 (fr) *	1985-08-05	1989-01-13	Bristol Myers Co	Sels de cephalosporine et compositions injectables
US4910301A (en) *	1985-08-05	1990-03-20	Bristol-Myers Company	Cefepime cephalosporin salts
US4808617A (en) *	1985-12-18	1989-02-28	Bristol-Myers Company	Lyophilized or precipitated cephalosporin zwitterion and salt combination
EP0237735B1 (de) *	1986-03-17	1994-03-30	Fujisawa Pharmaceutical Co., Ltd.	3,7-Disubstituierte-3-Cephemverbindungen und Verfahren zu ihrer Herstellung
CA2011116C (en) *	1989-03-06	1999-11-16	Murray A. Kaplan	Lyophilized bmy-28142 dihydrochloride for parenteral use
EP0503453B1 (de)	1991-03-08	2001-05-09	Biochemie Gesellschaft M.B.H.	Verfahren zur Herstellung von Cephalosporinen und Zwischenprodukte in diesem Verfahren
MY108872A (en) *	1991-09-10	1996-11-30	Bristol Myers Squibb Co	Preparation of a cephalosporin antibiotic using the syn-isomer of a thiazolyl intermediate.
YU81692A (sh) *	1991-09-10	1995-03-27	Bristol-Myers Co.	Postupak za proizvodnju cefalosporinskog antibiotika
US5523400A (en) *	1993-04-16	1996-06-04	Hoffmann-La Roche Inc.	Cephalosporin antibiotics
SI1699804T1 (sl) *	2003-12-23	2008-08-31	Sandoz Ag	Postopek za pripravo intermediatov za uporabo pri sintezi cefalosporinov

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2715385A1 (de) *	1976-04-14	1977-11-10	Takeda Chemical Industries Ltd	Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
GB1591439A (en) *	1976-10-01	1981-06-24	Glaxo Operations Ltd	7-syn (oxyimino -acylamido) cephalosporins
AR228726A1 (es) *	1978-05-26	1983-04-15	Glaxo Group Ltd	Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato
NZ191936A (en) *	1978-10-27	1982-09-07	Glaxo Group Ltd	Cephalosporin antibiotics
US4443444A (en) *	1980-08-11	1984-04-17	Fujisawa Pharmaceutical Co., Ltd.	Cephem compounds

1983
- 1983-02-02 CA CA000420788A patent/CA1213882A/en not_active Expired
- 1983-02-10 AU AU11304/83A patent/AU562776B2/en not_active Expired
- 1983-02-16 NZ NZ203312A patent/NZ203312A/en unknown
- 1983-02-24 DK DK086283A patent/DK156900C/da not_active IP Right Cessation
- 1983-02-28 EG EG136/83A patent/EG15934A/xx active
- 1983-02-28 CS CS831295A patent/CS249512B2/cs unknown
- 1983-03-01 FR FR8303334A patent/FR2522659B1/fr not_active Expired
- 1983-03-01 FI FI830689A patent/FI74973C/fi not_active IP Right Cessation
- 1983-03-01 IL IL68011A patent/IL68011A0/xx not_active IP Right Cessation
- 1983-03-01 IT IT47826/83A patent/IT1170307B/it active
- 1983-03-01 NL NL8300755A patent/NL193284C/nl not_active IP Right Cessation
- 1983-03-02 GR GR70653A patent/GR77916B/el unknown
- 1983-03-02 ES ES520224A patent/ES8403919A1/es not_active Expired
- 1983-03-02 PH PH28591A patent/PH18002A/en unknown
- 1983-03-03 DD DD83248457A patent/DD210280A5/de unknown
- 1983-03-03 PT PT76330A patent/PT76330B/pt unknown
- 1983-03-03 SE SE8301178A patent/SE453091B/sv not_active IP Right Cessation
- 1983-03-03 IE IE455/83A patent/IE56647B1/en not_active IP Right Cessation
- 1983-03-03 CH CH1170/83A patent/CH654313A5/de not_active IP Right Cessation
- 1983-03-03 DE DE19833307550 patent/DE3307550A1/de active Granted
- 1983-03-03 HU HU83729A patent/HU193158B/hu unknown
- 1983-03-03 GB GB08305940A patent/GB2116180B/en not_active Expired
- 1983-03-03 SU SU833560801A patent/SU1250173A3/ru active
- 1983-03-04 BE BE0/210263A patent/BE896086A/fr not_active IP Right Cessation
- 1983-03-04 LU LU84674A patent/LU84674A1/fr unknown
- 1983-03-04 YU YU523/83A patent/YU43822B/xx unknown
- 1983-03-04 KR KR1019830000871A patent/KR870001986B1/ko not_active IP Right Cessation
- 1983-03-04 AT AT0076183A patent/AT382155B/de not_active IP Right Cessation
- 1983-10-11 ES ES526397A patent/ES8507557A1/es not_active Expired
1985
- 1985-08-02 AT AT0228285A patent/AT384612B/de not_active IP Right Cessation
- 1985-09-23 YU YU1496/85A patent/YU44777B/xx unknown
1987
- 1987-12-30 MY MY943/87A patent/MY8700943A/xx unknown
1999
- 1999-11-05 NL NL990039C patent/NL990039I2/nl unknown

