NL193284B - Antibacterieel preparaat en een voor toepassing in dit preparaat geschikt 7-[(Z)-2-(veretherd oxyimino)-2-(2-aminothiazol-4-yl)- aceetamido]-3-ammoniomethyl-3-cefem-4-carbonzuur derivaat. - Google Patents
Antibacterieel preparaat en een voor toepassing in dit preparaat geschikt 7-[(Z)-2-(veretherd oxyimino)-2-(2-aminothiazol-4-yl)- aceetamido]-3-ammoniomethyl-3-cefem-4-carbonzuur derivaat.Info
- Publication number
- NL193284B NL193284B NL8300755A NL8300755A NL193284B NL 193284 B NL193284 B NL 193284B NL 8300755 A NL8300755 A NL 8300755A NL 8300755 A NL8300755 A NL 8300755A NL 193284 B NL193284 B NL 193284B
- Authority
- NL
- Netherlands
- Prior art keywords
- preparation
- ammoniomethyl
- aminothiazol
- cephem
- acetamido
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US35485182 | 1982-03-04 | ||
US06/354,851 US4406899A (en) | 1982-03-04 | 1982-03-04 | Cephalosporins |
US35753482A | 1982-03-12 | 1982-03-12 | |
US35753482 | 1982-03-12 |
Publications (3)
Publication Number | Publication Date |
---|---|
NL8300755A NL8300755A (nl) | 1983-10-03 |
NL193284B true NL193284B (nl) | 1999-01-04 |
NL193284C NL193284C (nl) | 1999-05-06 |
Family
ID=26998584
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL8300755A NL193284C (nl) | 1982-03-04 | 1983-03-01 | Antibacterieel preparaat en een voor toepassing in dit preparaat geschikt 7-[(Z)-2-(veretherd oxyimino)-2-(2-aminothiazol-4-yl)- aceetamido]-3-ammoniomethyl-3-cefem-4-carbonzuur derivaat. |
NL990039C NL990039I2 (nl) | 1982-03-04 | 1999-11-05 | Antibacterieel preparaat en een voor toepassing indit preparaat geschikt 7-Ä(Z)-2-(veretherd oxyimi no)-2-(2-aminothiazol-4-yl)-aceetamidoÜ-3-ammoniomethyl-3-cefem-4-carbonzuur derivaat. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL990039C NL990039I2 (nl) | 1982-03-04 | 1999-11-05 | Antibacterieel preparaat en een voor toepassing indit preparaat geschikt 7-Ä(Z)-2-(veretherd oxyimi no)-2-(2-aminothiazol-4-yl)-aceetamidoÜ-3-ammoniomethyl-3-cefem-4-carbonzuur derivaat. |
Country Status (29)
Country | Link |
---|---|
KR (1) | KR870001986B1 (nl) |
AT (2) | AT382155B (nl) |
AU (1) | AU562776B2 (nl) |
BE (1) | BE896086A (nl) |
CA (1) | CA1213882A (nl) |
CH (1) | CH654313A5 (nl) |
CS (1) | CS249512B2 (nl) |
DD (1) | DD210280A5 (nl) |
DE (1) | DE3307550A1 (nl) |
DK (1) | DK156900C (nl) |
EG (1) | EG15934A (nl) |
ES (2) | ES520224A0 (nl) |
FI (1) | FI74973C (nl) |
FR (1) | FR2522659B1 (nl) |
GB (1) | GB2116180B (nl) |
GR (1) | GR77916B (nl) |
HU (1) | HU193158B (nl) |
IE (1) | IE56647B1 (nl) |
IL (1) | IL68011A0 (nl) |
IT (1) | IT1170307B (nl) |
LU (1) | LU84674A1 (nl) |
MY (1) | MY8700943A (nl) |
NL (2) | NL193284C (nl) |
NZ (1) | NZ203312A (nl) |
PH (1) | PH18002A (nl) |
PT (1) | PT76330B (nl) |
SE (1) | SE453091B (nl) |
SU (1) | SU1250173A3 (nl) |
YU (2) | YU43822B (nl) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3409431A1 (de) * | 1983-10-08 | 1985-04-18 | Hoechst Ag, 6230 Frankfurt | Cephalosporinderivate und verfahren zu ihrer herstellung |
DE3404906A1 (de) * | 1984-02-11 | 1985-08-14 | Bayer Ag, 5090 Leverkusen | 1-oxadethiacephalosporinderivate sowie verfahren zu ihrer herstellung |
DE3419013A1 (de) * | 1984-05-22 | 1985-11-28 | Bayer Ag, 5090 Leverkusen | Neue cephalosporine und verfahren zu ihrer herstellung |
GB8424692D0 (en) * | 1984-10-01 | 1984-11-07 | Glaxo Group Ltd | Chemical compounds |
US4698336A (en) * | 1985-01-30 | 1987-10-06 | Eisai Co., Ltd. | 3-(pyrrolidinio)methyl-3-cephem derivatives |
US4910301A (en) * | 1985-08-05 | 1990-03-20 | Bristol-Myers Company | Cefepime cephalosporin salts |
FR2585705B1 (fr) * | 1985-08-05 | 1989-01-13 | Bristol Myers Co | Sels de cephalosporine et compositions injectables |
US4808617A (en) * | 1985-12-18 | 1989-02-28 | Bristol-Myers Company | Lyophilized or precipitated cephalosporin zwitterion and salt combination |
DE3789466T2 (de) * | 1986-03-17 | 1994-07-28 | Fujisawa Pharmaceutical Co | 3,7-Disubstituierte-3-Cephemverbindungen und Verfahren zu ihrer Herstellung. |
CA2011116C (en) * | 1989-03-06 | 1999-11-16 | Murray A. Kaplan | Lyophilized bmy-28142 dihydrochloride for parenteral use |