Also Published As

Publication number	Publication date
NZ203312A (en)	1985-12-13
YU43822B (en)	1989-12-31
DK156900B (da)	1989-10-16
PT76330A (en)	1983-04-01
KR870001986B1 (ko)	1987-10-24
KR840004118A (ko)	1984-10-06
MY8700943A (en)	1987-12-31
FR2522659A1 (fr)	1983-09-09
NL990039I1 (nl)	2000-01-03
AT384612B (de)	1987-12-10
FI74973C (fi)	1988-04-11
SE8301178L (sv)	1983-09-05
PH18002A (en)	1985-02-28
SE8301178D0 (sv)	1983-03-03
DE3307550A1 (de)	1983-09-15
IE830455L (en)	1983-09-04
GR77916B (de)	1984-09-25
ATA228285A (de)	1987-05-15
LU84674A1 (fr)	1983-11-17
SU1250173A3 (ru)	1986-08-07
GB8305940D0 (en)	1983-04-07
NL193284C (nl)	1999-05-06
NL8300755A (nl)	1983-10-03
IT8347826A0 (it)	1983-03-01
CH654313A5 (de)	1986-02-14
ES526397A0 (es)	1985-09-16
ES8507557A1 (es)	1985-09-16
NL193284B (nl)	1999-01-04
GB2116180A (en)	1983-09-21
CS249512B2 (en)	1987-03-12
IE56647B1 (en)	1991-10-23
YU149685A (en)	1986-02-28
BE896086A (fr)	1983-09-05
AU562776B2 (en)	1987-06-18
NL990039I2 (nl)	2000-04-03
AU1130483A (en)	1983-09-08
PT76330B (en)	1986-02-04
ES520224A0 (es)	1984-04-01
FR2522659B1 (fr)	1986-10-24
YU52383A (en)	1986-02-28
FI830689A0 (fi)	1983-03-01
CA1213882A (en)	1986-11-12
FI74973B (fi)	1987-12-31
IT1170307B (it)	1987-06-03
DD210280A5 (de)	1984-06-06
YU44777B (en)	1991-02-28
FI830689L (fi)	1983-09-05
DE3307550C2 (de)	1988-11-24
DK156900C (da)	1990-03-12
IL68011A0 (en)	1983-06-15
SE453091B (sv)	1988-01-11
HU193158B (en)	1987-08-28
ATA76183A (de)	1986-06-15
DK86283A (da)	1983-09-05
EG15934A (en)	1987-10-30
AT382155B (de)	1987-01-26
ES8403919A1 (es)	1984-04-01
DK86283D0 (da)	1983-02-24

Legal Events

Date	Code	Title	Description
2003-03-26	PE20	Patent expired after termination of 20 years	Effective date: 20030302

Publication	Publication Date	Title
GB2134522B (en)	1987-02-25	Cephalosporin derivatives
GB2117770B (en)	1985-10-09	Cephalosporin derivatives
EP0127992A3 (en)	1985-11-21	Cephalosporin derivatives
GB2116180B (en)	1985-09-18	Cephalosporin derivatives
GB8430073D0 (en)	1985-01-09	Cephalosporin derivatives
DE3368638D1 (en)	1987-02-05	Cephalosporin derivatives
GB8409383D0 (en)	1984-05-23	Indolylglycyl cephalosporin derivatives
DE3380813D1 (en)	1989-12-14	Cephalosporin derivatives
GB8409381D0 (en)	1984-05-23	Benzothienylglycyl cephalosporin derivatives
DE3379404D1 (en)	1989-04-20	Cephalosporin derivatives
GB8409382D0 (en)	1984-05-23	Benzothienylglycyl cephalosporin derivatives
DE3379464D1 (en)	1989-04-27	Cephalosporin derivatives
GB8409379D0 (en)	1984-05-23	Naphthylglycyl cephalosporin derivatives
ZA842696B (en)	1985-11-27	Naphthylglycyl cephalosporin derivatives
ZA831887B (en)	1983-11-30	Cephalosporin derivatives
PH19163A (en)	1986-01-16	Cephalosporin derivatives
IE822174L (en)	1983-03-08	Cephalosporin derivatives
IE822304L (en)	1983-03-23	Cephalosporin derivatives
IE822303L (en)	1983-03-23	Cephalosporin derivatives
IE822302L (en)	1983-06-23	Cephalosporin derivatives
IE822172L (en)	1983-03-08	Cephalosporin derivatives
IE821298L (en)	1982-12-22	Cephem derivatives
IE822600L (en)	1983-04-30	Cephalosporin
PH16811A (en)	1984-03-06	Cephalosporin
GB8318245D0 (en)	1983-08-10	Cephalosporin derivatives