ATE201025T1 (de) | 1991-03-08 | 2001-05-15 | Biochemie Gmbh | Verfahren zur herstellung von cephalosporinen und zwischenprodukte in diesem verfahren |
YU81692A (sh) * | 1991-09-10 | 1995-03-27 | Bristol-Myers Co. | Postupak za proizvodnju cefalosporinskog antibiotika |
IL103110A (en) * | 1991-09-10 | 1997-04-15 | Bristol Myers Squibb Co | Anhydrous process for preparing cefepime dihydrochloride hydrate |
US5523400A (en) * | 1993-04-16 | 1996-06-04 | Hoffmann-La Roche Inc. | Cephalosporin antibiotics |
SI1699804T1 (sl) * | 2003-12-23 | 2008-08-31 | Sandoz Ag | Postopek za pripravo intermediatov za uporabo pri sintezi cefalosporinov |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2760484C2 (nl) * | 1976-04-14 | 1992-12-03 | Takeda Chemical Industries, Ltd., Osaka, Jp | |
GB1591439A (en) * | 1976-10-01 | 1981-06-24 | Glaxo Operations Ltd | 7-syn (oxyimino -acylamido) cephalosporins |
AR228726A1 (es) * | 1978-05-26 | 1983-04-15 | Glaxo Group Ltd | Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato |
ES485433A1 (es) * | 1978-10-27 | 1980-07-01 | Glaxo Group Ltd | Un procedimiento para la preparacion de antibioticos de ce- falosporina |
US4443444A (en) * | 1980-08-11 | 1984-04-17 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
-
1983
- 1983-02-02 CA CA000420788A patent/CA1213882A/en not_active Expired
- 1983-02-10 AU AU11304/83A patent/AU562776B2/en not_active Expired
- 1983-02-16 NZ NZ203312A patent/NZ203312A/en unknown
- 1983-02-24 DK DK086283A patent/DK156900C/da not_active IP Right Cessation
- 1983-02-28 EG EG136/83A patent/EG15934A/xx active
- 1983-02-28 CS CS831295A patent/CS249512B2/cs unknown
- 1983-03-01 FI FI830689A patent/FI74973C/fi not_active IP Right Cessation
- 1983-03-01 IT IT47826/83A patent/IT1170307B/it active
- 1983-03-01 FR FR8303334A patent/FR2522659B1/fr not_active Expired
- 1983-03-01 NL NL8300755A patent/NL193284C/nl not_active IP Right Cessation
- 1983-03-01 IL IL68011A patent/IL68011A0/xx not_active IP Right Cessation
- 1983-03-02 PH PH28591A patent/PH18002A/en unknown
- 1983-03-02 ES ES520224A patent/ES520224A0/es active Granted
- 1983-03-02 GR GR70653A patent/GR77916B/el unknown
- 1983-03-03 PT PT76330A patent/PT76330B/pt unknown
- 1983-03-03 HU HU83729A patent/HU193158B/hu unknown
- 1983-03-03 IE IE455/83A patent/IE56647B1/en not_active IP Right Cessation
- 1983-03-03 DE DE19833307550 patent/DE3307550A1/de active Granted
- 1983-03-03 SE SE8301178A patent/SE453091B/sv not_active IP Right Cessation
- 1983-03-03 CH CH1170/83A patent/CH654313A5/de not_active IP Right Cessation
- 1983-03-03 SU SU833560801A patent/SU1250173A3/ru active
- 1983-03-03 GB GB08305940A patent/GB2116180B/en not_active Expired
- 1983-03-03 DD DD83248457A patent/DD210280A5/de unknown
- 1983-03-04 KR KR1019830000871A patent/KR870001986B1/ko not_active IP Right Cessation
- 1983-03-04 LU LU84674A patent/LU84674A1/fr unknown
- 1983-03-04 BE BE0/210263A patent/BE896086A/fr not_active IP Right Cessation
- 1983-03-04 AT AT0076183A patent/AT382155B/de not_active IP Right Cessation
- 1983-03-04 YU YU523/83A patent/YU43822B/xx unknown
- 1983-10-11 ES ES526397A patent/ES8507557A1/es not_active Expired
-
1985
- 1985-08-02 AT AT0228285A patent/AT384612B/de not_active IP Right Cessation
- 1985-09-23 YU YU1496/85A patent/YU44777B/xx unknown
-
1987
- 1987-12-30 MY MY943/87A patent/MY8700943A/xx unknown
-
1999
- 1999-11-05 NL NL990039C patent/NL990039I2/nl unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
A85 | Still pending on 85-01-01 | ||
BA | A request for search or an international-type search has been filed | ||
DNT | Communications of changes of names of applicants whose applications have been laid open to public inspection |
Free format text: BRISTOL-MYERS SQUIBB COMPANY |
|
BB | A search report has been drawn up | ||
BC | A request for examination has been filed | ||
AC1 | Application for a supplementary protection certificate |
Free format text: 990039, 19991105 |
|
KC1 | Grant of a supplementary protection certificate |
Free format text: 990039, 20030301, EXPIRES: 20080228 |
|
V4 | Discontinued because of reaching the maximum lifetime of a patent |
Effective date: 20030301 |